Stroke: encouragement and disappointment in clinical trials

The Lancet Neurology

Volumn 7, Issue 1, 2008, Pages 5-7

  Liu, Ming ^a  

^a SICHUAN UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLSALICYLIC ACID; ALTEPLASE; ANTICOAGULANT AGENT; BLOOD CLOTTING FACTOR 7; DIPYRIDAMOLE; DISUFENTON SODIUM; PLACEBO; RECOMBINANT ACTIVATED FACTOR VII; UNCLASSIFIED DRUG; WARFARIN;

ARTERY EMBOLISM; ARTICLE; BRAIN HEMORRHAGE; CARDIOVASCULAR RISK; CEREBRAL ARTERY DISEASE; CEREBROVASCULAR ACCIDENT; CLINICAL TRIAL; CONFIDENCE INTERVAL; FOLLOW UP; HEART ATRIUM FIBRILLATION; HUMAN; HYPERGLYCEMIA; MORTALITY; PRIORITY JOURNAL; STROKE; TREATMENT FAILURE; TREATMENT OUTCOME;

EID: 37149033679     PISSN: 14744422     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1474-4422(07)70300-9     Document Type: Note

References (7)

1. Vahedi K., Hofmeijer J., Juettler E., et al., for the DECIMAL, DESTINY and HAMLET investigators. Early decompressive surgery in malignant infarction of the middle cerebral artery: a pooled analysis of three randomised controlled trials. Lancet Neurol 6 (2007) 215-222
2. Mant J., Hobbs F., Fletcher K., et al., for the BAFTA investigators and the Midland Research Practices Network (MidReC). Warfarin versus aspirin for stroke prevention in an elderly community population with atrial fibrillation (the Birmingham Atrial Fibrillation Treatment of the Aged Study, BAFTA): a randomised controlled trial. Lancet 370 (2007) 493-503
3. Shuaib A., Lees K., Lyden P., et al., for the SAINT II trial investigators. NXY-059 for the treatment of acute ischemic stroke. N Engl J Med 357 (2007) 562-571
4. Mayer S., Brun N., Begtrup K., et al. Recombinant activated factor VII for acute intracerebral hemorrhage. N Engl J Med 352 (2005) 777-785
5. Mayer S., Brun N., Begtrup K., et al. Randomized, placebo-controlled, double-blind phase III study to assess rFVIIa efficacy in acute cerebral haemorrhage: the FAST trial. Cerebrovasc Dis 23 suppl 2 (2007) 10. http://www.ciap.health.nsw.gov.au/nswtag/publications/posstats/Eptacogad dendum0807.pdf (accessed Nov 20).
6. The ESPRIT Study Group, and Algra A. Medium intensity oral anticoagulants versus aspirin after cerebral ischaemia of arterial origin (ESPRIT): a randomised controlled trial. Lancet Neurol 6 (2007) 115-124
7. Gray C., Hildreth A., Sandercock P., et al., for the GIST trialists collaboration. Glucose-potassium-insulin infusions in the management of post-stroke hyperglycaemia: the UK Glucose Insulin in Stroke Trial (GIST-UK). Lancet Neurol 6 (2007) 397-406