-
1
-
-
0028351583
-
Specific motifs recognized by the SH2 domains of Csk, 3BP2, fps/fes, GRB-2, HCP, SHC, Syk, and Vav
-
Songyang Z, Shoelson SE, McGlade J et al (1994) Specific motifs recognized by the SH2 domains of Csk, 3BP2, fps/fes, GRB-2, HCP, SHC, Syk, and Vav. Mol Cell Biol 14:2777-2785
-
(1994)
Mol Cell Biol
, vol.14
, pp. 2777-2785
-
-
Songyang, Z.1
Shoelson, S.E.2
McGlade, J.3
-
2
-
-
0034668178
-
Inhibitors of Ras signal transduction as antitumor agents
-
Garbay C, Liu WQ, Vidal M et al (1994) Inhibitors of Ras signal transduction as antitumor agents. Biochem Pharmacol 60:1165-1169
-
(1994)
Biochem Pharmacol
, vol.60
, pp. 1165-1169
-
-
Garbay, C.1
Liu, W.Q.2
Vidal, M.3
-
3
-
-
0030849128
-
The Role of Grb2-associated proteins in T-cell activation
-
Koretzky GA (1997) The Role of Grb2-associated proteins in T-cell activation. Immunol Today 18:401-406
-
(1997)
Immunol Today
, vol.18
, pp. 401-406
-
-
Koretzky, G.A.1
-
4
-
-
0028897659
-
Regulation of the adapter molecule Grb2 by the Fc-Epsilon-R1 in the Mast-Cell Line Rbl2H3
-
Turner H, Reif K, Rivera J et al (1995) Regulation of the adapter molecule Grb2 by the Fc-Epsilon-R1 in the Mast-Cell Line Rbl2H3. J Biol Chem 270:9500-9506
-
(1995)
J Biol Chem
, vol.270
, pp. 9500-9506
-
-
Turner, H.1
Reif, K.2
Rivera, J.3
-
5
-
-
10344244510
-
Structural aspects of signal-transduction in B-Cells
-
Vihinen M, Smith CIE (1996) Structural aspects of signal-transduction in B-Cells. Crit Rev Immunol 16:251-275
-
(1996)
Crit Rev Immunol
, vol.16
, pp. 251-275
-
-
Vihinen, M.1
Smith, C.I.E.2
-
6
-
-
0028609382
-
Integrin-mediated signal transduction linked to Ras pathway by GRB2 binding to focal adhesion kinase
-
Schlaepfer DD, Hanks SK, Hunter T et al (1994) Integrin-mediated signal transduction linked to Ras pathway by GRB2 binding to focal adhesion kinase. Nature 372:786-791
-
(1994)
Nature
, vol.372
, pp. 786-791
-
-
Schlaepfer, D.D.1
Hanks, S.K.2
Hunter, T.3
-
7
-
-
0033007901
-
Membrane-targeting of signalling molecules by SH2/SH3 domain containing adaptor proteins
-
Buday L (1999) Membrane-targeting of signalling molecules by SH2/SH3 domain containing adaptor proteins. Biochim Biophys Acta 1422:187-204
-
(1999)
Biochim Biophys Acta
, vol.1422
, pp. 187-204
-
-
Buday, L.1
-
8
-
-
0037318720
-
Adaptors as central mediators of signal transduction in immune cells
-
Jordan MS, Singer AL, Koretzky GA (2003) Adaptors as central mediators of signal transduction in immune cells. Nat Immunol 4:110-116
-
(2003)
Nat Immunol
, vol.4
, pp. 110-116
-
-
Jordan, M.S.1
Singer, A.L.2
Koretzky, G.A.3
-
9
-
-
0035936696
-
Solution structure of Grb2 reveals extensive flexibility necessary for target recognition
-
Yuzawa S, Yokochi M, Hatanaka H et al (2001) Solution structure of Grb2 reveals extensive flexibility necessary for target recognition. J Mol Biol 306:527-537
-
(2001)
J Mol Biol
, vol.306
, pp. 527-537
-
-
Yuzawa, S.1
Yokochi, M.2
Hatanaka, H.3
-
10
-
-
33745204479
