Subharmonic Contrast Intravascular Ultrasound for Vasa Vasorum Imaging

Ultrasound in Medicine and Biology

Volumn 33, Issue 12, 2007, Pages 1859-1872

  Goertz, David E ^a,b   Frijlink, Martijn E ^a   Tempel, Dennie ^a   Bhagwandas, Vijay ^a,c   Gisolf, Andries ^c   Krams, Robert ^a   de Jong, Nico ^a,b,d   van der Steen, Antonius F W ^a,b  

^a ERASMUS MEDICAL CENTER   (Netherlands)

^b ROYAL NETHERLANDS ACADEMY OF ARTS AND SCIENCES   (Netherlands)

^c DELFT UNIVERSITY OF TECHNOLOGY   (Netherlands)

^d UNIVERSITY OF TWENTE   (Netherlands)

Author keywords

Atherosclerosis; Contrast agents; Coronary artery; Intravascular ultrasound; Microbubbles; Nonlinear; Subharmonic; Vasa vasorum; Vulnerable plaque

Indexed keywords

CATHETERS; HARMONIC GENERATION; NATURAL FREQUENCIES; NEEDLES; NONLINEAR SYSTEMS;

ATHEROSCLEROSIS; CONTRAST AGENTS; CORONARY ARTERY; INTRAVASCULAR ULTRASOUND; VASA VASORUM IMAGING; VULNERABLE PLAQUE;

ULTRASONIC IMAGING;

CONTRAST MEDIUM; PERFLUTREN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; AORTA; ARTICLE; ATHEROSCLEROSIS; CONTRAST ENHANCEMENT; CONTROLLED STUDY; DIAGNOSTIC IMAGING; FREQUENCY ANALYSIS; IMAGE ANALYSIS; IN VIVO STUDY; INTRAVASCULAR ULTRASOUND; NONHUMAN; NONLINEAR SYSTEM; PRIORITY JOURNAL; RABBIT; SIGNAL TRANSDUCTION; VASA VASORUM;

ANIMALS; AORTIC DISEASES; ATHEROSCLEROSIS; CONTRAST MEDIA; FEASIBILITY STUDIES; FLUOROCARBONS; IMAGE INTERPRETATION, COMPUTER-ASSISTED; MICROSPHERES; PHANTOMS, IMAGING; RABBITS; VASA VASORUM;

EID: 36849078758     PISSN: 03015629     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ultrasmedbio.2007.05.023     Document Type: Article

References (67)

