Effects of Astragalus polysaccharides on chymase, angiotensin-converting enzyme and angiotensin II in diabetic cardiomyopathy in hamsters

Journal of International Medical Research

Volumn 35, Issue 6, 2007, Pages 873-877

  Chen, Wei ^a   Li, Yi Ming ^a   Yu, Mao Hua ^a  

^a FUDAN UNIVERSITY   (China)

Author keywords

Angiotensin II; Angiotensin converting enzyme; Astragalus polysaccharides; Chymase; Diabetic cardiomyopathy

Indexed keywords

ANGIOTENSIN II; ASTRAGALUS MEMBRANACEUS EXTRACT; C PEPTIDE; CHYMASE; DIPEPTIDYL CARBOXYPEPTIDASE; INSULIN; POLYSACCHARIDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CARDIOMYOPATHY; CONTROLLED STUDY; DIABETES MELLITUS; DOWN REGULATION; DRUG MECHANISM; ENZYME ACTIVITY; ENZYME INHIBITION; GENE EXPRESSION; HAMSTER; INSULIN BLOOD LEVEL; NONHUMAN; PROTEIN BLOOD LEVEL;

EID: 36949005202     PISSN: 03000605     EISSN: None     Source Type: Journal    
DOI: 10.1177/147323000703500615     Document Type: Article

References (12)

1. Cong L, Li Y-M, Yu M-H, et al: Effect of Astragalus polysaccharides on the expression of myocardial collagen in hamsters with diabetic cardiomyopathy. Chin J Clin Rehabil 2006; 10: 64-66.
2. Ni Y, Su Q, Liu X, et al: Experimental study of optimized techniques of water decoction extraction of Astragalus polysaccharide. Zhongguo Zhong Yao Za Zhi 1998; 23: 284-286.
3. Takai S, Sakaguchi M, Jin D, et al: Different angiotensin II-forming pathways in human and rat vascular tissues. Clin Chim Acta 2001; 305: 191-205.
4. Takai S, Miyazaki M: The role of chymase in vascular proliferation. Drug News Perspect 2002; 15: 278-282.
5. Miyazaki M, Takai S: Local angiotensin II-generating system in vascular tissues: the roles of chymase. Hypertens Res 2001; 24: 189-193.
6. Jin D, Takai S, Yamada M, et al: Possible roles of cardiac chymase after myocardial infarction in hamster hearts. Jpn J Pharmacol 2001; 86: 203-214.
7. Jin D, Takai S, Yamada M, et al: The functional ratio of chymase and angiotensin converting enzyme in angiotensin I-induced vascular contraction in monkeys, dogs and rats. Jpn J Pharmacol 2000; 84: 449-454.
8. Urata H, Ganten D: Cardiac angiotensin II formation: the angiotensin-I converting enzyme and human chymase. Eur Heart J 1998; 14(suppl I): 177-182.
9. Chen W, Yu M-H, Li Y-M: Effects of Astragalus polysaccharides on ultrastructure and oxidation/apoptosis related cytokines' gene expression of NOD mice islets. Fudan Univ J Med Sci 2007; 34: 269-272.
10. Chen W, Xia Y-P, Yu M-H: Astragalus polysaccharides effect on pancreatic histopathology. Chin J Modern Med 2007; 17: 146-148.
11. Chen W, Li Y-M, Yu M-H, et al: Immunoregulation effects of Astragalus polysaccharides on T helper lymphocyte subgroups in nonobese diabetic mice. Chin J Modern Med 2007; 17: 28-31.
12. Chen W, Yu M-H: Effects of Astragalus polysaccharide on gene expression profiles in islets of NOD mice with microarray technique. Chin J Endocrinol Metab 2004; 20: 545-548.