Molecular control of development in normal and leukemic myeloid cells by cytokines, tumor suppressor and oncogenes

Current Topics in Microbiology and Immunology

Volumn 211, Issue , 1996, Pages

  Sachs, L ^a  

^a WEIZMANN INSTITUTE OF SCIENCE   (Israel)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKINE;

APOPTOSIS; CONFERENCE PAPER; HEMATOPOIESIS; HUMAN; LEUKEMIA; MOUSE; NONHUMAN; ONCOGENE; PRIORITY JOURNAL; TUMOR SUPPRESSOR GENE;

ANIMALS; CELLS, CULTURED; CYTOKINES; GENES, TUMOR SUPPRESSOR; HEMATOPOIESIS; HUMANS; LEUKEMIA, MYELOID; ONCOGENES;

EID: 3743103868     PISSN: 0070217X     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-3-642-85232-9_1     Document Type: Article

References (18)

1. Sachs L (1987) The molecular control of blood cell development Science 238:1374-1379
2. Sachs L (1990) The control of growth and differentiation in normal and leukemic blood cells. The 1989 Alfred P Sloan Prize of the General Motors Cancer Research Foundation. Cancer 65:2196-2206
3. Sachs L (1992) The molecular control of hematopoiesis: From clonal development in culture to therapy in the clinic. Int J Cell Cloning 10:196-204
4. Sachs L (1993) The molecular control of hemopoiesis and leukemia. CR Acad Sci Paris, Sciences de la vie 316:882-891
5. Sachs L (1995) The adventures of a biologist: Prenatal diagnosis, hematopoiesis, leukemia, carcinogenesis and tumor suppression. Foundations in Cancer Research. Advances Cancer Research 66:1-40
6. Lotem J, Shabo Y, Sachs L (1991) The network of hematopoietic regulatory proteins in myeloid cell differentiation. Cell Growth Differ 2:421-427
7. Blatt C, Lotem J, Sachs, L (1992) Inhibition of specific pathways of myeloid cell differentiation by an activated Hox-2.4 homeobox gene. Cell Growth Differ 3:671-676
8. Shabo Y, Lotem J, Sachs L (1990) Induction of genes for transcription factors by normal hematopoietic regulatory proteins in the differentiation of myeloid leukemic cells. Leukemia 4:797-801
9. Lotem J, Cragoe FJ, Sachs L (1991) Rescue from programmed cell death in leukemic and normal myeloid cells. Blood 78:953-960
10. Lotem J, Sachs L (1992) Hematopoietic cytokines inhibit apoptosis induced by transforming growth factor β1 and cancer chemotherapy compounds in myeloid leukemic cells. Blood 80:1750-1757
11. Sachs L, Lotem J (1993) Control of programmed cell death in normal and leukemic cells: New implications for therapy. Blood 82:15-21
12. Sachs L, Lotem, J (1995) Apoptosis in the hemopoietic system. In: Gregory CD (ed) Apoptosis and the Immune Response. Wiley, New York, pp 371-403
13. Lotem J, Sachs L (1995) Interferon-γ inhibits apoptosis induced by wild-type p53, cytotoxic anti-cancer agents and viability factor deprivation in myeloid cells. Leukemia 9:685-692
14. Yonish-Rouach E, Resnitzky D, Lotem J, Sachs L, Kimchi A, Oren M (1991) Wild type p53 induces apoptosis of myeloid leukaemic cells that is inhibited by interleukin 6. Nature 352:345-347
15. Lotem J, Sachs L (1993) Regulation by bcl-2, c-myc and p53 of susceptibility to induction of apoptosis by heat shock and cancer chemotherapy compounds in differentiation competent and defective myeloid leukemic cells. Cell Growth Differ 4:41-47
16. Lotem J, Sachs L (1993) Hematopoietic cells from mice deficient in wild-type p53 are more resistant to induction of apoptosis by some agents. Blood 82:1092-1096
17. Lotem J, Sachs L (1994) Control of sensitivity to induction of apoptosis in myeloid leukemic cells by differentiation and bcl-2 dependent and independent pathways. Cell Growth Differ 5:321-327
18. L and bax in the control of apoptosis by hematopoietic cytokines and dexamethasone. Cell Growth Differ 6:647-653