Randomized clinical trial of moxonidine in patients undergoing major vascular surgery

British Journal of Surgery

Volumn 94, Issue 12, 2007, Pages 1477-1484

  Bolliger, D ^a   Seeberger, M D ^a   Lurati Buse, G A L ^a   Christen, P ^b   Gurke, L ^a   Filipovic, M ^a  

^a UNIVERSITY HOSPITAL BASEL   (Switzerland)

^b Kantonsspital Lucerne ^*  (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

MOXONIDINE; PLACEBO; TROPONIN I;

AGED; ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DRUG EFFECT; FATIGUE; FEMALE; HEART MUSCLE ISCHEMIA; HOLTER MONITORING; HUMAN; INCIDENCE; INTERVIEW; MAJOR CLINICAL STUDY; MALE; MORTALITY; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; SLEEP DISORDER; ST SEGMENT; VASCULAR SURGERY; XEROSTOMIA;

AGED; CORONARY ARTERY DISEASE; DOUBLE-BLIND METHOD; FEMALE; HEMODYNAMICS; HOSPITALIZATION; HUMANS; IMIDAZOLES; INTRAOPERATIVE COMPLICATIONS; MALE; MYOCARDIAL ISCHEMIA; POSTOPERATIVE CARE; PREOPERATIVE CARE; SYMPATHOLYTICS; TROPONIN; VASCULAR SURGICAL PROCEDURES;

EID: 37249053478     PISSN: 00071323     EISSN: 13652168     Source Type: Journal    
DOI: 10.1002/bjs.6012     Document Type: Article

References (25)

