Adiponectin: Is it a novel treatment modality to alleviate liver injury in non-alcoholic fatty liver disease (NAFLD)?

Medical Hypotheses

Volumn 70, Issue 2, 2008, Pages 457-458

  Aygun, Cem ^a   Kocaman, Orhan ^a   Senturk, Omer ^a  

^a KOCAELI UNIVERSITY   (Turkey)

Author keywords

[No Author keywords available]

Indexed keywords

ADIPONECTIN; INSULIN;

DRUG MECHANISM; FIBROSIS; HUMAN; INSULIN BLOOD LEVEL; INSULIN SENSITIVITY; LETTER; LIFESTYLE MODIFICATION; LIVER FUNCTION; LIVER HISTOLOGY; LIVER INJURY; NONALCOHOLIC FATTY LIVER; PRIORITY JOURNAL; PROTEIN ISOLATION;

ADIPONECTIN; ANIMALS; FATTY ACIDS; FATTY LIVER; HUMANS; LIVER; MICE; MODELS, BIOLOGICAL; RECOMBINANT PROTEINS; TUMOR NECROSIS FACTOR-ALPHA;

EID: 37349007791     PISSN: 03069877     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mehy.2007.05.034     Document Type: Letter

References (5)

1. Yokota T., Oritani K., Takahashi I., Ishikawa J., Matsuyama A., Ouchi N., et al. Adiponectin, a new member of the family of soluble defense collagens, negatively regulates the growth of myelomonocytic progenitors and the functions of macrophages. Blood 96 (2000) 1723-1732
2. Aygun C., Senturk O., Hulagu S., Uraz S., Celebi A., Konduk T., et al. Serum levels of hepatoprotective peptide adiponectin in non-alcoholic fatty liver disease. Eur J Gastroen Hepat 18 (2006) 175-180
3. Fruebis J., Tsao T.S., Javorschi S., Ebbets-Reed D., Erickson M.R., Yen F.T., et al. Proteolytic cleavage product of 30-kDa adipocyte complement-related protein increases fatty acid oxidation in muscle and causes weight loss in mice. Proc Natl Acad Sci USA 98 (2001) 2005-2010
4. Ouchi N., Kihara S., Arita Y., Maeda K., Kuriyama H., Okamoto Y., et al. Novel modulator for endothelial adhesion molecules: adipocyte-derived plasma protein adiponectin. Circulation 100 (1999) 2473-2476
5. Maeda N., Takahashi M., Funahashi T., Kihara S., Nishizawa H., Kishida K., et al. PPARγ ligands increase expression and plasma concentrations of adiponectin, an adipose-derived protein. Diabetes 50 (2001) 2094-2099