The significance of cerebral toxocariasis

Toxocara: The Enigmatic Parasite

Volumn , Issue , 2006, Pages 58-73

  Holland, Celia V ^a   Hamilton, Clare ^a  

^a TRINITY COLLEGE DUBLIN   (Ireland)

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EID: 36849050018     PISSN: None     EISSN: None     Source Type: Book    
DOI: None     Document Type: Chapter

References (82)

1. Akao, N., Takayanagi, T.H., Suzuki, R., Tsukidate, S. and Fujita, K. (2000) Ocular larva migrans caused by Toxocara cati in Mongolian gerbils and a comparison of ophthalmologic findings with those produced by T. canis. Journal of Parasitology 86, 1133-1135.
2. Akao, N., Tomoda, M., Hayashi, E., Suzuki, R., Shimizu-Suganuma, M., Shichinohe, K. and Fujita, K. (2003) Cerebellar ataxia due to Toxocara infection in Mongolian gerbils, Meriones unguiculatus. Veterinary Parasitology 113, 229-237.
3. Alba-Hurtado, F., Tortora, P.J.L., Tsutsumi, V. and Ortega-Pierres, M.G. (2000) Histopathological investigation of experimental ocular toxocariasis in gerbils. International Journal for Parasitology 30, 143-147.
4. Bardon, R., Cuellar, C. and Guillen, J.L. (1994) Larval distribution of Toxocara canis in BALB/c mice at nine weeks and one year post-inoculation. Journal of Helminthology 68, 359-360.
5. Beautyman, W., Beaver, P.C., Buckley, J.J.C. and Woolf, A.L. (1966) Review of a case previously reported as showing an ascarid larva in the brain. Journal of Pathology and Bacteriology 91, 271-273.
6. Beaver, P.C., Snyder, C.H., Carrera, G.M., Dent, J.H. and Lafferty, J.W. (1952) Chronic eosinophilia due to visceral larva migrans. Pediatrics 9, 7-19.
7. Boes, J. and Helwigh, A.B. (2000) Animal models of intestinal nematode infections of humans. Parasitology 121, 597-5111.
8. Brown, H., Turner, G., Rogerson, S., Tembo, M., Mwenechanya, J., Molyneux, M. and Taylor, T. (1999) Cytokine expression in the brain in human cerebral malaria. Journal of Infectious Diseases 180, 1742-1746.
9. Buijs, J., Lokhorst, W.H., Robinson, J. and Nijkamp, F.P. (1994) Toxocara canis-induced murine pulmonary inflammation analysis of cells and proteins in lung tissue and bronchoalveolar lavage fluid. Parasite Immunology 16, 1-9.
10. Burren, C.H. (1971) The distribution of Toxocara canis larvae in the central nervous system of the mouse. Transactions of the Royal Society of Tropical Medicine and Hygiene 65, 450-453.
11. Burren, C.H. (1972) The distribution of Toxocara canis in the central nervous system of rodents. Transactions of the Royal Society of Tropical and Medicine 66, 937-942.
12. Bush, A.O., Fernandez, J.C., Seed, J. and Esch, G.W. (2001) Parasitism: the Diversity and Ecology of Animal Parasites. Cambridge University Press, Cambridge, Massachusetts.
13. Church, E.M., Wyand, D.S. and Lein, D.H. (1975) Experimentally induced cerebrospinal nematodiasis in rabbits (Oryctolagus cuniculus). American Journal of Veterinary Research 36, 331-335.
14. Cox, D.M. and Holland, C.V. (1998) The relationship between numbers of larvae recovered from the brain of Toxocara canis infected mice and social behaviour and anxiety in the host. Parasitology 116, 579-594.
15. Cox, D.M. and Holland, C.V. (2001a) Influence of mouse strain, infective dose and larval burden in the brain on activity in Toxocara-infected mice. Journal of Helminthology 75, 23-32.
