Clinical predictors of response to cognitive-behavioral therapy for obsessive-compulsive disorder

Clinical Psychology Review

Volumn 28, Issue 1, 2008, Pages 118-130

  Keeley, Mary L ^a,b   Storch, Eric A ^b   Merlo, Lisa J ^b   Geffken, Gary R ^b  

^a UNIVERSITY OF FLORIDA   (United States)

^b UNIVERSITY OF FLORIDA COLLEGE OF MEDICINE   (United States)

Author keywords

Cognitive behavioral therapy; Obsessive compulsive disorder; Outcome; Predictors; Review; Treatment

Indexed keywords

CHILD PSYCHOLOGY; COGNITION; COGNITIVE THERAPY; COMORBIDITY; DEMOGRAPHY; DEPRESSION; DISEASE DURATION; DISEASE SEVERITY; FAMILY; FAMILY STRESS; GENERALIZED ANXIETY DISORDER; HORMONE ACTION; HUMAN; INTERVENTION STUDY; INTROSPECTION; MOTIVATION; OBSESSIVE COMPULSIVE DISORDER; ONSET AGE; OUTCOME ASSESSMENT; PANIC; PATIENT COMPLIANCE; PERSONALITY DISORDER; POSTTRAUMATIC STRESS DISORDER; PREDICTOR VARIABLE; RESEARCH; REVIEW; SEX DIFFERENCE; SOCIAL PHOBIA; SYMPTOM; TREATMENT INDICATION; TREATMENT OUTCOME; TREATMENT RESPONSE;

ADULT; CLINICAL TRIALS AS TOPIC; COGNITIVE THERAPY; COMORBIDITY; FEMALE; HUMANS; MALE; OBSESSIVE-COMPULSIVE DISORDER; PERSONALITY DISORDERS; PROGNOSIS; SEVERITY OF ILLNESS INDEX; TREATMENT OUTCOME;

EID: 37349128221     PISSN: 02727358     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cpr.2007.04.003     Document Type: Review

References (102)

