Bay w 9798, a dihydropyridine structurally related to nifedipine with no calcium channel-blocking properties, inhibits tumour necrosis factor-α-induced vascular cell adhesion molecule-1 expression in endothelial cells by suppressing reactive oxygen species generation

Journal of International Medical Research

Volumn 35, Issue 6, 2007, Pages 886-891

  Matsui, T ^a   Yamagishi, Sho Ichi ^a   Nakamura, K ^a   Inoue, H ^a  

^a KURUME UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Atherosclerosis; Bay w 9798; Dihydropyridines; Human umbilical vein endothelial cells (HUVECs); Nifedipine; Oxidative stress; Tumour necrosis factor (TNF ); Vascular cell adhesion molecule 1 (VCAM 1)

Indexed keywords

1,2,6 TRIMETHYL 4 (4 TRIFLUOROMETHYLPHENYL) 1,4 DIHYDROPYRIDINE 3,5 DICARBOXYLIC ACID DIMETHYL ESTER; BAY W 9798; CALCIUM CHANNEL; CELL ADHESION MOLECULE; CELL ADHESION MOLECULE 1; DIHYDROPYRIDINE; NIFEDIPINE; REACTIVE OXYGEN METABOLITE; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANTIINFLAMMATORY ACTIVITY; ANTIOXIDANT ACTIVITY; ARTICLE; ATHEROSCLEROSIS; CELL ADHESION; CONTROLLED STUDY; DRUG STRUCTURE; ENDOTHELIUM CELL; GENE EXPRESSION REGULATION; HUMAN; HUMAN CELL; MONOCYTE; RECEPTOR BLOCKING; UMBILICAL VEIN; UPREGULATION;

EID: 36949040856     PISSN: 03000605     EISSN: None     Source Type: Journal    
DOI: 10.1177/147323000703500617     Document Type: Article

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