-
1
-
-
0037844993
-
cDNA microarray analysis of gene expression in pathologic Stage IA nonsmall cell lung carcinomas
-
Nakamura H, Saji H, Ogata A et al. cDNA microarray analysis of gene expression in pathologic Stage IA nonsmall cell lung carcinomas. Cancer 2003; 97: 2798-2805
-
(2003)
Cancer
, vol.97
, pp. 2798-2805
-
-
Nakamura, H.1
Saji, H.2
Ogata, A.3
-
2
-
-
26644438582
-
Small-cell lung cancer
-
Jackman DM, Johnson BE. Small-cell lung cancer. Lancet 2005; 366: 1385-1396
-
(2005)
Lancet
, vol.366
, pp. 1385-1396
-
-
Jackman, D.M.1
Johnson, B.E.2
-
3
-
-
0035691670
-
The new World Health Organization classification of lung tumours
-
Brambilla E, Travis WD, Colby TV et al. The new World Health Organization classification of lung tumours. Eur Respir J 2001; 18: 1059-1068
-
(2001)
Eur Respir J
, vol.18
, pp. 1059-1068
-
-
Brambilla, E.1
Travis, W.D.2
Colby, T.V.3
-
4
-
-
3142683871
-
Gene expression-based, individualized outcome prediction for surgically treated lung cancer patients
-
Tomida S, Koshikawa K, Yatabe Y et al. Gene expression-based, individualized outcome prediction for surgically treated lung cancer patients. Oncogene 2004; 23: 5360-5370
-
(2004)
Oncogene
, vol.23
, pp. 5360-5370
-
-
Tomida, S.1
Koshikawa, K.2
Yatabe, Y.3
-
5
-
-
20544455590
-
Vinorelbine plus cisplatin vs. observation in resected non-small-cell lung cancer
-
Winton T, Livingston R, Johnson D et al. Vinorelbine plus cisplatin vs. observation in resected non-small-cell lung cancer. N Engl J Med 2005; 352: 2589-2597
-
(2005)
N Engl J Med
, vol.352
, pp. 2589-2597
-
-
Winton, T.1
Livingston, R.2
Johnson, D.3
-
6
-
-
33747847740
-
Adjuvant vinorelbine plus cisplatin versus observation in patients with completely resected stage IB-IIIA non-small-cell lung cancer (Adjuvant Navelbine International Trialist Association [ANITA]): A randomised controlled trial
-
Douillard JY, Rosell R, De Lena M et al. Adjuvant vinorelbine plus cisplatin versus observation in patients with completely resected stage IB-IIIA non-small-cell lung cancer (Adjuvant Navelbine International Trialist Association [ANITA]): a randomised controlled trial. Lancet Oncol 2006; 7: 719-727
-
(2006)
Lancet Oncol
, vol.7
, pp. 719-727
-
-
Douillard, J.Y.1
Rosell, R.2
De Lena, M.3
-
7
-
-
0346238665
-
Cisplatin-based adjuvant chemotherapy in patients with completely resected non-small-cell lung cancer
-
Arriagada R, Bergman B, Dunant A et al. Cisplatin-based adjuvant chemotherapy in patients with completely resected non-small-cell lung cancer. N Engl J Med 2004; 350: 351-360
-
(2004)
N Engl J Med
, vol.350
, pp. 351-360
-
-
Arriagada, R.1
Bergman, B.2
Dunant, A.3
-
8
-
-
0035868913
-
Twenty-two years of phase III trials for patients with advanced non-small-cell lung cancer: Sobering results
-
Breathnach OS, Freidlin B, Conley B et al. Twenty-two years of phase III trials for patients with advanced non-small-cell lung cancer: sobering results. J Clin Oncol 2001; 19: 1734-1742
-
(2001)
J Clin Oncol
, vol.19
, pp. 1734-1742
-
-
Breathnach, O.S.1
Freidlin, B.2
Conley, B.3
-
9
-
-
33744957443
-
Microarray analysis and tumor classification
-
Quackenbush J. Microarray analysis and tumor classification. N Engl J Med 2006; 354: 2463-2472
-
(2006)
N Engl J Med
, vol.354
, pp. 2463-2472
-
-
Quackenbush, J.1
-
10
-
-
3042788686
-
Tissue preparation for gene expression profiling of colorectal carcinoma: Three alternatives to laser microdissection with preamplification
-
Croner RS, Foertsch T, Siebenhaar R et al. Tissue preparation for gene expression profiling of colorectal carcinoma: Three alternatives to laser microdissection with preamplification. J Lab Clin Med 2004; 143: 344-351
-
(2004)
J Lab Clin Med
, vol.143
, pp. 344-351
-
-
Croner, R.S.1
Foertsch, T.2
Siebenhaar, R.3
-
12
-
-
18244409687
-
-
Veer LJ van't, Dai H, Vijver MJ van de et al. Gene expression profiling predicts clinical outcome of breast cancer. Nature 2002; 415: 530-536
-
Veer LJ van't, Dai H, Vijver MJ van de et al. Gene expression profiling predicts clinical outcome of breast cancer. Nature 2002; 415: 530-536
-
-
-
-
13
-
-
0037226593
-
A molecular signature of metastasis in primary solid tumors
-
Ramaswamy S, Ross KN, Lander ES et al. A molecular signature of metastasis in primary solid tumors. Nat Genet 2003; 33: 49-54
-
(2003)
Nat Genet
, vol.33
, pp. 49-54
-
-
Ramaswamy, S.1
Ross, K.N.2
Lander, E.S.3
-
14
-
-
0033569406
-
Molecular classification of cancer: Class discovery and class prediction by gene expression monitoring
-
Golub TR, Slonim DK, Tamayo P et al. Molecular classification of cancer: class discovery and class prediction by gene expression monitoring. Science 1999; 286: 531-537
-
(1999)
Science
, vol.286
, pp. 531-537
-
-
Golub, T.R.1
Slonim, D.K.2
Tamayo, P.3
-
15
-
-
21344470901
-
Common denominator genes that distinguish colorectal carcinoma from normal mucosa
-
Croner RS, Foertsch T, Brueckl WM et al. Common denominator genes that distinguish colorectal carcinoma from normal mucosa. Int J Colorectal Dis 2005; 20: 353-362
-
(2005)
Int J Colorectal Dis
, vol.20
, pp. 353-362
-
-
Croner, R.S.1
Foertsch, T.2
Brueckl, W.M.3
-
16
-
-
0034598746
-
Distinct types of diffuse large B-cell lymphoma identified by gene expression profiling
-
Alizadeh AA, Eisen MB, Davis RE et al. Distinct types of diffuse large B-cell lymphoma identified by gene expression profiling. Nature 2000; 403: 503-511
-
(2000)
Nature
, vol.403
, pp. 503-511
-
-
Alizadeh, A.A.1
Eisen, M.B.2
Davis, R.E.3
-
17
-
-
33746875641
-
A genomic strategy to refine prognosis in early-stage non-small-cell lung cancer
-
Potti A, Mukherjee S, Petersen R et al. A genomic strategy to refine prognosis in early-stage non-small-cell lung cancer. N Engl J Med 2006; 355: 570-580
-
(2006)
N Engl J Med
, vol.355
, pp. 570-580
-
-
Potti, A.1
Mukherjee, S.2
Petersen, R.3
-
18
-
-
0035349035
-
Criteria for evaluating prognostic factors
-
Hermanek P, Mansmann U. Criteria for evaluating prognostic factors. Chirurg 2001; 72: 474-480
-
(2001)
Chirurg
, vol.72
, pp. 474-480
-
-
Hermanek, P.1
Mansmann, U.2
-
19
-
-
0032412988
-
Assessing the clinical impact of prognostic factors: When is "statistically significant" clinically useful?
