Neuroprotective effects of riluzole in Huntington's disease [3]

European Journal of Nuclear Medicine and Molecular Imaging

Volumn 35, Issue 1, 2008, Pages 221-222

  Squitieri, Ferdinando ^a   Ciammola, Andrea ^b   Colonnese, Claudio ^a   Ciarmiello, Andrea ^c  

^a IRCCS NEUROMED   (Italy)

^b ISTITUTO AUXOLOGICO ITALIANO   (Italy)

^c NATIONAL CANCER INSTITUTE   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR; FLUORODEOXYGLUCOSE F 18; NEUROPROTECTIVE AGENT; PLACEBO; RILUZOLE;

ABSENCE OF SIDE EFFECTS; BRAIN SIZE; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED STUDY; DISEASE DURATION; DRUG EFFECT; DRUG MECHANISM; DRUG SAFETY; HUMAN; HUNTINGTON CHOREA; LETTER; MINI MENTAL STATE EXAMINATION; MOTONEURON; NEUROPROTECTION; NEUROTRANSMISSION; NUCLEAR MAGNETIC RESONANCE IMAGING; POSITRON EMISSION TOMOGRAPHY; PROTEIN BLOOD LEVEL; SINGLE BLIND PROCEDURE;

AGED; AGED, 80 AND OVER; BRAIN; CONTROLLED CLINICAL TRIALS AS TOPIC; FEMALE; FOLLOW-UP STUDIES; HUMANS; HUNTINGTON DISEASE; MALE; MIDDLE AGED; NEUROPROTECTIVE AGENTS; POSITRON-EMISSION TOMOGRAPHY; RILUZOLE;

EID: 36849032943     PISSN: 16197070     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00259-007-0615-y     Document Type: Letter

References (6)

1. Bergerot A, Shortland PJ, Anand P, et al. Co-treatment with riluzole and GDNF is necessary for functional recovery after ventral root avulsion injury. Exp Neurol 2004;187:359-66.
2. Katoh-Semba R, Asano T, Ueda H, et al. Riluzole enhances expression of brain-derived neurotrophic factor with consequent proliferation of granule precursor cells in the rat hippocampus. FASEB J 2002;16:1328-30.
3. Gauthier LR, Charrin BC, Borrell-Pages M, et al. Huntingtin controls neurotrophic support and survival of neurons by enhancing BDNF vesicular transport along microtubules. Cell 2004;118:127-38.
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5. Ciarmiello A, Cannella M, Lastoria S, et al. Brain white-matter volume loss and glucose hypometabolism precede the clinical symptoms of Huntington's disease. J Nucl Med 2006;47:215-22.
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