1. Bamber J.C. Attenuation and absorption. In: Hill C.R., Bamber J.C., and ter Haar G.R. (Eds). Physical principles of medical ultrasonics. 2nd edition (2004), Wiley, Chichester, UK 188-199
2. Borsboom J.M.G., Chin C.T., and de Jong N. Nonlinear coded excitation method for ultrasound contrast imaging. Ultrasound Med Biol 29 (2003) 277-284
3. Cachard C., Finet G., Bouakaz A., Tabib A., Francon D., and Gimenez G. Ultrasound contrast agents in intravascular echography: An in vitro study. Ultrasound Med Biol 23 (1997) 705-717
4. Carlier S., Kakadiaris A., Dib N., and Nagavi M. Vasa vasorum imaging: A new window to the clinical detection of vulnerable atherosclerotic plaques. Curr Atheroscl Rep 7 (2005) 164-169
5. Cheung K., Couture O., Bevan P.D., Burns P.N., and Foster F.S. The effect of bubble size distribution and driving frequency on the "subharmonic" response from Definity™ microbubbles. Proc IEEE Ultrason Symp (2005) 850-853
6. de Jong N., Bouakaz A., and Ten Cate F.J. Contrast harmonic imaging. Ultrasonics 40 (2002) 567-573
7. de Boer O.J., van der Wal A.C., Teeling P., and Becker A.E. Leucocyte recruitment in rupture prone regions of lipid-rich plaques: A prominent role for neovascularization?. Cardiovasc Res 41 (1999) 443-449
8. de Korte C.L., Cespedes E.I., van der Steen A.F.W., Norder B., and te Nijenhuis K. Elastic and acoustic properties of vessel mimicking material for elasticity imaging. Ultrasonic Imag 19 (1997) 112-126
9. Demos S.M., Alkan-Onyuksel H., Kane B.J., Ramani K., Nagaraj A., Greene R., Klegerman M., and McPherson D.D. In vivo targeting of acoustically reflective liposomes for intravascular and transvascular ultrasonic enhancement. J Am Coll Cardiol 33 (1999) 867-875
10. Edelman E.R., Nugent M.A., Smith L.T., and Karnovsky M.J. Basic fibroblast growth factor enhances the coupling of intimal hyperplasia and proliferation of vasa vasorum in injured rat arteries. J Clin Invest 89 (1992) 465-473
11. Ellegala D.B., Poi H.L., Carpenter J.E., Klibanov A.L., Kaul S., Shaffrey M.E., Sklenar J., and Lindner J.R. Imaging tumor angiogenesis with contrast ultrasound and microbubbles targeted to alpha. (v) beta 3. Circulation 108 (2003) 336-341
12. Feinstein S.B. The powerful microbubble: From bench to bedside, from intravascular indicator to therapeutic delivery system, and beyond. Am J Physiol 287 (2004) H450-H457
13. Forsberg F., Shi W.T., and Goldberg B.B. Subharmonic imaging of contrast agents. Ultrasonics 38 (2000) 93-98
14. Forsberg F., Shi W.T., and Jadidian B. Multi-frequency harmonic arrays: Initial experience with a novel transducer concept for nonlinear contrast imaging. Ultrasonics 43 (2004) 79-85
15. Frijlink M.E., Goertz D.E., van Damme L.C., Krams R., and van der Steen A.F. Intravascular ultrasound tissue harmonic imaging in vivo. IEEE Trans Ultrason Ferroelectr Freq Contr 53 (2006) 1844-1852
16. Frijlink M.E., Goertz D.E., Vos H.J., Tesselaar E., Blacquière G., Gisolf A., Krams R., and van der Steen A.F.W. Harmonic intravascular ultrasound imaging with a dual-frequency catheter. Ultrasound Med Biol 32 (2006) 1649-1654
17. Frijlink M.E., Goertz D.E., de Jong N., and van der Steen A.F.W. Pulse-inversion sequences for mechanically scanned transducers. IEEE Ultrason Symp (2006) 1286-1289
18. Glaser R., Selzer F., Faxon D.P., Laskey W.K., Cohen H.A., Slater J., Detre K.M., and Wilensky R.L. Clinical progression of incidental, asymptomatic lesions discovered during culprit vessel coronary intervention. Circulation 111 (2005) 143-149
19. Goertz D.E. High frequency flow imaging of the microcirculation. PhD thesis (2002), University of Toronto
20. Goertz D.E., Yu J.L., Kerbel R.S., Burns P.N., and Foster F.S. High frequency 3D imaging of the microcirculation. Ultrasound Med Biol 29 (2003) 39-51
21. Goertz D.E., Cherin E., Needles A., Karshafian R., Duckett A., Burns P.N., and Foster F.S. High frequency nonlinear b-scan imaging of microbubble contrast agents. IEEE Trans Ultrason Ferroelectr Freq Control 52 (2005) 65-79
22. Goertz D.E., van Wamel A., Frijlink M.E., de Jong N., and van der Steen A.F.W. Nonlinear imaging of targeted microbubbles with intravascular ultrasound. IEEE Ultrason Symp (2005) 2003-2006
23. Goertz D.E., Frijlink M.E., de Jong N., and van der Steen A.F. Nonlinear intravascular ultrasound contrast imaging. Ultrasound Med Biol 32 (2006) 491-502