-
Hayes DF, Trock B, Harris AL. Assessing the clinical impact of prognostic factors: when is "statistically significant" clinically useful? Breast Cancer Res Treat 1998; 52: 305-319
-
(1998)
Breast Cancer Res Treat
, vol.52
, pp. 305-319
-
-
Hayes, D.F.1
Trock, B.2
Harris, A.L.3
-
20
-
-
33744909361
-
From description to causality: Mechanisms of gene expression signatures in cancer
-
Adler AS, Chang HY. From description to causality: mechanisms of gene expression signatures in cancer. Cell Cycle 2006; 5: 1148-1151
-
(2006)
Cell Cycle
, vol.5
, pp. 1148-1151
-
-
Adler, A.S.1
Chang, H.Y.2
-
22
-
-
0035909987
-
Molecular characteristics of non-small cell lung cancer
-
Nacht M, Dracheva T, Gao Y et al. Molecular characteristics of non-small cell lung cancer. Proc Natl Acad Sci U S A 2001; 98: 15 203-15 208
-
(2001)
Proc Natl Acad Sci U S A
, vol.98
-
-
Nacht, M.1
Dracheva, T.2
Gao, Y.3
-
23
-
-
0037126055
-
Integrated classification of lung tumors and cell lines by expression profiling
-
Virtanen C, Ishikawa Y, Honjoh D et al. Integrated classification of lung tumors and cell lines by expression profiling. Proc Natl Acad Sci U S A 2002; 99: 12 357-12 362
-
(2002)
Proc Natl Acad Sci U S A
, vol.99
-
-
Virtanen, C.1
Ishikawa, Y.2
Honjoh, D.3
-
24
-
-
0142151074
-
Non-small-cell lung cancer molecular signatures recapitulate lung developmental pathways
-
Borczuk AC, Gorenstein L, Walter KL et al. Non-small-cell lung cancer molecular signatures recapitulate lung developmental pathways. Am J Pathol 2003; 163: 1949-1960
-
(2003)
Am J Pathol
, vol.163
, pp. 1949-1960
-
-
Borczuk, A.C.1
Gorenstein, L.2
Walter, K.L.3
-
25
-
-
22044453790
-
Erlotinib in lung cancer - molecular and clinical predictors of outcome
-
Tsao MS, Sakurada A, Cutz JC et al. Erlotinib in lung cancer - molecular and clinical predictors of outcome. N Engl J Med 2005; 353: 133-144
-
(2005)
N Engl J Med
, vol.353
, pp. 133-144
-
-
Tsao, M.S.1
Sakurada, A.2
Cutz, J.C.3
-
26
-
-
34447130180
-
FDA drug approval summary: Bevacizumab (Avastin) plus Carboplatin and Paclitaxel as first-line treatment of advanced/metastatic recurrent nonsquamous non-small cell lung cancer
-
Cohen MH, Gootenberg J, Keegan P et al. FDA drug approval summary: bevacizumab (Avastin) plus Carboplatin and Paclitaxel as first-line treatment of advanced/metastatic recurrent nonsquamous non-small cell lung cancer. Oncologist 2007; 12: 713-718
-
(2007)
Oncologist
, vol.12
, pp. 713-718
-
-
Cohen, M.H.1
Gootenberg, J.2
Keegan, P.3
-
27
-
-
33845490014
-
Paclitaxel-carboplatin alone or with bevacizumab for non-small-cell lung cancer
-
Sandler A, Gray R, Perry MC et al. Paclitaxel-carboplatin alone or with bevacizumab for non-small-cell lung cancer. N Engl J Med 2006; 355: 2542-2550
-
(2006)
N Engl J Med
, vol.355
, pp. 2542-2550
-
-
Sandler, A.1
Gray, R.2
Perry, M.C.3
-
28
-
-
33750144030
-
Advanced non-small-cell lung cancer: New data, therapy choices, and challenging decisions
-
Sandler AB. Advanced non-small-cell lung cancer: new data, therapy choices, and challenging decisions. Oncology 2006; 20: 626-628
-
(2006)
Oncology
, vol.20
, pp. 626-628
-
-
AB, S.1
-
29
-
-
2942657615
-
Randomized phase II trial comparing bevacizumab plus carboplatin and paclitaxel with carboplatin and paclitaxel alone in previously untreated locally advanced or metastatic non-small-cell lung cancer
-
Johnson DH, Fehrenbacher L, Novotny WF et al. Randomized phase II trial comparing bevacizumab plus carboplatin and paclitaxel with carboplatin and paclitaxel alone in previously untreated locally advanced or metastatic non-small-cell lung cancer. J Clin Oncol 2004; 22: 2184-2191
-
(2004)
J Clin Oncol
, vol.22
, pp. 2184-2191
-
-
Johnson, D.H.1
Fehrenbacher, L.2
Novotny, W.F.3
-
30
-
-
0030912190
-
Revisions in the International System for Staging Lung Cancer
-
Mountain CF. Revisions in the International System for Staging Lung Cancer. Chest 1997; 111: 1710-1717
-
(1997)
Chest
, vol.111
, pp. 1710-1717
-
-
CF, M.1
-
31
-
-
0031892132
-
Functional evaluation of the lung resection candidate
-
Bolliger CT, Perruchoud AP. Functional evaluation of the lung resection candidate. Eur Respir J 1998; 11: 198-212
-
(1998)
Eur Respir J
, vol.11
, pp. 198-212
-
-
Bolliger, C.T.1
Perruchoud, A.P.2
-
32
-
-
33846011470
-
A five-gene signature and clinical outcome in non-small-cell lung cancer
-
Chen HY, Yu SL, Chen CH et al. A five-gene signature and clinical outcome in non-small-cell lung cancer. N Engl J Med 2007; 356: 11-20
-
(2007)
N Engl J Med
, vol.356
