Issues in consumer exposure modeling: Towards harmonization on a global scale

Journal of Exposure Science and Environmental Epidemiology

Volumn 17, Issue SUPPL. 1, 2007, Pages

  Kephalopoulos, Stylianos ^a   De Bruin, Yuri Bruinen ^a   Arvanitis, Athanasios ^a   Hakkinen, Pertti ^a,c   Jantunen, Matti ^b  

^a JOINT RESEARCH CENTRE   (Italy)

^b NATIONAL PUBLIC HEALTH INSTITUTE   (Finland)

^c GRADIENT   (United States)

Author keywords

Assessment; Consumer; Frame work; Harmonization; Modeling

Indexed keywords

AWARENESS; CONSUMER HEALTH INFORMATION; EXPOSURE; HEALTH CARE ORGANIZATION; HUMAN; LAW; REVIEW; RISK ASSESSMENT; RISK MANAGEMENT; STATISTICAL ANALYSIS; STATISTICAL MODEL;

CANADA; CHEMICAL INDUSTRY; CONSUMER PRODUCT SAFETY; DECISION MAKING; ENVIRONMENTAL EXPOSURE; EUROPEAN UNION; HEALTH POLICY; HUMANS; INTERNATIONAL COOPERATION; INTERPROFESSIONAL RELATIONS; JAPAN; MODELS, BIOLOGICAL; RISK ASSESSMENT; UNITED STATES;

EID: 36949023546     PISSN: 15590631     EISSN: 1559064X     Source Type: Journal    
DOI: 10.1038/sj.jes.7500605     Document Type: Review

References (16)

1. Bruinen de Bruin Y., Koistinen K., Yli-Tuomi T., Kephalopoulos S., and Jantunen M. A Review of Source Apportionment Techniques and Marker Substances Available for Identification of Personal Exposure, Indoor and Outdoor Sources of Chemicals. Office for Official Publication of the European Communities, Luxembourg. EUR 22349 EN, 2006.
2. Council of the European Union, REACH Regulation (EC) No. 1907/2006 of the European Parliament and of the Council, 18 December 2006. 2006.
3. Global Consumer Exposure Models Net database (http://cem.jrc.it/cemdb/ qstart.php), Commission of the European Communities, Joint Research Centre, Institute for Health and Consumer Protection, Physical & Chemical Exposure Unit, 2004.
4. Global CEM Net. Global Net on "Consumer Exposure Modeling". In: Kephalopoulos S., van Hemmen J., and van der Jagt K. (Eds.). Workshop no. 1 report on "Dermal Transfer and Penetration algorithms", 20-21 June 2005, Intra (Italy), Office for Official Publication of the European Communities, Luxembourg. EUR 22521 EN/1, 2006a.
5. Global CEM Net. Global Net on "Consumer Exposure Modeling". In: Kephalopoulos S., Arvanitis A., and Jayjock M. (Eds.). Workshop no. 2 report on "Source characterization, transport and fate", 20-21 June 2005, Intra (Italy), Office for Official Publication of the European Communities, Luxembourg. EUR 22521 EN/2, 2006b.
6. Global CEM Net. Global Net on "Consumer Exposure Modeling". In: Kephalopoulos S., Arvanitis A., and Jantunen M. (Eds.). Workshop no. 3 report on "Exposure Modelling Framework Issues", 22 June 2005, Intra (Italy), Office for Official Publication of the European Communities, Luxembourg. EUR 22521 EN/3, 2006c.
7. Global CEM Net. Global Net on "Consumer Exposure Modeling". In: Kephalopoulos, Money C., Price P., and van Engelen J. (Eds.). Workshop no. 4 report on "Exposure related data", 23 June 2005, Intra (Italy), Office for Official Publication of the European Communities, Luxembourg. EUR 22521 EN/4, 2006d.
8. Global CEM Net. Global Net on "Consumer Exposure Modeling". In: Kephalopoulos S., Arvanitis A., and van Engelen J. (Eds.) Workshop no. 5 report on "Exposure scenarios", 24 June 2005, Intra (Italy), Office for Official Publication of the European Communities, Luxembourg. EUR 22521 EN/5, 2006e.
9. Netzeva T.I., Worth A.P., Aldenberg T., Benigni R., Cronin M.T.D., Gramatica P., Jaworska J.S., Klopman G., Marchant C.A., Myatt G., Nikolova-Jeliazkova N., Patlewicz G.Y., Perkins R., Roberts D.W., Schultz T.W., Stanton D.T., van de Sandt J.J.M., Tong W., Veith G., and Yang C. Current status of methods for defining the applicability domain of (quantitative) structure-activity relationships. The report and recommendations of ECVAM Workshop 52. Altern Lab Anim 2005: 33: 152-173.
10. Potts R.O., and Guy R.H. Predicting skin permeability. Pharm Res 1992: 9: 663-669.
11. US EPA. Human Health Research Strategy, Washington, DC, US EPA, Office of Research and Development (EPA/600/R-02/050), 2003.
12. van de Sandt J.M., Dellarco M., and van Hemmen J. From dermal exposure to internal dose. J Expo Sci Environ Epidemiol 2007, Advance online publication 18 April 2007; doi: 10.1038/sj.jes.7500759.
13. Vuori V., Zaleski R.T., and Jantunen M.J. ExpoFacts - an overview of European Exposure Factors Data. Risk Anal 2006: 26(3): 831-843.
14. WHO International Programme on Chemical Safety. IPCS risk assessment terminology. 2 pts. in 1 v. - (IPCS harmonization project; document no. 1) Contents: Pt. 1, IPCS/OECD key generic terms used in chemical hazard/risk assessment/International Programme on Chemical Safety Joint Project with OECD on the harmonization of hazard/risk assessment terminology - Pt. 2, IPCS glossary of key exposure assessment terminology/IPCS project on the harmonization of approaches to the assessment of risk from exposure to chemicals, WHO, Geneva, 2004, 122 pp.
15. WHO International Programme on Chemical Safety. Principles of characterizing and applying human exposure models. (IPCS harmonization project document; no. 3), WHO, Geneva 2005, 76 pp.
16. WHO International Programme on Chemical Safety. Guidance document on "Characterizing and Communicating Uncertainty in Exposure Assessment", http://www.who.int/ipcs/methods/harmonization/areas/ exposure/en/index.html, 2006.