1. Abramowitz J.S. Effectiveness of psychological and pharmacological treatments for obsessive-compulsive disorder: A quantitative review. Journal of Consulting and Clinical Psychology 65 (1997) 44-52
2. Abramowitz J.S. Treatment of obsessive-compulsive disorder in patients who have comorbid depression. Journal of Clinical Psychology 60 (2004) 1133-1141
3. *Abramowitz J.S., and Foa E.B. Does comorbid major depressive disorder influence outcome of exposure and response prevention for OCD?. Behavior Therapy 31 (2000) 795-800
4. *Abramowitz J.S., Franklin M.E., and Foa E.B. Empirical status of cognitive-behavioral therapy for obsessive-compulsive disorder: A meta-analytic review. Romanian Journal of Cognitive & Behavioral Psychotherapies 2 (2002) 89-104
5. *Abramowitz J.S., Franklin M.E., Street G., Kozak M., and Foa E.B. Effects of comorbid depression on response to treatment for obsessive-compulsive disorder. Behavior Therapy 31 (2000) 517-528
6. *Abramowitz J.S., Franklin M.E., Schwartz S.A., and Furr J.M. Symptom presentation and outcome of cognitive-behavioral therapy for obsessive-compulsive disorder. Journal of Consulting and Clinical Psychology 71 (2003) 1049-1057
7. Abramowitz J.S., Taylor S., and McKay D. Potential and limitations of cognitive treatments for obsessive-compulsive disorder. Cognitive Behaviour Therapy 34 (2005) 140-147
8. Abramowitz, J.S., Storch, E.A., Keeley, M.L., & Cordell, E. (in press). Obsessive-compulsive disorder with comorbid major depression: What is the role of cognitive factors? Behaviour Research and Therapy.
9. Abramowitz J.S., Whiteside S.P., and Deacon B.J. The effectiveness of treatment for pediatric obsessive-compulsive disorder: A meta-analysis. Behavior Therapy 36 (2005) 55-63
10. American Psychiatric Association. Diagnostic and statistical manual of mental disorders - fourth edition - text revision (2000), Author, Washington, DC
11. *Amir N., Freshman M., and Foa E.B. Family distress and involvement in relatives of obsessive-compulsive disorder patients. Journal of Anxiety Disorders 14 (2000) 209-217
12. *Alonso P., Menchon J.M., Pifarre J., Mataix-Cols D., Torres L., Salgado P., et al. Long-term follow-up and predictors of clinical outcome in obsessive-compulsive patients treated with serotonin reuptake inhibitors and behavioral therapy. Journal of Clinical Psychiatry 62 (2001) 535-540
13. Baron R.M., and Kenny D.A. The moderator-mediator variable distinction in social psychological research: Conceptual, strategic, and statistical considerations. Journal of Personality and Social Psychology 51 (1986) 1173-1182
14. *Barrett P., Farrell L., Dadds M., and Boulter N. Cognitive-behavioral family treatment of childhood obsessive-compulsive disorder: Long-term follow-up and predictors of outcome. Journal of the American Academy of Child and Adolescent Psychiatry 44 (2005) 1005-1014
15. Barrett P., Healy-Farrell L., and March J.S. Cognitive-behavioral family treatment of childhood obsessive-compulsive disorder: A controlled trial. Journal of the American Academy of Child and Adolescent Psychiatry 43 (2004) 46-62
16. *Benazon N.R., Ager J., and Rosenberg D.R. Cognitive behavior therapy in treatment-naïve children and adolescents with obsessive-compulsive disorder: An open trial. Behavior Research and Therapy 40 (2002) 529-539
17. *Bolton D., Raven P., Madronal-Luque R., and Marks I.M. Neurological and neuropsychological signs in obsessive-compulsive disorder: Interaction with behavioural treatment. Behavior Research and Therapy 38 (2000) 695-708
18. *Brody A.L., Saxena S., Schwartz J.M., Stoessel P.W., Maidment K., Phelps M.E., et al. FDG-PET predictors of response to behavioral therapy and pharmacotherapy in obsessive compulsive disorder. Psychiatry Research 84 (1998) 1-6
19. *Buchanan A.W., Meng K.S., and Marks I.M. What predicts improvement and compliance during behavioral treatment of obsessive compulsive disorder?. Anxiety 2 (1996) 22-27
20. Carmin C.N., Pollard C.A., and Ownby R.L. Cognitive behavioral treatment of older adults with obsessive-compulsive disorder. Cognitive and Behavioral Practice 6 (1999) 110-119
