Autosomal dominant psychiatric disorders and mitochondrial DNA multiple deletions: Report of a family

Journal of Affective Disorders

Volumn 106, Issue 1-2, 2008, Pages 173-177

  Mancuso, Michelangelo ^a   Ricci, Giulia ^a   Choub, Anna ^a   Filosto, Massimiliano ^b   DiMauro, Salvatore ^c   Davidzon, Guido ^c   Tessa, Alessandra ^d   Santorelli, Filippo M ^d   Murri, Luigi ^a   Siciliano, Gabriele ^a  

^a UNIVERSITY OF PISA   (Italy)

^b UNIVERSITY OF BRESCIA   (Italy)

^c NewYork Presbyterian Hospital   (United States)

^d BAMBINO GESÙ CHILDREN S HOSPITAL   (Italy)

Author keywords

Bipolar disorder; Mitochondrial disease; mtDNA; Psychiatric symptoms; Schizophrenia

Indexed keywords

MITOCHONDRIAL DNA;

ADULT; ARTICLE; AUTOSOMAL DOMINANT DISORDER; BIPOLAR DISORDER; CASE REPORT; DEPRESSION; FAMILY; FEMALE; HUMAN; ITALY; MITOCHONDRIAL DNA DEPLETION; PRIORITY JOURNAL; RECURRENT DISEASE; SCHIZOPHRENIA;

BIOPSY; BIPOLAR DISORDER; CHROMOSOME ABERRATIONS; CHROMOSOME DELETION; DEPRESSIVE DISORDER, MAJOR; DIAGNOSIS, DIFFERENTIAL; DNA, MITOCHONDRIAL; FEMALE; GENES, DOMINANT; HUMANS; MIDDLE AGED; MITOCHONDRIA, MUSCLE; MITOCHONDRIAL ENCEPHALOMYOPATHIES; PEDIGREE; POLYMERASE CHAIN REACTION; RECURRENCE; SCHIZOPHRENIA;

EID: 37349031029     PISSN: 01650327     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jad.2007.05.016     Document Type: Article

References (18)

1. Ben-Shachar D., and Laifenfeld D. Mitochondria, synaptic plasticity, and schizophrenia. Int. Rev. Neurobiol. 59 (2004) 273-296
2. DiMauro S., and Schon E.A. Mitochondrial respiratory-chain diseases. N. Engl. J. Med. 348 (2003) 2656-2668
3. Filosto M., Mancuso M., Nishigaki Y., Pancrudo J., Harati Y., Gooch C., Mankodi A., Bayne L., Bonilla E., Shanske S., Hirano M., and DiMauro S. Progressive external ophthalmoplegia due to mutations in polymerase gamma (POLG): clinical and genetic heterogeneity. Arch. Neurol. 60 (2003) 1279-1284
4. Gershon E.S. Genetics. In: Goodwin F.K., and Jamison K.R. (Eds). Manic-Depressive Illness (1990), Oxford University Press, Oxford 373-401
5. Inagaki T., Ishino H., Seno H., Ohguni S., Tanaka J., and Kato Y. Psychiatric symptoms in a patient with diabetes mellitus associated with point mutation in mitochondrial DNA. Biol. Psychiatry 42 (1997) 1067-1069
6. Kato T., Inubushi T., and Kato N. Magnetic resonance spectroscopy in affective disorders. J Neuropsychiatry Clin. Neurosci. 10 (1998) 133-147
7. Kato T., and Kato N. Mitochondrial dysfunction in bipolar disorder. Bipolar Disord. 2 (2000) 180-190
8. Kato T., Kunugi H., Nanko S., and Kato N. Mitochondrial DNA polymorphisms in bipolar disorder. J. Affect. Disord. 62 (2001) 151-164
9. Kato T., Stine O.C., McMahon F.J., and Crowe R.R. Increased levels of a mitochondrial DNA deletion in the brain of patients with bipolar disorder. Biol. Psychiatry 42 (1997) 871-875
10. Kirk R., Furlong R.A., Amos W., Cooper G., Rubinsztein J.S., Walsh C., Paykel E.S., and Rubinsztein D.C. Mitochondrial genetic analyses suggest selection against maternal lineages in bipolar affective disorder. Am. J. Hum. Genet. 65 (1999) 508-518
11. Koller H., Kornischka J., Neuen-Jacob E., Saleh A., von Giesen H.J., Schmiedel J., Reichmann H., and Hartung H.P. Persistent organic personality change as rare psychiatric manifestation of MELAS syndrome. J. Neurol. 250 (2003) 1501-1502
12. Lewis C.M., Levinson D.F., Wise L.H., DeLisi L.E., Straub R.E., Hovatta I., Williams N.M., Schwab S.G., Pulver A.E., Faraone S.V., Brzustowicz L.M., Kaufmann C.A., Garver D.L., Gurling H.M., Lindholm E., Coon H., Moises H.W., Byerley W., Shaw S.H., Mesen A., Sherrington R., O'Neill F.A., Walsh D., Kendler K.S., Ekelund J., Paunio T., Lonnqvist J., Peltonen L., O'Donovan M.C., Owen M.J., Wildenauer D.B., Maier W., Nestadt G., Blouin J.L., Antonarakis S.E., Mowry B.J., Silverman J.M., Crowe R.R., Cloninger C.R., Tsuang M.T., Malaspina D., Harkavy-Friedman J.M., Svrakic D.M., Bassett A.S., Holcomb J., Kalsi G., McQuillin A., Brynjolfson J., Sigmundsson T., Petursson H., Jazin E., Zoega T., and Helgason T. Genome scan meta-analysis of schizophrenia and bipolar disorder, part II: schizophrenia. Am. J. Hum. Genet. 73 (2003) 34-48
13. Mancuso M., Filosto M., Bellan M., Liguori R., Montagna P., Baruzzi A., DiMauro S., and Carelli V. POLG mutations causing ophthalmoplegia, sensorimotor polyneuropathy, ataxia, and deafness. Neurology. 62 (2004) 316-318
14. Mancuso M., Filosto M., Mootha V.K., Rocchi A., Pistolesi S., Murri L., DiMauro S., and Siciliano G. A novel mitochondrial tRNAPhe mutation causes MERRF syndrome. Neurology. 62 (2004) 2119-2121
15. McMahon F.J., Stine O.C., Meyers D.A., Simpson S.A., and DePaulo J.R. Patterns of maternal transmission in bipolar affective disorder. Am. J. Hum. Genet. 56 (1995) 1277-1286
16. Siciliano G., Tessa A., Petrini S., Mancuso M., Bruno C., Grieco G.S., Malandrini A., DeFlorio L., Martini B., Federico A., Nappi G., Santorelli F.M., and Murri L. Autosomal dominant external ophthalmoplegia and bipolar affective disorder associated with a mutation in the ANT1 gene. Neuromuscul. Disord. 13 (2003) 162-165
17. Suomalainen A., Majander A., Wallin M., Setala K., Kontula K., Leinonen H., Salmi T., Paetau A., Hatia M., Valanne L., Peltonen L., and Somer H. Autosomal dominant progressive external ophthalmoplegia with multiple deletions of mtDNA: clinical, biochemical, and molecular genetic features of the 10q-linked disease. Neurology. 48 (1997) 1244-1253
18. Thomeer E.C., Verhoeven W.M., van de Vlasakker C.J., and Klompenhouwer J.L. Psychiatric symptoms in MELAS; a case report. J Neurol Neurosurg Psychiatry. 64 (1998) 692-693