-
AMP-activated protein kinase integrates nutrient and hormonal signals to regulate food intake and energy balance through effects in the hypothalamus and peripheral tissues
-
Xue B, Kahn BB (2006) AMP-activated protein kinase integrates nutrient and hormonal signals to regulate food intake and energy balance through effects in the hypothalamus and peripheral tissues. J Physiol 574:73-83
-
(2006)
J Physiol
, vol.574
, pp. 73-83
-
-
Xue, B.1
Kahn, B.B.2
-
11
-
-
0038814313
-
A novel domain in AMP-activated protein kinase causes glycogen storage bodies similar to those seen in hereditary cardiac arrhythmias
-
Hudson ER, Pan DA, James J et al (2003) A novel domain in AMP-activated protein kinase causes glycogen storage bodies similar to those seen in hereditary cardiac arrhythmias. Curr Biol 13:861-866
-
(2003)
Curr Biol
, vol.13
, pp. 861-866
-
-
Hudson, E.R.1
Pan, D.A.2
James, J.3
-
12
-
-
33846030181
-
A revised model for AMP-activated protein kinase structure: The alpha-subunit binds to both the beta- and gamma-subunits although there is no direct binding between the beta- and gamma-subunits
-
Wong KA, Lodish HF (2006) A revised model for AMP-activated protein kinase structure: The alpha-subunit binds to both the beta- and gamma-subunits although there is no direct binding between the beta- and gamma-subunits. J Biol Chem 281:36434-36442
-
(2006)
J Biol Chem
, vol.281
, pp. 36434-36442
-
-
Wong, K.A.1
Lodish, H.F.2
-
13
-
-
22244459572
-
Monitoring energy balance: Metabolites of fatty acid synthesis as hypothalamic sensors
-
Dowell P, Hu Z, Lane MD (2005) Monitoring energy balance: Metabolites of fatty acid synthesis as hypothalamic sensors. Annu Rev Biochem 74:515-534
-
(2005)
Annu Rev Biochem
, vol.74
, pp. 515-534
-
-
Dowell, P.1
Hu, Z.2
Lane, M.D.3
-
14
-
-
20844451123
-
AMP-activated protein kinase: Ancient energy gauge provides clues to modern understanding of metabolism
-
Kahn BB, Alquier T, Carling D et al (2005) AMP-activated protein kinase: ancient energy gauge provides clues to modern understanding of metabolism. Cell Metab 1:15-25
-
(2005)
Cell Metab
, vol.1
, pp. 15-25
-
-
Kahn, B.B.1
Alquier, T.2
Carling, D.3
-
15
-
-
2442631468
-
C75, a fatty acid synthase inhibitor, reduces food intake via hypothalamic AMP-activated protein kinase
-
Kim EK, Miller I, Aja S et al (2004) C75, a fatty acid synthase inhibitor, reduces food intake via hypothalamic AMP-activated protein kinase. J Biol Chem 279:19970-19976
-
(2004)
J Biol Chem
, vol.279
, pp. 19970-19976
-
-
Kim, E.K.1
Miller, I.2
Aja, S.3
-
16
-
-
3142677140
-
Anti-obesity effects of α-lipoic acid mediated by suppression of hypothalamic AMP-activated protein kinase
-
Kim MS, Park JY, Namkoong C et al (2004) Anti-obesity effects of α-lipoic acid mediated by suppression of hypothalamic AMP-activated protein kinase. Nat Med 10:727-733
-
(2004)
Nat Med
, vol.10
, pp. 727-733
-
-
Kim, M.S.1
Park, J.Y.2
Namkoong, C.3
-
17
-
-
1842582870
-
