Venous thromboembolism in Wegener's granulomatosis

Journal of Rheumatology

Volumn 34, Issue 12, 2007, Pages 2323-2325

  Lamprecht, Peter ^a,c   Holl Ulrich, Konstanze ^a   Wieczorek, Stefan ^b  

^a UNIVERSITY OF LÜBECK   (Germany)

^b RUHR UNIVERSITY BOCHUM   (Germany)

^c NONE   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CARDIOLIPIN ANTIBODY; MYELOBLASTIN; NEUTROPHIL CYTOPLASMIC ANTIBODY;

ANTIGEN PRESENTATION; CELL DAMAGE; CELL MATURATION; CRYSTAL; CYTOKINE RELEASE; CYTOMEGALOVIRUS INFECTION; DENDRITIC CELL; DISEASE PREDISPOSITION; EDITORIAL; ENDOTHELIUM; GENE MUTATION; GENETIC RISK; GENETIC VARIABILITY; HUMAN; HYPERCOAGULABILITY; IMMUNE RESPONSE; MONOSODIUM URATE CRYSTAL; MORPHOLOGY; NEUTROPHIL; PHLEBITIS; PRIORITY JOURNAL; T LYMPHOCYTE ACTIVATION; TH1 CELL; VASCULITIS; VENOUS THROMBOEMBOLISM; WEGENER GRANULOMATOSIS;

EID: 36849056708     PISSN: 0315162X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Editorial

References (20)

1. Bacon PA. The spectrum of Wegener's granulomatosis and disease relapse. N Engl J Med 2005;352:330-2.
2. Heeringa P, Huugen D, Cohen Tervaert JW. Antineutrophil cytoplasmic autoantibodies and leukocyte-endothelial interactions: a sticky connection? Trends Immunol 2005;26:561-4.
3. Pfister H, Ollert M, Fröhlich LF, et al. Antineutrophil cytoplasmic autoantibodies (ANCA) against the murine homolog of proteinase 3 (Wegener's autoantigen) are pathogenic in vivo. Blood 2004;104:1411-8.
4. Shi Y, Evans JE, Rock KL. Molecular identification of a danger signal that alerts the immune system to dying cells. Nature 2003;425:516-25.
5. Matzinger P. Friendly and dangerous signals: Is the tissue in control? Nat Immunol 2007;8:11-3.
6. Csernok E, Ai M, Gross WL, et al. Wegener's autoantigen induces maturation of dendritic cells and licences them for Th1 priming via the protease-activated receptor-2 pathway. Blood 2006;107:4440-8.
7. Zinkernagel RM. Antiinfection immunity and autoimmunity. Ann NY Acad Sci 2002;958:3-6.
8. Lamprecht P, Gross WL, Kabelitz D. T cell alterations and lymphoid neogenesis favoring autoimmunity in Wegener's granulomatosis. Arthritis Rheum 2007;56:1725-7.
9. Wolf G, Porth J, Stahl RA. Thrombosis associated with cytomegalovirus infection in patients with ANCA-positive vasculitis. Am J Kidney Dis 2001;38:E27.
10. Von Scheven E, Lu TT, Emery HM, Elder ME, Wara DW. Thrombosis and pediatric Wegener's granulomatosis: Acquired and genetic risk factors for hypercoagulability. Arthritis Rheum 2003;49:862-5.
11. Weidner S, Hafezi-Rachti S, Rupprecht HD. Thromboembolic events as a complication of antineutrophil cytoplasmic antibody-associated vasculitis. Arthritis Rheum 2006;55:146-9.
12. Merkel P, Lo GH, Holbrook JT, et al. High incidence of venous thrombotic events among patients with Wegener's granulomatosis: The Wegener's clinical occurrence of thrombosis (WeCLOT) study. Ann Intern Med 2005;142:620-6.
13. Sebastian JK, Voetsch B, Stone JH, et al. The frequency of anticardiolipin antibodies and genetic mutations associated with hypercoagulability among patients with Wegener's granulomatosis with and without a history of a thrombotic event. J Rheumatol 2007;34:2446-50.
14. Seligsohn U, Lubetsky A. Genetic susceptibility to venous thrombosis. New Engl J Med 2001;344:1222-31.
15. Jagiello P, Gross WL, Epplen J. Complex genetics of Wegener's granulomatosis. Autoimmun Rev 2005;4:42-7.
16. de Bandt M, Ollivier V, Meyer O, et al. Induction of interleukin-1 and subsequent tissue factor expression by anti-proteinase 3 antibodies in human umbilical vein endothelial cells. Arthritis Rheum 1997;40:2030-8.
17. Haubitz M, Gerlach M, Kruse HJ, Brunkhorst R. Endothelial tissue factor stimulation by proteinase 3 and elastase. Clin Exp Immunol 2001;126:584-8.
18. Pendergraft WF III, Preston GA, Shah RR, et al. Autoimmunity is triggered by cPR-3(105-201), a protein complementary to human autoantigen proteinase-3. Nature Med 2004;10:72-9.
19. Bautz DJ, Lionaki S, Yang J, et al. Utilization of a peptide coded by the anti-sense RNA of the PRTN3 gene led to the discovery of anti-plasminogen autoantibodies in PR3-ANCA [abstract]. Clin Exp Rheumatol 2007;25 Suppl 44:S81.
20. Chirinos JA, Tamariz LJ, Lopez G, et al. Large vessel involvement in ANCA-associated vasculitides: report of a case and review of the literature. Clin Rheumatol 2004;23:152-9.