High rate of conversion to Alzheimer's disease in a cohort of amnestic MCI patients

International Psychogeriatrics

Volumn 20, Issue 1, 2008, Pages 96-108

  Schmidtke, Klaus ^a   Hermeneit, Sonja ^b  

^a UNIVERSITY OF FREIBURG   (Germany)

^b NONE

Author keywords

Alzheimer's disease; Amnestic MCI; Dementia

Indexed keywords

AGED; ALZHEIMER DISEASE; AMNESIA; ARTICLE; COGNITIVE DEFECT; COHORT ANALYSIS; CONTROLLED STUDY; DISEASE COURSE; FEMALE; FOLLOW UP; HIGH RISK PATIENT; HUMAN; LEARNING; MAJOR CLINICAL STUDY; MALE; MEMORY; MENTAL TASK; NEUROPSYCHOLOGICAL TEST; PREDICTION; PROSPECTIVE STUDY; TUBERCULOUS LYMPHADENITIS;

AGED; ALZHEIMER DISEASE; COGNITION DISORDERS; COHORT STUDIES; DISEASE PROGRESSION; FEMALE; FOLLOW-UP STUDIES; HUMANS; INCIDENCE; MALE; MEMORY DISORDERS; NEUROPSYCHOLOGICAL TESTS; OUTCOME ASSESSMENT (HEALTH CARE); PREDICTIVE VALUE OF TESTS; PREVALENCE; PROGNOSIS; PROSPECTIVE STUDIES; PSYCHIATRIC STATUS RATING SCALES; SEVERITY OF ILLNESS INDEX;

EID: 37149008054     PISSN: 10416102     EISSN: 1741203X     Source Type: Journal    
DOI: 10.1017/S1041610207005509     Document Type: Article

References (29)

1. Bowen, J., Teri, L., Kukull, W., McCormick, W., McCurry, S. M. and Larson, E. B. (1997). Progression to dementia in patients with isolated memory loss. Lancet, 349, 763-765.
2. Bruscoli, M. and Lovestone, S. (2004). Is MCI really just early dementia? A systematic review of conversion studies. International Psychogeriatrics, 16, 129-140.
3. Busse, A., Bischkopf, J., Riedel-Heller, S. G. and Angermeyer, M. C. (2003). Subclassifications for mild cognitive impairment: prevalence and predictive validity. Psychological Medicine, 33, 1029-1038.
4. Chertkow, H. (2002). Mild cognitive impairment. Current Opinion in Neurology, 15, 401-407.
5. Feldman, H. et al. (2004). Behavioral symptoms in mild cognitive impairment. Neurology, 62, 1199-1201.
6. Flicker, C., Ferris, S. H. and Reisberg, B. (1991). Mild cognitive impairment in the elderly: predictors of dementia. Neurology, 41, 1006-1009.
7. Galvin, J. E. et al. (2005). Predictors of preclinical Alzheimer's disease and dementia. Archives of Neurology, 62, 758-765.
8. Geslani, D. M., Tierney, M. C., Herrmann, N. and Szalai, J. P. (2005). Mild cognitive impairment: an operational definition and its conversion rate to Alzheimer's disease. Dementia and Geriatric Cognitive Disorders, 19, 383-389.
9. Goldstein, H. R. and Gold, M. (2004). Galantamine in the treatment of patients with mild cognitive impairment: baseline demographics and psychometric testing results. Neurobiology of Aging, 25 (suppl. 2), S472-S473.
10. Jelic, V., Kivipelto, M. and Winblad, B. (2006). Clinical trials in mild cognitive impairment: lessons for the future. Journal of Neurology, Neurosurgery, and Psychiatry, 77, 429-436.
11. McKhann, G. et al. (1984). Clinical diagnosis of Alzheimer's disease: report of the NINCDS-ARDRA work group under the auspices of Department of Health and Human Service Task Force on Alzheimer's Disease. Neurology, 34, 939-944.
12. McKeith, I. et al. (2004). Dementia with Lewy bodies. Lancet Neurology, 3, 19-28.
13. Morris, J. C. (1993). The Clinical Dementia Rating (CDR): current version and scoring rules. Neurology, 43, 2412-2414.
14. Nordlund, A., Rolstad, S., Hellstrom, P., Sjogren, M., Hansen, S. and Wallin, A. (2005). The Göteborg MCI study: mild cognitive impairment is a heterogeneous condition. Journal of Neurology, Neurosurgery, and Psychiatry, 76, 1485-1490.
15. Petersen, R. C. and Morris, J. C. (2005). Mild cognitive impairment as a clinical entity and treatment target. Archives of Neurology, 62, 1160-1163.
16. Petersen, R. C., Smith, G. E., Waring, A. C., Ivnik, R. J., Tangalos, E. G. and Kokmen, E. (1999). Mild cognitive impairment: clinical characterization and outcome. Archives of Neurology, 56, 303-308.
17. Petersen, R. C., Stevens, J. C., Ganguli, M., Tangalos, E. G., Cummings, J. L. and DeKosky, S. T. (2001a). Practice parameter: early detection of dementia. Mild cognitive impairment (an evidence-based review). Report of the Quality Standards Subcommittee of the American Academy of Neurology. Neurology, 56, 1133-1142.
18. Petersen, R. C. et al. (2001b). Current concepts in mild cognitive impairment. Archives of Neurology, 58, 1985-1992.
19. Petersen, R. C. et al. (2005). Vitamin E and donezepil for the treatment of mild cognitive impairment. New England Journal of Medicine, 352, 2439-2441.
20. Rasquin, S. M. C., Lodder, J., Visser, P. J., Lousberg, R. and Verhay, F. R. J. (2005). Predictive accuracy of MCI subtypes for Alzheimer's disease and vascular dementia in subjects with mild cognitive impairment: a 2-year follow-up study. Dementia and Geriatric Cognitive Disorders, 19, 113-119.
21. Ritchie, K., Artero, S. and Touchon, J. (2001). Classification criteria for mild cognitive impairment: a population-based validation study. Neurology, 56, 37-42.
22. Satzger, W. et al. (2001). Zur praktischen Anwendung der CERAD-Testbatterie als neuropsychologisches Defizitscreening. Nervenarzt, 72, 196-203.
23. Schmidtke, K. and Ḧull, M. (2002). Neuropsychological differentiation of small vessel disease, Alzheimer's disease and mixed dementia. Journal of the Neurological Sciences, 9, 419-429.
24. Schmidtke, K. and Olbrich, S. (2007). The Clock Reading Test - validation of an instrument for the diagnosis of dementia and disorders of visuo-spatial cognition. International Psychogeriatrics, 19, 307-321.
25. Shulman, K. I. (2000). Clock-drawing: is it the ideal cognitive screening test? International Journal of Geriatric Psychiatry, 15, 548-561.
26. Tierney, M. C. et al. (1999). Do depressive symptoms in memory-impaired elders predict probable Alzheimer's disease? Aging and Mental Health, 3, 88-93.
27. Visser, P. J., Scheltens, P. and Verhey, F. R. J. (2005). Do MCI criteria in drug trials accurately identify subjects with predementia Alzheimer's disease? Journal of Neurology, Neurosurgery, and Psychiatry, 76, 1348-1354.
28. Visser, P. J., Kester, A., Jolles, J. and Verhey, F. (2006). Ten-year risk of dementia in subjects with mild cognitive impairment. Neurology, 67, 1201-1207.
29. Winblad, B. et al. (2004). Mild cognitive impairment - beyond controversies, towards a consensus. Report of the International Working Group on Mild Cognitive Impairment. Journal of Internal Medicine, 256, 240-246.