16. Cox, D.M. and Holland, C.V. (2001b) Relationship between three intensity levels of Toxocara canis larvae in the brain and effects on exploration, anxiety, learning and memory in the murine host. Journal of Helminthology 75, 33-41.
17. de Kossodo, S. and Grau, G.E. (1993) Profiles of cytokine production in relation with susceptibility to cerebral malaria. Journal of Immunology 151, 4811-4820.
18. Del Prete, G.F., De Carli, M., Mastromauro, C., Biagiotti, R., Macchia, D., Falagiani, P., Ricci, M. and Romagnani, S. (1991) Purified protein derivative of Mycobacterium tuberculosis and excretory- secretory antigen(s) of Toxocara canis expand in vitro human Tcells with stable and opposite (type 1 T helper or type 2 T helper) profile of cytokine production. Journal of Clinical Investigation 88, 346-50.
19. Dent, J.H., Nichols, R.L., Beaver, P.C., Carrera, G.M. and Staggers, R.J. (1956) Visceral larva migrans; with a case report. American Journal of Pathology 32, 777-803.
20. Dolinksy, Z.S., Burright, R.G. and Donovick, P.J. (1981) Behavioural effects of lead and Toxocara canis in mice. Science 213, 1142-1144.
21. Dolinsky, Z.S., Hardy, C.A., Burright, R.G. and Donovick, P.J. (1985) The progression of behavioural and pathological effects of the parasite Toxocara canis in the mouse. Physiology and Behaviour, 35, 33-42.
22. Done, J.T., Richardson, M.D. and Gibson, T.E. (1960) Experimental visceral larva migrans in the pig. Research Veterinary Science 1, 133-151.
23. Dubinsky, P., Havasiova-Reiterova, K., Petko, B., Hovorka, I. and Tomasovicova, O. (1995) Role of small mammals in the epidemiology of toxocariasis. Parasitology 110, 187-193.
24. Dunsmore, J.D., Thompson, R.C.A. and Bates, I.A. (1983) The accumulation of Toxocara canis larvae in the brains of mice. International Journal for Parasitology 13, 517-521.
25. Epe, C., Sabel, T., Schneider, T. and Stoye, M. (1994) The behaviour and pathogenicity of Toxocara canis larvae in mice of different strains. Parasitology Research 80, 691-695.
26. Evans, C.A.W., Garcia, H.H., Hartnell, A., Gilman, R.H., Jose, P.J., Martinez, M., Remick, D.G., Williams, T.J. and Friedland, J.S. (1998) Elevated concentrations of eotaxin and interleukin-5 in human neurocysticercosis. Infection and Immunity 66, 4522-4525.
27. Fenoy, S., Ollero, M.D., Guillen, J.F. and del Aguila, C. (2001) Animal models in ocular toxocariasis. Journal of Helminthology 75, 119-124.
28. Galvin, T.J. (1964) Experimental Toxocara canis infections in chickens and pigeons. Journal of Parasitology 50, 124-127.
29. Gazzinelli, R.T., Eltoum, I., Wynn, T.A. and Sher, A. (1993) Acute cerebral toxoplasmosis is induced by in vivo neutralization of TNF-a and correlates with the down-regulated expression of inducible nitric oxide synthase and other markers of macrophage activation. Journal of Immunology 151, 3672-3681.
30. Gillespie, S.H. (1993) The clinical spectrum of human toxocariasis. In: Lewis, J.W. and Maizels, R.M (eds) Toxocara and Toxocariasis. Institute of Biology and British Society for Parasitology, London, pp. 55-61.
31. Glickman, L.T. (1993) The epidemiology of human toxocariasis. In: Lewis, J.W. and Maizels, R.M (eds) Toxocara and Toxocariasis. Institute of Biology and British Society for Parasitology, London, pp. 3-10.