, pp. 11-20
-
-
Chen, H.Y.1
Yu, S.L.2
Chen, C.H.3
-
33
-
-
34249704163
-
Referral patterns for adjuvant chemotherapy in patients with completely resected non-small cell lung cancer
-
Kassam F, Shepherd FA, Johnston M et al. Referral patterns for adjuvant chemotherapy in patients with completely resected non-small cell lung cancer. J Thorac Oncol 2007; 2: 39-43
-
(2007)
J Thorac Oncol
, vol.2
, pp. 39-43
-
-
Kassam, F.1
Shepherd, F.A.2
Johnston, M.3
-
34
-
-
33747820148
-
Lung Adjuvant Cisplatin Evaluation (LACE): A pooled analysis of five randomized clicial trials including 4,584 patients
-
366s
-
Pignon JP, Tribodet H, Scagliotti GV et al. Lung Adjuvant Cisplatin Evaluation (LACE): a pooled analysis of five randomized clicial trials including 4,584 patients. Proc Am Soc Clin Oncol 2006; 24: 366s
-
(2006)
Proc Am Soc Clin Oncol
, vol.24
-
-
Pignon, J.P.1
Tribodet, H.2
Scagliotti, G.V.3
-
35
-
-
34147158870
-
Optimal adjuvant therapy for non-small cell lung cancer - how to handle stage I disease
-
Wakelee H, Dubey S, Gandara D. Optimal adjuvant therapy for non-small cell lung cancer - how to handle stage I disease. Oncologist 2007; 12: 331-337
-
(2007)
Oncologist
, vol.12
, pp. 331-337
-
-
Wakelee, H.1
Dubey, S.2
Gandara, D.3
-
36
-
-
0027949292
-
A placebo-controlled randomized double-blind study of adjuvant intrapleural BCG in patients with resected T1N0, T1N1, or T2N0 squamous cell carcinoma, adenocarcinoma, or large cell carcinoma of the lung. LCSG Protocol 771
-
Gail MH. A placebo-controlled randomized double-blind study of adjuvant intrapleural BCG in patients with resected T1N0, T1N1, or T2N0 squamous cell carcinoma, adenocarcinoma, or large cell carcinoma of the lung. LCSG Protocol 771. Chest 1994; 106: 287S-292S
-
(1994)
Chest
, vol.106
-
-
MH, G.1
-
37
-
-
17144449993
-
Surgery in locally advanced non-small cell lung cancer
-
Naruke T. Surgery in locally advanced non-small cell lung cancer. Lung Cancer 2003; 42 Suppl 2: S11-15
-
(2003)
Lung Cancer
, vol.42
, Issue.SUPPL. 2
-
-
Naruke, T.1
-
38
-
-
33748487809
-
Pharmacologic treatment of bronchial cancer. Part 1: Standards
-
Serke M. Pharmacologic treatment of bronchial cancer. Part 1: Standards. Pneumologie 2006; 60: 493-508
-
(2006)
Pneumologie
, vol.60
, pp. 493-508
-
-
Serke, M.1
-
39
-
-
33845494722
-
-
Cecere F, Bria E, Resell R. DNA repair by ERCC1 in non-small-cell lung cancer. N Engl J Med 2006; 355: 2590-2591 author reply 2591
-
Cecere F, Bria E, Resell R. DNA repair by ERCC1 in non-small-cell lung cancer. N Engl J Med 2006; 355: 2590-2591 author reply 2591
-
-
-
-
40
-
-
33845472882
-
DNA repair by ERCC1 in non-small-cell lung cancer
-
Grenader T, Shavit L. DNA repair by ERCC1 in non-small-cell lung cancer. N Engl J Med 2006; 355: 2591
-
(2006)
N Engl J Med
, vol.355
, pp. 2591
-
-
Grenader, T.1
Shavit, L.2
-
41
-
-
24344456401
-
ERCC1 and clinical resistance to platinum-based therapy
-
Reed E. ERCC1 and clinical resistance to platinum-based therapy. Clin Cancer Res 2005; 11: 6100-6102
-
(2005)
Clin Cancer Res
, vol.11
, pp. 6100-6102
-
-
Reed, E.1
-
42
-
-
0031982522
-
ERCC1 mRNA levels complement thymidylate synthase mRNA levels in predicting response and survival for gastric cancer patients receiving combination cisplatin and fluorouracil chemotherapy
-
Metzger R, Leichman CG, Danenberg KD et al. ERCC1 mRNA levels complement thymidylate synthase mRNA levels in predicting response and survival for gastric cancer patients receiving combination cisplatin and fluorouracil chemotherapy. J Clin Oncol 1998; 16: 309-316
-
(1998)
J Clin Oncol
, vol.16
, pp. 309-316
-
-
Metzger, R.1
Leichman, C.G.2
Danenberg, K.D.3
-
43
-
-
0028141961
-
Messenger RNA levels of XPAC and ERCC1 in ovarian cancer tissue correlate with response to platinum-based chemotherapy
-
Dabholkar M, Vionnet J, Bostick-Bruton F et al. Messenger RNA levels of XPAC and ERCC1 in ovarian cancer tissue correlate with response to platinum-based chemotherapy. J Clin Invest 1994; 94: 703-708
-
(1994)
J Clin Invest
, vol.94
, pp. 703-708
-
-
Dabholkar, M.1
Vionnet, J.2
Bostick-Bruton, F.3
-
44
-
-
0035988959
-
Low ERCC1 expression correlates with prolonged survival after cisplatin plus gemcitabine chemotherapy in non-small cell lung cancer
-
Lord RV, Brabender J, Gandara D et al. Low ERCC1 expression correlates with prolonged survival after cisplatin plus gemcitabine chemotherapy in non-small cell lung cancer. Clin Cancer Res 2002; 8: 2286-2291
-
(2002)
Clin Cancer Res
, vol.8
, pp. 2286-2291
-
-
Lord, R.V.1
Brabender, J.2
