Determining intravenous rt-PA eligibility in the emergency department

Neurocritical Care

Volumn 7, Issue 2, 2007, Pages 103-108

  Mecozzi, Amy C ^a   Brown, Devin L ^a   Lisabeth, Lynda D ^a,b   Barsan, William G ^a   Silbergleit, Robert ^a   Hickenbottom, Susan L ^c   Scott, Phillip A ^a   Morgenstern, Lewis B ^a,b  

^a UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^b UNIVERSITY OF MICHIGAN SCHOOL OF PUBLIC HEALTH   (United States)

^c Saint Joseph Mercy Health System   (United States)

Author keywords

Cerebrovascular accident; Education; Emergency service; Graduate; Hospital; Medical; Thrombolytic therapy; Tissue plasminogen activator

Indexed keywords

ALTEPLASE;

ADULT; ARTICLE; CONFIDENCE INTERVAL; CONTROLLED STUDY; EMERGENCY WARD; FEMALE; HUMAN; MAJOR CLINICAL STUDY; MALE; MEDICAL EDUCATION; PHYSICIAN; PRIORITY JOURNAL; SENSITIVITY ANALYSIS; STROKE; VOCATIONAL EDUCATION;

ACUTE DISEASE; CONSENSUS; DECISION MAKING; EMERGENCY MEDICAL SERVICES; EMERGENCY MEDICINE; FALSE POSITIVE REACTIONS; FEMALE; FIBRINOLYTIC AGENTS; HUMANS; INJECTIONS, INTRAVENOUS; INTERNSHIP AND RESIDENCY; MALE; MIDDLE AGED; NEUROLOGY; PRACTICE GUIDELINES AS TOPIC; PREDICTIVE VALUE OF TESTS; PROFESSIONAL PRACTICE; PROSPECTIVE STUDIES; RECOMBINANT PROTEINS; SENSITIVITY AND SPECIFICITY; STROKE; THROMBOLYTIC THERAPY; TISSUE PLASMINOGEN ACTIVATOR;

EID: 36949028944     PISSN: 15416933     EISSN: None     Source Type: Journal    
DOI: 10.1007/s12028-007-0065-1     Document Type: Article

References (30)

