Genetic polymorphisms of TLR3 are associated with Nasopharyngeal carcinoma risk in Cantonese population

BMC Cancer

Volumn 7, Issue , 2007, Pages

  He, Jun Fang ^a,b   Jia, Wei Hua ^a,b   Fan, Qin ^a,b   Zhou, Xin Xi ^a,b   Qin, Hai De ^a,b   Shugart, Yin Yao ^c   Zeng, Yi Xin ^a,b  

^a SUN YAT SEN UNIVERSITY CANCER CENTER   (China)

^b SUN YAT SEN UNIVERSITY   (China)

^c JOHNS HOPKINS BLOOMBERG SCHOOL OF PUBLIC HEALTH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

IMMUNOGLOBULIN A ANTIBODY; TOLL LIKE RECEPTOR 3; TLR3 PROTEIN, HUMAN;

ADULT; ALLELE; ARTICLE; CANCER RISK; CANCER SUSCEPTIBILITY; CHINA; CONTROLLED STUDY; DNA SEQUENCE; FEMALE; GENETIC ASSOCIATION; GENETIC POLYMORPHISM; GENETIC RISK; GENETIC SUSCEPTIBILITY; GENETIC VARIABILITY; GENOTYPE; HAPLOTYPE; HUMAN; MAJOR CLINICAL STUDY; MALE; NASOPHARYNX CARCINOMA; POLYMERASE CHAIN REACTION; POPULATION BASED CASE CONTROL STUDY; SINGLE NUCLEOTIDE POLYMORPHISM; ASIAN; CASE CONTROL STUDY; ENDEMIC DISEASE; ETHNOLOGY; GENE FREQUENCY; GENETICS; MIDDLE AGED; NASOPHARYNX TUMOR; RISK ASSESSMENT;

ADULT; ASIAN CONTINENTAL ANCESTRY GROUP; CASE-CONTROL STUDIES; CHINA; ENDEMIC DISEASES; FEMALE; GENE FREQUENCY; GENOTYPE; HAPLOTYPES; HUMANS; MALE; MIDDLE AGED; NASOPHARYNGEAL NEOPLASMS; POLYMORPHISM, SINGLE NUCLEOTIDE; RISK ASSESSMENT; TOLL-LIKE RECEPTOR 3;

EID: 37049010741     PISSN: None     EISSN: 14712407     Source Type: Journal    
DOI: 10.1186/1471-2407-7-194     Document Type: Article

References (45)

