Retinol (vitamin A) and retinol-binding protein levels are decreased in ankylosing spondylitis: Clinical and genetic analysis

Journal of Rheumatology

Volumn 34, Issue 12, 2007, Pages 2457-2459

  O'Shea, Finbar D ^a,b   Tsui, Florence W L ^a,c   Chiu, Basil ^a,c   Tsui, Hing Wo ^a,c   Yazdanpanah, Mehrdad ^a,d   Inman, Robert D ^a,b,c  

^a UNIVERSITY HEALTH NETWORK   (Canada)

^b TORONTO WESTERN HOSPITAL   (Canada)

^c UNIVERSITY HEALTH NETWORK   (Canada)

^d TORONTO GENERAL HOSPITAL   (Canada)

Author keywords

Ankylosing spondylitis; Disease activity; Genetic studies; Retinol; Retinol binding protein

Indexed keywords

C REACTIVE PROTEIN; RETINOL; RETINOL BINDING PROTEIN;

ADULT; ANKYLOSING SPONDYLITIS; ARTICLE; CLINICAL ARTICLE; DISEASE ASSOCIATION; ENZYME LINKED IMMUNOSORBENT ASSAY; ERYTHROCYTE SEDIMENTATION RATE; FEMALE; GENETIC ANALYSIS; HUMAN; MALE; MASS SPECTROMETRY; PRIORITY JOURNAL; SINGLE NUCLEOTIDE POLYMORPHISM;

ADULT; AGED; CASE-CONTROL STUDIES; CYTOCHROME P-450 ENZYME SYSTEM; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; HUMANS; MALE; MASS SPECTROMETRY; MIDDLE AGED; POLYMORPHISM, SINGLE NUCLEOTIDE; RETINOL-BINDING PROTEINS, PLASMA; SPONDYLITIS, ANKYLOSING; VITAMIN A;

EID: 36849024553     PISSN: 0315162X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (16)

1. Nesher G, Zuckner J. Rheumatologic complications of vitamin A and retinoids. Semin Arthritis Rheum 1995;24:291-6.
2. DiGiovanna JJ. Isotretinoin effects on bone. J Am Acad Dermatol 2001;45:S176-82.
3. Liden M, Eriksson U. Understanding retinol metabolism: structure and function of retinol dehydrogenases. J Biol Chem 2006;281:13001-4.
4. Nebert DW, Russell DW. Clinical importance of the cytochromes P450. Lancet 2002;360:1155-62.
5. Perlmann T. Retinoid metabolism: a balancing act. Nat Genet 2002;31:7-8.
6. van der Linden S, Valkenburg HA, Cats A. Evaluation of diagnostic criteria for ankylosing spondylitis. A proposal for modification of the New York criteria. Arthritis Rheum 1984;27:361-8.
7. Dougados M, Leporho MA, Esmilaire L, Elaiba F, Amor B. Plasma levels of vitamins A and E in hyperostosis, ankylosing spondylarthritis and rheumatoid polyarthritis. Rev Rhum Mal Osteoartic 1988;55:251-4.
8. Mezes M, Bartosiewicz G, Nemeth J. Comparative investigations on vitamin A level of plasma in some rheumatic diseases. Clin Rheumatol 1986;5:221-4.
9. Penniston KL, Tanumihardjo SA. The acute and chronic toxic effects of vitamin A. Am J Clin Nutr 2006;83:191-201.
10. Lim LS, Harnack LJ, Lazovich D, Folsom AR. Vitamin A intake and the risk of hip fracture in postmenopausal women: the Iowa Women's Health Study. Osteoporos Int 2004;15:552-9.
11. Michaelsson K, Lithell H, Vessby B, Melhus H. Serum retinol levels and the risk of fracture. N Engl J Med 2003;348:287-94.
12. Feskanich D, Singh V, Willett WC, Colditz GA. Vitamin A intake and hip fractures among postmenopausal women. JAMA 2002;287:47-54.
13. Graham TE, Yang Q, Bluher M, et al. Retinol-binding protein 4 and insulin resistance in lean, obese, and diabetic subjects. N Engl J Med 2006;354:2552-63.
14. Carter KW, Pluzhnikov A, Timms AE, et al. Combined analysis of three whole genome linkage scans for ankylosing spondylitis. Rheumatology Oxford 2007;46:763-71.
15. Meigs JB, Panhuysen CI, Myers RH, Wilson PW, Cupples LA. A genome-wide scan for loci linked to plasma levels of glucose and HbA(1c) in a community-based sample of Caucasian pedigrees: The Framingham Offspring Study. Diabetes 2002;51:833-40.
16. Rat E, Billaut-Laden I, Allorge D, et al. Evidence for a functional genetic polymorphism of the human retinoic acid-metabolizing enzyme CYP26A1, an enzyme that may be involved in spina bifida. Birth Defects Res A Clin Mol Teratol 2006;76:491-8.