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Volumn 61, Issue 11, 2007, Pages 731-740

An approach to individualised therapy of Non-Small Cell Ling Carcinoma (NSCLC) - Relevance of molecular predictive and prognostic factors;Auf dem Weg zu einer individualisierten Therapie des nicht-kleinzelligen Bronchialkarzinoms (NSCLC) - Stellenwert molekularer prädiktions- und prognosefaktoren

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; EXCISION REPAIR CROSS COMPLEMENTING PROTEIN 1; MOLECULAR MARKER; PROTEIN RRM1; UNCLASSIFIED DRUG;

EID: 36749103137     PISSN: 09348387     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-2007-980130     Document Type: Review
Times cited : (5)

References (103)
  • 1
    • 0037844993 scopus 로고    scopus 로고
    • cDNA microarray analysis of gene expression in pathologic Stage IA nonsmall cell lung carcinomas
    • Nakamura H, Saji H, Ogata A et al. cDNA microarray analysis of gene expression in pathologic Stage IA nonsmall cell lung carcinomas. Cancer 2003; 97: 2798-2805
    • (2003) Cancer , vol.97 , pp. 2798-2805
    • Nakamura, H.1    Saji, H.2    Ogata, A.3
  • 2
    • 26644438582 scopus 로고    scopus 로고
    • Small-cell lung cancer
    • Jackman DM, Johnson BE. Small-cell lung cancer. Lancet 2005; 366: 1385-1396
    • (2005) Lancet , vol.366 , pp. 1385-1396
    • Jackman, D.M.1    Johnson, B.E.2
  • 3
    • 0035691670 scopus 로고    scopus 로고
    • The new World Health Organization classification of lung tumours
    • Brambilla E, Travis WD, Colby TV et al. The new World Health Organization classification of lung tumours. Eur Respir J 2001; 18: 1059-1068
    • (2001) Eur Respir J , vol.18 , pp. 1059-1068
    • Brambilla, E.1    Travis, W.D.2    Colby, T.V.3
  • 4
    • 3142683871 scopus 로고    scopus 로고
    • Gene expression-based, individualized outcome prediction for surgically treated lung cancer patients
    • Tomida S, Koshikawa K, Yatabe Y et al. Gene expression-based, individualized outcome prediction for surgically treated lung cancer patients. Oncogene 2004; 23: 5360-5370
    • (2004) Oncogene , vol.23 , pp. 5360-5370
    • Tomida, S.1    Koshikawa, K.2    Yatabe, Y.3
  • 5
    • 20544455590 scopus 로고    scopus 로고
    • Vinorelbine plus cisplatin vs. observation in resected non-small-cell lung cancer
    • Winton T, Livingston R, Johnson D et al. Vinorelbine plus cisplatin vs. observation in resected non-small-cell lung cancer. N Engl J Med 2005; 352: 2589-2597
    • (2005) N Engl J Med , vol.352 , pp. 2589-2597
    • Winton, T.1    Livingston, R.2    Johnson, D.3
  • 6
    • 33747847740 scopus 로고    scopus 로고
    • Adjuvant vinorelbine plus cisplatin versus observation in patients with completely resected stage IB-IIIA non-small-cell lung cancer (Adjuvant Navelbine International Trialist Association [ANITA]): A randomised controlled trial
    • Douillard JY, Rosell R, De Lena M et al. Adjuvant vinorelbine plus cisplatin versus observation in patients with completely resected stage IB-IIIA non-small-cell lung cancer (Adjuvant Navelbine International Trialist Association [ANITA]): a randomised controlled trial. Lancet Oncol 2006; 7: 719-727
    • (2006) Lancet Oncol , vol.7 , pp. 719-727
    • Douillard, J.Y.1    Rosell, R.2    De Lena, M.3
  • 7
    • 0346238665 scopus 로고    scopus 로고
    • Cisplatin-based adjuvant chemotherapy in patients with completely resected non-small-cell lung cancer
    • Arriagada R, Bergman B, Dunant A et al. Cisplatin-based adjuvant chemotherapy in patients with completely resected non-small-cell lung cancer. N Engl J Med 2004; 350: 351-360
    • (2004) N Engl J Med , vol.350 , pp. 351-360
    • Arriagada, R.1    Bergman, B.2    Dunant, A.3
  • 8
    • 0035868913 scopus 로고    scopus 로고
    • Twenty-two years of phase III trials for patients with advanced non-small-cell lung cancer: Sobering results