1. Yu MC Yuan JM Epidemiology of nasopharyngealcarcinoma Semin Cancer Biol 2002, 12:421-429 10.1016/S1044579X02000858 12450728
2. Chan TC Teo ML Johnson J Nasopharyngeal carcinoma Annals of oncology 2002, 13:1007-1015 10.1093/annonc/mdf179 12176778
3. Feng BJ Huang W Shugart YY Lee MK Zhang F Xia JC Wang HY Huang TB Jian SW Huang P Feng QS Huang LX Yu XJ Li D Chen LZ Jla WH Fang Y Huang HM Zhu JL Liu XM Zhao Y Liu WQ Deng MQ Hu WH Wu SX Mo HY Hong MF King MC Chen Z Zeng YX Genome-wide scan for familial nasopharyngeal carcinoma reveals evidence of linkage to chromosome 4 Nat Genet 2002, 31:395-399 12118254
4. Xiong W Zeng ZY Xia JH Shen SR Li XL Hu DX Tan C Xiang JJ Zhou J Deng H Fan SQ A susceptibility locus at chromosome 3p21 linked to familial nasopharyngeal carcinoma Cancer Res 2004, 64:1972-1974 10.1158/ 0008-5472.CAN-03-3253 15026332
5. Jalbout M Bouaouina N Gargouri J Corbex M Ben Ahmed S Chouchane L Polymorphism of the stress protein HSP70-2 gene is associated with the susceptibility to the nasopharyngeal carcinoma Cancer Lett 2003, 193:75-81 10.1016/S0304-3835(02)00697-3 12691826
6. Hirunsatit R Kongruttanachok N Shotelersuk K Supiyaphun P Voravud N Sakuntabhai A Mutirangura A Polymeric immunoglobulin receptor polymorphisms and risk of nasopharyngeal cancer BMC Genet 2003, 4:3 149362 12546713 10.1186/1471-2156-4-3
7. Vasef MA Ferlito A Weiss LM Nasopharyngeal carcinoma, with emphasis on its relationship to Epstein-Barr virus Ann Otol Rhinol Laryngol 1997, 106:348-356 9109729
8. Niedobitek G Hansmann LM Herbst H Young LS Dienemann D Hartmann CA Epstein-Barr virus and carcinoma; undifferentiated carcinoma but not squamous cell carcinomas of the nasopharynx are regularly associated with the virus J Pathol 1991, 165:17-24 10.1002/path.1711650105 1659626
9. Zong YS Sham JS Ng MH Ou XT Guo YQ Zheng SA Liang JS Qiu H Immunoglobulin A against viral capsid antigen of Epstein-Barr virus and indirect mirror examination of the nasopharynx in the detection of asymptomatic nasopharyngeal carcinoma Cancer 1992, 69:3-7 10.1002/ 1097-0142(19920101)69:1<3::AID-CNCR2820690104>3.0.CO;2-7 1309307
10. Wolf H Zur Hausen H Becker V EB virus genomes in epithelial nasopharyngeal carcinoma cells Nature 1973, 244:245-247
11. IARC Monographs on the Evaluation of Carcinogenic Risks to Humans Epstein-Barr virus and Kaposi's Sarcoma Herpesvirus/Human Herpesvirus 8 IARC, Lyon 1977 70
12. Vaughan TL Stewart PA Teschke K Lynch CF Swanson GM Lyon JL Berwick M Occupational exposure to formaldehyde and wood dust and nasopharyngeal cancer Occup Environ Med 2000, 57:376-384 10.1136/oem.57.6.376 10810126
13. Mirabelli MC Hoppin JA Tolbert PE Herrick RF Gnepp DR Brann EA Occupational exposure to chlorophenol and the risk of nasal and nasopharyngeal cancers among US men aged 30 to 60 Am J Ind Med 2000, 37:532-541 10.1002/(SICI)1097-0274(200005)37:5<532::AID- AJIM9>3.0.CO;2-A 10723047
14. Armstrong RW Imrey PB Lye MS Armstrong MJ Yu MC Sani S Nasopharyngeal carcinoma in Malaysian Chinese: Salted fish and other dietary exposures Int J Cancer 1998, 77:228-235 10.1002/ (SICI)1097-0215(19980717)77:2<228::AID-IJC11>3.0.CO;2-7 9650558
15. Farrow DC Vaughan TL Berwick M Lynch CF Swanson GM Lyon JL Diet and nasopharyngeal cancer in a lowrisk population Int J Cancer 1998, 78:675-679 10.1002/(SICI)1097-0215(19981209)78:6<675::AID- IJC2>3.0.CO;2-J 9833758
16. Busson Pierre Keryer Ce cile Ooka Tadamassa Corbex Marilys EBV-associated nasopharyngeal carcinomas: From epidemiology to virus-targeting strategies TRENDS in Microbiology 2004, 12:356-360 10.1016/j.tim.2004.06.005 15276610
17. Bickham K Munz C Contrasting roles of dendritic cells and B cells in the immune control of Epstein-Barr virus Curr Top Microbiol Immunol 2003, 276:55-76 12797443
18. Iwatsuki Rev Keiji Yamamoto Takenobu Tsuji Kazuhide A Spectrum of Clinical Manifestations Caused by Host Immune Responses against Epstein-Barr Virus Infections Acta Med Okayama 2004, 58:169-180 15551754
19. Edwards RH Sitki-Green D Moore DT Raab-Traub N Potential selection of LMP1 variants in nasopharyngeal carcinoma J Virol 2004, 78:868-881 368819 14694118 10.1128/JVI.78.2.868-881.2004
20. Lee SP Chan ATC Cheung ST Thomas WA Croom-Carter D Dawson CW Tsai CH Leung SF Johnson PJ Huang DP Cytotoxic T lymphocyte control of Epstein-Barr virus in nasopharyngeal carcinoma(NPC): EBV-specific CTL response in the blood and tumor of NPC patient and the antigen processing function of the tumor cells J Immunol 2000, 165:573-582 10861098
21. Takeda K Kaisho T Akira S Toll-like receptors Annu Rev Immunol 2003, 21:335-376 10.1146/annurev.immunol.21.120601.141126 12524386
22. Iwasaki Akiko Medzhitov Ruslan Toll-like receptor control of the adaptive immune responses Nature Immunology 2004, 5:987-995 10.1038/ ni1112 15454922
