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Volumn 26, Issue 6-7, 2007, Pages 865-868

RNAi activity of siRNAs modified with 2′-aminoalkyl-substituted fluorinated nucleobases

Author keywords

2 modification; RNAi; siRNA; Universal nucleosides

Indexed keywords

1' DEOXY 1' (4,6 DIFLUORO 1H BENZIMIDAZOL 1 YL) 2' (BETA AMINOETHYL) BETA DEXTRO RIBOFURANOSE NUCLEOSIDE; ALKYL GROUP; GREEN FLUORESCENT PROTEIN; NUCLEIC ACID BASE; NUCLEOSIDE ANALOG; SMALL INTERFERING RNA; UNCLASSIFIED DRUG;

EID: 36949015181     PISSN: 15257770     EISSN: 15322335     Source Type: Journal    
DOI: 10.1080/15257770701504033     Document Type: Conference Paper
Times cited : (3)

References (6)
  • 1
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    • Synthesis of 2′-aminoalkyl substituted fluorinated nucleobases and their influence on the kinetic properties of hammerhead ribozymes
    • Klöpffer, A.E.; Engels, J.W. Synthesis of 2′-aminoalkyl substituted fluorinated nucleobases and their influence on the kinetic properties of hammerhead ribozymes. ChemBioChem 2004, 5, 100-109.
    • (2004) ChemBioChem , vol.5 , pp. 100-109
    • Klöpffer, A.E.1    Engels, J.W.2
  • 2
    • 0142124143 scopus 로고    scopus 로고
    • Human immunodeficiency virus type 1 escape from RNA interference
    • Boden, D.; Pusch, O.; Lee, F.; Tucker, L.; Ramratnam, B. Human immunodeficiency virus type 1 escape from RNA interference. J. Virol. 2003, 77, 11531-11535.
    • (2003) J. Virol , vol.77 , pp. 11531-11535
    • Boden, D.1    Pusch, O.2    Lee, F.3    Tucker, L.4    Ramratnam, B.5
  • 3
    • 13844320402 scopus 로고    scopus 로고
    • HIV-1 can escape from RNA interference by evolving an alternative structure in its RNA genome
    • Westerhout, E.M.; Ooms, M.; Vink, M.; Das A.; Berkhout, B. HIV-1 can escape from RNA interference by evolving an alternative structure in its RNA genome. Nucleic Acids Res. 2005, 33, 796-804.
    • (2005) Nucleic Acids Res , vol.33 , pp. 796-804
    • Westerhout, E.M.1    Ooms, M.2    Vink, M.3    Das, A.4    Berkhout, B.5
  • 4
    • 0041331496 scopus 로고    scopus 로고
    • Chiu Y.; Rana, T. siRNA function in RNAi: A chemical modification analysis. RNA 2003, 9, 1034-1048.
    • Chiu Y.; Rana, T. siRNA function in RNAi: A chemical modification analysis. RNA 2003, 9, 1034-1048.
  • 5
    • 0036323162 scopus 로고    scopus 로고
    • Gene transduction efficiency in cells of different species by HIV and EIAV vectors
    • Ikeda, Y.; Collins, M.K.L.; Radcliffe, P.A.; Mitrophanous, K.A.; Takeuchi, Y. Gene transduction efficiency in cells of different species by HIV and EIAV vectors. Gene Ther. 2002, 9, 932-938.
    • (2002) Gene Ther , vol.9 , pp. 932-938
    • Ikeda, Y.1    Collins, M.K.L.2    Radcliffe, P.A.3    Mitrophanous, K.A.4    Takeuchi, Y.5
  • 6
    • 15044358407 scopus 로고    scopus 로고
    • A systematic analysis of the silencing effects of an active siRNA at all single-nucleotide mismatched target sites
    • Du, Q.; Thonberg, H.; Wang, J.; Wahlestedt, C.; Liang, Z. A systematic analysis of the silencing effects of an active siRNA at all single-nucleotide mismatched target sites. Nucleic Acids Res. 2005, 33, 1671-1677.
    • (2005) Nucleic Acids Res , vol.33 , pp. 1671-1677
    • Du, Q.1    Thonberg, H.2    Wang, J.3    Wahlestedt, C.4    Liang, Z.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.