Gandara, D.3
-
45
-
-
33748435058
-
DNA repair by ERCC1 in non-small-cell lung cancer and cisplatin-based adjuvant chemotherapy
-
Olaussen KA, Dunant A, Fouret P et al. DNA repair by ERCC1 in non-small-cell lung cancer and cisplatin-based adjuvant chemotherapy. N Engl J Med 2006; 355: 983-991
-
(2006)
N Engl J Med
, vol.355
, pp. 983-991
-
-
Olaussen, K.A.1
Dunant, A.2
Fouret, P.3
-
46
-
-
34249819963
-
-
Olaussen KA, Mountzios G, Soria JC. ERCC1 as a risk stratifier in platinum-based chemotherapy for nonsmall-cell lung cancer. Curr Opin Pulm Med 2007; 13: 284-289
-
Olaussen KA, Mountzios G, Soria JC. ERCC1 as a risk stratifier in platinum-based chemotherapy for nonsmall-cell lung cancer. Curr Opin Pulm Med 2007; 13: 284-289
-
-
-
-
47
-
-
33847107236
-
DNA synthesis and repair genes RRM1 and ERCC1 in lung cancer
-
Zheng Z, Chen T, Li X et al. DNA synthesis and repair genes RRM1 and ERCC1 in lung cancer. N Engl J Med 2007; 356: 800-808
-
(2007)
N Engl J Med
, vol.356
, pp. 800-808
-
-
Zheng, Z.1
Chen, T.2
Li, X.3
-
48
-
-
27744446615
-
Using translational research to tailor the use of chemotherapy in the treatment of NSCLC
-
Bepler G. Using translational research to tailor the use of chemotherapy in the treatment of NSCLC. Lung Cancer 2005; 50 Suppl 1: S13-34
-
(2005)
Lung Cancer
, vol.50
, Issue.SUPPL. 1
-
-
Bepler, G.1
-
49
-
-
21044445279
-
Mutation in the tyrosine kinase domain of epidermal growth factor receptor is a predictive and prognostic factor for gefitinib treatment in patients with non-small cell lung cancer
-
Chou TY, Chiu CH, Li LH et al. Mutation in the tyrosine kinase domain of epidermal growth factor receptor is a predictive and prognostic factor for gefitinib treatment in patients with non-small cell lung cancer. Clin Cancer Res 2005; 11: 3750-3757
-
(2005)
Clin Cancer Res
, vol.11
, pp. 3750-3757
-
-
Chou, T.Y.1
Chiu, C.H.2
Li, L.H.3
-
50
-
-
0028843552
-
Chemotherapy in non-small cell lung cancer: A meta-analysis using updated data on individual patients from 52 randomised clinical trials
-
Non-small Cell Lung Cancer Collaborative Group
-
Non-small Cell Lung Cancer Collaborative Group. Chemotherapy in non-small cell lung cancer: a meta-analysis using updated data on individual patients from 52 randomised clinical trials. Bmj 1995; 311: 899-909
-
(1995)
Bmj
, vol.311
, pp. 899-909
-
-
-
51
-
-
33745152761
-
Lung cancer
-
quiz 621
-
Huber RM. Lung cancer. Internist 2006; 47: 611-620 quiz 621
-
(2006)
Internist
, vol.47
, pp. 611-620
-
-
RM, H.1
-
52
-
-
1242318822
-
State-of-the-art chemotherapy for advanced non-small cell lung cancer
-
Ramalingam S, Belani CP. State-of-the-art chemotherapy for advanced non-small cell lung cancer. Semin Oncol 2004; 31: 68-74
-
(2004)
Semin Oncol
, vol.31
, pp. 68-74
-
-
Ramalingam, S.1
Belani, C.P.2
-
53
-
-
0034069620
-
Prospective randomized trial of docetaxel versus best supportive care in patients with non-small-cell lung cancer previously treated with platinum-based chemotherapy
-
Shepherd FA, Dancey J, Ramlau R et al. Prospective randomized trial of docetaxel versus best supportive care in patients with non-small-cell lung cancer previously treated with platinum-based chemotherapy. J Clin Oncol 2000; 18: 2095-2103
-
(2000)
J Clin Oncol
, vol.18
, pp. 2095-2103
-
-
Shepherd, F.A.1
Dancey, J.2
Ramlau, R.3
-
54
-
-
22044445517
-
Erlotinib in previously treated non-small-cell lung cancer
-
Shepherd FA, Rodrigues PereiraJ, Ciuleanu T et al. Erlotinib in previously treated non-small-cell lung cancer. N Engl J Med 2005; 353: 123-132
-
(2005)
N Engl J Med
, vol.353
, pp. 123-132
-
-
Shepherd, F.A.1
PereiraJ, R.2
Ciuleanu, T.3
-
55
-
-
2442661845
-
Randomized phase III trial of pemetrexed versus docetaxel in patients with non-small-cell lung cancer previously treated with chemotherapy
-
Hanna N, Shepherd FA, Fossella FV et al. Randomized phase III trial of pemetrexed versus docetaxel in patients with non-small-cell lung cancer previously treated with chemotherapy. J Clin Oncol 2004; 22: 1589-1597
-
(2004)
J Clin Oncol
, vol.22
, pp. 1589-1597
-
-
Hanna, N.1
Shepherd, F.A.2
Fossella, F.V.3
-
56
-
-
0037838557
-
Development of the epidermal growth factor receptor inhibitor OSI-774
-
Grunwald V, Hidalgo M. Development of the epidermal growth factor receptor inhibitor OSI-774. Semin Oncol 2003; 30: 23-31
-
(2003)
Semin Oncol
, vol.30
, pp. 23-31
-
-
Grunwald, V.1
Hidalgo, M.2
-
57
-
-
0030774045
-
Induction of apoptosis and cell cycle arrest by CP-358,774, an inhibitor of epidermal growth factor receptor tyrosine kinase