32. Glickman, L.T. and Schantz, P.M. (1981) Epidemiology of zoonotic toxocariasis. Epidemiologic Reviews 3, 230-250.
33. Glickman, L.T. and Summers, B.A. (1983) Experimental Toxocara canis infection in cynomolgus macaques (Macaca fascicularis). American Journal of Veterinary Research 44, 2347-2354.
34. Glickman, L.T., Cypress, R., Crumrine, P.K. and Gitlin, D.A. (1979) Toxocara infection and epilepsy in children. Journal of Paediatrics 94, 75-78.
35. Good, B., Holland, C.V., Taylor, M.R.H., Larragy, J., Moriarty, P. and O'Regan, M. (2004) Ocular toxocariasis in schoolchildren. Clinical Infectious Diseases 39, 173-178.
36. Grau, G.E., Fajardo, L.F., Piguet, P.F., Allet, B., Lambert, P.H. and Vassalli, P. (1987) Tumor necrosis factor (cachectin) as an essential mediator in murine cerebral malaria. Science 237, 1210-1212.
37. Grau, G.E., Piguet, P.F., Vassalli, P. and Lambert, P.H. (1989) Tumor-necrosis factor and other cytokines in cerebral malaria: experimental and clinical data. Immunological Reviews 112, 49-70.
38. Hamilton, C.M., Pinelli, E. and Holland, C.V. (2004) A murine model for cerebral toxocariasis: effect of larval burden on behaviour and immune response in two strains of inbred mice. In: Abstracts of the Proceedings of IX European Multicolloquium of Parasitology, Valencia, Spain, 18-23 July 2004, pp. 389-390.
39. Hay, J. and Aitken, P.P. (1984) Experimental toxocariasis in mice and its effect on their behaviour. Annals of Tropical Medicine and Parasitology 78, 145-155.
40. Hay, J., Aitken, P.P. and Arnott, M.A. (1985) The effect of Toxocara canis on the spontaneous running activity of mice. Annals of Tropical Medicine and Parasitology 79, 221-222.
41. Hay, J., Kendall, A.T., Aitken, P.P. and Arnott, M.A. (1986) Toxocara canis infection and hyperactivity. Annals of Tropical Medicine and Parasitology 80, 531-533.
42. Helwigh, A.B., Lind, P. and Nansen, P. (1999) Visceral larva migrans: migratory pattern of Toxocara canis in pigs. International Journal for Parasitology 29, 559-565.
43. Holland, C.V. and Cox, D.M. (2001) Toxocara in the mouse: a model for parasite-altered host behaviour? Journal of Helminthology 75, 125-135.
44. Hill, I.R., Denham, D.A. and Scholtz, C.L. (1985) Toxocara canis larvae in the brain of a British child. Transactions of the Royal Society of Tropical Medicine and Hygiene 79, 351-354.
45. Hunt, N.H. and Grau, G.E. (2003) Cytokines: accelerators and brakes in the pathogenesis of cerebral malaria. Trends in Immunology 24, 491-499.
46. Janeway, C.A., Travers, P., Walport, M. and Shlomchik, M. (2001) T cell-mediated immunity. In: Immunobiology: the Immune System in Health and Disease, 5th edn. Garland Publishing, Taylor and Francis Group, New York, pp. 295-340.
47. Jennings, V.M., Actor, J.K., Lal, A.A. and Hunter, R.L. (1997) Cytokine profile suggesting murine cerebral malaria is an encephalitis. Infection and Immunity 65, 4883-4887.
48. Kaplan, M., Kalkan, A., Hosoglu, S., Kuk, S., Özden, M., Demirdag, K. and Ozdarendeli, A. (2004) The frequency of Toxocara infection in mental retarded children. Memorias do Instituto Oswaldo Cruz 99, 121-125.
49. Kern, P., Hemmer, C.J., van Damme, J.V, Gruss, H.J. and Dietrich, M. (1989) Elevated tumor necrosis factor alpha and interleukin-6 serum levels as markers for complicated Plasmodium falciparum malaria. American Journal of Medicine 87, 139-143.
