Genes influencing milk production traits predominantly affect one of four biological pathways

Genetics Selection Evolution

Volumn 40, Issue 1, 2008, Pages 79-89

  Chamberlain, Amanda Jane ^a   McPartlan, Helen Clare ^a   Goddard, Michael Edward ^a  

^a DEPARTMENT OF PRIMARY INDUSTRIES   (Australia)

Author keywords

Bivariate analysis; False discovery rate; Genome scan; Independent traits; Pleiotropy

Indexed keywords

ESTIMATION METHOD; FAT; GENE EXPRESSION; GENOME; MAMMAL; MILK PRODUCTION; PLEIOTROPY; PROTEIN;

ANIMAL; ARTICLE; BIOLOGICAL MODEL; DAIRYING; FEMALE; GENETIC LINKAGE; GENETICS; LACTATION; MILK; PRODUCTIVITY; QUANTITATIVE TRAIT LOCUS; SIGNAL TRANSDUCTION;

ANIMALS; DAIRYING; EFFICIENCY; FEMALE; LACTATION; LINKAGE (GENETICS); MILK; MODELS, GENETIC; QUANTITATIVE TRAIT LOCI; SIGNAL TRANSDUCTION;

EID: 37349119135     PISSN: 0999193X     EISSN: 12979686     Source Type: Journal    
DOI: 10.1051/gse:2007038     Document Type: Article

References (8)

1. Blott S., Kim J.J., Moisio S., Schmidt-Kuntzel A., Cornet A., Berzi P., Cambisano N., Ford C., Grisart B., Johnson D., Karim L., Simon P., Snell R., Spelman R., Wong J., Vilkki J., Georges M., Farnir F., Coppieters W., Molecular dissection of a quantitative trait locus: A phenylalanine-to-tyrosine substitution in the transmembrane domain of the bovine growth hormone receptor is associated with a major effect on milk yield and composition, Genetics 163 (2003) 253-266.
2. Chamberlain A., Mapping quantitative trait loci for milk production traits in dairy cattle and using them in marker assisted selection, Institute of Land and Food Resources, University of Melbourne, Melbourne, 2004, pp. 218.
3. Cohen-Zinder M., Seroussi E., Larkin D.M., Loor J.J., Everts-van der Wind A., Lee J.H., Drackley J.K., Band M.R., Hernandez A.G., Shani M., Lewin H.A., Weller J.I., Ron M., Identification of a missense mutation in the bovine ABCG2 gene with a major effect on the QTL on chromosome 6 affecting milk yield and composition in Holstein cattle, Genome Res. 15 (2005) 936-944.
4. Grisart B., Coppieters W., Farnir F., Karim L., Ford C., Berzi P., Cambisano N., Mni M., Reid S., Simon P., Spelman R., Georges M., Snell R., Positional candidate cloning of a QTL in dairy cattle: Identification of a missense mutation in the bovine DGAT1 gene with major effect on milk yield and composition, Genome Res. 12 (2002) 222-231.
5. Lipkin E., Grosman G., Tchourzyna E., Friedmann A., Soller M., QTL affecting milk protein percent also affect milk yield and protein yield, in: Proceedings of 7th World Congress on Genetics Applied to Livestock Production, 19-23 August 2002, Montpellier, France.
6. Lynch M., Walsh B., Genetics and Analysis of Quantitative Traits, Sinauer Associates, Inc., Sunderland, USA, 1998.
7. Seaton G., Haley C.S., Knott S.A., Kearsey M., Visscher P.M., QTL Express: mapping quantitative trait loci in simple and complex pedigrees, Bioinformatics 18 (2002) 339-340.
8. Wright S., Evolution and the genetics of populations, University of Chicago Press, Chicago, USA, 1968.