-
Moyer JD, Barbacci EG, Iwata KK et al. Induction of apoptosis and cell cycle arrest by CP-358,774, an inhibitor of epidermal growth factor receptor tyrosine kinase. Cancer Res 1997; 57: 4838-4848
-
(1997)
Cancer Res
, vol.57
, pp. 4838-4848
-
-
Moyer, J.D.1
Barbacci, E.G.2
Iwata, K.K.3
-
58
-
-
0032695910
-
Inhibition of epidermal growth factor receptor-associated tyrosine phosphorylation in human carcinomas with CP-358,774: Dynamics of receptor inhibition in situ and antitumor effects in athymic mice
-
Pollack VA, Savage DM, Baker DA et al. Inhibition of epidermal growth factor receptor-associated tyrosine phosphorylation in human carcinomas with CP-358,774: dynamics of receptor inhibition in situ and antitumor effects in athymic mice. J Pharmacol Exp Ther 1999; 291: 739-748
-
(1999)
J Pharmacol Exp Ther
, vol.291
, pp. 739-748
-
-
Pollack, V.A.1
Savage, D.M.2
Baker, D.A.3
-
60
-
-
0023187984
-
Molecular evidence for the lack of epidermal growth factor receptor gene expression in small cell lung carcinoma cells
-
Gamou S, Hunts J, Harigai H et al. Molecular evidence for the lack of epidermal growth factor receptor gene expression in small cell lung carcinoma cells. Cancer Res 1987; 47: 2668-2673
-
(1987)
Cancer Res
, vol.47
, pp. 2668-2673
-
-
Gamou, S.1
Hunts, J.2
Harigai, H.3
-
61
-
-
20044364940
-
Clinical and biological features associated with epidermal growth factor receptor gene mutations in lung cancers
-
Shigematsu H, Lin L, Takahashi T et al. Clinical and biological features associated with epidermal growth factor receptor gene mutations in lung cancers. J Natl Cancer Inst 2005; 97: 339-346
-
(2005)
J Natl Cancer Inst
, vol.97
, pp. 339-346
-
-
Shigematsu, H.1
Lin, L.2
Takahashi, T.3
-
62
-
-
4143051317
-
Excision repair cross-complementation group 1 polymorphism predicts overall survival in advanced non-small cell lung cancer patients treated with platinum-based chemotherapy
-
Zhou W, Gurubhagavatula S, Liu G et al. Excision repair cross-complementation group 1 polymorphism predicts overall survival in advanced non-small cell lung cancer patients treated with platinum-based chemotherapy. Clin Cancer Res 2004; 10: 4939-4943
-
(2004)
Clin Cancer Res
, vol.10
, pp. 4939-4943
-
-
Zhou, W.1
Gurubhagavatula, S.2
Liu, G.3
-
63
-
-
20044364933
-
EGFR mutations in non-small-cell lung cancer: Analysis of a large series of cases and development of a rapid and sensitive method for diagnostic screening with potential implications on pharmacologic treatment
-
Marchetti A, Martella C, Felicioni L et al. EGFR mutations in non-small-cell lung cancer: analysis of a large series of cases and development of a rapid and sensitive method for diagnostic screening with potential implications on pharmacologic treatment. J Clin Oncol 2005; 23: 857-865
-
(2005)
J Clin Oncol
, vol.23
, pp. 857-865
-
-
Marchetti, A.1
Martella, C.2
Felicioni, L.3
-
64
-
-
20244388126
-
Mutations of the epidermal growth factor receptor gene predict prolonged survival after gefitinib treatment in patients with non-small-cell lung cancer with postoperative recurrence
-
Mitsudomi T, Kosaka T, Endoh H et al. Mutations of the epidermal growth factor receptor gene predict prolonged survival after gefitinib treatment in patients with non-small-cell lung cancer with postoperative recurrence. J Clin Oncol 2005; 23: 2513-2520
-
(2005)
J Clin Oncol
, vol.23
, pp. 2513-2520
-
-
Mitsudomi, T.1
Kosaka, T.2
Endoh, H.3
-
65
-
-
10844231985
-
Mutations of the epidermal growth factor receptor gene in lung cancer: Biological and clinical implications
-
Kosaka T, Yatabe Y, Endoh H et al. Mutations of the epidermal growth factor receptor gene in lung cancer: biological and clinical implications. Cancer Res 2004; 64: 8919-8923
-
(2004)
Cancer Res
, vol.64
, pp. 8919-8923
-
-
Kosaka, T.1
Yatabe, Y.2
Endoh, H.3
-
66
-
-
33746034167
-
Exon 19 deletion mutations of epidermal growth factor receptor are associated with prolonged survival in non-small cell lung cancer patients treated with gefitinib or erlotinib
-
Jackman DM, Yeap BY, Sequist LV et al. Exon 19 deletion mutations of epidermal growth factor receptor are associated with prolonged survival in non-small cell lung cancer patients treated with gefitinib or erlotinib. Clin Cancer Res 2006; 12: 3908-3914
-
(2006)
Clin Cancer Res
, vol.12
, pp. 3908-3914
-
-
Jackman, D.M.1
Yeap, B.Y.2
Sequist, L.V.3
-
67
-
-
27744499056
-
Combining EGFR targeted therapy with chemotherapy in pancreatic cancer: Is timing important?