    • Breathnach OS, Freidlin B, Conley B et al. Twenty-two years of phase III trials for patients with advanced non-small-cell lung cancer: sobering results. J Clin Oncol 2001; 19: 1734-1742
    • (2001) J Clin Oncol , vol.19 , pp. 1734-1742
    • Breathnach, O.S.1    Freidlin, B.2    Conley, B.3
  • 9
    • 33744957443 scopus 로고    scopus 로고
    • Microarray analysis and tumor classification
    • Quackenbush J. Microarray analysis and tumor classification. N Engl J Med 2006; 354: 2463-2472
    • (2006) N Engl J Med , vol.354 , pp. 2463-2472
    • Quackenbush, J.1
  • 10
    • 3042788686 scopus 로고    scopus 로고
    • Tissue preparation for gene expression profiling of colorectal carcinoma: Three alternatives to laser microdissection with preamplification
    • Croner RS, Foertsch T, Siebenhaar R et al. Tissue preparation for gene expression profiling of colorectal carcinoma: Three alternatives to laser microdissection with preamplification. J Lab Clin Med 2004; 143: 344-351
    • (2004) J Lab Clin Med , vol.143 , pp. 344-351
    • Croner, R.S.1    Foertsch, T.2    Siebenhaar, R.3
  • 12
    • 18244409687 scopus 로고    scopus 로고
    • Veer LJ van't, Dai H, Vijver MJ van de et al. Gene expression profiling predicts clinical outcome of breast cancer. Nature 2002; 415: 530-536
    • Veer LJ van't, Dai H, Vijver MJ van de et al. Gene expression profiling predicts clinical outcome of breast cancer. Nature 2002; 415: 530-536
  • 13
    • 0037226593 scopus 로고    scopus 로고
    • A molecular signature of metastasis in primary solid tumors
    • Ramaswamy S, Ross KN, Lander ES et al. A molecular signature of metastasis in primary solid tumors. Nat Genet 2003; 33: 49-54
    • (2003) Nat Genet , vol.33 , pp. 49-54
    • Ramaswamy, S.1    Ross, K.N.2    Lander, E.S.3
  • 14
    • 0033569406 scopus 로고    scopus 로고
    • Molecular classification of cancer: Class discovery and class prediction by gene expression monitoring
    • Golub TR, Slonim DK, Tamayo P et al. Molecular classification of cancer: class discovery and class prediction by gene expression monitoring. Science 1999; 286: 531-537
    • (1999) Science , vol.286 , pp. 531-537
    • Golub, T.R.1    Slonim, D.K.2    Tamayo, P.3
  • 15
    • 21344470901 scopus 로고    scopus 로고
    • Common denominator genes that distinguish colorectal carcinoma from normal mucosa
    • Croner RS, Foertsch T, Brueckl WM et al. Common denominator genes that distinguish colorectal carcinoma from normal mucosa. Int J Colorectal Dis 2005; 20: 353-362
    • (2005) Int J Colorectal Dis , vol.20 , pp. 353-362
    • Croner, R.S.1    Foertsch, T.2    Brueckl, W.M.3
  • 16
    • 0034598746 scopus 로고    scopus 로고
    • Distinct types of diffuse large B-cell lymphoma identified by gene expression profiling
    • Alizadeh AA, Eisen MB, Davis RE et al. Distinct types of diffuse large B-cell lymphoma identified by gene expression profiling. Nature 2000; 403: 503-511
    • (2000) Nature , vol.403 , pp. 503-511
    • Alizadeh, A.A.1    Eisen, M.B.2    Davis, R.E.3
  • 17
    • 33746875641 scopus 로고    scopus 로고
    • A genomic strategy to refine prognosis in early-stage non-small-cell lung cancer
    • Potti A, Mukherjee S, Petersen R et al. A genomic strategy to refine prognosis in early-stage non-small-cell lung cancer. N Engl J Med 2006; 355: 570-580
    • (2006) N Engl J Med , vol.355 , pp. 570-580
    • Potti, A.1    Mukherjee, S.2    Petersen, R.3
  • 18
    • 0035349035 scopus 로고    scopus 로고
    • Criteria for evaluating prognostic factors
    • Hermanek P, Mansmann U. Criteria for evaluating prognostic factors. Chirurg 2001; 72: 474-480
    • (2001) Chirurg , vol.72 , pp. 474-480
    • Hermanek, P.1    Mansmann, U.2
  • 19
    • 0032412988 scopus 로고    scopus 로고
    • Assessing the clinical impact of prognostic factors: When is "statistically significant" clinically useful?
