Acquisition of different carbapenem resistance mechanisms by an epidemic clonal lineage of Pseudomonas aeruginosa

Clinical Microbiology and Infection

Volumn 14, Issue 1, 2008, Pages 88-90

  Edalucci, E ^a   Spinelli, R ^a   Dolzani, L ^a   Riccio, M Letizia ^b   Dubois, V ^c   Tonin, E Angelo ^a   Rossolini, G M ^b   Lagatolla, C ^a  

^a UNIVERSITY OF TRIESTE   (Italy)

^b UNIVERSITY OF SIENA   (Italy)

^c University Victor Segalen   (France)

Author keywords

Carbapenem resistance; Clonal lineage; Metallo lactamase; Pseudomonas aeruginosa; Resistance acquisition; VIM 2

Indexed keywords

CARBAPENEM; IMIPENEM; MEROPENEM; METALLO BETA LACTAMASE; METALLO BETA LACTAMASE VIM 1; METALLO BETA LACTAMASE VIM 2; UNCLASSIFIED DRUG;

ANTIBIOTIC RESISTANCE; ARTICLE; BACTERIAL GENETICS; BACTERIAL STRAIN; BACTERIUM ISOLATE; CLONAL VARIATION; DNA DETERMINATION; EPIDEMIC; FRANCE; GENE CLUSTER; GENE DELETION; INTEGRON; ITALY; MINIMUM INHIBITORY CONCENTRATION; MOLECULAR CLONING; MULTILOCUS SEQUENCE TYPING; NONHUMAN; NUCLEOTIDE SEQUENCE; OPERON; PHYLOGENY; PRIORITY JOURNAL; PSEUDOMONAS AERUGINOSA; SEQUENCE HOMOLOGY;

PSEUDOMONAS AERUGINOSA;

EID: 36849026565     PISSN: 1198743X     EISSN: 14690691     Source Type: Journal    
DOI: 10.1111/j.1469-0691.2007.01874.x     Document Type: Article

References (19)

1. Rossolini GM, Mantengoli E. Treatment and control of severe infections caused by multiresistant Pseudomonas aeruginosa. Clin Microbiol Infect 2005; 11 (suppl 4): 17-32.
2. Poole K. Multidrug efflux pumps and antimicrobial resistance in Pseudomonas aeruginosa and related organisms. J Mol Microbiol Biotechnol 2001; 3: 255-264.
3. Pai H, Kim J, Kim J, Lee JH, Choe KW, Gotoh N. Carbapenem resistance mechanisms in Pseudomonas aeruginosa clinical isolates. Antimicrob Agents Chemother 2001; 45: 480-484.
4. Livermore DM. Of Pseudomonas, porins, pumps and carbapenems. J Antimicrob Chemother 2001; 47: 247-250.
5. Bush K. New beta-lactamases in gram-negative bacteria: Diversity and impact on the selection of antimicrobial therapy. Clin Infect Dis 2001; 32: 1085-1089.
6. Pirnay JP, De Vos D, Cochez C et al. Pseudomonas aeruginosa displays an epidemic population structure. Environ Microbiol 2002; 4: 898-911.
7. Curran B, Jonas D, Grundmann H, Pitt T, Dowson CG. Development of a multilocus sequence typing scheme for the opportunistic pathogen Pseudomonas aeruginosa. J Clin Microbiol 2004; 42: 5644-5649.
8. Giske CG, Libisch B, Colinon C et al. Establishing clonal relationships between VIM-1-like metallo-beta-lactamase-producing Pseudomonas aeruginosa strains from four European countries by multilocus sequence typing. J Clin Microbiol 2006; 44: 4309-4315.
9. Lagatolla C, Edalucci E, Dolzani L et al. Molecular evolution of metallo-beta-lactamase-producing Pseudomonas aeruginosa in a nosocomial setting of high-level endemicity. J Clin Microbiol 2006; 44: 2348-2353.
10. Epp SF, Pechere J, Kok M. Raising antibodies against OprD, an outer membrane protein of Pseudomonas aeruginosa using translational fusions to MalE. J Microbiol Meth 2001; 46: 1-8.
11. Epp SF, Kohler T, Plesiat P, Michea-Hamzehpour M, Frey J, Pechere JC. C-terminal region of Pseudomonas aeruginosa outer membrane porin OprD modulates susceptibility to meropenem. Antimicrob Agents Chemother 2001; 45: 1780-1787.
12. Dubois V, Arpin C, Melon M et al. Nosocomial outbreak due to a multiresistant strain of Pseudomonas aeruginosa P12: Efficacy of cefepime-amikacin therapy and analysis of beta-lactam resistance. J Clin Microbiol 2001; 39: 2072-2078.
13. Botes J, Williamson G, Sinickas V, Gurtler V. Genomic typing of Pseudomonas aeruginosa isolates by comparison of riboprinting and PFGE: correlation of experimental results with those predicted from the complete genome sequence of isolate PAO1. J Microbiol Meth 2003; 55: 231-240.
14. Grundmann H, Schneider C, Hartung D, Daschner FD, Pitt TL. Discriminatory power of three DNA-based typing techniques for Pseudomonas aeruginosa. J Clin Microbiol 1995; 33: 528-534.
15. Mahenthiralingam E, Campbell ME, Foster J, Lam JS, Speert DP. Random amplified polymorphic DNA typing of Pseudomonas aeruginosa isolates recovered from patients with cystic fibrosis. J Clin Microbiol 1996; 34: 1129-1135.
16. Levesque C, Piche L, Larose C, Roy PH. PCR mapping of integrons reveals several novel combinations of resistance genes. Antimicrob Agents Chemother 1995; 39: 185-191.
17. Caetano T, Ferreira S, Mondego AP, Correia A, Mendo S. In99, an In100-related integron, its occurrence and prevalence in clinical Pseudomonas aeruginosa strains from a central region of Portugal. Epidemiol Infect 2007; 135: 502-504.
18. Clinical and Laboratory Standards Institute. Performance standards for antimicrobial susceptibility testing, 16th informational supplement, M100-S16. Wayne, PA: CLSI, 2006.
19. Livermore DM. Bacterial resistance to carbapenems. Adv Exp Med Biol 1995; 390: 25-47.