Intrahepatic cholestasis of pregnancy: Detection with urinary bile acid assays

Journal of Perinatal Medicine

Volumn 35, Issue 6, 2007, Pages 486-491

  Huang, William M ^a,b   Seubert, David E ^a   Donnelly, James G ^a   Liu, Mengling ^a   Javitt, Norman B ^a  

^a NEW YORK UNIVERSITY   (United States)

^b NEW YORK UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

Bile acid; Bile acid sulfate; Cholestasis of pregnancy; Diagnosis; Sensitivity and specificity; Urine

Indexed keywords

BILE ACID; URSODEOXYCHOLIC ACID;

ADULT; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; CREATININE URINE LEVEL; FEMALE; GESTATIONAL AGE; HUMAN; INTERMETHOD COMPARISON; INTRAHEPATIC CHOLESTASIS; NON SULFATED URINE BILE ASSAY; PREGNANCY; PRIORITY JOURNAL; PRURITUS; QUANTITATIVE ASSAY; SENSITIVITY AND SPECIFICITY; URINALYSIS; URINE BILE ACID SULFATE ASSAY;

ADULT; BILE ACIDS AND SALTS; CASE-CONTROL STUDIES; CHOLESTASIS, INTRAHEPATIC; FEMALE; HUMANS; PREGNANCY; PREGNANCY COMPLICATIONS; SENSITIVITY AND SPECIFICITY;

EID: 36849082448     PISSN: 03005577     EISSN: 16193997     Source Type: Journal    
DOI: 10.1515/JPM.2007.128     Document Type: Article

References (26)

1. Abedin P, Weaver JB, Egginton E. Intrahepatic cholestasis of pregnancy: prevalence and ethnic distribution. Ethn Health. 1999;4:35-7.
2. Alsulyman OM, Ouzounian JG, Ames-Castro M, Goodwin TM. Intrahepatic cholestasis of pregnancy: perinatal outcome associated with expectant management. Am J Obstet Gynecol. 1996;175:957-60.
3. Caughey AB. Cholestasis of pregnancy: in need of a more rapid diagnosis. J Perinatol. 2006;26:525-6.
4. Dann AT, Kenyon AP, Seed PT, Poston L, Shennan AH, Tribe RM. Glutathione S-transferase and liver function in intrahepatic cholestasis of pregnancy and pruritus gravidarum. Hepatology. 2004;40:1406-14.
5. Fisk NM, Storey GN. Fetal outcome in obstetric cholestasis. Br J Obstet Gynaecol. 1988;95:1137-43.
6. Glantz A, Marschall HU, Mattsson LA. Intrahepatic cholestasis of pregnancy: relationships between bile acid levels and fetal complication rates. Hepatology. 2004;40:467-74.
7. Kato T, Yoneda M, Nakamura K, Makino I. Enzymatic determination of serum 3 alpha-sulfated bile acids concentration with bile acid 3 alpha-sulfate sulfohydrolase. Dig Dis Sci. 1996;41:1564-70.
8. Kenyon AP, Piercy CN, Girling J, Williamson C, Tribe RM, Shennan AH. Pruritus may precede abnormal liver function tests in pregnant women with obstetric cholestasis: a longitudinal analysis. Br J Obstet Gynaecol. 2001;108:1190-2.
9. Kimura A, Suzuki M, Murai T, Inoue T, Kato H, Hori D, et al. Perinatal bile acid metabolism: analysis of urinary bile acids in pregnant women and newborns. J Lipid Res. 1997;38:1954-62.
10. Laatikainen T, Ikonen E. Fetal prognosis in obstetric hepatosis. Annales Chirurgiae et Gynaecologiae Fenniae. 1975;64:155-64.
11. Laatikainen TJ, Peltonen JI, Nylander PL. Effect of maternal intrahepatic cholestasis on fetal steroid metabolism. J Clin Invest. 1974;53:1709-15.
12. Lammert F, Marschall HU, Glantz A, Matern S. Intrahepatic cholestasis of pregnancy: molecular pathogenesis, diagnosis and management. J Hepatol. 2000;33:1012-21.
13. Lee RH, Goodwin TM, Greenspoon J, Incerpi M. The prevalence of intrahepatic cholestasis of pregnancy in a primarily Latina Los Angeles population. J Perinatol. 2006;26:527-32.
14. Londero F, San Marco L. Intrahepatic cholestasis of pregnancy: are we really able to predict fetal outcome? Am J Obstet Gynecol. 1997;177:1274.
15. Lopez J, Glasinovic JC, Marinovic I, Vela P, Ahumada E, Valdivia MT, et al. Caracterization clinica y de laboratorio en cien casos de colestasia gravidica. Revista Chilena de Obstetricia y Ginecologia. 1982;47:215-21.
16. Marukin Bio Inc. UBASTEC-AUTO - Determination of urinary bile acid sulfates (UBAS). Updated April 30, 2006. Cited Jan 10, 2007. Available from http://marukin-bio.com/english/products/diagnostics/ubas_auto.html.
17. Meng LJ, Reyes H, Palma J, Hernandez I, Ribalta J, Sjovall J. Profiles of bile acids and progesterone metabolites in the urine and serum of women with intrahepatic cholestasis of pregnancy. J Hepatol. 1997;27:346-57.
18. Nakamura K, Yoneda M, Kimura A, Tamori K, Yokohama S, Sato Y, et al. Increase of sulfated ursodeoxycholic acid in the serum and urine of patients with chronic liver disease after ursodeoxycholic acid therapy. J Gastroenterol Hepatol. 1996;11:385-90.
19. Reid R, Ivey KJ, Rencoret RH, Storey B. Fetal complications of obstetric cholestasis. Br Med J. 1976;1:870-2.
20. Rioseco AJ, Ivankovic MB, Manzur A, Hamed F, Kato SR, Parer JT, et al. Intrahepatic cholestasis of pregnancy: a retrospective case-control study of perinatal outcome. Am J Obstet Gynecol. 1994;170:890-5.
21. Roncaglia N, Arreghini A, Locatelli A, Bellini P, Andreotti C, Ghidini A. Obstetric cholestasis: outcome with active management. Eur J Obstet Gynecol Reprod Biol. 2002;100:167-70.
22. Sentilhes L, Verspyck E, Pia P, Marpeau L. Fetal death in a patient with intrahepatic cholestasis of pregnancy. Obstet Gynecol. 2006;107:458-60.
23. Simko V, Michael S, Kelley RE. Predictive value of random sample urine bile acids corrected by creatinine in liver disease. Hepatology. 1987;7:115-21.
24. Thomassen PA. Urinary bile acids during development of recurrent cholestasis of pregnancy. Eur J Clin Invest. 1979;9:417-23.
25. Ushijima K, Kimura A, Inokuchi T, Yamato Y, Maeda K, Yamashita Y, et al. Placental transport of bile acids: analysis of bile acids in maternal serum and urine, umbilical cord blood, and amniotic fluid. Kurume Med J. 2001;48:87-91.
26. Zollner G, Marschall H-U, Wagner M, Trauner M. Role of nuclear receptors in the adaptive response to bile acids and cholestasis: pathogenetic and therapeutic considerations. Molecular Pharmaceutics. 2006;3:231-51.