50. Kunishige, A. (1964) Histologic and histochemical studies on experimental 'visceral larva migrans' in rabbits and mice. Skikoku Acta Medica 21, 546-567.
51. Kuroda, E., Yoshida, Y., En Shan, B. and Yamashita, U. (2001) Suppression of macrophage interleukin-12 and tumour necrosis factor-alpha production in mice infected with Toxocara canis. Parasite Immunology 23, 305-11.
52. Magnaval, J-F., Galindo, V., Glickman, L.T. and Clanet, M. (1997) Human Toxocara infection of the central nervous system and neurological disorders: a case-control study. Parasitology 115, 537-543.
53. Maizels, R.M., Tetteh, K.K.A. and Loukas, A. (2000) Toxocara canis: genes expressed by the arrested infective larval stage of a parasitic nematode. International Journal of Parasitology 30, 495-508.
54. Marmor, M., Glickman, L., Shofer, F., Faich, L., Rosenberg, C., Cornblatt, B., and Friedman, S. (1987) Toxocara canis infection of children: epidemiologic and neuropsychologic findings. American Journal of Public Health 77, 554-559.
55. Moore, M.T. (1962) Human Toxocara canis encephalitis with lead encephalopathy. Journal of Neuropathology and Experimental Neurology 21, 201-218.
56. Moreira-Silva, S.F., Rodrigues, M.G., Pimenta, J.L., Gomes, C.P., Freire, L. and Pereira, E.L. (2004) Toxocariasis of the central nervous system: with report of two cases. Revista da Sociedade Brasileira de Medicina Tropical 37, 169-174.
57. Mosmann, T.R. and Coffman, R.L. (1987) Two types of mouse helper T-cell clone: implications for immune regulation. Immunology Today 8, 223-227.
58. Nagakura, K., Tachibana, H., Kaneda, Y., Kato, Y. (1989) Toxocariasis possibly caused by ingesting raw chicken. Journal of Infectious Diseases 160, 735-736.
59. Nakamura, S., Sotoyama, T., Hayasaka, S., Kameyama, Y., Maruyama, S., and Katsube. Y. (1991) Parasitism of Toxocara canis larvae in Japanese quails by inoculation of the ascarid eggs. Journal of Veterinary Medical Science 53, 865-872.
60. Okoshi, S. and Usui, M. (1968) Experimental studies on Toxascaris leonina: VI. Experimental infection of mice, chickens and earthworms with Toxascaris leonina, Toxocara canis and Toxocara cati. Japanese Journal of Veterinary Science 30, 151-166.
61. Olson, L.J. and Rose, J.E. (1966) Effect of Toxocara canis infection on the ability of white rats to solve maze problems. Experimental Parasitology 19, 77-84.
62. Restrepo, B.I., Llaguno, P., Sandoval, M.A., Enciso, J.A. and Teale, J.M. (1998) Analysis of immune lesions in neurocysticercosis patients: central nervous system response to helmith appears Th1-live instead of Th2. Journal of Neuroimmunology 89, 64-72.
63. Rodrigues, V., de-Mello, F.A., Magalhaes, E.P., Ribeiro, S.B.F. and Marquez, J.O. (2000) Interleukin-5 and interleukin-10 are major cytokines in cerebrospinal fluid from patients with active neurocysticercosis. Brazilian Journal of Medical and Biological Research 33, 1059-1063.
64. Rudin, W., Eugster, H.P., Bordmann, G., Bonato, J., Muller, M., Yamage, M. and Ryffel, B. (1997) Resistance to cerebral malaria in tumor necrosis factor-a/b-deficient mice is associated with a reduction of intracellular adhesion molecules-1 upregulation and T-helper type 1 response. American Journal of Tropical Medicine and Hygiene 62, 530-534.
