Single-nucleotide polymorphisms of the cytidine deaminase gene in childhood with acute leukemia and normal Chinese children

Chinese Journal of Medical Genetics

Volumn 24, Issue 6, 2007, Pages 699-702

  Yue, Li Jie ^a   Chen, Xiao Wen ^a   Li, Cheng Rong ^a   Li, Chang Gang ^a   Shi, Hong Song ^a   Zhang, Min ^a  

^a SHENZHEN CHILDREN'S HOSPITAL   (China)

Author keywords

Acute leukemia; Coding single nucleotide polymorphism; Cytidine deaminase gene; Denaturing gradient gel electrophoresis

Indexed keywords

COMPLEMENTARY DNA; CYTARABINE; CYTIDINE DEAMINASE;

ACUTE LEUKEMIA; ALLELE; ARTICLE; BLOOD SAMPLING; CHILD; CHINESE; CONTROLLED STUDY; DENATURING GRADIENT GEL ELECTROPHORESIS; DNA DETERMINATION; GENE FREQUENCY; HUMAN; MAJOR CLINICAL STUDY; POLYMERASE CHAIN REACTION; RESTRICTION FRAGMENT LENGTH POLYMORPHISM; SINGLE NUCLEOTIDE POLYMORPHISM;

ACUTE DISEASE; ASIAN CONTINENTAL ANCESTRY GROUP; CHILD; CHILD, PRESCHOOL; CYTIDINE DEAMINASE; FEMALE; HUMANS; INFANT; INFANT, NEWBORN; LEUKEMIA; MALE; POLYMORPHISM, SINGLE NUCLEOTIDE;

ARA;

EID: 37149050947     PISSN: 10039406     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (15)

1. Chabner BA. Cytidine analogues. In: Chabner BA, Longo DL, eds: Cancer Chemotherapy and Biotherapy. 2nd ed. Philadelphia: Lippincott-Raven Publishers, 1996.213-233.
2. Ohta T, Hon H, Ogawa M, et al. Impact of cytidine deaminase activity on intrinsic resistance to cytarabine in carcinoma cells. Oncol Rep, 2004, 12:1115-1120.
3. Ogawa M, Hori H, Ohta T, et al. Sensitivity to gemcitabine and its metabolizing enzymes in neuroblastoma. Clin Cancer Res, 2005, 11:3485-3493.
4. Schroder JK, Kirch C, Seeber S, et al. Structural and functional analysis of the cytidine deaminase gene in patients with acute myeloid leukaemia. Br J Haematol, 1998, 103:1096-1103.
5. Labberte J, Momparler RL. Human cytidine deaminase: purification of enzyme, cloning, and expression of its complementary DNA. Cancer Res, 1994, 54:5401-5407.
6. Kuhn K, Bertling WM, Emmrich F. Cloning of a functional cDNA for human cytidine deaminase (CDD) and its use as a marker of monocyte/macrophage differentiation. Biochem Biophys Res Commun, 1993, 190:1-7.
7. Watanabe S, Uchida T. Expression of cytidine deaminase in human solid tumors and its regulation by 1-alpha, 25-dihydroxyvitamin D3. Biochim Biophys Acta, 1996, 1312:99-104.
8. Yue L, Saikawa Y, Ota K, et al. A functional single-nucleotide polymorphism in the human cytidine deaminase gene contributing to ara-C sensitivity. Pharmacogenetics, 2003, 13:29-38.
9. Lijie Y. Functional analysis of a novel single-nucleotide polymorphism in the human cytidine deaminase gene. J Juzen Med Soc, 2002, 111:142-151.
10. Kirch HC, Schroder J, Hoppe H, et al. Recombinant gene products of two natural variants of the human cytidine deaminase gene confer different deamination rates of cytarabine in vitro. Exp Hematol, 1998, 26:421-425.
11. Betts L, Xiang S, Short SA, et al. Cytidine deaminase. The 2.3 A crystal structure of an enzyme: transition-state analog complex. J Mol Biol, 1994, 235:635-656.
12. Fukunaga AK, Marsh S, Murry DJ, et al. Identification and analysis of single-nucleotide polymorphisms in the gemcitabine pharmacologic pathway. Pharmacogenomics J, 2004, 4:307-314.
13. Gilbert JA, Salavaggione OE, Ji Y, et al. Gemcitabine pharmacogenomics: cytidine deaminase and deoxycytidylate deaminase gene resequencing and functional genomics. Clin Cancer Res, 2006, 12:1794-1803.
14. Sugiyama E, Kaniwa N, Kim SR, et al. Pharmacokinetics of gemcitabine in Japanese cancer patients: the impact of a cytidine deaminase polymorphism. J Clin Oncol, 2007, 25:32-42.
15. Yonemori K, Ueno H, Okusaka T, et al. Severe drug toxicity associated with a single-nucleotide polymorphism of the cytidine deaminase gene in a Japanese cancer patient treated with gemcitabine plus cisplatin. Clin Cancer Res, 2005, 11:2620-2624.