Two outbreaks of Burkholderia cepacia nosocomial infection in a neonatal intensive care unit

Journal of Paediatrics and Child Health

Volumn 44, Issue 1-2, 2008, Pages 62-66

  Lee, Jimmy K F ^a  

^a Hospital Kuala Terengganu   (Malaysia)

Author keywords

Burkholderia cepacia; Neonatal intensive care unit; Nosocomial infection

Indexed keywords

ARTICLE; BACTERIUM ISOLATION; BIRTH WEIGHT; BURKHOLDERIA CEPACIA; CASE CONTROL STUDY; CLINICAL ARTICLE; DELIVERY ROOM; EPIDEMIC; GESTATIONAL AGE; HOSPITAL INFECTION; HUMAN; HUMIDIFIER; INFANT; INFECTION CONTROL; INFECTION RISK; MEDICAL RECORD REVIEW; MORTALITY; MULTIVARIATE LOGISTIC REGRESSION ANALYSIS; NEWBORN; NEWBORN INTENSIVE CARE; PRIORITY JOURNAL; RETROSPECTIVE STUDY; RISK FACTOR; SEPTICEMIA; VENTILATOR;

BURKHOLDERIA CEPACIA; BURKHOLDERIA INFECTIONS; CASE-CONTROL STUDIES; CROSS INFECTION; DISEASE OUTBREAKS; FEMALE; HUMANS; INFANT; INFANT, NEWBORN; INTENSIVE CARE UNITS, NEONATAL; LOGISTIC MODELS; MALAYSIA; MALE; RETROSPECTIVE STUDIES; RISK FACTORS; SEPSIS; VENTILATORS, MECHANICAL;

EID: 36849058632     PISSN: 10344810     EISSN: 14401754     Source Type: Journal    
DOI: 10.1111/j.1440-1754.2007.01173.x     Document Type: Article

References (20)

1. Gilligan PH, Lum G, Vandamme PAR, Whittier S. Burkholderia, Stenotrophomonas, Ralstonia, Brevundimonas, Comamonas, Delftia, Pandoraea, and Acidovorax. In : Murray PR, Baron EJ, Jorgensen JH, Pfaller MA, Yolken RH, eds. Manual of Clinical Microbiology, Chapter 48, 8th edn. Wasington D.C. : American Society of Microbiology, 2003 729 48.
2. Rutala WA, Weber DJ. Water as a reservoir of nosocomial pathogens. Infect. Control. Hosp. Epidemiol. 1997 18 : 609 16.
3. Siegel JD, Duer PN, Haley CE, Thomassen KA, Perotta DM. Contaminated povidone-iodine solution - Texas. MMWR 1989 38 : 133 4.
4. Brady MT. Pseudomonas and related genera. In : Feigin RD, Cherry JD, Demmler GJ, Kaplan SL, eds. Textbook of Pediatric Infectious Diseases, Chapter 129, 5th edn. Philadelphia, PA : Saunders, 2004 1557 73.
5. Mangram A, Jarvis WR. Nosocomial Burkholderia cepacia outbreaks and pseudo-outbreaks. Infect. Control. Hosp. Epidemiol. 1996 17 : 718 20.
6. Gravel-Tropper D, Sample ML, Oxley C, Toye B, Woods DE, Garber GE. Three-year outbreak of pseudobacteraemia with Burkholderia cepacia traced to a contaminated blood gas analyzer. Infect. Control. Hosp. Epidemiol. 1996 17 : 737 40.
7. Berkelman RL, Lewin S, Allen JR. Pseudobacteraemia attributed to contamination of povidone-iodine with Pseudomonas cepacia. Ann. Intern. Med. 1981 95 : 32 6.
8. Conly JM, Klass L, Larson L, Kennedy J, Low DE, Harding GKM. Pseudomonas cepacia colonization and infection in intensive care units. Can. Med. Assoc. J. 1986 134 : 363 6.
9. Weems JJ. Nosocomial outbreak of Pseudomonas cepacia associated with contamination of reusable electronic ventilator temperature probes. Infect. Control. Hosp. Epidemiol. 1993 14 : 583 6.
10. Hamill RJ, Houston ED, Georghiou PR et al. An outbreak of Burkholderia cepacia respiratory tract colonization and infection associated with nebulised albuterol therapy. Ann. Intern. Med. 1995 122 : 762 6.
11. Matrician L, Ange G, Burns S et al. Nosocomial Burkholderia cepacia infection and colonization associated with intrinsically contaminated mouthwash. MMWR 1998 47 : 926 8.
12. Panlilio AL, Becj-Sague CM, Siegel JD et al. Infections and pseudo-infections due to povidone-iodine solution contaminated with Pseudomonas cepacia. Clin. Infect. Dis. 1992 14 : 1078 83.
13. Rapkin RH. Pseudomonas cepacia in an intensive care nursery. Pediatrics 1976 57 : 239 43.
14. Kohyaoglu O, Nola B, Kumar A. Burkholderia cepacia sepsis in neonates. Pediatr. Infect. Dis. J. 1995 14 : 815 16.
15. Moreira BM, Leobons MBGP, Pellegrino FLPC et al. Ralstonia picketti and Burkholderia cepacia complex bloodstream infection related to infusion of contaminated water for injection. J. Hosp. Infect. 2005 60 : 51 5.
16. Klein JO. Bacterial Sepsis and Meningitis. In : Remington JS, Klein JO, eds. Infectious Diseases of the Fetus and Newborn Infant, Chapter 21, 5th edn. Philadelphia, PA : W.B. Saunders, 2001 943 98.
17. Akerman P, Brahman M, Brown SM et al. Outbreak Investigation, Basic Infection Control Manual, American International Health Alliance, 2nd Edition 2003; Chapter 3b: 41-50. Available from URL: http://www.eurasiahealth.org/eng/ resources/81458 [accessed 6 July 2007].
18. Center of Disease Control CDC. Steps of an outbreak investigation. Available from: http://www.cdc.gov/excite/classroom/outbreak/steps.htm [accessed 3 June 2006].
19. Doit C, Lonkil C, Simon AM et al. Outbreak of Burkholderia cepacia bacteraemia in a Pediatric Hospital due to contamination of lipid emulsion stoppers. J. Clin. Microbiol. 2004 5 : 2227 30.
20. Speert DP, Deborah H, Vandamme P, Corey M, Mahenthiralingam E. Epidemiology of Burkholderia cepacia complex in patients with cystic fibrosis, Canada. Emerg. Infect. Dis. 2002 8 : 181 7.