-
Riely GJ, Pao W. Combining EGFR targeted therapy with chemotherapy in pancreatic cancer: is timing important? Cancer Biol Ther 2005; 4: 1096-1097
-
(2005)
Cancer Biol Ther
, vol.4
, pp. 1096-1097
-
-
Riely, G.J.1
Pao, W.2
-
68
-
-
20444498630
-
Epidermal growth factor receptor gene and protein and gefitinib sensitivity in non-small-cell lung cancer
-
Cappuzzo F, Hirsch FR, Rossi E et al. Epidermal growth factor receptor gene and protein and gefitinib sensitivity in non-small-cell lung cancer. J Natl Cancer Inst 2005; 97: 643-655
-
(2005)
J Natl Cancer Inst
, vol.97
, pp. 643-655
-
-
Cappuzzo, F.1
Hirsch, F.R.2
Rossi, E.3
-
69
-
-
20244389188
-
Predictive and prognostic impact of epidermal growth factor receptor mutation in non-small-cell lung cancer patients treated with gefitinib
-
Han SW, Kim TY, Hwang PG et al. Predictive and prognostic impact of epidermal growth factor receptor mutation in non-small-cell lung cancer patients treated with gefitinib. J Clin Oncol 2005; 23: 2493-2501
-
(2005)
J Clin Oncol
, vol.23
, pp. 2493-2501
-
-
Han, S.W.1
Kim, T.Y.2
Hwang, P.G.3
-
70
-
-
27244451321
-
Epidermal growth factor receptor gene mutations and increased copy numbers predict gefitinib sensitivity in patients with recurrent non-small-cell lung cancer
-
Takano T, Ohe Y, Sakamoto H et al. Epidermal growth factor receptor gene mutations and increased copy numbers predict gefitinib sensitivity in patients with recurrent non-small-cell lung cancer. J Clin Oncol 2005; 23: 6829-6837
-
(2005)
J Clin Oncol
, vol.23
, pp. 6829-6837
-
-
Takano, T.1
Ohe, Y.2
Sakamoto, H.3
-
71
-
-
23844490782
-
Activating mutations in the tyrosine kinase domain of the epidermal growth factor receptor are associated with improved survival in gefitinib-treated chemorefractory lung adenocarcinomas
-
Taron M, Ichinose Y, Resell R et al. Activating mutations in the tyrosine kinase domain of the epidermal growth factor receptor are associated with improved survival in gefitinib-treated chemorefractory lung adenocarcinomas. Clin Cancer Res 2005; 11: 5878-5885
-
(2005)
Clin Cancer Res
, vol.11
, pp. 5878-5885
-
-
Taron, M.1
Ichinose, Y.2
Resell, R.3
-
72
-
-
23844517762
-
The EGFR mutation and its correlation with response of gefitinib in previously treated Chinese patients with advanced non-small-cell lung cancer
-
Zhang XT, Li LY, Mu XL et al. The EGFR mutation and its correlation with response of gefitinib in previously treated Chinese patients with advanced non-small-cell lung cancer. Ann Oncol 2005; 16: 1334-1342
-
(2005)
Ann Oncol
, vol.16
, pp. 1334-1342
-
-
Zhang, X.T.1
Li, L.Y.2
Mu, X.L.3
-
73
-
-
28844461559
-
Common EGFR mutations conferring sensitivity to gefitinib in lung adenocarcinoma are not prevalent in human malignant mesothelioma
-
Cortese JF, Gowda AL, Wali A et al. Common EGFR mutations conferring sensitivity to gefitinib in lung adenocarcinoma are not prevalent in human malignant mesothelioma. Int J Cancer 2006; 118: 521-522
-
(2006)
Int J Cancer
, vol.118
, pp. 521-522
-
-
Cortese, J.F.1
Gowda, A.L.2
Wali, A.3
-
74
-
-
33750205340
-
A phase II trial of gefitinib as first-line therapy for advanced non-small cell lung cancer with epidermal growth factor receptor mutations
-
Asahina H, Yamazaki K, Kinoshita I et al. A phase II trial of gefitinib as first-line therapy for advanced non-small cell lung cancer with epidermal growth factor receptor mutations. Br J Cancer 2006; 95: 998-1004
-
(2006)
Br J Cancer
, vol.95
, pp. 998-1004
-
-
Asahina, H.1
Yamazaki, K.2
Kinoshita, I.3
-
75
-
-
34347368906
-
Setting the benchmark for tailoring treatment with EGFR tyrosine kinase inhibitors
-
Rosell R, Taron M, Sanchez JJ et al. Setting the benchmark for tailoring treatment with EGFR tyrosine kinase inhibitors. Future Oncol 2007; 3: 277-283
-
(2007)
Future Oncol
, vol.3
, pp. 277-283
-
-
Rosell, R.1
Taron, M.2
Sanchez, J.J.3
-
76
-
-
33746789922
-
Prospective phase II study of gefitinib for chemotherapy-naive patients with advanced non-small-cell lung cancer with epidermal growth factor receptor gene mutations
-
Inoue A, Suzuki T, Fukuhara T et al. Prospective phase II study of gefitinib for chemotherapy-naive patients with advanced non-small-cell lung cancer with epidermal growth factor receptor gene mutations. J Clin Oncol 2006; 24: 3340-3346
-
(2006)
J Clin Oncol
, vol.24
, pp. 3340-3346
-
-
Inoue, A.1
Suzuki, T.2
Fukuhara, T.3
-
77
-
-
33845434121
-
A prospective phase II trial of erlotinib in advanced non-small cell lung cancer patients with mutations in the tyrosine kinase domain of the EGF-R
-
Paz-Ares L, Sanchez IM, Garcia-Velasco A et al. A prospective phase II trial of erlotinib in advanced non-small cell lung cancer patients with mutations in the tyrosine kinase domain of the EGF-R Proc. ASCO 2006; 24: 7020
-
(2006)
Proc. ASCO
, vol.24
, pp. 7020
-
-
Paz-Ares, L.1
Sanchez, I.M.2
Garcia-Velasco, A.3
-
78
-
-
33947498978
-
Molecular predictors of response to epidermal growth factor receptor antagonists in non-small-cell lung cancer
-