21. Carver C.S., and Scheier M. On the self-regulation of behavior (1998), Cambridge University Press, New York
22. Castle D.J., Deale A., and Marks I.M. Gender differences in obsessive-compulsive disorder. Australian and New Zealand Journal of Psychiatry 29 (1995) 114-117
23. *Chambless D.L., and Steketee G. Expressed emotion and behavior therapy outcome: A prospective study with obsessive-compulsive and agoraphobic patients. Journal of Consulting and Clinical Psychology 67 (1999) 658-665
24. Christensen D.D., and Greist J.H. The challenge of obsessive-compulsive disorder hoarding. Primary Psychiatry 8 (2001) 79-86
25. Creed T.A., and Kendall P.C. Therapist alliance-building behavior within a cognitive-behavioral treatment for anxiety in youth. Journal of Consulting and Clinical Psychology 73 (2005) 498-505
26. *De Araujo L.A., Ito L.M., and Marks I.M. Early compliance and other factors predicting outcome of exposure for obsessive-compulsive disorder. British Journal of Psychiatry 169 (1996) 747-752
27. de Haan E. Effective treatment of OCD?. Journal of the American Academy of Child and Adolescent Psychiatry 45 (2006) 383
28. Douglass H.M., Moffit T.E., Dar R., McGee R., and Silva P. Obsessive compulsive disorder in a birth cohort of 18 year olds: Prevalence and predictors. Journal of the American Academy of Child and Adolescent Psychiatry 34 (1995) 1424-1431
29. Eisen J.L., Phillips K.A., Baer L., Beer D.A., Atala K.D., and Rasmussen S.A. The Brown Assessment of Beliefs Scale: Reliability and validity. American Journal of Psychiatry 155 (1998) 102-108
30. *Emmelkamp P.M.G., de Haan E., and Hoogduin C.A.L. Marital adjustment and obsessive-compulsive disorder. British Journal of Psychiatry 156 (1990) 55-60
31. *Emmelkamp P.M.G., Hoekstra R.J., and Visser A. The behavioral treatment of obsessive-compulsive disorder: Prediction of outcome at 3, 5 years follow-up. In: Pichot P., Berner P., Wolf R., and Thau K. (Eds). Psychiatry: The state of the art (1985), Plenum, New York 265-270
32. Fama J., and Wilhelm S. Formal cognitive therapy: A new treatment for OCD. In: Abramowitz J.S. (Ed). Concepts and controversies in obsessive-compulsive disorder (2005), Springer Science, New York, NY 263-304
33. *Foa E.B. Failure in treating obsessive-compulsive disorder. Behaviour Research and Therapy 17 (1979) 169-176
34. *Foa E.B., Abramowitz J.S., Franklin M.E., and Kozak M.J. Feared consequences, fixity of belief, and treatment outcome in patients with obsessive-compulsive disorder. Behavior Therapy 30 (1999) 717-724
35. *Foa E.B., Grayson J.B., Steketee G.S., Doppelt H.G., Turner R.M., and Latimer P.R. Success and failure in the behavioral treatment of obsessive-compulsives. Journal of Consulting and Clinical Psychology 51 (1983) 287-297
36. Foa E.B., and Kozak M.J. Emotional processing of fear: Exposure to corrective information. Psychological Bulletin 99 (1986) 20-35
37. *Foa E.B., Liebowitz M.R., Kozak M.J., Davies S., Campeas R., Franklin M.E., et al. Randomized, placebo-controlled trial of exposure and ritual prevention, clomipramine, and their combination in the treatment of obsessive-compulsive disorder. American Journal of Psychiatry 162 (2005) 151-161
38. *Foa E.B., Steketee G., Grayson J.B., and Doppelt H.G. reatment of obsessive-compulsives: When do we fail?. In: Foa E.B., and Emmelkamp P.M.G. (Eds). Failures in behavior therapy (1983), Wiley & Sons, New York 10-34
39. *Franklin M.E., Abramowitz J.S., Kozak M.J., Levitt J.T., and Foa E.B. Effectiveness of exposure and ritual prevention for obsessive-compulsive disorder: Randomized compared with nonrandomized samples. Journal of Consulting and Clinical Psychology 68 (2000) 594-602
40. *Freeston M.H., Ladouceur R., Gagnon F., Thibodeau N., Rheaume J., Letarte H., et al. Cognitive-behavioral treatment of obsessive thoughts: A controlled study. Journal of Consulting and Clinical Psychology 65 (1997) 405-413
41. *Fricke S., Moritz S., Andresen B., Jacobson D., Kloss M., Rufer M., et al. Do personality disorders predict negative treatment outcome in obsessive-compulsive disorders? A prospective 6-month follow-up study. European Psychiatry 21 (2006) 319-324
