Mechanistic QSAR of aromatic amines: New models for discriminating between homocyclic mutagens and nonmutagens, and validation of models for carcinogens

Environmental and Molecular Mutagenesis

Volumn 48, Issue 9, 2007, Pages 754-771

  Benigni, Romualdo ^a   Bossa, Cecilia ^a   Netzeva, Tatiana ^b   Rodomonte, Andrea ^a   Tsakovska, Ivanka ^b  

^a ISTITUTO SUPERIORE DI SANITÀ   (Italy)

^b JOINT RESEARCH CENTRE   (Italy)

Author keywords

Aromatic amines; Cancer; Genotoxicity; In silico; Risk assessment; Structure activity

Indexed keywords

1 AMINO 2 METHYLNAPHTHALENE; 1 AMINOANTHRACENE; 1 AMINOCARBAZOLE; 1 AMINOFLUORANTHENE; 1 AMINOFLUORENE; 1 AMINOPHENANTHRENE; 1 AMINOPHENAZINE; 1 AMINOPYRENE; 1 NAPHTHYLAMINE; 1,7 DIAMINOPHENAZINE; 1,9 DIAMINOPHENAZINE; 2 AMINO 1 METHYLNAPHTHALENE; 2,2' DIAMINOBIPHENYL; 2,3 DIMETHYLANILINE; 2,4 DIAMINO N BUTYLBENZENE; 2,4 DIFLUOROANILINE; 2,4 DIMETHYLANILINE; 2,4 DINITROANILINE; 2,4' DIAMINODIPHENYL; 2,4,5 TRIMETHYLANILINE; 2,5 DIMETHYLANILINE; 2,6 CHLORO 1,4 PHENYLENEDIAMINE; 2,7 DIAMINOFLUORENE; 2,7 DIAMINOPHENAZINE; 4 ISOPROPYL 1,3 BENZENEDIAMINE; 4 NITRO 1 NAPHTHYLAMINE; AROMATIC AMINE; CARCINOGEN; MUTAGENIC AGENT; UNCLASSIFIED DRUG; UNINDEXED DRUG;

ARTICLE; BACTERIAL STRAIN; CARCINOGENESIS; CARCINOGENICITY; GENE MUTATION; MODEL; MUTAGENICITY; NONHUMAN; QUANTITATIVE STRUCTURE ACTIVITY RELATION; RISK ASSESSMENT; RODENT; SALMONELLA TYPHIMURIUM; VALIDATION PROCESS;

AMINES; CARCINOGENS; MODELS, CHEMICAL; MUTAGENS; QUANTITATIVE STRUCTURE-ACTIVITY RELATIONSHIP; SALMONELLA TYPHIMURIUM;

RODENTIA; SALMONELLA TYPHIMURIUM;

EID: 37349002009     PISSN: 08936692     EISSN: 10982280     Source Type: Journal    
DOI: 10.1002/em.20355     Document Type: Article

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