Chronic relapsing opsoclonus-myoclonus syndrome: Combination of cyclophosphamide and dexamethasone pulses

European Journal of Paediatric Neurology

Volumn 12, Issue 1, 2008, Pages 51-55

  Wilken, B ^a   Baumann, M ^a   Bien, C G ^b   Hero, B ^c   Rostasy, K ^d   Hanefeld, F ^d  

^a KLINIKUM KASSEL   (Germany)

^b UNIVERSITY OF BONN   (Germany)

^c UNIVERSITY HOSPITAL OF COLOGNE   (Germany)

^d UNIVERSITY OF GÖTTINGEN   (Germany)

Author keywords

Cyclophosphamide; Dancing eyes syndrome; Opsoclonus myoclonus syndrome; Treatment

Indexed keywords

AZATHIOPRINE; CYCLOPHOSPHAMIDE; CYCLOSPORIN; DEXAMETHASONE; DIAZEPAM; ETIRACETAM; GABAPENTIN; HALOPERIDOL; IMMUNOGLOBULIN; OLIGOCLONAL BAND; PIRACETAM; TOPIRAMATE; VALPROIC ACID;

ARTICLE; BRAIN SCINTISCANNING; CASE REPORT; CEREBELLUM DISEASE; CEREBROSPINAL FLUID; CHEMOTHERAPY; COGNITIVE DEFECT; DISEASE COURSE; DISEASE SEVERITY; DRUG MEGADOSE; ELECTROENCEPHALOGRAM; ELECTRONEUROLOGY; FEMALE; HOSPITAL ADMISSION; HUMAN; INFECTION COMPLICATION; INFORMED CONSENT; MENTAL DETERIORATION; MULTIPLE CYCLE TREATMENT; NEUROBLASTOMA; NEUROIMAGING; NUCLEAR MAGNETIC RESONANCE IMAGING; OPSOCLONUS MYOCLONUS SYNDROME; PLEOCYTOSIS; PRESCHOOL CHILD; PRIORITY JOURNAL; RELAPSE; SEROLOGY; SYMPTOMATOLOGY; TREATMENT DURATION; URINALYSIS;

ADOLESCENT; ANTI-INFLAMMATORY AGENTS; CHILD, PRESCHOOL; CYCLOPHOSPHAMIDE; DEXAMETHASONE; DRUG THERAPY, COMBINATION; FEMALE; HANDWRITING; HUMANS; IMMUNOSUPPRESSIVE AGENTS; MAGNETIC RESONANCE IMAGING; MOTOR SKILLS; OPSOCLONUS-MYOCLONUS SYNDROME; RECURRENCE;

EID: 37149044743     PISSN: 10903798     EISSN: 15322130     Source Type: Journal    
DOI: 10.1016/j.ejpn.2007.05.005     Document Type: Article

References (24)