42. Geller D., Biederman J., Jones J., Park K., Schwartz S., Shapiro S., et al. Is juvenile obsessive-compulsive disorder a developmental subtype of the disorder? A review of the pediatric literature. Journal of the American Academy of Children and Adolescent Psychiatry 37 (1998) 420-427
43. Goodman W.K., Price L.H., Rasmussen S.A., Mazure C., Fleischman R.L., Hill C.L., et al. The Yale-Brown Obsessive Compulsive Scale: I. Development, use, and reliability. Archives of General Psychiatry 46 (1989) 1006-1011
44. Haby M.M., Donnelly M., Corry J., and Vos T. Cognitive behavioural therapy for depression, panic disorder, and generalized anxiety disorder: A meta-regression of factors that may predict outcome. Australian and New Zealand Journal of Psychiatry 40 (2006) 9-19
45. *Himle J.A., Fischer D.J., Van Etten M.L., Janeck A.S., and Hanna G.L. Group behavioral therapy for adolescents with tic-related and non-tic-related obsessive-compulsive disorder. Depression and Anxiety 17 (2003) 73-77
46. *Hoogduin C.A.L., and Duivenvoorden H.J. A decision model in the treatment of obsessive-compulsive neurosis. British Journal of Psychiatry 152 (1988) 516-521
47. *Hooduin C.A.L., de Haan E., and Schaap C. The significance of the patient-therapist relationship in the treatment of obsessive-compulsive neurosis. British Journal of Clinical Psychology 28 (1989) 185-186
48. Huppert J.D., Ledley D., and Foa E.B. The use of homework in behavior therapy for anxiety disorders. Journal of Psychotherapy Integration 16 (2006) 128-139
49. Jacobson N.S., and Truax P. Clinical significance: A statistical approach to defining meaningful change in psychotherapy research. Journal of Consulting and Clinical Psychology 59 (1991) 12-19
50. Karno M., Golding J.M., Sorenson S.B., and Burnam M.A. The epidemiology of obsessive-compulsive disorder in five US communities. Archives of General Psychiatry 45 (1988) 1094-1099
51. *Keijsers G.P., Hoogduin C.A., and Schaap C.P. Predictors of treatment outcome in the behavioural treatment of obsessive-compulsive disorder. British Journal of Psychiatry 165 (1994) 781-786
52. Keijsers G.P., Schaap C.P., and Hoogduin C.A. The impact of interpersonal patient and therapist behavior on outcome in cognitive-behavior therapy. A review of empirical studies. Behavior Modification 24 (2000) 264-297
53. *Knox L.S., Albano A.M., and Barlow D.H. Parental involvement in the treatment of childhood obsessive-compulsive disorder: A multiple baseline examination incorporating parents. Behavior Therapy 27 (1996) 93-114
54. Kraemer H.C., Wilson G.T., Fairburn C.G., and Agras W.S. Mediators and moderators of treatment effects in randomized clinical trials. Archives of General Psychiatry 59 (2002) 877-883
55. *Lax R., Basoglu M., and Marks I.M. Expectancy and compliance as predictors of outcome in obsessive-compulsive disorder. Behavior Research and Therapy 32 (1992) 343-353
56. Lewin A.B., Storch E.A., Merlo L.J., Adkins J.W., Murphy T.K., and Geffken G.R. Intensive cognitive behavioral therapy for pediatric obsessive compulsive disorder: A treatment protocol for mental health providers. Psychological Services 2 (2005) 91-104
57. Lochner C., Hemmings S.M.J., Kinnear C.J., Moolman-Smook J.C., Corfield V.A., Knowles J.A., et al. Gender in obsessive-compulsive disorder: Clinical and genetic findings. European Neuropsychopharmacology 14 (2004) 105-113
58. March J.S., and Mulle K. OCD in children and adolescents: A cognitive behavioral treatment manual (1998), Guilford, New York
59. *Mataix-Cols D., Marks I.M., Greist J.H., Kobak K.A., and Baer L. Obsessive-compulsive symptom dimensions as predictors of compliance with and response to behaviour therapy: Results from a controlled trial. Psychotherapy and Psychosomatics 71 (2002) 255-262
60. Mataix-Cols D., Rauch S.L., Manzo P.A., Jenike M.A., and Baer L. Use of factor-analyzed symptom dimensions to predict outcome with serotonin reuptake inhibitors and placebo in treatment of obsessive-compulsive disorder. American Journal of Psychiatry 156 (1999) 1409-1416
61. *Mehta M. A comparative study of family-based and patient-based behavioral management in obsessive-compulsive disorder. British Journal of Psychiatry 157 (1990) 133-135
