Enhancement of transfection efficiency for HeLa cells via incorporating arginine moiety into chitosan

Chinese Science Bulletin

Volumn 52, Issue 23, 2007, Pages 3207-3215

  Zhu, DunWan ^a   Zhang, HaiLing ^b   Bai, JinGen ^a   Liu, WenGuang ^a   Leng, XiGang ^b   Song, CunXian ^b   Yang, Jian ^a   Li, XiaoWei ^a   Jin, Xu ^b   Song, LiPing ^b   Liu, LanXia ^b   Li, XiuLan ^c   Zhang, Yang ^c   Yao, KangDe ^a  

^a TIANJIN UNIVERSITY   (China)

^b INSTITUTE OF BIOMEDICAL ENGINEERING   (China)

^c TIANJIN HOSPITAL   (China)

Author keywords

Arginine modified chitosan; Arginine rich peptides; Chitosan; Gene delivery system; Non viral vector

Indexed keywords

EID: 36849026041     PISSN: 10016538     EISSN: 18619541     Source Type: Journal    
DOI: 10.1007/s11434-007-0455-y     Document Type: Article

References (40)

1. Jin H, Kim T H, Hwang S K, et al. Aerosol delivery of urocanic acid-modified chitosan/programmed cell death 4 complex regulated apoptosis, cell cycle, and angiogenesis in lungs of K-ras null mice. Mol Cancer Ther, 2006, 5(4): 1041-1049
2. Blau H, Khavari P. Gene therapy: Progress, problems, prospects. Nat Med, 1997, 3(6): 612-613
3. Curiel D T, Gerritsen W R, Krul M R. Progress in cancer gene therapy. Cancer Gene Ther, 2000, 7(8): 1197-1199
4. Gao X, Huang L. Potentiation of cationic liposome-mediated gene delivery by polycations. Biochemistry, 1996, 35(3): 1027-1036
5. Audouy S A, Leij L F, Hoekstra D, et al. In vivo characteristics of cationic liposomes as delivery vectors for gene therapy. Pharm Res, 2002, 19(11): 1599-1605
6. Choi Y H, Liu F, Park J S, et al. Lactose-poly(ethylene glycol)-grafted poly-L-lysine as hepatoma cell-tapgeted gene carrier. Bioconjug Chem, 1998, 9(6): 708-718
7. Lungwitz U, Breunig M, Blunk T, et al. Polyethylenimine-based nonviral gene delivery systems. Eur J Pharm Biopharm, 2005, 60(2): 247-266
8. Boussif O, Lezoualch F, Zanta M A, et al. A versatile vector for gene and oligonucleotide transfer into cells in culture and in vivo: polyethylenimine. Proc Natl Acad Sci USA, 1995, 92(16): 7297-7301
9. Zhang X Q, Wang X L, Huang S W, et al. In vitro gene delivery using polyamidoamine dendrimers with a trimesyl core. Biomacromolecules, 2005, 6(1): 341-350
10. Braun C S, Vetro J A, Tomalia D A, et al. Structure/function relationships of polyamidoamine/DNA dendrimers as gene delivery vehicles. J Pharm Sci, 2005, 94(2): 423-436
11. Truong-Le V L, August J T, Leong K W. Controlled gene delivery by DNA-gelatin nanospheres. Hum Gene Ther, 1998, 9(12): 1709-1717
12. Liu W G, Yao K D. Chitosan and its derivatives-A promising non-viral vector for gene transfection. J Contr Rel, 2002, 83(1): 1-11
13. Liu W G, Sun S J, Cao Z Q, et al. An investigation on the physicochemical properties of chitosan/DNA polyelectrolyte complexes. Biomaterials, 2005, 26(15): 2705-2711
14. Leong K W, Mao H Q, Truong-Le V L, et al. DNA-polycation nanospheres as non-viral gene delivery vehicles. J Contr Rel, 1998, 53(1-3): 183-193
15. Garnett M C. Gene-delivery systems using cationic polymers. Crit Rev Ther Drug Carrier Syst, 1999, 16(2): 147-207
16. Erbacher P, Zou S, Bettinger T, et al. Chitosan-based vector/DNA complexes for gene delivery: Biophysical characteristics and transfection ability. Pharm Res, 1998, 15(9): 1332-1339
17. MacLaughlin F C, Mumper R J, Wang J, et al. Chitosan and depolymerized chitosan oligomers as condensing carriers for in vivo plasmid delivery. J Contr Rel, 1998, 56(1-3): 259-272
18. Richardson S C, Kolbe H V, Duncan R. Potential of low molecular mass chitosan as a DNA delivery system: Biocompatibility, body distribution and ability to complex and protect DNA. Int J Pharm, 1999, 178(2): 231-243
