Defects in homocysteine metabolism: Diversity among hyperhomocyst(e)inemias

Clinical Chemistry and Laboratory Medicine

Volumn 45, Issue 12, 2007, Pages 1700-1703

  Matthews, Rowena G ^a,b   Elmore, C Lee ^a  

^a UNIVERSITY OF MICHIGAN   (United States)

^b UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

Author keywords

Adenosylhomocysteine; Adenosylmethionine; Cystathionine synthase; Folate; Genetic mouse models; Homocysteine; Methionine synthase; Methionine synthase reductase; Methylenetetrahydrofolate reductase

Indexed keywords

5 METHYLTETRAHYDROFOLIC ACID; 5,10 METHYLENETETRAHYDROFOLATE REDUCTASE (FADH2); CYSTATHIONINE BETA SYNTHASE; HOMOCYSTEINE; METHIONINE; METHIONINE SYNTHASE REDUCTASE; S ADENOSYLHOMOCYSTEINE; S ADENOSYLMETHIONINE;

ABNORMALLY LOW SUBSTRATE CONCENTRATION IN BLOOD; AMINO ACID BLOOD LEVEL; AMINO ACID METABOLISM; CONFERENCE PAPER; ENZYME ACTIVITY; ENZYME DEFICIENCY; EXPERIMENTAL MOUSE; FOLATE METABOLISM; GENETIC MODEL; HUMAN; HYPERHOMOCYSTEINEMIA; HYPOMETHIONINEMIA; LETHALITY; LIVER LEVEL; NEURAL TUBE DEFECT; NONHUMAN; PRIORITY JOURNAL; WILD TYPE;

ANIMALS; HOMOCYSTEINE; HUMANS; HYPERHOMOCYSTEINEMIA; MICE; MODELS, ANIMAL;

MURINAE; MUS;

EID: 36849018557     PISSN: 14346621     EISSN: 14374331     Source Type: Journal    
DOI: 10.1515/CCLM.2007.324     Document Type: Conference Paper

References (3)

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2. Mudd SH, Levy HL, Skovby F. Disorders of transsulfuration. In: Scriver CR, Beaudet AL, Sly WS, Valle D, editors. The metabolic and molecular bases of inherited disease, vol. 1, 7th ed. New York: McGraw Hill, 1995:1279-327.
3. The Heart Outcomes Prevention Evaluation (HOPE) 2 Investigators. Homocysteine lowering with folic acid and B vitamins in vascular disease. N Engl J Med 2006;354:1567-77.