A randomized comparison of amiodarone and class IC antiarrhythmic drugs to treat atrial fibrillation in patients paced for sinus node disease: The Prevention Investigation and Treatment: A Group for Observation and Research on Atrial arrhythmias (PITAGORA) trial

American Heart Journal

Volumn 155, Issue 1, 2008, Pages 100.e1-100.e9

  Gulizia, Michele ^a   Mangiameli, Salvatore ^b   Orazi, Serafino ^c   Chiarandà, Giacomo ^d   Piccione, Guglielmo ^e   Di Giovanni, Nicolò ^f   Colletti, Andrea ^g   Pensabene, Orazio ^h   Lisi, Francesco ⁱ   Vasquez, Ludovico ^j   Grammatico, Andrea ^k   Boriani, Giuseppe ^l  

^a Garibaldi Nesima Hospital   (Italy)

^b GARIBALDI HOSPITAL   (Italy)

^c SAN CAMILLO DE LELLIS HOSPITAL   (Italy)

^d Muscatello Hospital   (United States)

^e Civile Hospital   (Italy)

^f Abele Aiello Hospital   (Italy)

^g Civili Riuniti Hospital   (Italy)

^h Hospital Villa Sofia   (Italy)

ⁱ CANNIZZARO HOSPITAL   (Italy)

^j Civile Hospital   (Italy)

^k Medtronic Italia   (Italy)

^l UNIVERSITY OF BOLOGNA   (Italy)

more..

Author keywords

[No Author keywords available]

Indexed keywords

AMIODARONE; FLECAINIDE; PROPAFENONE; SOTALOL;

AGED; ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; FEMALE; FOLLOW UP; HEART ATRIUM ARRHYTHMIA; HEART ATRIUM FIBRILLATION; HEART PACING; HUMAN; KAPLAN MEIER METHOD; MAJOR CLINICAL STUDY; MALE; MORTALITY; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; SINUS NODE DISEASE;

EID: 36849025610     PISSN: 00028703     EISSN: 10976744     Source Type: Journal    
DOI: 10.1016/j.ahj.2007.08.033     Document Type: Article

References (31)