23. Aderem A Ulevitch RJ Toll-like receptors in the induction of the innate immune response Nature 2000, 406:782-787 10.1038/35021228 10963608
24. Medzhitov R Toll-like receptors and innate immunity Nat Rev Immunol 2001, 1:135-145 10.1038/35100529 11905821
25. Beutler B Inferences, questions and possibilities in Toll-like receptor signalling Nature 2004, 430:257-263 10.1038/nature02761 15241424
26. Le Bon A Tough DF Links between innate and adaptive immunity via type I interferon Curr Opin Immunol 2002, 14:432-436 10.1016/ S0952-7915(02)00354-0 12088676
27. Lawton JA Ghosh P Novel therapeutic strategies based on toll-like receptor signaling Curr Opin Chem Biol 2003, 7:446-451 10.1016/ S1367-5931(03)00077-2 12941417
28. Rassa C John Ross R Susan Virus and Toll-like receptors Microbes and infection 2003, 5:961-968 10.1016/S1286-4579(03)00193-X
29. Krug A Luker GD Barchet W Leib DA Akira S Colonna M Herpes simplex virus type 1 activates murine natural interferon-producing cells through toll-like receptor 9 Blood 2004, 103: 1433-1437 10.1182/ blood-2003-08-2674 14563635
30. Kurt-Jones EA Popova L Kwinn L Haynes LM Jones LP Tripp RA Walsh EE Freeman MW Golenbock DT Anderson LJ Finberg RW Pattern recognition receptors TLR4 and CD14 mediate response to respiratory syncytial virus Nat Immunol 2000, 1:398-401 10.1038/80833 11062499
31. A Kiss-Toth E Symons JA Smith GL Dower SK O'Neill LA A46R and A52R from vaccinia virus are antagonists of host IL-1 and toll-like receptor signaling Proc Natl Acad Sci USA 2000, 97:10162-10167 27775 10920188 10.1073/pnas.160027697
32. Compton T Kurt-Jones EA Boehme KW Belko J Latz E Golenbock DT Finberg RW Human cytomegalovirus activates inflammatory cytokine responses via CD14 and Toll-like receptor 2 J Virol 2003, 77:4588-4596 152130 12663765 10.1128/JVI.77.8.4588-4596.2003
33. Schmidt KN Leung B Kwong M Zarember KA Satyal S Navas TA Wang F Godowski PJ APC-independent activation of NK cells by the Toll-like receptor 3 agonist double-stranded RNA J Immunol 2004, 172:138-143 14688319
34. Diebold S Sandra Montoya Maria Unger Hermann Alexopoulou Lena Roy Polly Haswell E Linsey Al-Shamkhani Aymen Flavell Richard Borrow Persephone Reis e Sousa Caetano Viral infection switches nonplasmacytoid dendritic cells into high interferon producers Nature 2003, 424:324-328 10.1038/ nature01783 12819664
35. Doyle E Sean O'Connell Ryan Vaidya A Sagar Chow K Edward Yee Kathleen Cheng Genhong Toll-Like Receptor 3 Mediates a More Potent Antiviral Response Than Toll-Like Receptor 4 The Journal of Immunology 2003, 170:3565-3571 12646618
36. Tough DF Sun S Zhang X Sprent J Stimulation of naive and memory T cells by cytokines Immunol Rev 1999, 170:39-47 10.1111/ j.1600-065X.1999.tb01327.x 10566140
37. Schroder NW Schumann RR Single nucleotide polymorphisms of Toll-like receptors and susceptibility to infectious disease Lancet Infect Dis 2005, 5:156-164 15766650
38. Arbour NC Lorenz E Schutte BC Zabner J Kline JN Jones M Frees K Watt JL Schwartz DA TLR4 mutations are associated with endotoxin hyporesponsiveness in humans Nat Genet 2000, 25:187-191 10.1038/76048 10835634
39. Lazarus R Klimecki WT Raby BA Vercelli D Palmer LJ Kwiatkowski DJ Silverman EK Martinez F Weiss ST Single-nucleotide polymorphisms in the Toll-like receptor 9 gene (TLR9): Frequencies, pairwise linkage disequilibrium, and haplotypes in three U.S. ethnic groups and exploratory case-control disease association studies Genomics 2003, 81:85-91 10.1016/S0888-7543(02)00022-8 12573264
40. Tantisira K Klimecki WT Lazarus R Palmer LJ Raby BA Kwiatkowski DJ Silverman E Vercelli D Martinez FD Weiss ST Toll-like receptor 6 gene (TLR6): Single-nucleotide polymorphism frequencies and preliminary association with the diagnosis of asthma Genes Immun 2004, 5:343-346 10.1038/sj.gene.6364096 15266299
41. Redecke V Hacker H Datta SK Fermin A Pitha PM Broide DH Raz E Cutting edge: Activation of toll-like receptor 2 induces a Th2 immune response and promotes experimental asthma J Immunol 2004, 172:2739-2743 14978071
42. http://frodo.wi.mit.edu
43. Cheung F Pang SW Hioe F Cheung KN Lee A Yau TK Nasopharyngeal carcinoma in situ: Two cases of an emerging diagnostic entity Cancer 1998, 83:1069-1073 10.1002/(SICI)1097-0142(19980915)83:6<1069::AID- CNCR3>3.0.CO;2-3 9740069
44. Mutirangura A Tanunyutthawongese C Pornthanakasem W Kerekhanjanarong V Sriuranpong V Yenrudi S Supiyaphun P Voravud N Genomic alterations in nasopharyngeal carcinoma: Loss of heterozygosity and Epstein-Barr virus infection Br J Cancer 1997, 76:770-776 9310244
45. Lohmueller KE Pearce CL Pike M Lander ES Hirschhorn JN Meta-analysis of genetic association studies supports a contribution of common variants to susceptibility to common disease Nat Genet 2003, 33:177-182 10.1038/ ng1071 12524541