65. Salem, G. and Schantz, P. (1992) Toxocaral visceral larva migrans after ingestion of raw lamb liver. Clinical Infectious Diseases 15, 743-744.
66. Sarciron, M.E. and Gherrardi, A. (2000) Cytokines involved in toxoplasmic encephalitis. Scandinavian Journal of Immunology 52, 534-543.
67. Sato, H., Matsuo, K., Osanai, A., Kamiya, H., Akao, N., Owaki, S. and Furuoka, H. (2004) Larva migrans by Baylisascaris transfuga: fatal neurological diseases in Mongolian jirds, but not in mice. Journal of Parasitology 90, 774-781.
68. Schluter, D., Kwok, L.Y., Lutjen, S., Soltek, S., Hoffmann, S., Korner, H. and Deckert, M. (2003) Both lymphotoxin-a and TNF are crucial for control of Toxoplasma gondii in the central nervous system. Journal of Immunology 170, 6172-6182.
69. Scott, P., Pearce, E., Cheever, A.W., Coffman, R.L. and Sher, A. (1989) Role of cytokines and CD4+ T-cell subsets in the regulation of parasite immunity and disease. Immunological Reviews 112, 161-182.
70. Shields, J.A. (1984) Ocular toxocariasis. A review. Ophthalmology 28, 361-381.
71. Skerrett, H., and Holland, C.V. (1997) Variation in the larval recovery of Toxocara canis from the murine brain: implications for behavioural studies. Journal of Helminthology 71, 253-255.
72. Sprent, J.F.A. (1955) On the invasion of the central nervous system by nematodes. II. Invasion of the nervous system in ascariasis. Parasitology 45, 41-55.
73. Summers, B., Cypess, R.H., Dolinksy, Z.S., Burright, R.G. and Donovick, P.J. (1983) Neuropathological studies of experimental toxocariasis in lead exposed mice. Brain Research Bulletin 10, 547-550.
74. Suzuki, Y. (2002a) Host resistance in the brain against Toxoplasma gondii. Journal of Infectious Diseases 185, S58-S65.
75. Suzuki, Y. (2002b) Immunopathogenesis of cerebral toxoplasmosis. Journal of Infectious Diseases 186, S234-S240.
76. Suzuki, Y., Kang, H., Parmley, S., Lim, S. and Park, D. (2000) Induction of tumor necrosis factor-a and inducible nitric oxide synthase fails to prevent toxoplasmic encephalitis in the absence of interferon-g in genetically resistant BALB/c mice. Microbes and Infection 2, 455-462.
77. Taira, K., Saeed, I., Lind, P., Murrell, K.D. and Kapel, C.M.O. (2003) Population dynamics of Toxocara canis in pigs receiving a single or multiple infection. Parasitology 127, 593-602.
78. Takayanagi, T.H., Akao, N., Suzuki, R., Tomoda,M., Tsukidate, S. and Fujita, K. (1999) New animal model for human ocular toxocariasis: ophthalmoscopic observation. British Journal of Ophthalmology 83, 967-972.
79. Taylor, M.R.H., Keane, C.T., O'Connor, P., Mulville, E. and Holland, C. (1988) The expanded spectrum of toxocaral disease. Lancet i, 692-695.
80. Wang, M.Q., Jiang, H.J., Inoue, H., Myozaki, M. and Yamashita U. (1995) B cell mitogenic activity of Toxocara canis adult worm antigen. Parasite Immunology 17, 609-15.
81. Wolfe, A. and Wright, I.P. (2003) Human toxocariasis and direct contact with dogs. Veterinary Record 152, 419-422.
82. Worley, G., Green, J.A., Frothingham, T.E., Sturner, R.A., Walls, K.W., Pakalnis, V.A. and Ellis Jr., G.S. (1984) Toxocara canis infections: clinical and epidemiological associations with seropositivity in kindergarten children. Journal of Infectious Diseases 149, 591-597.