Multilayer PVA adsorption onto hydrophobic drug substrates to engineer drug-rich microparticles

European Journal of Pharmaceutical Sciences

Volumn 33, Issue 1, 2008, Pages 20-28

  Buttini, F ^a   Soltani, A ^b   Colombo, P ^a   Marriott, C ^b   Jones, S A ^b  

^a UNIVERSITY OF PARMA   (Italy)

^b KING'S COLLEGE LONDON   (United Kingdom)

Author keywords

Adsorption; Drug delivery; Microparticles; Poly(vinyl alcohol)

Indexed keywords

BETAMETHASONE VALERATE; BUDESONIDE; POLYVINYL ALCOHOL;

ARTICLE; DRUG ADSORPTION; DRUG DELIVERY SYSTEM; DRUG STRUCTURE; DRUG SYNTHESIS; HYDROLYSIS; HYDROPHOBICITY; ISOTHERM; MOLECULAR WEIGHT; PRIORITY JOURNAL; SURFACE PROPERTY;

ADRENAL CORTEX HORMONES; ADSORPTION; ALGORITHMS; BETAMETHASONE 17-VALERATE; BUDESONIDE; CALIBRATION; COLORIMETRY; FREEZE DRYING; HYDROLYSIS; HYDROPHOBICITY; KINETICS; MICROSPHERES; MOLECULAR WEIGHT; PARTICLE SIZE; PHARMACEUTICAL PREPARATIONS; POLYMERS; POLYVINYL ALCOHOL; SOLUBILITY; TECHNOLOGY, PHARMACEUTICAL; THERMODYNAMICS;

EID: 36849019024     PISSN: 09280987     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejps.2007.09.008     Document Type: Article

References (37)

