The Nature of Skin Pigmentations in Chronic Venous Insufficiency: A Preliminary Report

European Journal of Vascular and Endovascular Surgery

Volumn 35, Issue 1, 2008, Pages 111-118

  Caggiati, A ^a   Rosi, C ^a   Franceschini, M ^a   Innocenzi, D ^a  

^a SAPIENZA UNIVERSITY OF ROME   (Italy)

Author keywords

Chronic venous insufficiency; Hemosiderin; Melanin; Stasis dermatitis; Varicose veins

Indexed keywords

HEMOSIDERIN;

ADULT; ARTICLE; CHRONIC VEIN INSUFFICIENCY; CLINICAL ARTICLE; CONTROLLED STUDY; DISEASE SEVERITY; ERYTHROCYTE DISORDER; FEMALE; HISTOPATHOLOGY; HUMAN; LIPODERMATOSCLEROSIS; MALE; PATHOGENESIS; PRIORITY JOURNAL; SKIN BIOPSY; SKIN PIGMENTATION; TISSUE SECTION; VARICOSIS; VASCULAR SURGERY;

CASE-CONTROL STUDIES; CHRONIC DISEASE; ERYTHROCYTES; FEMALE; HEMOSIDERIN; HUMANS; MALE; MELANINS; MIDDLE AGED; PILOT PROJECTS; SKIN; SKIN PIGMENTATION; VARICOSE VEINS; VENOUS INSUFFICIENCY;

EID: 36849067428     PISSN: 10785884     EISSN: 15322165     Source Type: Journal    
DOI: 10.1016/j.ejvs.2007.08.007     Document Type: Article

References (28)

