Population pharmacokinetics and proton pump inhibitory effects of intravenous lansoprazole in healthy Japanese males

Biological and Pharmaceutical Bulletin

Volumn 30, Issue 12, 2007, Pages 2238-2243

  Sakurai, Yuichi ^a,b   Hirayama, Masashi ^b   Hashimoto, Muneaki ^b   Tanaka, Takanori ^c   Hasegawa, Setsuo ^d   Irie, Shin ^e   Ashida, Kiyoshi ^f   Kayano, Yuichiro ^a   Taguchi, Masato ^a   Hashimoto, Yukiya ^a  

^a UNIVERSITY OF TOYAMA   (Japan)

^b TAKEDA PHARMACEUTICAL COMPANY LIMITED   (Japan)

^c Ohsaki Clinic   (Japan)

^d Sekino Clinical Pharmacology Clinic   (Japan)

^e Kyushu Clinical Pharmacology Research Clinic   (Japan)

^f SAISEIKAI NAKATSU HOSPITAL   (Japan)

Author keywords

CYP2C19; Healthy Japanese subject; Lansoprazole; Population pharmacokinetics

Indexed keywords

CYTOCHROME P450 2C19; LANSOPRAZOLE; PROTON PUMP INHIBITOR;

ADULT; ARTICLE; COMPARTMENT MODEL; CONTROLLED STUDY; DRUG HALF LIFE; GASTRIC PH MONITORING; HUMAN; HUMAN EXPERIMENT; MALE; NORMAL HUMAN; POPULATION DYNAMICS; SINGLE DRUG DOSE; STATISTICAL SIGNIFICANCE;

2-PYRIDINYLMETHYLSULFINYLBENZIMIDAZOLES; ADULT; ALGORITHMS; ARYL HYDROCARBON HYDROXYLASES; HALF-LIFE; HUMANS; HYDROGEN-ION CONCENTRATION; INJECTIONS, INTRAVENOUS; JAPAN; MALE; MIXED FUNCTION OXYGENASES; NONLINEAR DYNAMICS; POLYMORPHISM, GENETIC; POPULATION; PROTON PUMP INHIBITORS; REFERENCE VALUES;

EID: 36849090564     PISSN: 09186158     EISSN: 13475215     Source Type: Journal    
DOI: 10.1248/bpb.30.2238     Document Type: Article

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