1. Reed S, Cramer S, Blough D, Meyer K, Jarvik J. Treatment with tissue plasminogen activator and inpatient mortality rates for patients with ischemic stroke treated in community hospitals. Stroke 2001;32:1832-40.
2. Hacke W, Donnan G, Fieschi C, et al. Association of outcome with early stroke treatment: pooled analysis of ATLANTIS, ECASS, and NINDS rt-PA stroke trials. Lancet 2004;363:768-74.
3. Alberts MJ, Hademenos G, Latchaw RE, et al. Recommendations for the establishment of primary stroke centers. Brain Attack Coalition. JAMA 2000;283:3102-9.
4. Gomez CR, Malkoff MD, Sauer CM, Tulyapronchote R, Burch CM, Banet GA. Code stroke. An attempt to shorten inhospital therapeutic delays. Stroke 1994;25:1920-3.
5. Rapp K, Bratina P, Barch C, et al. Code stroke: rapid transport, triage and treatment using rt-PA therapy. The NINDS rt-PA Stroke Study Group. J Neurosci Nurs 1997;29:361-6.
6. Bradley WG. Neurology in the next two decades: report of the Workforce Task Force of the American Academy of Neurology. Neurology 2000;54:787-9.
7. Katzan IL, Sila CA, Furlan AJ. Community use of intravenous tissue plasminogen activator for acute stroke: results of the brain matters stroke management survey. Stroke 2001;32:861-5.
8. Kleindorfer D, Hill MD, Woo D, et al. A description of Canadian and United States physician reimbursement for thrombolytic therapy administration in acute ischemic stroke. Stroke 2005;36:682-7.
9. Brown DL, Barsan WG, Lisabeth LD, Gallery ME, Morgenstern LB. Survey of emergency physicians about recombinant tissue plasminogen activator for acute ischemic stroke. Ann Emerg Med 2005;46:56-60.
10. Kothari RU, Brott T, Broderick JP, Hamilton CA. Emergency physicians : accuracy in the diagnosis of stroke. Stroke 1995;26:2238-41.
11. Morgenstern LB, Lisabeth LD, Mecozzi AC, et al. A population-based study of acute stroke and TIA diagnosis. Neurology 2004;62:895-900.
12. Akins PT, Delemos C, Wentworth D, Byer J, Schorer SJ, Atkinson RP. Can emergency department physicians safely and effectively initiate thrombolysis for acute ischemic stroke? Neurology 2000;55:1801-5.
13. Asimos AW, Norton HJ, Price MF, Cheek WM. Therapeutic yield and outcomes of a community teaching hospital code stroke protocol. Acad Emerg Med 2004;11:361-70.
14. Tanne D, Bates VE, Verro P, et al. Initial clinical experience with IV tissue plasminogen activator for acute ischemic stroke: a multicenter survey. The t-PA Stroke Survey Group. Neurology 1999;53:424-7.
15. Kunnel B, Heller M. Thrombolytics and stroke: what do emergency medicine residents perceive? Acad Emerg Med 1999;6:1174-6.
16. MASCOTS Training Manual. Michigan Acute Stroke Care Overview and Treatment Surveillance System (MASCOTS) "Suspect Stroke" intake form. 2002.
17. Feinstein AR, Cicchetti DV. High agreement but low Kappa: I. the problems of two paradoxes. J Clin Epidemiol 1990;43:543-9.
18. Clopper CJ, Pearson ES. The use of confidence or Fiducial limits illustrated in the case of the binomial. Biometrika 1934;26:404-13.
19. Weintraub MI. Thrombolysis (Tissue Plasminogen Activator) in Stroke: a medicolegal quagmire. Stroke 2006;37:1917-22.
20. Buchan AM, Barber PA, Newcommon N, et al. Effectiveness of t-PA in acute ischemic stroke: outcome relates to appropriateness. Neurology 2000;54:679-84.
21. Lopez-Yunez AM, Bruno A, Williams LS, Yilmaz E, Zurru C, Biller J. Protocol violations in community-based rTPA stroke treatment are associated with symptomatic intracerebral hemorrhage. Stroke 2001;32:12-6.
22. Smith RW, Scott PA, Grant RJ, Chudnofsky CR, Frederiksen SM. Emergency physician treatment of acute stroke with recombinant tissue plasminogen activator: a retrospective analysis. Acad Emerg Med 1999;6:618-25.
23. Barber PA, Zhang J, Demchuk AM, Hill MD, Buchan AM. Why are stroke patients excluded from TPA therapy? An analysis of patient eligibility. Neurology 2001;56:1015-20.
24. Smith EE, Abdullah AR, Petkovska I, Rosenthal E, Koroshetz WJ, Schwamm LH. Poor outcomes in patients who do not receive intravenous tissue plasminogen activator because of mild or improving ischemic stroke. Stroke 2005;36:2497-9.
25. Nor AM, Davis J, Sen B, et al. The Recognition of Stroke in the Emergency Room (ROSIER) scale: development and validation of a stroke recognition instrument. Lancet Neurol 2005;4:727-34.
26. Schwamm LH, Rosenthal ES, Hirshberg A, et al. Virtual Tele-Stroke support for the emergency department evaluation of acute stroke. Acad Emerg Med 2004;11:1193-7.
27. Wang S, Gross H, Lee SB, et al. Remote evaluation of acute ischemic stroke in rural community hospitals in Georgia. Stroke 2004;35:1763-8.
28. A systems approach to immediate evaluation and management of hyperacute stroke. Experience at eight centers and implications for community practice and patient care. The National Institute of Neurological Disorders and Stroke (NINDS) rt-PA Stroke Study Group. Stroke 1997;28:1530-40.
29. California Acute Stroke Pilot Registry (CASPR) Investigators. Prioritizing interventions to improve rates of thrombolysis for ischemic stroke. Neurology 2005;64:654-9.
30. Heuschmann PU, Kolominsky-Rabas PL, Roether J, et al. Predictors of in-hospital mortality in patients with acute ischemic stroke treated with thrombolytic therapy. JAMA 2004;292:1831-8.