24. Goertz D.E., Frijlink M.E., Tempel D., van Damme L.C., Krams R., Schaar J.A., Ten Cate F.J., Serruys P.W., de Jong N., and van der Steen A.F.W. Contrast harmonic intravascular ultrasound: A feasibility study for vasa vasorum imaging. Invest Radiol 41 (2006) 631-638
25. Goertz D.E., Frijlink M.E., de Jong N., and van der Steen A.F.W. High frequency attenuation properties of Definity™ and modified Definity™ populations. IEEE Ultrason Symp (2006) (in press)
26. Goertz D.E., Frijlink M.E., de Jong N., and van der Steen A.F.W. High frequency nonlinear scattering from a micrometer to submicrometer sized lipid encapsulated contrast agent. Ultrasound Med Biol 32 (2006) 569-577
27. Hamilton A.J., Huang S.L., Warnick D., Rabbat M., Kane B., Nagaraj A., Klegerman M., and McPherson D.D. Intravascular ultrasound molecular imaging of atheroma components in vivo. J Am Coll Cardiol 43 (2004) 453-460
28. Herrmann J., Lerman L.O., Rodriguez-Porcel M., Holmes D.R., Richardson D.M., Ritman E.L., and Lerman A. Coronary vasa vasorum neovascularization precedes epicardial endothelial dysfunction in experimental hypercholesterolemia. Cardiovasc Res 51 (2001) 762-766
29. Hope-Simpson D., Chin C.T., and Burns P.N. Pulse inversion Doppler: A new method for detecting non-linear echoes from microbubble contrast agents. IEEE Trans Ultrason Ferroelectr Freq Control 46 (1999) 372-382
30. Kakadiaris I., O'Malley S., Vavuranakis M., Carlier S., Hartley C., Metcalfe R., Mehran R., and Naghavi M. Intravascular ultrasound-based imaging of vasa vasorum for the detection of vulnerable atherosclerotic plaque. J Am Coll Cardiol 47 (2006) 264A
31. Kerwin W., Hooker A., Spilker M., Vicini P., Ferguson M., Hatsukami T., and Yuan C. Quantitative magnetic resonance imaging analysis of neovasculature volume in carotid atherosclerotic plaque. Circulation 107 (2003) 851-856
32. Kolodgie F.D., Gold H.K., Burke A.P., Fowler D.R., Kruth H.S., Weber D.K., Farb A., Guerrero L.J., Hayase M., Kutys R., Narula J., Finn A.V., and Virmani R. Intraplaque hemorrhage and progression of coronary atheroma. N Engl J Med 349 (2002) 2316-2325
33. Kruse D.E., and Ferrara K.W. A new high resolution color flow system using an eigendecomposition based adaptive filter for clutter rejection. IEEE Trans Ultrason Ferroelectr Freq Control 49 (2002) 1384-1399
34. Kumamoto M., Nakashima Y., and Sueshi K. Intimal neovascularization in human coronary atherosclerosis-its origin and pathophysiological significance. Human Pathol 26 (1995) 450-456
35. Kwon H.M., Sangiorgi G., Ritman E.L., McKenna C., Holmes D.R., Schwartz R.S., and Lerman. A Enhanced coronary vasa vasorum neovascularization in experimental hypercholesterolemia. J Clin Invest 101 (1998) 1551-1556
36. Lockwood G.R., Ryan L.K., Hunt J.W., and Foster F.S. Measurement of the ultrasonic properties of vascular tissues and blood from 35-65 MHz. Ultrasound Med Biol 17 (1991) 653-666
37. Milei J., Parodi J.C., Alonso G.F., et al. Carotid rupture and intraplaque hemorrhage: Immunophenotype and role of cells involved. Am Heart J 136 (1998) 1096-1105
38. Moreno P.R., Purushothaman R., Fuster V., Echeverri D., Truszczynska H., Sharma S.K., Badimon J.J., and O'Connor W.N. Plaque neovascularization is increased in ruptured atherosclerotic lesions of human aorta-Implications for plaque vulnerability. Circulation 110 (2004) 2032-2038
39. Morgan K., Averkiou M., and Ferrara K. The effect of the phase of transmission on contrast agent echoes. IEEE Trans Ultrason Ferroelectr Freq Control 45 (1998) 872-875
40. Moulton K.S., Vakili K., Zurakowski D., Soliman M., Butterfield C., Sylvin E., Lo K.M., Gillies S., Javaherian K., and Folkman J. Inhibition of plaque neovascularization reduces macrophage accumulation and progression of advanced atherosclerosis. Proc Nat Acad Sci 100 (2003) 4736-4741
41. Moulton K.S. Angiogenesis in atherosclerosis: Gathering evidence beyond speculation. Curr Opinions Lipid 17 (2006) 548-555
42. Nair A., Kuban B.D., Tuzcu E.M., Schoenhagen P., Nissen S.E., and Vince D.G. Coronary plaque classification with intravascular ultrasound radiofrequency data analysis. Circulation 106 (2002) 2200-2206
43. Needles A., Goertz D.E., Karshafian R., Cherin E., Brown A.S., Burns P.N., and Foster F.S. High frequency subharmonic flow imaging of contrast agents. IEEE Ultrason Symp (2005) 629-631
44. Nissen S.E., and Yock P. Intravascular ultrasound-Novel pathophysiological insights and current clinical applications. Circulation 103 (2001) 604-616
