Bone regeneration in dehiscence-type defects at non-submerged and submerged chemically modified (SLActive®) and conventional SLA titanium implants: An immunohistochemical study in dogs

Journal of Clinical Periodontology

Volumn 35, Issue 1, 2008, Pages 64-75

  Schwarz, Frank ^a   Sager, Martin ^a   Ferrari, Daniel ^a   Herten, Monika ^a   Wieland, Marco ^b   Becker, Jürgen ^a  

^a HEINRICH HEINE UNIVERSITY   (Germany)

^b INSTITUT STRAUMANN AG   (Switzerland)

Author keywords

Animal study; Bone regeneration; Dehiscence type defect; Hydrophilic titanium surface; Immunohistochemistry

Indexed keywords

BIOMATERIAL; TITANIUM;

ANIMAL; ARTICLE; BONE REGENERATION; DOG; HISTOLOGY; JAW; PHYSIOLOGY; RANDOMIZATION; SURFACE PROPERTY; TIME; TOOTH IMPLANTATION; WOUND DEHISCENCE;

ALVEOLAR PROCESS; ANIMALS; BONE REGENERATION; COATED MATERIALS, BIOCOMPATIBLE; DENTAL IMPLANTS; DOGS; RANDOM ALLOCATION; SURFACE PROPERTIES; SURGICAL WOUND DEHISCENCE; TIME FACTORS; TITANIUM;

EID: 37349048918     PISSN: 03036979     EISSN: 1600051X     Source Type: Journal    
DOI: 10.1111/j.1600-051X.2007.01159.x     Document Type: Article

References (32)