    • Hayes DF, Trock B, Harris AL. Assessing the clinical impact of prognostic factors: when is "statistically significant" clinically useful? Breast Cancer Res Treat 1998; 52: 305-319
    • (1998) Breast Cancer Res Treat , vol.52 , pp. 305-319
    • Hayes, D.F.1    Trock, B.2    Harris, A.L.3
  • 20
    • 33744909361 scopus 로고    scopus 로고
    • From description to causality: Mechanisms of gene expression signatures in cancer
    • Adler AS, Chang HY. From description to causality: mechanisms of gene expression signatures in cancer. Cell Cycle 2006; 5: 1148-1151
    • (2006) Cell Cycle , vol.5 , pp. 1148-1151
    • Adler, A.S.1    Chang, H.Y.2
  • 22
    • 0035909987 scopus 로고    scopus 로고
    • Molecular characteristics of non-small cell lung cancer
    • Nacht M, Dracheva T, Gao Y et al. Molecular characteristics of non-small cell lung cancer. Proc Natl Acad Sci U S A 2001; 98: 15 203-15 208
    • (2001) Proc Natl Acad Sci U S A , vol.98
    • Nacht, M.1    Dracheva, T.2    Gao, Y.3
  • 23
    • 0037126055 scopus 로고    scopus 로고
    • Integrated classification of lung tumors and cell lines by expression profiling
    • Virtanen C, Ishikawa Y, Honjoh D et al. Integrated classification of lung tumors and cell lines by expression profiling. Proc Natl Acad Sci U S A 2002; 99: 12 357-12 362
    • (2002) Proc Natl Acad Sci U S A , vol.99
    • Virtanen, C.1    Ishikawa, Y.2    Honjoh, D.3
  • 24
    • 0142151074 scopus 로고    scopus 로고
    • Non-small-cell lung cancer molecular signatures recapitulate lung developmental pathways
    • Borczuk AC, Gorenstein L, Walter KL et al. Non-small-cell lung cancer molecular signatures recapitulate lung developmental pathways. Am J Pathol 2003; 163: 1949-1960
    • (2003) Am J Pathol , vol.163 , pp. 1949-1960
    • Borczuk, A.C.1    Gorenstein, L.2    Walter, K.L.3
  • 25
    • 22044453790 scopus 로고    scopus 로고
    • Erlotinib in lung cancer - molecular and clinical predictors of outcome
    • Tsao MS, Sakurada A, Cutz JC et al. Erlotinib in lung cancer - molecular and clinical predictors of outcome. N Engl J Med 2005; 353: 133-144
    • (2005) N Engl J Med , vol.353 , pp. 133-144
    • Tsao, M.S.1    Sakurada, A.2    Cutz, J.C.3
  • 26
    • 34447130180 scopus 로고    scopus 로고
    • FDA drug approval summary: Bevacizumab (Avastin) plus Carboplatin and Paclitaxel as first-line treatment of advanced/metastatic recurrent nonsquamous non-small cell lung cancer
    • Cohen MH, Gootenberg J, Keegan P et al. FDA drug approval summary: bevacizumab (Avastin) plus Carboplatin and Paclitaxel as first-line treatment of advanced/metastatic recurrent nonsquamous non-small cell lung cancer. Oncologist 2007; 12: 713-718
    • (2007) Oncologist , vol.12 , pp. 713-718
    • Cohen, M.H.1    Gootenberg, J.2    Keegan, P.3
  • 27
    • 33845490014 scopus 로고    scopus 로고
    • Paclitaxel-carboplatin alone or with bevacizumab for non-small-cell lung cancer
    • Sandler A, Gray R, Perry MC et al. Paclitaxel-carboplatin alone or with bevacizumab for non-small-cell lung cancer. N Engl J Med 2006; 355: 2542-2550
    • (2006) N Engl J Med , vol.355 , pp. 2542-2550
    • Sandler, A.1    Gray, R.2    Perry, M.C.3
  • 28
    • 33750144030 scopus 로고    scopus 로고
    • Advanced non-small-cell lung cancer: New data, therapy choices, and challenging decisions
