Investigation of racemisation of the enantiomers of glitazone drug compounds at different pH using chiral HPLC and chiral CE

Journal of Pharmaceutical and Biomedical Analysis

Volumn 46, Issue 1, 2008, Pages 82-87

  Jamali, Babak ^a   Bjørnsdottir, Inga ^a   Nordfang, Ole ^a   Hansen, Steen Honoré ^b  

^a NOVO NORDISK A S   (Denmark)

^b UNIVERSITY OF COPENHAGEN   (Denmark)

Author keywords

Chiral separation; pH; Pioglitazone; Racemisation; Rosiglitazone

Indexed keywords

GLITAZONE DERIVATIVE; PIOGLITAZONE; ROSIGLITAZONE;

ARTICLE; CAPILLARY ELECTROPHORESIS; DRUG STRUCTURE; ENANTIOMER; ENZYME ISOLATION; ENZYME STABILITY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; PH; PRIORITY JOURNAL; RACEMIZATION;

ALGORITHMS; CHEMISTRY, PHARMACEUTICAL; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DRUG STABILITY; ELECTROPHORESIS, CAPILLARY; HYDROGEN-ION CONCENTRATION; MOLECULAR STRUCTURE; SOLUTIONS; STEREOISOMERISM; TECHNOLOGY, PHARMACEUTICAL; THIAZOLIDINEDIONES; TIME FACTORS;

EID: 36849086938     PISSN: 07317085     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jpba.2007.09.004     Document Type: Article

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