62. *Merlo, L.J., Lehmkuhl, H.D., Storch, E.A. (in preparation). Family accommodation predicts cognitive-behavioral therapy treatment response in pediatric obsessive-compulsive disorder.
63. *Minichiello W., Baer L., and Jenike M.A. Schizotypal personality disorder: A poor prognostic indicator for behavior therapy in the treatment of obsessive-compulsive disorder. Journal of Anxiety Disorders 1 (1987) 273-276
64. *Moritz S., Fricke S., Jacobsen D., Kloss M., Wein C., Rufer M., et al. Positive schizotypal symptoms predict treatment outcome in obsessive-compulsive disorder. Behavior Research and Therapy 42 (2004) 217-227
65. *Moritz S., Kloss M., Jacobsen D., Fricke S., Cutler C., Brassen S., et al. Neurocognitive impairment does not predict treatment outcome in obsessive-compulsive disorder. Behavior Research Therapy 43 (2005) 811-819
66. *McLean P.D., Whittal M.L., Thordarson D.S., Taylor S., Sochting I., et al. Cognitive versus behavior therapy in the group treatment of obsessive-compulsive disorder. Journal of Consulting and Clinical Psychology 69 (2001) 205-214
67. Nestadt G., Samuels J., Riddle M., Liang K., Bienvenu O., Hoehn-Saric R., et al. The relationship between obsessive-compulsive disorder and anxiety and affective disorders: Results from the Johns Hopkins OCD Family Study. Psychological Medicine 31 (2001) 481-487
68. Obsessive Compulsive Cognitions Working Group. Development and initial validation of the obsessive belief questionnaire and interpretation of intrusions inventory. Behaviour Research and Therapy 39 (2001) 987-1006
69. Obsessive Compulsive Cognitions Working Group. Psychometric validation of the obsessive belief questionnaire and interpretation of intrusions inventory: Part I. Behaviour Research and Therapy 41 (2003) 863-878
70. Obsessive Compulsive Cognitions Working Group. Psychometric validation of the obsessive belief questionnaire and interpretation of intrusions inventory - part 2: Factor analyses and testing of a brief version. Behaviour Research and Therapy 43 (2005) 1537-1542
71. Otto M.W., Pollack M.H., Gould R.A., Worthington III J.J., McArdle E.T., and Rosenbaum J.F. A comparison of the efficacy of clonazepam and cognitive-behavioral group therapy for the treatment of social phobia. Journal of Anxiety Disorders 14 (2000) 345-358
72. Pauls D.L., Alsobrook J.P., Goodman W., Rasmussen S., and Leckman D.L. A family study of obsessive-compulsive disorder. American Journal of Psychiatry 152 (1995) 76-84
73. Pediatric OCD Treatment Study (POTS) Team. Cognitive-behavior therapy, sertraline, and their combination for children and adolescents with obsessive-compulsive disorder. Journal of the American Medical Association 292 (2004) 1969-1976
74. *Piacentini J., Bergman R.L., Jacobs C., McCracken J.T., and Kretchman J. Open trial of cognitive behavior therapy for childhood obsessive-compulsive disorder. Journal of Anxiety Disorders 16 (2002) 207-219
75. Purdon C., and Clark D.A. Meta-cognition and obsessions. Clinical Psychology and Psychotherapy 6 (1999) 96-101
76. Reich J. The effect of axis II disorders on the outcome of treatment of anxiety and unipolar depressive disorder: A review. Journal of Personality Disorders 17 (2003) 387-405
77. *Renshaw K.D., Steketee G., and Chambless D. Involving family members in the treatment of OCD. Cognitive Behaviour Therapy 34 (2005) 164-176
78. Riddle M.A. Obsessive-compulsive disorder in children and adolescents. British Journal of Psychiatry 173 S135 (1998) 91-96
79. *Riggs D.S., Hiss H., and Foa E.B. Marital distress and the treatment of obsessive-compulsive disorder. Behavior Therapy 23 (1992) 585-597
80. Robins L.N., Helzer J.E., Weissman M.M., and Orvaschel H. Lifetime prevalence of specific psychiatric disorders in three sites. Archives of General Psychiatry 41 (1984) 949-958
81. *Rufer M., Fricke S., Moritz S., Kloss M., and Hand I. Symptom dimensions in obsessive-compulsive disorder: Prediction of cognitive-behavior therapy outcome. Acta Psychiatrica Scandanavia 113 (2006) 440-446