19. Mumper R J, Wang J, Claspel J M, et al. Novel polymeric condensing carriers for gene delivery. Proc Intl Symp Contr Rel Bioact Mater, 1995, 22: 178-179
20. Park I K, Kim T H, Park Y H, et al. Galactosylated chitosan- graftpoly(ethylene glycol) as hepatocyte-targeting DNA carrier. J Contr Rel, 2001, 76(3): 349-362
21. Liu W G, Zhang X, Sun S J, et al. N-alkylated chitosan as a potential nonviral vector for gene transfection. Bioconjug Chem, 2003, 14(4): 782-789
22. Li F, Liu W G, Yao K D. Preparation of oxidized glucose-crosslinked N-alkylated chitosan membrane and in vitro studies of pH-sensitive drug delivery behaviour. Biomaterials, 2002, 23(2): 343-347
23. Kim Y H, Gihm S H, Park C R, et al. Structural characteristics of size-controlled self-aggregates of deoxycholic acid-modified chitosan and their application as a DNA delivery carrier. Bioconjug Chem, 2001, 12(6): 932-938
24. Kiang T, Wen J, Lim H W, et al. The effect of the degree of chitosan deacetylation on the efficiency of gene transfection. Biomaterials, 2004, 25(22): 5293-5301
25. Becker H M, McAllister S S, Dowdy S F. TAT-mediated protein transduction into mammalian cells. Methods, 2001, 24(3): 247-256
26. Derossi D, Joliot A H, Chassaing G, et al. The third helix of the Antennapedia homeodomain translocates through biological membranes. J Biol Chem, 1994, 269(14): 10444-10450
27. Phelan A, Elliott G, O'Hare P. Intercellular delivery of functional p53 by the herpesvirus protein VP22. Nat Biotech, 1998, 16(5): 440-443
28. Vives E, Brodin P, Lebleu B. A truncated HIV-1 Tat protein basic domain rapidly translocates through the plasma membrane and accumulates in the cell nucleus. J Biol Chem, 1997, 272(25): 16010-16017
29. Elliott G, O'Hare P. Intercellular trafficking and protein delivery by a herpesvirus structural protein. Cell, 1997, 88(2): 223-233
30. Derossi D, Chassaing G, Prochiantz A. Trojan peptides: the penetratin system for intracellular delivery. Trends Cell Biol, 1998, 8(2): 84-87
31. Brooks H, Lebleu B, Vives E. Tat peptide-mediated cellular delivery: Back to basics. Adv Drug Deliv Rev, 2005, 57(4): 559-577
32. Liu W G, Zhang J R, Cao Z Q, et al. A chitosan-arginine conjugate as a novel anticoagulation biomaterial. J Mater Sci Mater Med, 2004, 15(11): 1199-1203
33. Mao H Q, Roy K, Troung-Le V L, et al. Chitosan-DNA nanoparticles as gene carriers: Synthesis, characterization and transfection efficiency. J Contr Rel, 2001, 70(3): 399-421
34. Smith P K, Krohn R I, Hermanson G T, et al. Measurement of protein using bicinchoninic acid. Anal Biochem, 1985, 150(1): 76-85
35. Lavertu M, Methot S, Tran-Khanh N, et al. High efficiency gene transfer using chitosan/DNA nanoparticles with specific combinations of molecular weight and degree of deacetylation. Biomaterials, 2006, 27(27): 4815-4824
36. Bozkir A, Saka O M. Chitosan nanoparticles for plasmid DNA delivery: Effect of chitosan molecular structure on formulation and release characteristics. Drug Deliv, 2004, 11(2): 107-112
37. Umezawa N, Gelman M A, Haigis M C, et al. Translocation of a betapeptide across cell membranes. J Am Chem Soc, 2002, 124(3): 368-369
38. Mitchell D J, Kim D T, Steinman L, et al. Polyarginine enters cells more efficiently than other polycationic homopolymers. J Pept Res, 2000, 56(5): 318-325
39. Calnan B J, Tidor B, Biancalana S, et al. Arginine-mediated RNA recognition: The arginine fork. Science, 1991, 252(5010): 1167-1171
40. Zhang H L, Zhu D W, Yang J, et al. Cellular uptake and cytotoxicity of modified chitosan as gene carriers. Acta Acad Med Sin (in Chinese), 2006, 29(4): 486-491