Effect of maternal administration of betamethasone on peripheral arterial development in fetal rabbit lungs

Neonatology

Volumn 93, Issue 1, 2007, Pages 64-72

  Roubliova, Xenia I ^a   Van Der Biest, AnneMarie ^a   Vaast, Pascal ^c   Lu, HuiQi ^a   Jani, Jacques ^a,b   Lewi, Paul J ^a,b   Verbeken, Eric K ^b   Tibboel, Dick ^d   Deprest, Jan A ^a,b,e  

^a Center for Surgical Technologies Leuven   (Belgium)

^b UNIVERSITY HOSPITALS LEUVEN   (Belgium)

^c LILLE UNIVERSITY HOSPITAL   (France)

^d SOPHIA CHILDREN S HOSPITAL   (Netherlands)

^e Center for Surgical Technologies   (Belgium)

Author keywords

Alveolar epithelial cells, Flk 1 positive; Betamethasone, antenatal; Lung, fetal rabbit; Vascularization, lung

Indexed keywords

ALPHA SMOOTH MUSCLE ACTIN; BETAMETHASONE; ENDOTHELIAL NITRIC OXIDE SYNTHASE; SODIUM CHLORIDE; VASCULOTROPIN; VASCULOTROPIN RECEPTOR 2;

ANALYSIS OF VARIANCE; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTERY; ARTERY ADVENTITIA; ARTERY DIAMETER; ARTERY MEDIA; ARTICLE; BODY WEIGHT; CELL DENSITY; CONTROLLED STUDY; DEVELOPMENT; ENDOTHELIUM CELL; EPITHELIUM CELL; FETUS; FETUS WEIGHT; GESTATIONAL AGE; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; LUNG; LUNG BLOOD VESSEL; LUNG WEIGHT; MORPHOMETRICS; NONHUMAN; PREGNANCY; PRIORITY JOURNAL; PULMONARY ARTERY; RABBIT; SMOOTH MUSCLE FIBER; STUDENT T TEST;

ANIMALS; ARTERIOLES; BETAMETHASONE; FEMALE; FETAL DEVELOPMENT; GESTATIONAL AGE; GLUCOCORTICOIDS; LUNG; MUSCLE, SMOOTH, VASCULAR; PREGNANCY; RABBITS; VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR-2;

ORYCTOLAGUS CUNICULUS;

EID: 37249089654     PISSN: 16617800     EISSN: 16617819     Source Type: Journal    
DOI: 10.1159/000107231     Document Type: Article

References (37)

