Modulatory effects of EPA and DHA on proliferation and apoptosis of pancreatic cancer cells

Journal of Huazhong University of Science and Technology - Medical Science

Volumn 27, Issue 5, 2007, Pages 547-550

  Zhang, Weikang ^a   Long, Yueping ^a   Zhang, Jinghui ^a   Wang, Chunyou ^a  

^a HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

Author keywords

3 fatty acid; Apoptosis; Cyclin E; Malignant tumor

Indexed keywords

CYCLIN E; DOCOSAHEXAENOIC ACID; ICOSAPENTAENOIC ACID; MESSENGER RNA;

APOPTOSIS; ARTICLE; CELL PROLIFERATION; DRUG EFFECT; GENETICS; HUMAN; METABOLISM; PANCREAS TUMOR; PATHOLOGY; TUMOR CELL LINE;

APOPTOSIS; CELL LINE, TUMOR; CELL PROLIFERATION; CYCLIN E; DOCOSAHEXAENOIC ACIDS; EICOSAPENTAENOIC ACID; HUMANS; PANCREATIC NEOPLASMS; RNA, MESSENGER;

EID: 36849087895     PISSN: 16720733     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11596-007-0518-y     Document Type: Article

References (10)

1. Fernandez E, Gallus S, La Vecchia C et al. Nutrition and cancer risk: an overview. J Br Menopause Soc, 2006,12(4):139-142
2. Tanaka H, Kageyama K, Kimura M et al. Promotive effects of hyperthermia on the inhibition of DNA synthesis in ehrlich ascites tumor cells by eicosapentaenoic and docosahexaenoic acids. Exp Oncol, 2006,28(3):203-208
3. Tsekos E, Reuter C, Stehle P et al. Perioperative administration of parenteral fish oil supplements in a routine clinical setting improves patient outcome after major abdominal surgery. Clin Nutr, 2004,23(3):325-330
4. Ding W Q, Lind S E. Phospholipid hydroperoxide glutathione peroxidase plays a role in protecting cancer cells from docosahexaenoic acid-induced cytotoxicity. Mol Cancer Ther, 2007,6(4):1467-1474
5. Aleem E, Kiyokawa H, Kaldis P et al. Cdc2-cyclin E complexes regulate the G1/S phase transition. Nat Cell Biol, 2005,7(8):831-836
6. Lundberg A S, Weiberg R A. Functional inactivation of the retinoblastoma protein requires sequential modification by at least two distinct cyclin-cdk complexes. Mol Cell Biol, 1998, 18(11):753-762
7. Rosen D G, Yang G, Deavers M T et al. Cyclin E expression is correlated with tumor progression and predicts a poor prognosis in patients with ovarian carcinoma. Cancer, 2006, 106(9):1925-1932
8. Skalicky D A, Kench J G, Segara D et al. Cyclin E expression and outcome in pancreatic ductal adenocarcinoma. Cancer Epidemiol Biomarkers Prev, 2006,15(10): 1941-1947
9. Hardman W E. (n-3) fatty acids and cancer therapy. J Nutr, 2004,134(12 Suppl):3427S-3430S
10. Danbara N, Yuri T, Tsujita-Kyutoku M et al. Conjugated docosahexaenoic acid is a potent inducer of cell cycle arrest and apoptosis and inhibits growth of colo 201 human colon cancer cells. Nutr Cancer, 2004,50(1):71-79