1. Porter J.M., and Moneta G.L. Reporting standards in venous disease: an update. International Consensus Committee on Chronic Venous Disease. J Vasc Surg 21 (1995) 635-645
2. Allegra C., Antignani P.L., Bergan J.J., Carpentier P.H., Coleridge Smith P., Cornu-Thenard A., et al. The "C" of CEAP: suggested definitions and refinements: an International Union of Phlebology conference of experts. J Vasc Surg 37 (2003) 129-131
3. Kim D., and Kang W.H. Role of Dermal Melanocytes in Cutaneous Pigmentation of Stasis Dermatitis. J Korean Med Sci 17 (2002) 648-654
4. Rivera M.R., Ishihara M., and Mihara M. A case of non selective phagocytosis of hemosiderin and melanin of dermal hystiocytes in stasis dermatitis. Arch Dermatol Res 295 (2003) 19-23
5. Eklof B., Bergan J.J., Gloviczki P., Kistner R.L., Meissner M.H., Smith P.C., et al. American Venous Forum International Ad Hoc Committee for Revision of the CEAP ClassificationRevision of the CEAP classification for chronic venous disorders: consensus statement. J Vasc Surg 40 (2004) 1248-1252
6. Eberhardt R.T., and Raffetto J.D. Chronic venous insufficiency. Circulation 111 (2005) 2398-2409
7. Farmer E.R., and Hood A.F. Pathology of the skin. 2nd ed. (2000), McGraw-Hill, Health Professions Division, New York pp. 795
8. Fitzpatrick T.B. The validity and practicality of sun-reactive skin types I through VI. Arch Dermatol 124 (1988) 869-871
9. Rutherford R.B., Padberg Jr. F.T., Comerota A.J., Kistner R.L., Meissner M.H., and Moneta G.L. Venous severity scoring: an adjunct to venous outcome assessment. J Vasc Surg 31 (2000) 1307-1312
10. Coleridge Smith P., Labropoulos N., Partsh H., Myers K., Nicolaides A., and Cavezzi A. Duplex ultrasound investigation of the veins in chronic venous disease of the lower limbs-UIP consensus document. Part I. Basic principles. Eur J Vasc Endovasc Surg 31 (2006) 83-92
11. Kanitakis J., Souillet A.L., Butnaru C., and Claudy A. Melanocyte stimulation in focal dermal hypoplasia with unusual pigmented skin lesions: a histologic and immunohistochemical study. Pediatr Dermatol 20 (2003) 249-253
12. Pearse A.G.E. Histochemistry. Theoretical and applied. 3rd ed. vol. 2 (1972), Churchill Livingstone, Edinburgh London pp. 1130
13. Unver M., Freyschmidt-Paul P., Horster S., Wenck H., Blatt T., and Elsasser H.P. Alterations in the epidermal-dermal melanin axis and factor XIIIa melanophages in seile lentigo and ageing skin. Dermopathology 155 (2006) 119-128
14. Carpentier P.H., Cornu-Thenard A., Uhl J.F., Partsch H., and Antignani P.L. Appraisal of the information content of the C classes of CEAP clinical classification of chronic venous disorders: a multicenter evaluation of 872 patients. J Vasc Surg 37 (2003) 827-833
15. Nagao S., Ito M., Suzuki M., Satoh N., and Iijima S. Electron microscopic study of histological pigmentary incontinence-methods of melanosome translocation from the epidermis to the dermis. Fukushima J Med Sci 32 (1986) 141-153
16. Chatard H., and Dufour H. Note sur la nature mixte, hematique et melanique, des pigmentations en phlebologie. Phlebologie 36 (1983) 303-306
17. Borovansky J., and Elleder M. Melanosome degradation: fact or fiction. Pigment Cell Res 16 (2003) 280-286
18. Grimes P.E., Yamada N., and Bhawan J. Light microscopic, himmunohistochemical and ultrastrctural alteraztions in patients with melasma. Am J Dermatopathol 27 (2005) 96-101
19. Shibata T., Prota G., and Mishima Y. Non-melanosomal regulatory factors in melanogenesis. J Invest Dermatol 100 (1993) S274-S280
20. Morelli J.G., and Norris D.A. Influence of inflammatory mediators and cytokines on human melanocyte function. J Invest Dermatol 100 Suppl. 2 (1993) 1915-1955
21. Wilkinson L.S., Bunker C., Edwards J.C.W., Scurr J.H., and Coleridge Smith P.D. Leukocytes: their role on the etiopathogenesis of skin damage in venous disease. J Vasc Surg 17 (1993) 669-675
22. Howlader M.H., and Coleridge Smith P.D. Microangiopathy in chronic venous insufficiency: quantitative assessment by capillary microscopy. Eur J Vasc Endovasc Surg 26 (2003) 325-331
23. Virgini-Megalhaes C.E., Porto C.L., Fernandes F.F.A., Dorigo D.M., Bottino D.A., and Bouskela E. Use of microcirculatory parameters to evacuate chronic venous insufficiency. J Vasc Surg 43 (2006) 1037-1044
24. Ruiz Maldonado R., and Orozco-Covarrubias M.L. Postinflammatory hypopigmentation and hyperpigmentation. Semin Cutan Med Surg 16 (1997) 36-43
25. Zamboni P., Tognazzo S., Izzo M., Pancaldi F., Scapoli G.L., Liboni A., et al. Hemochromatosis C282Y gene mutation increases the risk of venous leg ulceration. J Vasc Surg 42 (2005) 309-314
26. Zamboni P., Izzo M., Tognazzo S., carandina S., De Palma M., Catozzi L., et al. The overlapping of local iron overload and HFE mutation in venous leg ulcer pathogenesis. Free Radic Biol Med 40 (2006) 1869-1873
27. Wenner A., Leu H.J., Spycher M., and Brunner U. Ultrastructural changes of capillaries in chronic venous insufficiency. Exp Cell Biol 48 (1980) 1-14
28. Pappas P.J., DeFouw D.O., Venezio L.M., Gorti R., Padberg Jr. F.T., Silva M.B., et al. Morphometric assessment of the dermal microcirculation in patients with chronic venous insufficiency. J Vasc Surg 26 (1997) 784-795