Methods for assessing pharmacodynamic interactions

Antiepileptic Drugs: Combination Therapy and Interactions

Volumn , Issue , 2005, Pages 193-207

  Bourgeois, Blaise F D ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 37349113763     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1017/CBO9780511545023.012     Document Type: Chapter

References (18)

1. Borowicz KK, Rafal K, Gasior M, et al. Influence of melatonin upon the protective action of conventional anti-epileptic drugs against maximal electroshock in mice. Eur Neuropsychopharmacol1999; 9: 185–190.
2. Bourgeois BFD. Antiepileptic drug combinations and experimental background: the case of phenobarbital and phenytoin. Naunyn-Schmiedeberg’s Arch Pharmacol1986; 333: 406–411.
3. Bourgeois BFD. Combination of valproate and ethosuximide: antiepileptic and neurotoxic interaction. J Pharmacol Exp Ther1988; 237: 1128–1132.
4. Bourgeois BFD, Wad N. Combined administration of carbamazepine and phenobarbital: effect on anticonvulsant activity and neurotoxicity. Epilepsia1988; 29: 482–487.
5. Bourgeois BFD, Dodson WE, Ferrendelli JA. Potentiation of the antiepileptic activity of phenobarbital by nicotinamide. Epilepsia1983; 23: 238–244.
6. Chen G, Ensor CR. A study of the anticonvulsant properties of phenobarbital and dilantin. Arch Int Pharmacodyn1954; 100: 234–248.
7. Consroe P, Wolkin A. Cannabidiol – antiepileptic drug comparisons and interactions in experimentally induced seizures in rats. J Pharmacol Exp Ther1977; 201: 26–32.
8. Elison G, Singer S, Hitchings GH. Antagonists of nucleic acid derivatives. VIII. Synergism in combinations of biochemically related antimetabolites. J Biol Chem1954; 208: 477–488.
9. Gordon R, Gels M, Wichmann J, et al. Interaction of felbamate with several other antiepileptic drugs against seizures induced by maximal electroshock in mice. Epilepsia1993; 34: 367–371.
10. Hewlett PS. Measurement of the potencies of drug mixtures. Biometrics1969; 25: 477–487.
11. Kerry DW, Hamilton-Miller JMT, Brumfitt W. Trimethoprim and rifampicin: in vitro activities separately and in combination. J Antimicrob Agents Chemother1975; 1: 1417–1427.
12. Leppik IE, Sherwin AL. Anticonvulsant activity of phenobarbital and phenytoin in combination. J Pharmacol Exp Ther1977; 200: 570–575.
13. Levasseur LM, Delon A, Greco WR, et al. Development of a new quantitative approach for the isobolographic assessment of the convulsant interaction between pefloxacin and theophylline in rats. Pharmaceut Res1998; 15: 1069–1076.
14. Loewe S. The problem of synergism and antagonism of combined drugs. Arzneimittelforsch1953; 3: 285–290.
15. Masuda Y, Utsui Y, Shiraishi Y, et al. Evidence for a synergistic interaction between phenytoin and phenobarbital in experimental animals. J Pharmacol Exp Ther1981; 217: 805–811.
16. Vinik R, Bradley E, Kissin I. Isobolographic analysis of propofol–thiopental hypnotic interaction in surgical patients. Anesth Analg1999; 88: 667–670.
17. Wallin RF, Blackburn WH, Napoli. Pharmacological interactions of albutoin with other anticonvulsant drugs. Pharmacol Exp Ther1970; 174: 276–282.
18. Weaver LC, Swinyard EA, Woodbury LA, et al. Studies on anticonvulsant drug combinations: phenobarbital and diphenylhydantoin. J Pharmacol Exp Ther1955; 113: 359–370.