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Volumn 73, Issue 1, 2008, Pages 112-115

Enantioselective production of 3-hydroxy metabolites of tibolone by yeast reduction

Author keywords

15 ,7 Methyl 19 norpregn 5(10) en 20 in 3 ,17 diol; 17 Hydroxy 7 methyl 19 norpregn 5(10) en 20 in 3 one; 7 Methyl 19 norpregn 5(10) en 20 in 3 ,17 diol; Enantioselective reduction; Kluyveromyces lactis; Saccharomyces cerevisiae; Tibolone

Indexed keywords

DRUG METABOLITE; TIBOLONE;

EID: 36849045141     PISSN: 0039128X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.steroids.2007.09.008     Document Type: Article
Times cited : (12)

References (8)
  • 2
    • 0031687747 scopus 로고    scopus 로고
    • A doubleblind, randomised trial comparing the effects of tibolone and continuous combined hormone replacement therapy in postmenopausal women with menopausal symptoms
    • Hammar M., Christau S., Nathorst-Boos J., Rud T., and Garre K. A doubleblind, randomised trial comparing the effects of tibolone and continuous combined hormone replacement therapy in postmenopausal women with menopausal symptoms. BJOG 105 (1998) 904-911
    • (1998) BJOG , vol.105 , pp. 904-911
    • Hammar, M.1    Christau, S.2    Nathorst-Boos, J.3    Rud, T.4    Garre, K.5
  • 3
    • 1842865611 scopus 로고    scopus 로고
    • A review of the effects of tibolone on the skeleton
    • Devogelaer J.P. A review of the effects of tibolone on the skeleton. Expert Opin Pharmacothr 5 (2004) 941-949
    • (2004) Expert Opin Pharmacothr , vol.5 , pp. 941-949
    • Devogelaer, J.P.1
  • 4
    • 0034987346 scopus 로고    scopus 로고
    • Tibolone: a steroid with a tissue-specific mode of action
    • Kloosterboer H.J. Tibolone: a steroid with a tissue-specific mode of action. J Steroid Biochem Mol Biol 76 (2001) 231-238
    • (2001) J Steroid Biochem Mol Biol , vol.76 , pp. 231-238
    • Kloosterboer, H.J.1
  • 7
    • 0037180573 scopus 로고    scopus 로고
    • A practical chemoenzymatic approach to the synthesis of 3-hydroxy metabolites of tibolone
    • Ferraboschi P., Colombo D., and -Elahi S.R. A practical chemoenzymatic approach to the synthesis of 3-hydroxy metabolites of tibolone. Tetrahedron: Asymmetry 13 (2002) 2583-2586
    • (2002) Tetrahedron: Asymmetry , vol.13 , pp. 2583-2586
    • Ferraboschi, P.1    Colombo, D.2    -Elahi, S.R.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.