1. Ariko N.G., and Agabekov V.E. Potassium iodide in coloring of polyvinyl alcohol film in oxidizing solution. Russ. J. Appl. Chem. 76 (2003) 1669-1673
2. Bagchi P. Theory of stabilization of spherical colloidal particles by non-ionic polymers. J. Colloid Interf. Sci. 47 (1973) 86-99
3. Boury F., Ivanova T., Panaiotov I., Proust J.E., Bois A., and Richou J. Dynamic properties of poly(dl-lactide) and polyvinyl-alcohol monolayers at the air-water and dichloromethane water interfaces. J. Colloid Interf. Sci. 169 (1995) 380-392
4. Briggner L.E., Buckton G., Bystrom K., and Darcy P. The use of isothermal microcalorimetry in the study of changes in crystallinity induced during the processing of powders. Int. J. Pharm. 105 (1994) 125-135
5. Buttini, F., Colombo, P., Wenger, M., Marriott, C., Jones, S.A., in press. Back to Basics: The development of a simple, homogenious, two-component dry powder inhaler for the delivery of budesonide using miscible vinyl polymers. J. Pharm. Sci. doi:10.1002/jps.21126.
6. Chew N.Y.K., and Chan H.K. Use of solid corrugated particles to enhance powder aerosol performance. Pharm. Res. 18 (2001) 1570-1577
7. Chiellini E., Corti A., Politi B., and Solaro R. Adsorption/desorption of polyvinyl alcohol on solid substrates and relevant biodegradation. J. Polym. Environ. 8 (2000) 67-79
8. Chikhalia V., Forbes R.T., Storey R.A., and Ticehurst M. The effect of crystal morphology and mill type on milling induced crystal disorder. Eur. J. Pharm. Sci. 27 (2006) 19-26
9. Choi Y.S., and Miyasaka K. Structure of poly(vinyl alcohol)-iodine complex formed in the amorphous phase of poly(vinyl alcohol) films. J. Appl. Polym. Sci. 48 (1993) 313-317
10. Edwards D.A., Hanes J., Caponetti G., Hrkach J., BenJebria A., Eskew M.L., Mintzes J., Deaver D., Lotan N., and Langer R. Large porous particles for pulmonary drug delivery. Science 276 (1997) 1868-1871
11. Finley J.H. Spectrophotometric determination of polyvinyl alcohol in paper coatings. Anal. Chem. 33 (1961) 1925-1927
12. Florence A.T., and Attwood D. Physicochemical Principles of Pharmacy. 3rd ed. (1998), Macmillan Press Ltd., London
13. Greenland D.J. Adsorption of polyvinyl alcohols by montmorillonite. J. Colloid Sci. 18 (1963) 647-664
14. Hajratwala B.R. Potential errors in determining Freundlich and Langmuir constants from adsorption isotherms. J. Pharm. Sci. 71 (1982) 125-126
15. Higuchi W. Diffusion models useful in biopharmaceutics. J. Pharm. Sci. 56 (1967) 315-324
16. ICH Steering Committee Validation of analytical procedures: methodology Q2B, 1996. Ref Type: Conference Proceeding.
17. Jones S.A., Brown M.B., and Martin G.P. Determination of polyvinyl alcohol using gel filtration chromatography. Chromatographia 59 (2004) 43-46
18. Jones S.A., Martin G.P., and Brown M.B. Biocompatible polymer blends: the effects of physical processing on the molecular interaction of polyvinyl alcohol and polyvinylpyrrolidone. J. Appl. Polym. Sci. 98 (2005) 2290-2299
19. Jones S.A., Martin G.P., and Brown M.B. Manipulation of beclomethasone-hydrofluoroalkane interactions using biocompatible macromolecules. J. Pharm. Sci. 95 (2006) 1060-1073
20. Jones S.A., Martin G.P., and Brown M.B. Manipulation of DNase I-hydrofluoroalkane interactions using biocompatible vinyl polymers. J. Cont. Rel. 115 (2006) 1-8
21. Levan M.D., and Vermeulen T. Binary Langmuir and Freundlich isotherms for ideal adsorbed solutions. J. Phys. Chem. 85 (1981) 3247-3250
22. Lyoo W.S., and Lee H.W. Synthesis of high-molecular-weight poly(vinyl alcohol) with high yield by novel one-batch suspension polymerization of vinyl acetate and saponification. Colloid Polym. Sci. 280 (2002) 835-840
23. Lyoo W.S., Yeum J.H., Ghim H.D., Park J.M., Lee S.J., Kim J.H., Shin D.Y., and Lee J.W. Effect of the molecular weight of poly(vinyl alcohol) on the water stability of a syndiotactic poly(vinyl alcohol)/iodine complex film. Colloid Polym. Sci. 281 (2003) 416-422
24. Mackin L., Sartnurak S., Thomas I., and Moore S. The impact of low levels of amorphous material (<5%) on the blending characteristics of a direct compression formulation. Int. J. Pharm. 231 (2002) 213-226
25. Miller J.N., and Miller J.C. Statistics for Analyitcal Chemistry (1993), Ellis Horwood, Chicherster/New York 101 pp
26. Miyasaka K. VA-iodine complexes-formation, structure, and properties. Adv. Polym. Sci. 108 (1993) 91-129
27. Napper D.H. Flocculation studies of non-aqueous sterically stabilized dispersions ofpolymer. Trans. Faraday Soc. 64 (1968) 1701
28. Nguyen D.T. Determination of equilibrium surface energy of adsorbed polyvinyl alcohol layers in water at 25 °C. Colloids Surf. Physicochem. Eng. Aspect 116 (1996) 145-160
29. Noguchi H., Jodai H., Yamaura K., and Matsuzawa S. Formation of poly(vinyl alcohol) iodine complex in aqueous solution: a SEM study of the freeze-dried substances. Polym. Int. 47 (1998) 428-432
30. Noguchi H., Jyodai H., and Matsuzawa S. Formation of poly(vinyl alcohol) iodine complexes in solution. J. Polym. Sci. B 35 (1997) 1701-1709
31. Overhoff K.A., Engstrom J.D., Chen B., Scherzer B.D., Milner T.E., Johnston K.P., and Williams III R.O. Novel ultra-rapid freezing particle engineering process for enhancement of dissolution rates of poorly water-soluble drugs. Eur. J. Pharm. Biopharm. 65 (2007) 57-67
32. Palakodaty S., York P., and Pritchard J. Supercritical fluid processing of materials from aqueous solutions: the application of SEDS to lactose as a model substance. Pharm. Res. 15 (1998) 1835-1843
33. Rehman M., Shekunov B.Y., York P., Lechuga-Ballesteros D., Miller D.P., Tan T., and Colthorpe P. Optimisation of powders for pulmonary delivery using supercritical fluid technology. Eur. J. Pharm. Sci. 22 (2004) 1-17
34. Rogers T.L., Nelsen A.C., Sarkari M., Young T.J., Johnston K.P., and Williams R.O. Enhanced aqueous dissolution of a poorly water soluble drug by novel particle engineering technology: spray-freezing into liquid with atmospheric freeze-drying. Pharm. Res. 20 (2003) 485-493
35. Stromber R.R., Tutas D.J., and Passaglia E. Conformation of polystyrene adsorbed at theta-temperature. J. Phys. Chem. 69 (1965) 3955
36. Zerfa M., and Brooks B.W. Experimental investigation of PVA adsorption at the vinyl chloride water interface in monomer suspensions. Colloid Surf. Physicochem. Eng. Aspect 132 (1998) 267-273
37. Zwick M.M. The blue complexes of iodine with poly(vinyl alcohol) and amylose. J. Polym. Sci. 4 (1966) 1642-1644