Activation of the 5-HT1B/D receptor reduces hindlimb neurogenic inflammation caused by sensory nerve stimulation and capsaicin

Pain

Volumn 134, Issue 1-2, 2008, Pages 97-105

  Carmichael, Nicole M E ^a   Charlton, Milton P ^a   Dostrovsky, Jonathan O ^a  

^a UNIVERSITY OF TORONTO   (Canada)

Author keywords

5 HT1B D receptor agonists; CGRP; Neurogenic inflammation; Nociceptor; Plasma extravasation; Substance P; Sumatriptan; Vasodilation

Indexed keywords

CALCITONIN GENE RELATED PEPTIDE; CAPSAICIN; N [4 METHOXY 3 (4 METHYL 1 PIPERAZINYL)PHENYL] 2' METHYL 4' (5 METHYL 1,2,4 OXADIAZOL 3 YL)[1,1' BIPHENYL] 4 CARBOXAMIDE; NEUROPEPTIDE; SEROTONIN 1B AGONIST; SEROTONIN 1B ANTAGONIST; SEROTONIN 1B RECEPTOR; SEROTONIN 1D AGONIST; SEROTONIN 1D ANTAGONIST; SEROTONIN 1D RECEPTOR; SUBSTANCE P; SUMATRIPTAN; SEROTONIN AGONIST;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; ELECTROSTIMULATION; EXTRAVASATION; HINDLIMB; INFLAMMATION; LEG BLOOD FLOW; MALE; NERVE STIMULATION; NOCICEPTION; NONHUMAN; PAIN; PLASMA; PRIORITY JOURNAL; RAT; SAPHENOUS NERVE; SENSORY NERVE; SEROTONINERGIC SYSTEM; TREATMENT OUTCOME; VASODILATATION; ANIMAL; CHEMICALLY INDUCED DISORDER; COMPARATIVE STUDY; DRUG EFFECT; DRUG POTENTIATION; METABOLISM; NEUROGENIC INFLAMMATION; SENSORY NERVE CELL; SPRAGUE DAWLEY RAT; VASCULARIZATION;

ANIMALS; CAPSAICIN; HINDLIMB; MALE; NEUROGENIC INFLAMMATION; NEURONS, AFFERENT; RATS; RATS, SPRAGUE-DAWLEY; RECEPTOR, SEROTONIN, 5-HT1B; RECEPTOR, SEROTONIN, 5-HT1D; SEROTONIN AGONISTS; SUMATRIPTAN;

EID: 37149000036     PISSN: 03043959     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.pain.2007.03.037     Document Type: Article

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