1. Haworth SG: Pulmonary arterial remodelling in the developing lung. Eur Respir Rev 1993;16:550-554.
2. Bolt RJ, van Weissenbruch MM, Lafeber HN, Delemarre-van de Waal HA: Glucocorticoids and lung development in the fetus and preterm infant. Pediatr Pulmonol 2001;32:76-91.
3. Tabor BL, Rider ED, Ikegami M, Jobe AH, Lewis JF: Dose effects of antenatal corticosteroids for induction of lung maturation in preterm rabbits. Am J Obstet Gynecol 1991;164:675-681.
4. Antenatal corticosteroids revisited: repeat courses. NIH Consens Statement 2000;17:1-18.
5. Newnham JP, Moss TJ: Antenatal glucocorticoids and growth: single versus multiple doses in animal and human studies. Semin Neonatol 2001;6:285-292.
6. Wu J, Yamamoto H, Gratacos E, Ge X, Verbeken E, Sueishi K, Hashimoto S, Vanamo K, Lerut T, Deprest J: Lung development following diaphragmatic hernia in the fetal rabbit. Hum Reprod 2000;15:2483-2488.
7. Roubliova XI, Verbeken EK, Wu J, Vaast P, Jani J, Deprest JA: Effect of tracheal occlusion on peripheric pulmonary vessel muscularization in a fetal rabbit model for congenital diaphragmatic hernia. Am J Obstet Gynecol 2004;191:830-836.
8. Pringle KC: Human fetal lung development and related animal models. Clin Obstet Gynecol 1986;29:502-513.
9. Frelin C, Ladoux A, D'Angelo G: Vascular endothelial growth factors and angiogenesis. Ann Endocrinol (Paris) 2000;61:70-74.
10. Brown KR, England KM, Goss KL, Snyder JM, Acarregui MJ: VEGF induces airway epithelial cell proliferation in human fetal lung in vitro. Am J Physiol Lung Cell Mol Physiol 2001;281:L1001-L1010.
11. de Vries C, Escobedo JA, Ueno H, Houck K, Ferrara N, Williams LT: The fms-like tyrosine kinase, a receptor for vascular endothelial growth factor. Science 1992;255:989-991.
12. Shen BQ, Lee DY, Zioncheck TF: Vascular endothelial growth factor governs endothelial nitric-oxide synthase expression via a KDR/Flk-1 receptor and a protein kinase C signaling pathway. J Biol Chem 1999;274:33057-33063.
13. Lin CH, Tsai ML, Chou SJ, Yeh TF: Effect of antenatal dexamethasone on the expression of endothelial nitric oxide synthase in the lungs of postnatal pups. Semin Perinatol 2001;25:94-99.
14. Pross C, Farooq MM, Lane JS, Cerveira JJ, Xavier AE, Freischlag JA, Law RE, Gelabert HA: Rat and human aortic smooth muscle cells display differing migration and matrix metalloproteinase activities in response to dexamethasone. J Vasc Surg 2002;35:1253-1259.
15. Gundersen HJ, Bendtsen TF, Korbo L, Marcussen N, Moller A, Nielsen K,Nyengaard JR, Pakkenberg B, Sorensen FB, Vesterby A: Some new, simple and efficient stereological methods and their use in pathological research and diagnosis. APMIS 1988;96:379-394.
16. Davies P: Morphologic and morphometric techniques for the detection of drug- and toxin-induced changes in lung. Pharmacol Ther 1991;50:321-336.
17. Kay JM: Comparative morphologic features of the pulmonary vasculature in mammals. Am Rev Respir Dis 1983;128:S53-S57.
18. Kanai M, Kitano Y, von Allmen D, Davies P, Adzick NS, Flake AW: Fetal tracheal occlusion in the rat model of nitrofen-induced congenital diaphragmatic hernia: tracheal occlusion reverses the arterial structural abnormality. J Pediatr Surg 2001;36:839-845.
19. Luks FI, Wild YK, Piasecki GJ, De Paepe ME: Short-term tracheal occlusion corrects pulmonary vascular anomalies in the fetal lamb with diaphragmatic hernia. Surgery 2000;128:266-272.
20. Giaid A, Stewart DJ, Michel RP: Endothelin-1-like immunoreactivity in postobstructive pulmonary vasculopathy. J Vasc Res 1993;30:333-338.
21. Shehata SM, Sharma HS, Mooi WJ, Tibboel D: Pulmonary hypertension in human newborns with congenital diaphragmatic hernia is associated with decreased vascular expression of nitric-oxide synthase. Cell Biochem Biophys 2006;44:147-155.
22. French NP, Hagan R, Evans SF: Repeated antenatal corticosteroids: size at birth and subsequent development. Am J Obstet Gynecol 1999;180:114-121.
23. Ain R, Canham LN, Soares MJ: Dexamethasone-induced intrauterine growth restriction impacts the placental prolactin family, insulin-like growth factor-II and the Akt signaling pathway. Endocrinology 2005;185:253-263.
24. Ikegami M, Jobe AH, Newnham J, Polk DH, Willet KE, Sly P: Repetitive prenatal glucocorticoids improve lung function and decrease growth in preterm lambs. Am J Respir Crit Care Med 1997;156:178-184.
25. Venkatesh VC, Katzberg HD: Glucocorticoid regulation of epithelial sodium channel genes in human fetal lung. Am J Physiol 1997;273:L227-L233.
26. Emery CJ: Vascular remodelling in the lung. Eur Respir J 1994;7:217-219.
27. Moise AA, Wearden ME, Kozinetz CA, Gest AL, Welty SE, Hansen TN: Antenatal steroids are associated with less need for blood pressure support in extremely premature infants. Pediatrics 1995;95:845-850.
28. Hall SM, Hislop AA, Pierce CM, Haworth SG: Prenatal origins of human intrapulmonary arteries: formation and smooth muscle maturation. Am J Respir Cell Mol Biol 2000;23:194-203.
29. Okoye BO, Losty PD, Lloyd DA, Gosney JR: Effect of prenatal corticosteroids on pulmonary vascular muscularisation in nitrofeninduced congenital diaphragmatic hernia. J Pediatr Surg 1998;1:76-80.
30. Brenner RE, Felger D, Winter C: Effects of dexamethasone on proliferation, chemotaxis, collagen I, and fibronectin-metabolism of human fetal lung fibroblasts. Pediatr Pulmonol 2001;32:1-7.
31. Stewart AG, Fernandes D, Tomlinson PR: The effect of glucocorticoids on proliferation of human cultured airway smooth muscle. Br J Pharmacol 1995;116:3219-3226.
32. Reil TD, Sarkar R, Kashyap VS, Sarkar M, Gelabert HA: Dexamethasone suppresses vascular smooth muscle cell proliferation. J Surg Res 1999;85:109-114.
33. van der Zee R, Murohara T, Luo Z, Zollmann F, Passeri J, Lekutat C, Isner JM: Vascular endothelial growth factor/vascular permeability factor augments nitric oxide release from quiescent rabbit and human vascular endothelium. Circulation 1997;95:1030-1037.
34. Hood JD, Meininger CJ, Ziche M, Granger HJ: VEGF upregulates ecNOS message, protein, and NO production in human endothelial cells. Am J Physiol 1998;274:H1054-H1058.
35. Grover TR, Parker TA, Zenge JP, Markham NE, Kinsella JP, Abman SH: Intrauterine hypertension decreases lung VEGF expression and VEGF inhibition causes pulmonary hypertension in the ovine fetus. Am J Physiol Lung Cell Mol Physiol 2003;284:L508-L517.
36. Shehata SM, Sharma HS, van der Staak FH, van de Kaa-Hulsbergen C, Mooi WJ, Tibboel D: Remodeling of pulmonary arteries in human congenital diaphragmatic hernia with or without extracorporeal membrane oxygenation. J Pediatr Surg 2000;35:208-215.
37. Mustafa SB, DiGeronimo RJ, Petershack JA, Alcorn JL, Seidner SR: Postnatal glucocorticoids induce alpha-ENaC formation and regulate glucocorticoid receptors in the preterm rabbit lung. Am J Physiol Lung Cell Mol Physiol 2004;286:L73-L80.