Synthesis of 6-hydroximino-3-oxo steroids, a new class of aromatase inhibitor

Journal of the Chemical Society, Perkin Transactions 1

Volumn , Issue 5, 1992, Pages 585-587

  Holland, Herbert L ^a   Kumaresan, Sudalaiyandi ^a   Tan, Liat ^b   Njar, Vincent C O ^b,c  

^a BROCK UNIVERSITY   (Canada)

^b UNIVERSITÉ DE SHERBROOKE   (Canada)

^c Medical Research Council of Canada ^*

Author keywords

[No Author keywords available]

Indexed keywords

EID: 37049086433     PISSN: 14727781     EISSN: None     Source Type: Journal    
DOI: 10.1039/p19920000585     Document Type: Article

References (22)

1. D. F. Covey, W. F. Hood and V. D. Parikh, J. Biol. Chem., 1981,256, 1076.
2. P. J. Bednarsky and S. D. Nelson, J. Med. Chem., 1989,32, 203.
3. J.T. Kellis, W. E. Childers, C. H. Robinson and L. E. Vickery, J. Biol. Chem., 1987,262,4421.
4. A. M. H. Brodie, W. M. Garrett, J. R. Hendrickson, C. H. Tsai- Morris, P. A. Marcotte and C. H. Robinson, Steroids, 1981,38, 393.
5. M. Numazawa, M. Tsuji and A. Mutsumi, J. Steroid Biochem., 1987, 28, 337.
6. C. E. Snider and R. W. Bruggemeier, J. Biol. Chem., 1987,262,8685.
7. M. Yoshihama, K. Tamura, M. Nakakoshi, J. Makamura, N. Fujise and G. Kawanishi, Chem. Pharm. Bull., 1990, 38,2834.
8. J. N. Wright, M. R. Calder and M. Akhtar, J. Chem. Soc., Chem. Commun., 1985, 1733.
9. L. Tan, V. C. O. Njar, S. Kumaresan and H. L. Holland, presented at the International Symposium on Cytochrome P-450, Moscow, July 1991.
10. M. Anastasia, P. Allevi, P. CiufTreda and A. Fiecchi, J. Chem. Soc., Perkin Trans. I, 1986,2123.
11. H. Singh and K. K. Bhutani, Ind. J. Chem., Sect. B, 1978,16,95.
12. J. T. Pinhey, E. Rizzardo and G. C. Smith, Aust. J. Chem., 1978,31,97.
13. K. Oka and S. Hara, J. Org. Chem., 1978,43,3790.
14. J. W. Blunt and J. B. Stothers, Org. Magn. Reson., 1977, 9, 439.
15. H. L. Holland, P. R. P. Diakow and G. J. Taylor, Can. J. Chem., 1978, 56,3121.
16. H. L. Holland and E. M. Thomas, Can. J. Chem., 1979,57,3069.
17. L. L. Smith in Biotechnology, eds. H. J. Rehm and G. Reed, vol. 6A, ed. K. Kieslich, Verlag Chemie, Weinheim, 1984, p. 67.
18. C. C. Beard in Organic Reactions in Steroid Chemistry, eds. J. Fried and J. A. Edwards, van Nostrand Reinhold, New York, 1972, vol 1, p. 306.
19. H. L. Holland, J. A. Rao and P. C. Chenchaiah, J. Chem. Soc., Perkin Trans. 1, 1988, 2027.
20. M. Ackroyd, W. J. Adams, B. Ellis, V. Petrow and I. A. Stuart-Webb, J. Chem. Soc., 1957,4099.
21. L. Knof, Ann. Chem., 1962,657, 171.
22. Y. Lefebvre, U.S.P. 3,294,823 (Dec. 27th, 1966) (Chem. Abstr., 1967, 66,65756h).