AMP-activated protein kinase plays a role in the control of food intake
-
Andersson U, Filipsson K, Abbott CR et al. (2004) AMP-activated protein kinase plays a role in the control of food intake. J Biol Chem 279:12005-12008
-
(2004)
J Biol Chem
, vol.279
, pp. 12005-12008
-
-
Andersson, U.1
Filipsson, K.2
Abbott, C.R.3
-
18
-
-
0037122766
-
Leptin stimulates fatty-acid oxidation by activating AMP-activated protein kinase
-
Minokoshi Y, Kim YB, Peroni OD et al (2002) Leptin stimulates fatty-acid oxidation by activating AMP-activated protein kinase. Nature 415:339-343
-
(2002)
Nature
, vol.415
, pp. 339-343
-
-
Minokoshi, Y.1
Kim, Y.B.2
Peroni, O.D.3
-
19
-
-
26244461692
-
Hypothalamic AMP-activated protein kinase mediates counter-regulatory responses to hypoglycaemia in rats
-
Han SM, Namkoong C, Jang PG et al (2005) Hypothalamic AMP-activated protein kinase mediates counter-regulatory responses to hypoglycaemia in rats. Diabetologia 48:2170-2178
-
(2005)
Diabetologia
, vol.48
, pp. 2170-2178
-
-
Han, S.M.1
Namkoong, C.2
Jang, P.G.3
-
20
-
-
21644453934
-
Cannabinoids and ghrelin have both central and peripheral metabolic and cardiac effects via AMP-activated protein kinase
-
Kola B, Hubina E, Tucci SA et al (2005) Cannabinoids and ghrelin have both central and peripheral metabolic and cardiac effects via AMP-activated protein kinase. J Biol Chem 280:25196-25201
-
(2005)
J Biol Chem
, vol.280
, pp. 25196-25201
-
-
Kola, B.1
Hubina, E.2
Tucci, S.A.3
-
21
-
-
0029910018
-
Characterization of the AMP-activated protein kinase from rat liver and identification of threonine 172 as the major site at which it phosphorylates AMP-activated protein kinase
-
Hawley SA, Davison M, Woods A et al (1996) Characterization of the AMP-activated protein kinase from rat liver and identification of threonine 172 as the major site at which it phosphorylates AMP-activated protein kinase. J Biol Chem 271:27879-27887
-
(1996)
J Biol Chem
, vol.271
, pp. 27879-27887
-
-
Hawley, S.A.1
Davison, M.2
Woods, A.3
-
22
-
-
0041305909
-
Activation of yeast Snf1 and mammalian AMP-activated protein kinase by upstream kinases
-
Hong SP, Leiper FC, Woods A et al (2003) Activation of yeast Snf1 and mammalian AMP-activated protein kinase by upstream kinases. Proc Natl Acad Aci USA 100:8839-8843
-
(2003)
Proc Natl Acad Aci USA
, vol.100
, pp. 8839-8843
-
-
Hong, S.P.1
Leiper, F.C.2
Woods, A.3
-
23
-
-
0041700137
-
Elm1p is one of three upstream kinases for the Saccharomyces cerevisiae SNF1 complex
-
Sutherland CM, Hawley SA, McCartney RR et al (2003) Elm1p is one of three upstream kinases for the Saccharomyces cerevisiae SNF1 complex. Curr Biol 13:1299-1305
-
(2003)
Curr Biol
, vol.13
, pp. 1299-1305
-
-
Sutherland, C.M.1
Hawley, S.A.2
McCartney, R.R.3
-
24
-
-
0345167800
-
TSC2 mediates cellular energy response to control cell growth and survival
-
Inoki K, Zhu T, Guan KL (2003) TSC2 mediates cellular energy response to control cell growth and survival. cell 115:577-590
