Insulin requirement in patients with type 1 diabetes with reduced renal function: A comparison of human and analogue insulin;Insulinbedarf bei typ-1-diabetikern mit nachlassender nierenfunktion: Human-insulin versus analog-insulin

Deutsche Medizinische Wochenschrift

Volumn 132, Issue 47, 2007, Pages 2500-2504

  Hasslacher, Christoph ^a,c   Vogt, C ^a   Raupp, D ^a   Dreyhaupt, J ^b  

^a UNIVERSITY HOSPITAL HEIDELBERG   (Germany)

^b UNIVERSITY OF HEIDELBERG   (Germany)

^c StJosefs Krankenhaus Heidelberg   (Germany)

Author keywords

Diabetes mellitus; Diabetic nephropathy; Human insulin, analogue insuline; Insulin requirement; Renal insufficiency

Indexed keywords

ANTIHYPERTENSIVE AGENT; ASPART; GLARGIN; GLUSILIN; HUMAN INSULIN; INSULIN DERIVATIVE; INSULIN DETEMIR; INSULIN GLARGINE; INSULIN LISPRO; ORAL ANTIDIABETIC AGENT; UNCLASSIFIED DRUG;

ARTICLE; CONTROLLED STUDY; CREATININE CLEARANCE; DEMOGRAPHY; DIABETIC NEPHROPATHY; FEMALE; HUMAN; HYPERTENSION; INSULIN CLEARANCE; INSULIN DEPENDENT DIABETES MELLITUS; KIDNEY DYSFUNCTION; KIDNEY FAILURE; KIDNEY FUNCTION; LINEAR REGRESSION ANALYSIS; MAJOR CLINICAL STUDY; MALE; METABOLIC REGULATION; PREVALENCE; RETROSPECTIVE STUDY;

CREATININE; DIABETES MELLITUS, TYPE 1; DIABETIC NEPHROPATHIES; FEMALE; HUMANS; HYPERTENSION; HYPOGLYCEMIC AGENTS; INSULIN; KIDNEY; KIDNEY FUNCTION TESTS; LINEAR MODELS; MALE; METABOLIC CLEARANCE RATE; MIDDLE AGED; RENAL INSUFFICIENCY; RETROSPECTIVE STUDIES;

EID: 36849091487     PISSN: 00120472     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-2007-993090     Document Type: Article

References (16)

1. Alvestrand A. Carbohydrate and insulin metabolism in renal failure. Kidney Int 1997; 52, Suppt 62: 48-52
2. Charlesworth JA, Kriketos AD, Jones JE, Erlich JH, Campell LV, Peake PW. Insulin resistance and postprandial triglyceride levels in primary renal disease. Metabolism Clinical and Experimental 2005; 54: 821-828
3. Cryer PE. Hypoglycaemia is the limiting factor in the management of diabetes. Diabetes Metab Res Rev 1999; 15: 42-46
4. Fliser D, Pacini G, Engelleiter R et al. Insulin resistance and hyperinsulinemia are already present in patients with incipient renal disease. Kidney Int 1998; 53: 1343-1347
5. De Fronzo RA, Alvestrand A. Glucose intolerance in uremia: Site and mechanism. Am J Clin Nutr 1980; 3: 1438-1445
6. Hasslacher C, Wittmann W. Schwere Hypoglykämien bei Diabetikern mit eingeschränkter Nierenfunktion. Dtsch Med Wochenschr 2003; 128: 253-256
7. Homes G, Galitz L, Hu P, Lyness W. Pharmacokinetics of insulin aspart in obesity, renal impairment, or hepatic impairment. Br J Clin Pharmacol 2005; 60,5: 469-476
8. www.lantus-studiencenter.de
9. Manto A, Cotroneo P, Marra G et al. Effect of intensive treatment on diabetic nephropathy in patients with type I diabetes. Kidney Int 1995; 47: 231-235
10. Morioka T, Emoto M, Tabata T et al. Glycemic control is a predictor of survival for diabetic patients on hemodialysis. Diabetes Care 2001; 24: 909-913
11. Rabkin R, Ryan MP, Duckworth WC. The renal metabolism of insulin. Diabetologia 1984; 27: 351-357
12. Rave K, Heise T, Pfützner A, Heinemann L, Sawicki PT. Impact of diabetic nephropathy on pharmacodynamic and pharmacokinetic properties of insulin in type 1 diabetic patients. Diab Care 2001; 24: 886-890
13. Rosenkranz R, Profozic V, Metelko Z, Mrzljak V, Lange C, Malerczyk V. Pharmacokinetics and safety of glimepiride at clinically effective doses in diabetic patients with renal impairment. Diabetologia 1996; 39: 1617-1624
14. Rubenstein AH, Mako ME, Horwitz DL. Insulin and the kidney. Nephron 1975; 15: 306-326
15. Svensson M, Yu ZW, Eriksson JW. A small reduction in glomerular filtration is accompanied by insulin resistance in type I diabetes patients with diabetic nephropathy. Eur J Clin Invest 2002; 32: 100-109
16. Vogt C, Dreyhaupt J, Hasslacher C. Einfluß der nachlassenden Nierenfunktion auf die Insulindosis bei Typ 1- und Typ 2-Diabetikern. Diabetologie 2006; 1: 311-318