45. Nicholls S.J., Sipahi I., Schoenhagen P., Crowe T., Tuzcu E.M., and Nissen S.E. Application of intravascular ultrasound in anti-atherosclerotic drug development. Nat Rev Drug Discov 5 (2006) 485-492
46. O'Malley S.M., Vavuranakis M., Naghavi M., and Kakadiaris I.A. Intravascular ultrasound-based imaging of vasa vasorum for the detection of vulnerable atherosclerotic plaque. Lecture Notes Comp Sci 3749 (2005) 343-351
47. Prosperetti A. Application of the subharmonic threshold to the measurement of the damping of oscillating gas bubbles. J Acoust Soc Am 61 (1977) 11-17
48. Sarkar K., Shi W.T., Chatterjee D., and Forsberg F. Characterization of ultrasound contrast microbubbles using in vitro experiments and viscous and viscoelastic interface models for encapsulation. J Acoustical Society of America 118 1 (2005) 539-550
49. Schaar J.A., de Korte C.L., Mastik F., Strijder C., Pasterkamp G., Boersma E., Serruys P.W., and van der Steen A.F.W. Characterizing vulnerable plaque features with intravascular elastography. Circulation 108 (2003) 2636-2641
50. Schaar J.A., Muller J.E., Falk E., Virmani R., Fuster V., Serruys P.W., Colombo A., Stefanadis C., Cassells S.W., Moreno P.R., Maseri A., and van der Steen A.F.W. Terminology for high-risk and vulnerable coronary artery plaques-Report of a meeting on the vulnerable plaque, June 17 and 18, 2003, Santorini, Greece. Eur Heart J 25 (2004) 1077-1082
51. Schaar J.A., de Korte C.L., Mastik F., van Damme L.C.A., Krams R., Serruys P.W., and van der Steen A.F.W. Three-dimensional palpography of human coronary arteries-Ex vivo validation and in-patient evaluation. Herz 30 (2005) 125-133
52. Schmidt-Nielsen K. Scaling: Why is animal size so important (1984), Cambridge University Press, Cambridge
53. Schoenhagen P., Ziada K.M., Vince D.G., Nissen S.E., and Tuzcu E.M. Relation of matrix-metalloproteinase 3 found in coronary lesion samples retrieved by directional coronary atherectomy to intravascular ultrasound observations on coronary remodeling. J Am Coll Cardiol 38 (2001) 297-306
54. Shankar P.M., Krishna P.D., and Newhouse V.L. Advantages of subharmonic over second harmonic backscatter for contrast-to-tissue enhancement. Ultrasound Med Biol 24 (1998) 395-399
55. Shen C.C., and Li P.C. Motion artifacts of pulse inversion-based tissue harmonic imaging. IEEE Trans Ultrason Ferroelectr Freq Control 49 (2002) 1203-1211
56. Shen C.C., and Li P.C. Pulse-inversion-based fundamental imaging for contrast detection. IEEE Trans Ultrason Ferroelectr Freq Control 50 (2003) 1124-1133
57. Shi W.T., and Forsberg F. Ultrasonic characterization of the nonlinear properties of contrast microbubbles. Ultrasound Med Biol 26 (2000) 93-104
58. Szabo T.L. Diagnostic imaging from the inside out (2004), Elsevier Academic Press, Burlington, MA
59. Takeuchi S., Zaabi M.R.A.A., and Sato T. Ultrasound transducer with double-peak frequency characteristics for subharmonic imaging. Jpn J Appl Phys 42 Pt 1 (2003) 3253-3254
60. Virmani R., Kolodgie F.D., Burke A.P., Farb A., and Schwartz S.M. Lessons from sudden coronary death-A comprehensive morphological classification scheme for atherosclerotic lesions. Arteriol Thromb Vasc Biol 20 (2000) 1262-1275
61. Virmani R., Burke A.P., Farb A., and Kolodgie F.D. Pathology of the vulnerable plaque. J Am Coll Cardiol 47 (2006) C13-C18
62. Vos H.J., Frijlink M.E., Droog E., Goertz D.E., Blacquière Gisolf G.A., de Jong N., and van der Steen A.F.W. A 20-40 MHz ultrasound transducer for intravascular harmonic imaging. IEEE Trans Ultrason Ferroelectr Freq Control 52 (2005) 2418-2422
63. Waxman S., Ishibashi F., and Muller J.E. Detection and treatment of vulnerable plaques and vulnerable patients: novel approaches to prevention of coronary events. Circulation 114 (2006) 2390-2411
64. Williams J.K., and Heistad D.D. Structure and function of vasa vasorum. Trends Cardiovasc Med 6 (1996) 53-57
65. Williams R., Needles A., Cherin E., Burns P.N., Foster F.S., Leavens C., and Sherar M.D. Harmonic chirp imaging with ultrasound contrast agents at high frequency. IEEE Ultrason Symp (2006) 228-231
66. Winter P.M., Morawski A.M., Caruthers S.D., Fuhrhop R.W., Zhang H.Y., Williams T.A., Allen J.S., Lacy E.K., Robertson J.D., Lanza G.M., and Wickline S.A. Molecular imaging of angiogenesis in early-stage atherosclerosis with alpha. (v) beta(3)-integrin-targeted nanoparticles. Circulation 108 (2003) 2270-2274
67. Zhang Y., Cliff W.J., Schoefl G.I., and Higgins G. Immunohistochemical study of intimal microvessels in coronary atherosclerosis. Am J Pathol 143 (1993) 164-173