82. *Rufer M., Hand I., Alsleben H., Braatz A., Ortmann J., Katenkamp B., et al. Long-term course and outcome of obsessive-compulsive patients after cognitive-behavioral therapy in combination with either fluvoxamine or placebo: A 7-year follow-up of a randomized double-blind trial. Comprehensive Psychiatry 47 (2005) 394-398
83. *Rufer M., Held D., Cremer J., Fricke S., Moritz S., Peter H., et al. Dissociation as a predictor of cognitive behavior therapy outcome in patients with obsessive-compulsive disorder. Psychotherapy and Psychosomatics 75 (2006) 40-46
84. Salkovskis P. Understanding and treating obsessive-compulsive disorder. Behavior Research and Therapy Supplement 37 (1999) S29-S52
85. Sookman D., Abramowitz J.S., Calamari J.E., Wilhelm S., and McKay D. Subtypes of obsessive-compulsive disorder: Implications for specialized cognitive-behavior therapy. Behavior Therapy 36 (2005) 393-400
86. Stanley M.A., and Turner S.M. Current status of pharmacological and behavioral treatment of obsessive-compulsive disorder. Behavior Therapy 26 (1995) 163-186
87. *Steketee G. Social support and treatment outcome of obsessive-compulsive disorder at 9-month follow-up. Behavioral Psychotherapy 21 (1993) 81-95
88. *Steketee G.S., Chambless D.L., and Tran G. Effects of axis I and II comorbidity on behavior therapy outcome for obsessive-compulsive disorder and agoraphobia. Comprehensive Psychiatry 42 (2001) 76-86
89. Steketee G., and Frost R. Compulsive hoarding: Current status of the research. Clinical Psychology Review 23 (2003) 905-927
90. Steketee G., and Shapiro L.J. Predicting behavioral treatment outcome for agoraphobia and obsessive compulsive disorder. Clinical Psychology Review 15 (1995) 317-346
91. Stewart S.E., Stack D.E., Farrell C., Pauls D.L., and Jenike M.A. Effectiveness of intensive residential treatment (IRT) for severe, refractory obsessive-compulsive disorder. Journal of Psychiatric Research 39 (2005) 603-609
92. *Storch, E.A., Larson, M.J., Merlo, L.J., Keeley, M.L., Jacob, M.L., Geffken, G.R., et al. (in press). Comorbidity of pediatric obsessive-compulsive disorder and anxiety disorders: Impact on symptom severity, emotional functioning, and impairment. Journal of Behavioral Assessment and Psychopathology.
93. Storch E.A., Geffken G.R., Merlo L.J., Mann G., Duke D., Munson M., et al. Cognitive-behavioral therapy for pediatric obsessive-compulsive disorder: Comparison of intensive and weekly approaches. Journal of the American Academy of Child and Adolescent Psychiatry 46 (2007) 469-478
94. Storch E.A., and Merlo L.J. Obsessive-compulsive disorder: Strategies for using CBT and pharmacotherapy. Journal of Family Practice 55 (2006) 329-333
95. Taylor S., Abramowitz J.S., and McKay D. Are there interactions among dysfunctional beliefs in obsessive compulsive disorder?. Cognitive Behaviour Therapy 24 (2005) 89-98
96. *Tolin D.F., Maltby N., Diefenbach G.J., Hannan S.E., and Worhunsky P. Cognitive-behavioral therapy for medication nonresponders with obsessive-compulsive disorder: A wait-list-controlled open trial. Journal of Clinical Psychiatry 65 (2004) 922-931
97. van Minnen A., Arntz A., and Keijsers G.P. Prolonged exposure in patients with chronic PTSD: Predictors of treatment outcome and dropout. Behavior Research and Therapy 40 (2002) 439-457
98. *Vogel P.A., Hansen B., Stiles T.C., and Gotestam K.G. Treatment motivation, treatment expectancy, and helping alliance as predictors of outcome in cognitive behavioral treatment of OCD. Journal of Behavior Therapy and Experimental Psychiatry 37 (2006) 247-255
99. *Whittal M.L., Thordarson D.S., and McLean P.D. Treatment of obsessive-compulsive disorder: Cognitive behavior therapy vs exposure and response prevention. Behavior Research and Therapy 43 (2005) 1559-1576
100. *Woods C.M., Chambless D.L., and Steketee G. Homework compliance and behavior therapy for panic with agoraphobia and obsessive-compulsive disorder. Cognitive Behaviour Therapy 31 (2002) 88-95
101. Zohar A.H. The epidemiology of obsessive-compulsive disorder in children and adolescents. Child and Adolescent Psychiatric Clinics of North America 8 (1999) 445-460
102. Zohar J., Gross-Isseroff R., Hermesh H., and Weizman A. Is there sexual dimorphism in obsessive-compulsive disorder?. Neuroscience and Biobehavioral Reviews 23 (1999) 845-849