-
(2003)
Cell
, vol.115
, pp. 577-590
-
-
Inoki, K.1
Zhu, T.2
Guan, K.L.3
-
25
-
-
0036712905
-
Tsc tumour suppressor proteins antagonize amino-acid-TOR signalling
-
Gao X, Zhang Y, Arrazola P etal (2002) Tsc tumour suppressor proteins antagonize amino-acid-TOR signalling. Nat Cell Biol 4:699-704
-
(2002)
Nat Cell Biol
, vol.4
, pp. 699-704
-
-
Gao, X.1
Zhang, Y.2
Arrazola, P.3
-
26
-
-
0037121923
-
PDK1-dependent activation of atypical PKC leads to degradation of the p21 tumour modifier protein
-
Scott MT, Ingram A, Ball KL (2002) PDK1-dependent activation of atypical PKC leads to degradation of the p21 tumour modifier protein. EMBO J 21:6771-6780
-
(2002)
EMBO J
, vol.21
, pp. 6771-6780
-
-
Scott, M.T.1
Ingram, A.2
Ball, K.L.3
-
27
-
-
0037339887
-
Grb2 regulates internalization of EGF receptors through clathrin-coated pits
-
Jiang X, Huang F, Marusyk A et al (2003) Grb2 regulates internalization of EGF receptors through clathrin-coated pits. Mol Biol Cell 14:858-870
-
(2003)
Mol Biol Cell
, vol.14
, pp. 858-870
-
-
Jiang, X.1
Huang, F.2
Marusyk, A.3
-
28
-
-
0035161915
-
GRB2: A pivotal protein in signal transduction
-
Tari AM, Lopez-Berestein G (2001) GRB2: A pivotal protein in signal transduction. Semin Oncol 28:142-147
-
(2001)
Semin Oncol
, vol.28
, pp. 142-147
-
-
Tari, A.M.1
Lopez-Berestein, G.2
-
29
-
-
10944247187
-
The AMP-activated protein kinase pathway players upstream and downstream
-
Hardie DG (2004) The AMP-activated protein kinase pathway players upstream and downstream. J Cell Science 117:5479-5487
-
(2004)
J Cell Science
, vol.117
, pp. 5479-5487
-
-
Hardie, D.G.1
-
30
-
-
0346463030
-
Adiponectin stimulates angiogenesis by promoting cross-talk between AMPactivated protein kinase and Akt signaling in endothelial cells
-
Ouchi N, Kobayashi H, Kihara S (2004). Adiponectin stimulates angiogenesis by promoting cross-talk between AMPactivated protein kinase and Akt signaling in endothelial cells. J Biol Chem 279:1304-1309
-
(2004)
J Biol Chem
, vol.279
, pp. 1304-1309
-
-
Ouchi, N.1
Kobayashi, H.2
Kihara, S.3
-
31
-
-
34248194200
-
The regulation of AMPK beta1, TSC2, and PTEN expression by p53: Stress, cell and tissue specificity, and the role of these gene products in modulating the IGF-1-AKT-mTOR pathways
-
Feng Z, Hu W, de Stanchina E et al (2007) The regulation of AMPK beta1, TSC2, and PTEN expression by p53: Stress, cell and tissue specificity, and the role of these gene products in modulating the IGF-1-AKT-mTOR pathways. Cancer Res 67:3043-3053
-
(2007)
Cancer Res
, vol.67
, pp. 3043-3053
-
-
Feng, Z.1
Hu, W.2
de Stanchina, E.3
-
32
-
-
25444524850
-
Akt activates mTOR by regulating cellular ATP level and AMPK activity
-
Hahn-Windgassen A, Nogueira V, Chen CC et al (2005) Akt activates mTOR by regulating cellular ATP level and AMPK activity. J Biol Chem 280:32081-32089
-
(2005)
J Biol Chem
, vol.280
, pp. 32081-32089
-
-
Hahn-Windgassen, A.1
Nogueira, V.2
Chen, C.C.3
|