The impact of conventional and heavy ion irradiation on tumor cell migration in vitro

International Journal of Radiation Biology

Volumn 83, Issue 11-12, 2007, Pages 889-896

  Goetze, K ^a   Scholz, M ^b   Taucher Scholz, G ^b   Mueller Klieser, W ^a  

^a JOHANNES GUTENBERG UNIVERSITY   (Germany)

^b GSI HELMHOLTZZENTRUM FÜR SCHWERIONENFORSCHUNG GMBH   (Germany)

Author keywords

1 integrin; 3 integrin; Heavy ion; Irradiation; Tumor cell migration

Indexed keywords

BETA1 INTEGRIN; BETA3 INTEGRIN; CARBON;

ARTICLE; CELL MIGRATION; CELL MOTILITY; CELL STRAIN HCT116; CONTROLLED STUDY; HEAVY ION RADIATION; HUMAN; HUMAN CELL; IN VITRO STUDY; IRRADIATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; TUMOR CELL; WESTERN BLOTTING; X IRRADIATION;

ANTIGENS, CD29; CELL LINE, TUMOR; CELL MOVEMENT; COLONIC NEOPLASMS; DOSE-RESPONSE RELATIONSHIP, RADIATION; GLIOMA; HEAVY IONS; HUMANS; INTEGRIN BETA3; NEOPLASM METASTASIS; NEOPLASMS;

EID: 36849013020     PISSN: 09553002     EISSN: 13623095     Source Type: Journal    
DOI: 10.1080/09553000701753826     Document Type: Article

References (18)

1. Abdollahi A, Griggs DW, Zieher H, Roth A, Lipson KE, Saffrich R, Grone HJ, Hallahan DE, Reisfeld RA, Debus J, Niethammer AG, Huber PE. 2005. Inhibition of alpha(v) beta3 integrin survival signaling enhances antiangiogenic and antitumor effects of radiotherapy. Clinical Cancer Research 11(17):6270-6279.
2. Bohl J, Combs SE, Debus J, Elsaesser T, Schulz-Ertner D, Weyrather WK. 2007 Jun. GSI scientific report 2006. Gesellschaft für Schwerionenforschung mbH; p 302.
3. Cordes N, Blaese MA, Meineke V, Van BD. 2002. Ionizing radiation induces up-regulation of functional beta1-integrin in human lung tumour cell lines in vitro. International Journal of Radiation Biology 78(5):347-357.
4. Cordes N, Hansmeier B, Beinke C, Meineke V, Van BD. 2003. Irradiation differentially affects substratum-dependent survival, adhesion, and invasion of glioblastoma cell lines. British Journal of Cancer 89(11):2122-2132.
5. Danen EH. 2005. Integrins: Regulators of tissue function and cancer progression. Current Pharmaceutical Design 11(7):881-891.
6. Friedl P, Wolf K. 2003. Tumour-cell invasion and migration: Diversity and escape mechanisms. Nature Reviews Cancer 3(5):362-374.
7. Giancotti FG, Ruoslahti E. 1999. Integrin signaling. Science 285(5430):1028-1032.
8. Goetze K, Mueller-Klieser W, Taucher-Scholz G, Scholz M. 2006 Aug. GSI scientific report 2005. Gesellschaft für Schwerionenforschung mbH; p 380.
9. Hood JD, Cheresh DA. 2002. Role of integrins in cell invasion and migration. Nature Reviews Cancer 2(2):91-100.
10. Kraft G. 1998. Radiotherapy with heavy ions: Radiobiology, clinical indications and experience at GSI, Darmstadt. Tumori 84(2):200-204.
11. Meineke V, Gilbertz KP, Schilperoort K, Cordes N, Sendler A, Moede T, Van BD. 2002. Ionizing radiation modulates cell surface integrin expression and adhesion of COLO-320 cells to collagen and fibronectin in vitro. Strahlentherapie und Onkologie 178(12):709-714.
12. Ogata T, Teshima T, Kagawa K, Hishikawa Y, Takahashi Y, Kawaguchi A, Suzumoto Y, Nojima K, Furusawa Y, Matsuura N. 2005. Particle irradiation suppresses metastatic potential of cancer cells. Cancer Research 65(1):113-120.
13. Rofstad EK, Mathiesen B, Galappathi K. 2004. Increased metastatic dissemination in human melanoma xenografts after subcurative radiation treatment: radiation-induced increase in fraction of hypoxic cells and hypoxia-induced up-regulation of urokinase-type plasminogen activator receptor. Cancer Research 64(1):13-18.
14. Schulz-Ertner D, Nikoghosyan A, Hof H, Didinger B, Combs SE, Jakel O, Karger CP, Edler L, Debus J. 2007. Carbon ion radiotherapy of skull base chondrosarcomas. International Journal of Radiation Oncology, Biology, Physics 67(1):171-177.
15. Schulz-Ertner D, Nikoghosyan A, Thilmann C, Haberer T, Jakel O, Karger C, Kraft G, Wannenmacher M, Debus J. 2004. Results of carbon ion radiotherapy in 152 patients. International Journal of Radiation Oncology, Biology, Physics 58(2):631-640.
16. Wedlich D. 2005. Cell migration in development and disease. Weinheim: Wiley-VCH Verlag GmbH & Co. KGaA.
17. Wild-Bode C, Weller M, Rimner A, Dichgans J, Wick W. 2001a. Sublethal irradiation promotes migration and invasiveness of glioma cells: Implications for radiotherapy of human glioblastoma. Cancer Research 61(6):2744-2750.
18. Wild-Bode C, Weller M, Wick W. 2001b. Molecular determinants of glioma cell migration and invasion. Journal of Neurosurgery 94(6):978-984.