Sequist LV, Bell DW, Lynch TJ et al. Molecular predictors of response to epidermal growth factor receptor antagonists in non-small-cell lung cancer. J Clin Oncol 2007; 25: 587-595
-
(2007)
J Clin Oncol
, vol.25
, pp. 587-595
-
-
Sequist, L.V.1
Bell, D.W.2
Lynch, T.J.3
-
79
-
-
13844317894
-
EGFR mutation and resistance of non-small-cell lung cancer to gefitinib
-
Kobayashi S, Boggon TJ, Dayaram T et al. EGFR mutation and resistance of non-small-cell lung cancer to gefitinib. N Engl J Med 2005; 352: 786-792
-
(2005)
N Engl J Med
, vol.352
, pp. 786-792
-
-
Kobayashi, S.1
Boggon, T.J.2
Dayaram, T.3
-
80
-
-
18244371651
-
Acquired resistance of lung adenocarcinomas to gefitinib or erlotinib is associated with a second mutation in the EGFR kinase domain
-
Pao W, Miller VA, Politi KA et al. Acquired resistance of lung adenocarcinomas to gefitinib or erlotinib is associated with a second mutation in the EGFR kinase domain. PLoS Med 2005; 2: e73
-
(2005)
PLoS Med
, vol.2
-
-
Pao, W.1
Miller, V.A.2
Politi, K.A.3
-
81
-
-
21144439000
-
Irreversible inhibitors of the EGF receptor may circumvent acquired resistance to gefitinib
-
Kwak EL, Sordella R, Bell DW et al. Irreversible inhibitors of the EGF receptor may circumvent acquired resistance to gefitinib. Proc Natl Acad Sci U S A 2005; 102: 7665-7670
-
(2005)
Proc Natl Acad Sci U S A
, vol.102
, pp. 7665-7670
-
-
Kwak, E.L.1
Sordella, R.2
Bell, D.W.3
-
82
-
-
33646418681
-
Optimization of patient selection for gefitinib in non-small cell lung cancer by combined analysis of epidermal growth factor receptor mutation, K-ras mutation, and Akt phosphorylation
-
Han SW, Kim TY, Jeon YK et al. Optimization of patient selection for gefitinib in non-small cell lung cancer by combined analysis of epidermal growth factor receptor mutation, K-ras mutation, and Akt phosphorylation. Clin Cancer Res 2006; 12: 2538-2544
-
(2006)
Clin Cancer Res
, vol.12
, pp. 2538-2544
-
-
Han, S.W.1
Kim, T.Y.2
Jeon, Y.K.3
-
83
-
-
15744372810
-
KRAS mutations and primary resistance of lung adenocarcinomas to gefitinib or erlotinib
-
Pao W, Wang TY, Riely GJ et al. KRAS mutations and primary resistance of lung adenocarcinomas to gefitinib or erlotinib. PLoS Med 2005; 2: e17
-
(2005)
PLoS Med
, vol.2
-
-
Pao, W.1
Wang, T.Y.2
Riely, G.J.3
-
84
-
-
24944497744
-
Mutations in the epidermal growth factor receptor and in KRAS are predictive and prognostic indicators in patients with non-small-cell lung cancer treated with chemotherapy alone and in combination with erlotinib
-
Eberhard DA, Johnson BE, Amler LC et al. Mutations in the epidermal growth factor receptor and in KRAS are predictive and prognostic indicators in patients with non-small-cell lung cancer treated with chemotherapy alone and in combination with erlotinib. J Clin Oncol 2005; 23: 5900-5909
-
(2005)
J Clin Oncol
, vol.23
, pp. 5900-5909
-
-
Eberhard, D.A.1
Johnson, B.E.2
Amler, L.C.3
-
85
-
-
33644822965
-
Epidermal growth factor receptor inhibitors in lung cancer: Smaller or larger molecules, selected or unselected populations?
-
Hirsch FR, Bunn JrPA. Epidermal growth factor receptor inhibitors in lung cancer: smaller or larger molecules, selected or unselected populations? J Clin Oncol 2005; 23: 9044-9047
-
(2005)
J Clin Oncol
, vol.23
, pp. 9044-9047
-
-
Hirsch, F.R.1
JrPA, B.2
-
86
-
-
28844449401
-
Epidermal growth factor receptor mutations and gene amplification in non-small-cell lung cancer: Molecular analysis of the IDEAL/INTACT gefitinib trials
-
Bell DW, Lynch TJ, Haserlat SM et al. Epidermal growth factor receptor mutations and gene amplification in non-small-cell lung cancer: molecular analysis of the IDEAL/INTACT gefitinib trials. J Clin Oncol 2005; 23: 8081-8092
-
(2005)
J Clin Oncol
, vol.23
, pp. 8081-8092
-
-
Bell, D.W.1
Lynch, T.J.2
Haserlat, S.M.3
-
87
-
-
23844491524
-
Differential effects of gefitinib and cetuximab on non-small-cell lung cancers bearing epidermal growth factor receptor mutations
-
Mukohara T, Engelman JA, Hanna NH et al. Differential effects of gefitinib and cetuximab on non-small-cell lung cancers bearing epidermal growth factor receptor mutations. J Natl Cancer Inst 2005; 97: 1185-1194
-
(2005)
J Natl Cancer Inst
, vol.97
, pp. 1185-1194
-
-
Mukohara, T.1
Engelman, J.A.2
Hanna, N.H.3
-
88
-
-
33947415279
-
Phase II trial of cetuximab inpatients with previously treated non-small-cell lung cancer
-
Hanna N, Lilenbaum R, Ansari R et al. Phase II trial of cetuximab inpatients with previously treated non-small-cell lung cancer. J Clin Oncol 2006; 24: 5253-5258
-
(2006)
J Clin Oncol
, vol.24
, pp. 5253-5258
-
-
Hanna, N.1
Lilenbaum, R.2
Ansari, R.3
-
89
-
-
0038418869
-
Chk1 and Chk2 kinases in checkpoint control and cancer
-
Bartek J, Lukas J. Chk1 and Chk2 kinases in checkpoint control and cancer. Cancer Cell 2003; 3: 421-429
-
(2003)
Cancer Cell
, vol.3
, pp. 421-429
-
-
Bartek, J.1
Lukas, J.2
-
90
-
-
0036510055
-
The DNA damage-dependent intra-S phase checkpoint is regulated by parallel pathways
-
Falck J, Petrini JH, Williams BR et al. The DNA damage-dependent intra-S phase checkpoint is regulated by parallel pathways. Nat Genet 2002; 30: 290-394