1. Kinsbourne M. Myoclonic encephalopathy of infants. J Neurol Neurosurg Psychiatry 25 (1962) 271-276
2. Mitchell W.G., and Snodgrass SR. Opsoclonus-ataxia due to childhood neural crest tumours: a chronic neurologic syndrome. J Child Neurol 5 (1990) 153-158
3. Pohl K.R.E., Pritchard J., and Wilson J. Neurological sequelae of the dancing eye syndrome. Eur J Pediatr 155 (1996) 237-244
4. Dale R.C. Childhood opsoclonus myoclonus. Lancet Neurol 2 (2003) 270
5. Pranzatelli M.R. The neurobiology of opsoclonus-myoclonus. Clin Neuropharmacol 15 (1992) 186-228
6. Connolly A.M., Pestronk A., Mehta S., Prantazelli M.R., and Noetzel M.J. Serum antibodies in childhood opsoclonus-myoclonus syndrome: an analysis of antigenic targets in neural tissues. J Pediatr 130 (1997) 878-884
7. Matthay K.K., Blaes F., Hero B., Plantaz D., DeAlarcon P., Mitchell W.G., Pike M., and Pistoia V. Opsoclonus myoclonus syndrome in neuroblastoma a report from a workshop on the dancing eyes syndrome at the advances in neuroblastoma meeting in Genova, Italy, 2004. Cancer Lett 228 (2005) 275-282
8. Pranzatelli M.R., Travelstead A.L., Tate E.D., Allison T.J., and Verhulst S.J. CSF B-cell expansion in opsoclonus-myoclonus sindrome: a biomarker of disease activity. Mov Disord 19 (2004) 770-777
9. Pranzatelli M.R., Travelstead A.L., Tate E.D., Allison T.J., Moticka E.J., Nigro M.A., Parke J.T., Stumpf D.A., and Verhulst S.J. B- and T-cell markers in opsoclonus-myoclonus sindrome: immunophenotyping of CSF lymphocytes. Neurology 62 (2004) 1526-1532
10. Hayward K., Jeremy R.J., Jenkins S., Barkovich A.J., Gultekin S.H., Kramer J., Crittenden M., and Matthay K.K. Long-term neurobehavioral outcomes in children with neuroblastoma and opsoclonus-myoclonus-ataxia syndrome: relationship to MRI findings and anti-neuronal antibodies. J Pediatr 139 (2001) 552-559
11. Telander R.L., Smithson W.A., and Groover R.V. Clinical outcome in children with acute cerebellar encephalopathy and neuroblastoma. J Pediatr Surg 24 (1989) 11-14
12. Tate E.D., Allison T., Pranzatelli M.R., and Verhulst S.J. Neuropepidemiologic trends in 105 US cases of pediatric opsoclonus-myoclonus syndrome. J Pediatr Oncol Nurs 22 (2005) 8-19
13. Hammer M.S., Larsen M.B., and Stack C.V. Outcome of children with opsoclonus-myoclonus regardless of etiology. Pediatr Neurol 13 (1995) 21-24
14. Koh P.S., Raffensperger J.G., Berry S., Larsen M.B., Johnstone H.S., Chou P., Luck S.R., Hammer M., and Cohn S.L. Long-term outcome in children with opsoclonus-myoclonus and ataxia and coincident neuroblastoma. J Pediatr 125 (1994) 712-716
15. Pless M., and Ronthal M. Treatment of opsoclonus-myoclonus with high-dose intravenous immunoglobulin. Neurology 46 (1996) 583-584
16. Sugie H., Sugie Y., Akimoto H., Endo K., Sirai M., and Ito M. High dose IV human immunoglobulin in a case with infantile opsoclonus polymyoclonia syndrome. Acta Paediatr 18 (1992) 371-372
17. Sheela S.R., and Mani P.J. Opsoclonus-myoclonus syndrome: response to plasmapheresis. Indian Pediatrics 41 (2004) 499-502
18. Yiu V.W.Y., Kovithavongs T., McGonigle L.F., and Ferreira P. Plasmapheresis as an effective treatment for opsoclonus-myoclonus syndrome. Pediatr Neurol 24 (2001) 72-74
19. Pranzatelli M.R., Tate E.D., Travelstead A.L., and Longee D. Immunologic and clinical response to rituximab in a child with opsoclonus-myoclonus syndrome. Pediatrics 115 (2005) e115-e119
20. Mitchell W.G., Davalos-Gonzalez Y., Brumm V.L., Aller S.K., Burger E., Turkel S.B., Borchert M.S., Hollar S., and Padilla S. Opsoclonus-ataxia caused by childhood neuroblastoma: developmental and neurological sequelae. Pediatrics 109 (2002) 86-98
21. Boltshauser E., Deonna T.H., and Hirt H.R. Myoclonic encephalopathy of infants or "dancing eye syndrome". Helv Paediat Acta 34 (1979) 119-133
22. Glatz K., Meinck H.M., and Wildemann B. Parainfectious opsoclonus-myoclonus syndrome: high dose intravenous immunoglobulins are effective. J Neurol Neurosurg Psychiatry 74 (2003) 279-280
23. Rostasy K., Wilken B., Baumann M., Muller-Deile K., Bieber I., Gartner J., Moller P., Angelini P., and Hero B. High dose pulsatile dexamethasone therapy in children with opsoclonus-myoclonus syndrome. Neuropediatrics 37 (2006) 291-295
24. Oguro K., Kobayashi J., Aiba H., and Hojo H. Opsoclonus-myoclonus syndrome with abnormal single photon emission computed tomography imaging. Pediatr Neurol 16 (1997) 334-336