13C and 15N NMR evidence for peripheral intercalation of uniformly labeled fusogenic peptides incorporated in a biomimetic membrane

Biochimica et Biophysica Acta - Biomembranes

Volumn 1768, Issue 12, 2007, Pages 3020-3028

  Agrawal, Prashant ^a   Kiihne, Suzanne ^a   Hollander, Johan ^a   Langosch, Dieter ^b   de Groot, Huub ^a  

^a LEIDEN UNIVERSITY   (Netherlands)

^b TECHNICAL UNIVERSITY OF MUNICH   (Germany)

Author keywords

Membrane fusion; Oriented bilayer; Solid state NMR; Transmembrane membrane fusogenic polypeptide

Indexed keywords

MEMBRANE FUSION PROTEIN; PEPTIDE DERIVATIVE; CARBON; NITROGEN; PEPTIDE;

ARTICLE; BIOMIMETICS; CELL MEMBRANE; EXPERIMENTAL STUDY; HYDROPHOBICITY; MEMBRANE FUSION; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN ANALYSIS; PROTEIN INTERACTION; PROTEIN SYNTHESIS; SOLID STATE; AMINO ACID SEQUENCE; BIOLOGICAL MODEL; CHEMISTRY; LIPID BILAYER; METHODOLOGY; MOLECULAR GENETICS;

AMINO ACID SEQUENCE; BIOMIMETICS; CARBON ISOTOPES; HYDROPHOBICITY; LIPID BILAYERS; MAGNETIC RESONANCE SPECTROSCOPY; MEMBRANE FUSION; MODELS, BIOLOGICAL; MOLECULAR SEQUENCE DATA; NITROGEN ISOTOPES; PEPTIDES;

EID: 37049031933     PISSN: 00052736     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbamem.2007.09.024     Document Type: Article

References (21)

1. Wasniewski C.M., Parkanzky P.D., Bodner M.L., and Weliky D.P. Solid-state nuclear magnetic resonance studies of HIV and influenza fusion peptide orientations in membrane bilayers using stacked glass plate samples. Chem. Phys. Lipids 132 (2004) 89-100
2. 15N labelled de novo designed membrane fusogenic peptides. J. Pept. Sci. 13 (2006) 75-80
3. Hofmann M., Weise K., Ollesch J., Agrawal P., Stalz H., Stelzer W., Hulsbergen F., de Groot H., Gerwert K., Reed J., and Langosch D. De novo design of conformationally flexible transmembrane peptides driving membrane fusion. Proc. Natl. Acad. Sci. U. S. A. 101 (2004) 14776-14781
4. Agrawal P., Kiihne S., Hollander J., Hulsbergen F., Hofmann M., Langosch D., and de Groot H. Solid state NMR investigation of the interaction between biomimetic lipid bilayers and de novo designed fusogenic peptides. ChemBioChem 8 (2007) 493-496
5. Huster D., Yao X., and Hong M. Membrane protein topology probed by 1H spin diffusion from lipids using solid-state NMR spectroscopy. J. Am. Chem. Soc. 124 (2002) 874-883
6. Raap J., Hollander J., Ovchinnikova T.V., Swischeva N.V., Skladnev D., and Kiihne S. Trans and surface membrane bound zervamicin IIB: 13C-MAOSS-NMR at high spinning speed. J. Biomol. NMR V35 (2006) 285
7. Aisenbrey C., and Bechinger B. Investigations of polypeptide rotational diffusion in aligned membranes by H-2 and N-15 solid-state NMR spectroscopy. J. Am. Chem. Soc. 126 (2004) 16676-16683
8. Bechinger B., Kinder R., Helmle M., Vogt T.C.B., Harzer U., and S.S. Peptide structural analysis by solid-state NMR spectroscopy Review. Biopolym. Pept. Sci. 51 (1999) 174-190
9. Cross T.A. Solid-state nuclear magnetic resonance characterization of gramicidin channel structure. Methods Enzymol. 289 (1997) 672-696
10. Watts A. NMR of drugs and ligands bound to membrane receptors. Curr. Opin. Biotechnol. 10 (1999) 48-53
11. Ramamoorthy A., Thennarasu S., Lee D.-K., Tan A., and Maloy L. Solid-state NMR investigation of the membrane-disrupting mechanism of antimicrobial peptides MSI-78 and MSI-594 derived from magainin 2 and melittin. Biophys. J. 91 (2006) 206-216
12. Bechinger B. The structure, dynamics and orientation of antimicrobial peptides in membranes by multidimensional solid-state NMR spectroscopy. Biochim. Biophys. Acta, Biomembr. 1462 (1999) 157-183
13. 31P solid-state NMR spectroscopy. Concepts Magn. Reson. Part A 18A (2003) 130-145
14. Deutsch J.W., and Kelly R.B. Lipids of synaptic vesicles: relevance to the mechanism of membrane fusion. Biochemistry 20 (1981) 378-385
15. Langosch D., Crane J.M., Brosig B., Hellwig A., Tamm L.K., and Reed J. Peptide mimics of SNARE transmembrane segments drive membrane fusion depending on their conformational plasticity. J. Mol. Biol. 311 (2001) 709-721
16. Hofmann M.W., Peplowska K., Rohde J., Poschner B.C., Ungermann C., and Langosch D. Self-interaction of a SNARE transmembrane domain promotes the hemifusion-to-fusion transition. J. Mol. Biol. 364 (2006) 1048
17. 15N labelled de novo designed membrane fusogenic peptides. J. Pept. Sci. 13 (2006) 75-80
18. Rance M., and Byrd R.A. Obtaining high-fidelity spin-1/2 powder spectra in anisotropic media - phase-cycled Hahn Echo Spectroscopy. J. Magn. Reson. 52 (1983) 221-240
19. Kameda T., Takeda N., Kuroki S., Kurosu H., Ando S., Ando I., Shoji A., and Ozaki T. Hydrogen-bonded structure and C-13 NMR chemical shift tensor of amino acid residue carbonyl carbons of peptides and polypeptides in the crystalline state. 1. J. Mol. Struct. 384 (1996) 17-23
20. Ollesch J., Poschner B.C., Nikolaus J., Hofmann M.W., Hermann A., Gerwert K., and Langosch D. Biophys. J. (2007)
21. Porcelli F., Buck B., Lee D.K., Hallock K.J., Ramamoorthy A., and Veglia G. Structure and orientation of pardaxin determined by NMR experiments in model membranes. J. Biol. Chem. 279 (2004) 45815-45823