-
(2002)
Nat Genet
, vol.30
, pp. 290-394
-
-
Falck, J.1
Petrini, J.H.2
Williams, B.R.3
-
91
-
-
33750339641
-
Non-Small Cell Lung Cancers with Kinase Domain Mutations in the Epidermal Growth Factor Receptor Are Sensitive to Ionizing Radiation
-
Das AK, Sato M, Story MD et al. Non-Small Cell Lung Cancers with Kinase Domain Mutations in the Epidermal Growth Factor Receptor Are Sensitive to Ionizing Radiation. Cancer Res 2006; 66: 9601-9608
-
(2006)
Cancer Res
, vol.66
, pp. 9601-9608
-
-
Das, A.K.1
Sato, M.2
Story, M.D.3
-
92
-
-
19944427144
-
The effects of cetuximab alone and in combination with radiation and/or chemotherapy in lung cancer
-
Raben D, Helfrich B, Chan DC et al. The effects of cetuximab alone and in combination with radiation and/or chemotherapy in lung cancer. Clin Cancer Res 2005; 11: 795-805
-
(2005)
Clin Cancer Res
, vol.11
, pp. 795-805
-
-
Raben, D.1
Helfrich, B.2
Chan, D.C.3
-
93
-
-
32144433159
-
Radiotherapy plus cetuximab for squamous-cell carcinoma of the head and neck
-
Bonner JA, Harari PM, Giralt J et al. Radiotherapy plus cetuximab for squamous-cell carcinoma of the head and neck. N Engl J Med 2006; 354: 567-578
-
(2006)
N Engl J Med
, vol.354
, pp. 567-578
-
-
Bonner, J.A.1
Harari, P.M.2
Giralt, J.3
-
94
-
-
33745605221
-
Pharmacogenomics and gemcitabine
-
Rosell R, Cobo M, Isla D et al. Pharmacogenomics and gemcitabine. Ann Oncol 2006; 17 Suppl 5: v13-v16
-
(2006)
Ann Oncol
, vol.17
, Issue.SUPPL. 5
-
-
Rosell, R.1
Cobo, M.2
Isla, D.3
-
95
-
-
0042967714
-
Targeted therapy in combination with gemcitabine in non-small cell lung cancer
-
Rosell R, Crino L, Danenberg K et al. Targeted therapy in combination with gemcitabine in non-small cell lung cancer. Semin Oncol 2003; 30: 19-25
-
(2003)
Semin Oncol
, vol.30
, pp. 19-25
-
-
Rosell, R.1
Crino, L.2
Danenberg, K.3
-
96
-
-
34250843259
-
Weighing Tumor Biology in Treatment Decisions for Patients with Non-small Cell Lung Cancer
-
Shepherd FA, Rosell R. Weighing Tumor Biology in Treatment Decisions for Patients with Non-small Cell Lung Cancer. J Thorac Oncol 2007; 2: 68-76
-
(2007)
J Thorac Oncol
, vol.2
, pp. 68-76
-
-
Shepherd, F.A.1
Rosell, R.2
-
97
-
-
12144285914
-
Ribonucleotide reductase messenger RNA expression and survival in gemcitabine/cisplatin-treated advanced non-small cell lung cancer patients
-
Rosell R, Danenberg KD, Alberola V et al. Ribonucleotide reductase messenger RNA expression and survival in gemcitabine/cisplatin-treated advanced non-small cell lung cancer patients. Clin Cancer Res 2004; 10: 1318-1325
-
(2004)
Clin Cancer Res
, vol.10
, pp. 1318-1325
-
-
Rosell, R.1
Danenberg, K.D.2
Alberola, V.3
-
98
-
-
34447567414
-
Feasibility and efficacy of molecular analysis-directed individualized therapy in advanced non-small-cell lung cancer
-
Simon G, Sharma A, Li X et al. Feasibility and efficacy of molecular analysis-directed individualized therapy in advanced non-small-cell lung cancer. J Clin Oncol 2007; 25: 2741-2746
-
(2007)
J Clin Oncol
, vol.25
, pp. 2741-2746
-
-
Simon, G.1
Sharma, A.2
Li, X.3
-
99
-
-
34247097395
-
A phase II study of days 1 and 8 combination of docetaxel plus gemcitabine for the second-line treatment of patients with advanced non-small-cell lung cancer and good performance status
-
Cobo M, Gutierrez V, Alcaide J et al. A phase II study of days 1 and 8 combination of docetaxel plus gemcitabine for the second-line treatment of patients with advanced non-small-cell lung cancer and good performance status. Lung Cancer 2007; 56: 255-262
-
(2007)
Lung Cancer
, vol.56
, pp. 255-262
-
-
Cobo, M.1
Gutierrez, V.2
Alcaide, J.3
-
100
-
-
34447573875
-
Customizing cisplatin based on quantitative excision repair cross-complementing 1 mRNA expression: A phase III trial in non-small-cell lung cancer
-
Cobo M, Isla D, Massuti B et al. Customizing cisplatin based on quantitative excision repair cross-complementing 1 mRNA expression: a phase III trial in non-small-cell lung cancer. J Clin Oncol 2007; 25: 2747-2754
-
(2007)
J Clin Oncol
, vol.25
, pp. 2747-2754
-
-
Cobo, M.1
Isla, D.2
Massuti, B.3
-
102
-
-
23044435044
-
Expression of class III {beta}-tubulin is predictive of patient outcome in patients with non-small cell lung cancer receiving vinorelbine-based chemotherapy
-
Seve P, Isaac S, Tredan O et al. Expression of class III {beta}-tubulin is predictive of patient outcome in patients with non-small cell lung cancer receiving vinorelbine-based chemotherapy. Clin Cancer Res 2005; 11: 5481-5486
-
(2005)
Clin Cancer Res
, vol.11
, pp. 5481-5486
-
-
Seve, P.1
Isaac, S.2
Tredan, O.3
-
103
-
-
30344437279
-
Class III beta-tubulin expression in tumor cells predicts response and outcome in patients with non-small cell lung cancer receiving paclitaxel
-
Seve P, Mackey J, Isaac S et al. Class III beta-tubulin expression in tumor cells predicts response and outcome in patients with non-small cell lung cancer receiving paclitaxel. Mol Cancer Ther 2005; 4: 2001-2007
-
(2005)
Mol Cancer Ther
, vol.4
, pp. 2001-2007
-
-
Seve, P.1
Mackey, J.2
Isaac, S.3
|