Synthesis, antimicrobial and antineoplastic activities for agelasine and agelasimine analogs with a β-cyclocitral derived substituent

Archiv der Pharmazie

Volumn 340, Issue 12, 2007, Pages 625-634

  Proszenyák, Agnes ^a   Charnock, Colin ^b   Hedner, Erik ^c   Larsson, Rolf ^d   Bohlin, Lars ^c   Gundersen, Lise Lotte ^a  

^a UNIVERSITY OF OSLO   (Norway)

^b OSLO METROPOLITAN UNIVERSITY   (Norway)

^c UPPSALA UNIVERSITY   (Sweden)

^d UPPSALA UNIVERSITY HOSPITAL   (Sweden)

Author keywords

Cyclocitral; Agelasimine; Agelasine; Anti cancer activity; Antimicrobial activity

Indexed keywords

6 AMINO 9 METHYL 7 [3,7 DIMETHYL 9 (2,6,6 TRIMETHYLCYCLOHEX 1 ENYL)NONA 2,6 DIEN 1 YL] 7H PURINIUM CHLORIDE; 7 [3,7 DIMETHYL 9 (2,6,6 TRIMETHYLCYCLOHEX 1 ENYL)NONA 2,6 DEINYL] 3 METHYL 2,3 DIHYDRO 1H PURIN 6(7H)IMINE; 7 [3,7 DIMETHYL 9 (2,6,6 TRIMETHYLCYCLOHEX 1 ENYL)NONA 2,6 DIENYL] 3 METHYL 3H PURIN 6(7H)IMINE; [3,7 DIMETHYL 9 (2,6,6 TRIMETHYLCYCLOHEX 1 ENYL)NONA 2,6 DEIN 1 YL] 6 BENZYLOXYAMINO 9 METHYL 7H PURINIUM; [3,7 DIMETHYL 9 (2,6,6 TRIMETHYLCYCLOHEX 1 ENYL)NONA 2,6 DEIN 1 YL] 6 METHOXYAMINO 9 METHYL 7H PURINIUM; [3,7 DIMETHYL 9 (2,6,6 TRIMETHYLCYCLOHEX 1 ENYL)NONA 2,6 DEIN 1 YL]TERT BUTOXYAMINO 9 METHYL 7H PURINIUM; AGALASINE D; AGALASINE E; AGALASINE F; AGELASIMINE A; AGELASIMINE B; AGELASIMINE DERIVATIVE; AGELASINE DERIVATIVE; ANTIINFECTIVE AGENT; ANTINEOPLASTIC AGENT; BENZALKONIUM CHLORIDE; CITRAL; DOXORUBICIN; GENTAMICIN; N [7 [3,7 DIMETHYL 9 (2,6,6 TRIMETHYLCYCLOHEX 1 ENYL)NONA 2,6 DIENYL] 3 METHYL 3H PURIN 6(7H)YLIDENE]METHANAMINE; RIFAMPICIN; UNCLASSIFIED DRUG;

ACANTHAMOEBA; ACANTHAMOEBA CASTELLANII; ACANTHAMOEBA KERATITIS; ACANTHAMOEBA POLYPHAGA; ANTIBACTERIAL ACTIVITY; ANTIMICROBIAL ACTIVITY; ANTINEOPLASTIC ACTIVITY; ANTIPROTOZOAL ACTIVITY; ARTICLE; BIOLOGICAL ACTIVITY; CANCER CELL CULTURE; CONCENTRATION RESPONSE; CONTACT LENS; CONTROLLED STUDY; DRUG CYTOTOXICITY; DRUG EFFICACY; DRUG STABILITY; DRUG SYNTHESIS; ESCHERICHIA COLI; HUMAN; HUMAN CELL; IC 50; MICROTITER PLATE ASSAY; MINIMUM INHIBITORY CONCENTRATION; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; PRIORITY JOURNAL; STAPHYLOCOCCUS AUREUS;

ACANTHAMOEBA; ADENINE; AGELAS; ALDEHYDES; ANIMALS; ANTI-BACTERIAL AGENTS; ANTINEOPLASTIC AGENTS; ANTIPARASITIC AGENTS; CELL LINE, TUMOR; DITERPENES; DRUG SCREENING ASSAYS, ANTITUMOR; ESCHERICHIA COLI; GUANIDINES; HUMANS; MICROBIAL SENSITIVITY TESTS; MYCOBACTERIUM TUBERCULOSIS; NAPHTHOLS; PURINES; STAPHYLOCOCCUS AUREUS; STEREOISOMERISM; STRUCTURE-ACTIVITY RELATIONSHIP; TERPENES;

EID: 37349042883     PISSN: 03656233     EISSN: 15214184     Source Type: Journal    
DOI: 10.1002/ardp.200700137     Document Type: Article

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