P-glycoprotein expression is associated with sestamibi washout in primary hyperparathyroidism

British Journal of Surgery

Volumn 94, Issue 12, 2007, Pages 1491-1495

  Gupta, Y ^a   Ahmed, R ^a   Happerfield, L ^a   Pinder, S E ^a   Balan, K K ^a   Wishart, G C ^a  

^a ADDENBROOKE S HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM; GLYCOPROTEIN P; METHOXY ISOBUTYL ISONITRILE TECHNETIUM TC 99M; PARATHYROID HORMONE;

ARTICLE; CALCIUM BLOOD LEVEL; DRUG ACCUMULATION; FEMALE; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; MAJOR CLINICAL STUDY; MALE; MULTIDRUG RESISTANCE; PARATHYROID ADENOMA; PARATHYROID HORMONE BLOOD LEVEL; PARATHYROID TUMOR; PARATHYROIDECTOMY; PRIMARY HYPERPARATHYROIDISM; PRIORITY JOURNAL; PROTEIN EXPRESSION; THYROID SCINTISCANNING; TUMOR CELL; TUMOR VOLUME;

ADENOMA; ADULT; AGED; AGED, 80 AND OVER; FEMALE; HUMANS; HYPERPARATHYROIDISM, PRIMARY; IMMUNOHISTOCHEMISTRY; MALE; MIDDLE AGED; P-GLYCOPROTEIN; PARATHYROID HORMONE; PARATHYROID NEOPLASMS; RADIOPHARMACEUTICALS; TECHNETIUM TC 99M SESTAMIBI;

EID: 37249023846     PISSN: 00071323     EISSN: 13652168     Source Type: Journal    
DOI: 10.1002/bjs.5882     Document Type: Article

References (23)

1. Gurnell EM, Thomas SK, McFarlane I, Munday I, Balan KK, Berman L et al. Focused parathyroid surgery with intraoperative parathyroid hormone measurement as a day-case procedure. Br J Surg 2004; 91: 78-82.
2. O'Doherty MJ, Kettle AG. Parathyroid imaging: preoperative localization. Nucl Med Commun 2003; 24: 125-131.
3. Quiros RM, Alioto J, Wilhelm SM, Ali A, Prinz RA. An algorithm to maximise use of minimally invasive parathyroidectomy. Arch Surg 2004; 139: 501-507.
4. Udelsman R. One hundred consecutive minimally invasive parathyroid explorations. Ann Surg 2000; 232: 331-339.
5. Johnston LB, Carroll MJ, Britton KE, Lowe DG, Shand W, Besser GM et al. The accuracy of parathyroid gland localization in primary hyperparathyroidism using sestamibi radionuclide imaging. J Clin Endocrinol Metab 1996; 81: 346-352.
6. Sofferman RA, Nathan MH, Fairbank JT, Foster RS Jr, Krag DN. Preoperative technetium Tc 99m sestamibi imaging. Paving the way to minimal-access parathyroid surgery. Arch Otolaryngol Head Neck Surg 1996; 122: 369-374.
7. Leslie WD, Dupont JO, Bybel B, Riese KT. Parathyroid 99mTc-sestamibi scintigraphy: dual-tracer subtraction is superior to double-phase washout. Eur J Nucl Med Mol Imaging 2002; 29: 1566-1570.
8. Pons F, Torregrosa JV, Fuster D. Biological factors influencing parathyroid localization. Nucl Med Commun 2003; 24: 121-124.
9. Ugur O, Bozkurt MF, Hamaloglu E, Sokmensuer C, Etikan I, Ugur Y et al. Clinicopathologic and radiopharmacokinetic factors affecting gamma probe-guided parathyroidectomy. Arch Surg 2004; 139: 1175-1179.
10. Cermik TF, Puyan FO, Sezer A, Firat MF, Berkarda S. Relation between Tc-99m sestamibi uptake and biological factors in hyperparathyroidism. Ann Nucl Med 2005; 19: 387-392.
11. Mitchell BK, Cornelius EA, Zoghbi S, Murren JR, Ghoussoub R, Flynn SD et al. Mechanism of technetium 99m sestamibi parathyroid imaging and the possible role of p-glycoprotein. Surgery 1996; 120: 1039-1045.
12. Rao W, Chiu ML, Kronauge JF, Piwnica-Worms D. Expression of recombinant human multidrug resistant P-glycoprotein in insect cells confers decreased accumulation of technetium-99m-sestaMIBI. J Nucl Med 1994; 35: 510-515.
13. Hendrikse NH, Franssen EJ, van der Graaf WT, Meijer C, Piers DA, Vaalburg W et al. 99mTc-sestamibi is a substrate for P-glycoprotein and the multidrug resistance-associated protein. Br J Cancer 1998; 77: 353-358.
14. Bhatnagar A, Vezza PR, Bryan JA, Atkins FB, Ziessman HA. Technetium-99m-sestamibi parathyroid scintigraphy: effect of P-glycoprotein, histology and tumor size on detectability. J Nucl Med 1998; 39: 1617-1620.
15. Yamaguchi S, Yachiku S, Hashimoto H, Kaneko S, Nishihara M, Niibori D et al. Relation between technetium 99m-methoxyisobutylisonitrile accumulation and multidrug resistance protein in the parathyroid glands. World J Surg 2002; 26: 29-34.
16. Kao A, Shiau YC, Tsai SC, Wang JJ, Ho ST. Technetium-99m methoxyisobutylisonitrile imaging for parathyroid adenoma: relationship to P-glycoprotein or multidrug resistance-related protein expression. Eur J Nucl Med 2002; 19: 1012-1015.
17. Thomas SK, Wishart GC. Technical note. Lateral approach to parathyroid adenoma excision. Ann R Coll Engl 2004; 86: 474-475.
18. Sun SS, Shiau YC, Lin CC, Kao A, Lee CC. Correlation between P-glycoprotein (P-gp) expression in parathyroid and Tc-99m MIBI parathyroid image findings. Nucl Med Biol 2001; 28: 929-933.
19. Wu HS, Liu YC, Kao A, Wang JJ, Ho ST. Using technetium 99m tetrofosmin parathyroid imaging to detect parathyroid adenoma and its relation to P-glycoprotein expression. Surgery 2002; 132: 456-460.
20. Parikshak M, Castillo ED, Conrad MF, Talpos GB. Impact of hypercalcaemia and parathyroid hormone level on the sensitivity of preoperative sestamibi scanning for primary hyperparathyroidism. Am Surg 2003; 69: 393-399.
21. Carpentier A, Jeannotte S, Verreault J, Lefebvre B, Bisson G, Mongeau CJ et al. Preoperative localization of parathyroid lesions in hyperparathyroidism: relationship between technetium-99m-MIBI uptake and oxyphil cell content. J Nucl Med 1998; 39: 1441-1444.
22. Kabasakal L, Halac M, Nisli C, Oguz O, Onsel C, Civi G et al. The effect of P-glycoprotein inhibition with cyclosporine A on the biodistribution of Tc-99m sestamibi. Clin Nucl Med 2000; 25: 20-23.
23. Mistry P, Stewart AJ, Dangerfield W, Okiji S, Liddle C, Bootle D et al. In vitro and in vivo reversal of P-glycoprotein-mediated multidrug resistance by a novel potent modulator, XR9576. Cancer Res 2001; 61: 749-758.