Direct effect of human immunodeficiency virus protease inhibitors on neutrophil function and apoptosis via calpain inhibition

Clinical and Vaccine Immunology

Volumn 14, Issue 11, 2007, Pages 1515-1521

  Hadad, Nurit ^a,b   Levy, Rachel ^a   Schlaeffer, Francise ^a   Riesenberg, Klaris ^a  

^a BEN GURION UNIVERSITY OF THE NEGEV   (Israel)

^b BEN GURION UNIVERSITY OF THE NEGEV   (Israel)

Author keywords

[No Author keywords available]

Indexed keywords

CALPAIN; CALPAIN 1; FORMYLMETHIONYLLEUCYLPHENYLALANINE; ISOTHIOCYANIC ACID; LIPOCORTIN 5; LOPINAVIR; NELFINAVIR; PHORBOL 13 ACETATE 12 MYRISTATE; PROTEINASE INHIBITOR; RITONAVIR; SAQUINAVIR; SUPEROXIDE; ZYMOSAN;

ANALYTIC METHOD; APOPTOSIS; ARTICLE; CELL FUNCTION; CELL MIGRATION; CELL STRUCTURE; CHEMOTAXIS; CONTROLLED STUDY; DNA FRAGMENTATION; FLUORESCENCE; HUMAN; HUMAN CELL; NEUTROPHIL; NORMAL HUMAN; PHAGOCYTOSIS; PRIORITY JOURNAL;

APOPTOSIS; CALPAIN; HIV PROTEASE INHIBITORS; HUMANS; NEUTROPHILS;

EID: 37349071363     PISSN: 15566811     EISSN: 1556679X     Source Type: Journal    
DOI: 10.1128/CVI.00130-07     Document Type: Article

References (2)

1. Akgul, C., D. A. Moulding, and S. W. Edwards. 2001. Molecular control of neutrophil apoptosis. FEBS Lett. 487:318-322.
2. Altznauer, F., S. Conus, A. Cavalli, G. Folkers, and H. U. Simon. 2004. Calpain-1 regulates Bax and subsequent Smac-dependent caspase-3 activation in neutrophil apoptosis. J. Biol. Chem. 279:5947-5957.