1. Bartels C, Bechtel JF, Hossmann V, Horsch S. Cardiac risk stratification for high-risk vascular surgery. Circulation 1997; 95: 2473-2475.
2. Eagle KA, Berger PB, Calkins H, Chairman BR, Ewy GA, Fleischmann KE et al. ACC/AHA guideline update for perioperative cardiovascular evaluation for noncardiac surgery - executive summary of a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Committee to Update the 1996 Guidelines on Perioperative Cardiovascular Evaluation for Noncardiac Surgery). Circulation 2002; 105: 1257-1267.
3. Sprung J, Abdelmalak B, Gottlieb A, Mayhew C, Hammel J, Levy PJ et al. Analysis of risk factors for myocardial infarction and cardiac mortality after major vascular surgery. Anesthesiology 2000; 93: 129-140.
4. Landesberg G, Shatz V, Akopnik I, WoLf YG, Mayer M, Berlatzky Y et al. Association of cardiac troponin, CK-MB, and postoperative myocardial ischemia with long-term survival after major vascular surgery. J Am Coll Cardiol 2001; 42: 1547-1554.
5. Mangano DT, Browner WS, Hollenberg M, London MJ, Tubau JF, Tateo IM. Association of perioperative myocardial ischemia with cardiac morbidity and mortality in men undergoing noncardiac surgery. The Study of Perioperative Ischemia Research Group. N Engl J Med 1990; 323: 1781-1788.
6. McFalls EO, Ward HB, Moritz TE, Goldman S, Krupski WC, Littooy F et al. Coronary-artery revascularization before elective major vascular surgery. N Engl J Med 2004; 351: 2795-2804.
7. Eagle KA, Rihal CS, Mickel MC, Holmes DR, Foster ED, Gersh BJ. Cardiac risk of noncardiac surgery: influence of coronary disease and type of surgery in 3368 operations. CASS Investigators and University of Michigan Heart Care Program. Coronary Artery Surgery Study. Circulation 1997; 96: 1882-1887.
8. Landesberg G, Luria MH, Cotev S, Eidelman LA, Anner H, Mosseri M et al. Importance of long-duration postoperative ST-segment depression in cardiac morbidity after vascular surgery. Lancet 1993; 341: 715-719.
9. Mangano DT, Layug EL, Wallace A, Tateo I. Effect of atenolol on mortality and cardiovascular morbidity after noncardiac surgery. Multicenter Study of Perioperative Ischemia Research Group. N Engl J Med 1996; 335: 1713-1720.
10. Poldermans D, Boersma E, Bax JJ, Thomson IR, van de Ven LL, Blankensteijn JD et al. The effect of bisoprolol on perioperative mortality and myocardial infarction in high-risk patients undergoing vascular surgery. Dutch Echocardiographic Cardiac Risk Evaluation Applying Stress Echocardiography Study Group. N Engl JMed 1999; 341: 1789-1794.
11. Brady AR, Gibbs JS, Greenhalgh RM, Powell JT, Sydes MR, POBBLE Trial Investigators. Perioperative beta-blockade (POBBLE) for patients undergoing infrarenal vascular surgery: results of a randomized double-blind controlled trial. J Vasc Surg 2005; 41: 602-609.
12. Yang H, Raymer K, Butler R, Parlow J, Roberts R. The effects of perioperative beta-blockade: results of the Metoprolol after Vascular Surgery (MaVS) study, a randomized controlled trial. Am Heart J 2006; 152: 983-990.
13. Devereaux PJ, Beattie WS, Choi PT, Badner NH, Guyatt GH, Villar JC et al. How strong is the evidence for the use of perioperative beta blockers in non-cardiac surgery? Systematic review and meta-analysis of randomised controlled trials. BMJ 2005; 331: 313-321.
14. Wiesbauer F, Schlager O, Domanovits H, Wildner B, Maurer G, Muellner M et al. Perioperative beta-blockers for preventing surgery-related mortality and morbidity: a systematic review and meta-analysis. Anesth Analg 2007; 104: 27-41.
15. Wallace AW, Galindez D, Salahieh A, Layug EL, Lazo EA, Haratonik KA et al. Effect of Clonidine on cardiovascular morbidity and mortality after noncardiac surgery. Anesthesiology 2004; 101: 284-293.
16. Nishina K, Mikawa K, Uesugi T, Obara H, Maekawa M, Kamae I et al. Efficacy of Clonidine for prevention of perioperative myocardial ischemia: a critical appraisal and meta-analysis of the literature. Anesthesiology 2002; 96: 323-329.
17. Wijeysundera DN, Naik JS, Beattie WS. Alpha-2 adrenergic agonists to prevent perioperative cardiovascular complications: a meta-analysis. Am J Med 2003; 114: 742-752.
18. Filipovic M, Jeger R, Probst C, Girard T, Pfisterer M, Gurke L et al. Heart rate variability and cardiac troponin I are incremental and independent predictors of one-year all-cause mortality after major noncardiac surgery in patients at risk of coronary artery disease. J Am Coll Cardiol 2003; 42: 1767-1776.
19. Alpert JS, Thygesen K, Antman E, Bassand JP. Myocardial infarction redefined - a consensus document of The Joint European Society of Cardiology/American College of Cardiology Committee for the redefinition of myocardial infarction. J Am Coll Cardiol 2000; 36: 959-969.
20. Wang J, Filipovic M, Rudzitis A, Michaux I, Skarvan K, Buser P et al. Transesophageal echocardiography for monitoring segmental wall motion during off-pump coronary artery bypass surgery. Anesth Analg 2004; 99: 965-973.
21. Kertai MD, Boersma E, Klein J, Van Urk H, Bax JJ, Poldermans D. Long-term prognostic value of asymptomatic cardiac troponin T elevations in patients after major vascular surgery. Eur J Vasc Endovasc Surg 2004; 28: 59-66.
22. Martinez EA, Nass CM, Jermyn RM, Rosenbaum SH, Akhtar S, Chan DW et al. Intermittent cardiac troponin-1 screening is an effective means of surveillance for a perioperative myocardial infarction. J Cardiothorac Vasc Anesth 2005; 19: 577-582.
23. Cohn JN, Pfeffer MA, Rouleau J, Sharpe N, Swedberg K, Straub M et al. Adverse mortality effect of central sympathetic inhibition with sustained-release moxonidine in patients with heart failure (MOXCON). Eur J Heart Fail 2003; 5: 659-667.
24. Kim LJ, Martinez EA, Faraday N, Dorman T, Fleisher LA, Perler BA et al. Cardiac troponin I predicts short-term mortality in vascular surgery patients. Circulation 2002; 106: 2366-2371.
25. Oscarsson A, Eintrei C, Anskar S, Engdahl O, Fagerstrom L, Blomqvist P et al. Troponin T-values provide long-term prognosis in elderly patients undergoing non-cardiac surgery. Acta Anaesthesiol Scand 2004; 48: 1071-1079.