1. Becker, W., Becker, B. E., Handlesman, M., Celletti, R., Ochsenbein, C., Hardwick, R. Langer, B. (1990) Bone formation at dehisced dental implant sites treated with implant augmentation material: a pilot study in dogs. International Journal of Periodontics and Restorative Dentistry 10, 92 101.
2. Bornstein, M. M., Valderrama, P., Jones, A., Wilson, T. G., Seibl, R. Cochran, D. L. (2007) Bone apposition around two different sand-blasted and acid-etched titanium implant surfaces. A histomorphometric study in canine mandibles. Clinical Oral Implants Research (in press).
3. Buser, D., Broggini, N., Wieland, M., Schenk, R. K., Denzer, A. J., Cochran, D. L., Hoffmann, B., Lussi, A. Steinemann, S. G. (2004) Enhanced bone apposition to a chemically modified SLA titanium surface. Journal of Dental Research 83, 529 533.
4. Casati, M. Z., Sallum, E. A., Nociti, F. H. Jr., Caffesse, R. G. Sallum, A. W. (2002) Enamel matrix derivative and bone healing after guided bone regeneration in dehiscence-type defects around implants. A histomorphometric study in dogs. Journal of Periodontology 73, 789 796.
5. Dahlin, C., Linde, A., Gottlow, J. Nyman, S. (1988) Healing of bone defects by guided tissue regeneration. Plastic and Reconstructive Surgery 81, 672 676.
6. Dahlin, C., Sennerby, L., Lekholm, U., Linde, A. Nyman, S. (1989) Generation of new bone around titanium implants using a membrane technique: an experimental study in rabbits. International Journal of Oral and Maxillofacial Implants 4, 19 25.
7. Donath, K. (1985) The diagnostic value of the new method for the study of undecalcified bones and teeth with attached soft tissue (Säge-Schliff (sawing and grinding) technique). Pathology Research and Practice 179, 631 633.
8. Draper, H. H. (1994) Bone loss in animals. In : Draper, H. H. (ed). Advances in Nutritional Research, Vol. 9, pp. 53 71. New York : Plenum Press.
9. Ferguson, S. J., Broggini, N., Wieland, M., de Wild, M., Rupp, F., Geis-Gerstorfer, J., Cochran, D. L. Buser, D. (2006) Biomechanical evaluation of the interfacial strength of a chemically modified sandblasted and acid-etched titanium surface. Journal of Biomedical Materials Research A 78, 291 297.
10. Gallop, P. M., Lian, J. B. Hauschka, P. V. (1980) Carboxylated calcium-binding proteins and vitamin K. New England Journal of Medicine 302, 1460 1466.
11. Hauschka, P. V., Lian, J. B., Cole, D. E. Gundberg, C. M. (1989) Osteocalcin and matrix Gla protein: vitamin K-dependent proteins in bone. Physiological Reviews 69, 990 1047.
12. Hopyan, S., Gokgoz, N., Bell, R. S., Andrulis, I. L., Alman, B. A. Wunder, J. S. (1999) Expression of osteocalcin and its transcriptional regulators core-binding factor alpha 1 and MSX2 in osteoid-forming tumours. Journal of Orthopaedic Research 17, 633 638.
13. Liu, H. M., Wang, D. L. Liu, C. Y. (1990) Interactions between fibrin, collagen and endothelial cells in angiogenesis. Advances in Experimental Medicine and Biology 281, 319 331.
14. Long, M. W., Robinson, J. A., Ashcraft, E. A. Mann, K. G. (1995) Regulation of human bone marrow-derived osteoprogenitor cells by osteogenic growth factors. Journal of Clinical Investigation 95, 881 887.
15. Mayfield, L., Skoglund, A., Nobreus, N. Attstrom, R. (1998) Clinical and radiographic evaluation, following delivery of fixed reconstructions, at GBR treated titanium fixtures. Clinical Oral Implants Research 9, 292 302.
16. Oh, T. J., Meraw, S. J., Lee, E. J., Giannobile, W. V. Wang, H. L. (2003) Comparative analysis of collagen membranes for the treatment of implant dehiscence defects. Clinical Oral Implants Research 14, 80 90.
17. Polimeni, G., Koo, K. T., Qahash, M., Xiropaidis, A. V., Albandar, J. M. Wikesjö, U. M. (2004) Prognostic factors for alveolar regeneration: bone formation at teeth and titanium implants. Journal of Clinical Periodontology 31, 927 932.
18. Raymond, M. H., Schutte, B. C., Torner, J. C., Burns, T. L. Willing, M. C. (1999) Osteocalcin: genetic and physical mapping of the human gene BGLAP and its potential role in postmenopausal osteoporosis. Genomics 60, 210 217.
19. Reilly, T. M., Seldes, R., Luchetti, W. Brighton, C. T. (1998) Similarities in the phenotypic expression of pericytes and bone cells. Clinical Orthopaedics and Related Research 346, 95 103.
20. Rickard, D. J., Kassem, M., Hefferan, T. E., Sarkar, G., Spelsberg, T. C. Riggs, B. L. (1996) Isolation and characterization of osteoblast precursor cells from human bone marrow. Journal of Bone and Mineral Research 11, 312 324.
21. Rupp, F., Scheideler, L., Olshanska, N., de Wild, M., Wieland, M. Geis-Gerstorfer, J. (2006) Enhancing surface free energy and hydrophilicity through chemical modification of microstructured titanium implant surfaces. Journal of Biomedical Materials Research A 76, 323 334.
22. Schenk, R. K., Olah, A. J. Herrmann, W. (1984) Preparation of calcified tissues for light microscopy. In : Dickson, G. R. (ed). Methods of Calcified Tissue Preparation, pp. 1 56. Amsterdam : Elsevier.
23. Schwarz, F., Ferrari, D., Herten, M., Mihatovic, I., Wieland, M., Sager, M. Becker, J. (2007a) Effects of surface hydrophilicity and microtopography on early stages of soft and hard tissue integration at nonsubmerged titanium implants. An immunohistochemical study in dogs. Journal of Periodontology 78, 2171 2184.
24. ® Collagen). An immunohistochemical study in dogs. International Journal of Oral and Maxillofacial Implants, doi :.
25. Schwarz, F., Herten, M., Sager, M., Wieland, M., Dard, M. Becker, J. (2007c) Bone regeneration in dehiscence-type defects at chemically modified (SLActive) and conventional SLA titanium implants: a pilot study in dogs. Journal of Clinical Periodontology 34, 78 86.
26. ® titanium implants: preliminary results of a pilot study in dogs. Clinical Oral Implants Research 18, 481 488.
27. Schwarz, F., Rothamel, D., Herten, M., Sager, M., Ferrari, D. Becker, J. (2007e) Immunohistochemical characterization of guided bone regeneration at dehiscence-type defect using different barrier membranes. An experimental study in dogs. Clinical Oral Implants Research (in press).
28. Stavropoulos, A., Kostopoulos, L., Mardas, N., Nyengaard, J. R. Karring, T. (2001) Deproteinized bovine bone used as an adjunct to guided bone augmentation: an experimental study in the rat. Clinical Implant Dentistry and Related Research 3, 156 165.
29. Trombelli, L., Lee, M. B., Promsudthi, A., Guglielmoni, P. G. Wikesjö, U. M. (1999) Periodontal repair in dogs: histologic observations of guided tissue regeneration with a prostaglandin E1 analog/methacrylate composite. Journal of Clinical Periodontology 26, 381 387.
30. Zablotsky, M., Meffert, R., Caudill, R. Evans, G. (1991) Histological and clinical comparisons of guided tissue regeneration on dehisced hydroxylapatite-coated and titanium endosseous implant surfaces: a pilot study. International Journal of Oral and Maxillofacial Implants 6, 294 303.
31. Zhao, G., Raines, A. L., Wieland, M., Schwartz, Z. Boyan, B. D. (2007) Requirement for both micron- and submicron scale structure for synergistic responses of osteoblasts to substrate surface energy and topography. Biomaterials 28, 2821 2829.
32. Zhao, G., Schwartz, Z., Wieland, M., Rupp, F., Geis-Gerstorfer, J., Cochran, D. L. Boyan, B. D. (2005) High surface energy enhances cell response to titanium substrate microstructure. Journal of Biomedical Materials Research A 74, 49 58.