1. Narayan S.M., Cain M.E., and Smith J.M. Atrial fibrillation. Lancet 350 (1997) 943-950
2. Wolf P.A., Benjamin E.J., Belanger A.J., et al. Secular trends in the prevalence of atrial fibrillation. The Framingham study. Am Heart J 131 (1996) 790-795
3. Wolf P.A., Abbott R.D., and Kannel W.B. Atrial fibrillation as an independent risk factor for stroke: the Framingham Study. Stroke 22 (1991) 983-988
4. Benjamin E.J., D'Agostino R.B., Belanger A.J., et al. Left atrial size and the risk of stroke and death. The Framingham Heart Study. Circulation 92 (1995) 835-841
5. Andersen H.R., Thuesen L., Baggar J.P., et al. Prospective randomized trial of atrial versus ventricular pacing in sick sinus syndrome. Lancet 344 (1994) 1523-1528
6. Connolly S.J., Kerr C.R., Gent M., et al. Effects of physiologic pacing versus ventricular pacing on the risk of stroke and death due to cardiovascular causes. N Engl J Med 342 (2000) 1385-1391
7. Lamas G.A., Lee K.L., Sweeney M.O., et al. Ventricular pacing or dual chamber pacing for sinus node dysfunction. N Engl J Med 346 (2002) 1854-1860
8. Falk R.H. Atrial fibrillation. N Engl J Med 344 (2001) 1067-1078
9. Blomstrom-Lundqvist C., Scheinman M.M., Aliot E.M., et al. ACC/AHA/ESC guidelines for the management of patients with supraventricular arrhythmias. Circulation 108 (2003) 1871-1909
10. Kochiadakis G.E., Igoumenidis N.E., Marketou M.E., et al. Low-dose amiodarone versus sotalol for suppression of recurrent symptomatic AF. Am J Cardiol 81 (1998) 995-998
11. Roy D., Talajic M., Dorian P., et al. Amiodarone to prevent recurrence of atrial fibrillation. N Engl J Med 342 (2000) 913-920
12. The AFFIRM first antiarrhythmic drug substudy investigators. Maintenance of sinus rhythm in patients with atrial fibrillation. An AFFIRM substudy of the first antiarrhythmic drug. J Am Coll Cardiol 42 (2003) 20-29
13. Kochiadakis G.E., Igoumenidis N.E., Hamilos M.I., et al. Long-term maintenance of normal sinus rhythm in patients with current symptomatic atrial fibrillation. Chest 125 (2004) 377-383
14. Gold R.L., Haffajee C.I., Charos G., et al. Amiodarone for refractory atrial fibrillation. Am J Cardiol 57 (1986) 124-127
15. Vorperian V.R., Havighurst T.C., Miller S., et al. Adverse effects of low dose amiodarone: a meta-analysis. J Am Coll Cardiol 30 (1997) 791-798
16. Amiodarone Trials Meta-Analysis Investigators. Effect of prophylactic amiodarone on mortality after acute myocardial infarction and in congestive heart failure: meta-analysis of individual data from 6500 patients in randomised trials. Lancet 350 (1997) 1417-1424
17. Israel C.W., Gronefeld G., Ehrlich J.R., et al. Long-term risk of recurrent atrial fibrillation as documented by an implantable monitoring device. J Am Coll Cardiol 43 (2004) 47-52
18. Glotzer T.V., Hellkamp A.S., Zimmerman J., et al. Atrial high rate episodes detected by pacemaker diagnostics predict death and stroke. Circulation 107 (2003) 1614-1619
19. Capucci A., Santini M., Padeletti L., et al. Monitored atrial fibrillation duration predicts arterial embolic events in patients suffering from bradycardia and atrial fibrillation implanted with antitachycardia pacemakers. J Am Coll Cardiol 46 (2005) 1913-1920
20. Gulizia M., Mangiameli S., Chiaranda G., et al. Design and rationale of a randomized study to compare amiodarone and class IC antiarrhythmic drugs in terms of atrial fibrillation treatment efficacy in patients paced for sinus node disease: the PITAGORA trial. Europace 8 (2006) 302-305
21. Gomberg-Maitland M., Frison L., and Halperin J.L. Active-control clinical trials to establish equivalence or noninferiority: methodological and statistical concepts linked to quality. Am Heart J 146 (2003) 398-403
22. Siegel J.P. Equivalence and noninferiority trials. Am Heart J 139 (2000) S166-S170
23. Gallagher M.M., and Camm A.J. Classification of atrial fibrillation. Pacing Clin Electrophysiol 20 (1997) 1603-1605
24. Gage B.F., Waterman A.D., Shannon W., et al. Validation of clinical classification schemes for predicting stroke: results from the National Registry of Atrial Fibrillation. JAMA 285 (2001) 2864-2870
25. Hinkle Jr. L.E., and Thaler H.T. Clinical classification of cardiac deaths. Circulation 65 (1982) 457-464
26. Israel C.W., Hugl B., Unterberg C., et al. Pace-termination and pacing for prevention of atrial tachyarrhythmias: results from a multicenter study with an implantable device for atrial therapy. J Cardiovasc Electrophysiol 12 (2001) 1121-1128
27. Brignole M., Menozzi C., Gasparini M., et al. An evaluation of the strategy of maintenance of sinus rhythm by antiarrhythmic drug therapy after ablation and pacing therapy in patients with paroxysmal atrial fibrillation. Eur Heart J 23 (2002) 892-900
28. Boriani G., Padeletti L., Santini M., et al. Predictors of atrial antitachycardia pacing efficacy in patients affected by brady-tachy form of sick sinus syndrome and implanted with a DDDRP device. J Cardiovasc Electrophysiol 16 (2005) 714-723
29. Scholten M.F., Thornton A.S., Mekel J.M., et al. Anticoagulation in atrial fibrillation and flutter. Europace 7 (2005) 492-499
30. Lakshminarayan K., Solid C.A., Collins A.J., et al. Atrial fibrillation and stroke in the general Medicare population: a 10-year perspective (1992 to 2002). Stroke 37 (2006) 1969-1974
31. Benditt D.G., Williams J.H., Jin J., et al. Maintenance of sinus rhythm with oral d,l-sotalol therapy in patients with symptomatic atrial fibrillation and/or atrial flutter. d,l-Sotalol Atrial Fibrillation/Flutter Study Group. Am J Cardiol 84 (1999) 270-277