    • Sandler AB. Advanced non-small-cell lung cancer: new data, therapy choices, and challenging decisions. Oncology 2006; 20: 626-628
    • (2006) Oncology , vol.20 , pp. 626-628
    • AB, S.1
  • 29
    • 2942657615 scopus 로고    scopus 로고
    • Randomized phase II trial comparing bevacizumab plus carboplatin and paclitaxel with carboplatin and paclitaxel alone in previously untreated locally advanced or metastatic non-small-cell lung cancer
    • Johnson DH, Fehrenbacher L, Novotny WF et al. Randomized phase II trial comparing bevacizumab plus carboplatin and paclitaxel with carboplatin and paclitaxel alone in previously untreated locally advanced or metastatic non-small-cell lung cancer. J Clin Oncol 2004; 22: 2184-2191
    • (2004) J Clin Oncol , vol.22 , pp. 2184-2191
    • Johnson, D.H.1    Fehrenbacher, L.2    Novotny, W.F.3
  • 30
    • 0030912190 scopus 로고    scopus 로고
    • Revisions in the International System for Staging Lung Cancer
    • Mountain CF. Revisions in the International System for Staging Lung Cancer. Chest 1997; 111: 1710-1717
    • (1997) Chest , vol.111 , pp. 1710-1717
    • CF, M.1
  • 31
    • 0031892132 scopus 로고    scopus 로고
    • Functional evaluation of the lung resection candidate
    • Bolliger CT, Perruchoud AP. Functional evaluation of the lung resection candidate. Eur Respir J 1998; 11: 198-212
    • (1998) Eur Respir J , vol.11 , pp. 198-212
    • Bolliger, C.T.1    Perruchoud, A.P.2
  • 32
    • 33846011470 scopus 로고    scopus 로고
    • A five-gene signature and clinical outcome in non-small-cell lung cancer
    • Chen HY, Yu SL, Chen CH et al. A five-gene signature and clinical outcome in non-small-cell lung cancer. N Engl J Med 2007; 356: 11-20
    • (2007) N Engl J Med , vol.356 , pp. 11-20
    • Chen, H.Y.1    Yu, S.L.2    Chen, C.H.3
  • 33
    • 34249704163 scopus 로고    scopus 로고
    • Referral patterns for adjuvant chemotherapy in patients with completely resected non-small cell lung cancer
    • Kassam F, Shepherd FA, Johnston M et al. Referral patterns for adjuvant chemotherapy in patients with completely resected non-small cell lung cancer. J Thorac Oncol 2007; 2: 39-43
    • (2007) J Thorac Oncol , vol.2 , pp. 39-43
    • Kassam, F.1    Shepherd, F.A.2    Johnston, M.3
  • 34
    • 33747820148 scopus 로고    scopus 로고
    • Lung Adjuvant Cisplatin Evaluation (LACE): A pooled analysis of five randomized clicial trials including 4,584 patients
    • 366s
    • Pignon JP, Tribodet H, Scagliotti GV et al. Lung Adjuvant Cisplatin Evaluation (LACE): a pooled analysis of five randomized clicial trials including 4,584 patients. Proc Am Soc Clin Oncol 2006; 24: 366s
    • (2006) Proc Am Soc Clin Oncol , vol.24
    • Pignon, J.P.1    Tribodet, H.2    Scagliotti, G.V.3
  • 35
    • 34147158870 scopus 로고    scopus 로고
    • Optimal adjuvant therapy for non-small cell lung cancer - how to handle stage I disease
    • Wakelee H, Dubey S, Gandara D. Optimal adjuvant therapy for non-small cell lung cancer - how to handle stage I disease. Oncologist 2007; 12: 331-337
    • (2007) Oncologist , vol.12 , pp. 331-337
    • Wakelee, H.1    Dubey, S.2    Gandara, D.3
  • 36
    • 0027949292 scopus 로고
    • A placebo-controlled randomized double-blind study of adjuvant intrapleural BCG in patients with resected T1N0, T1N1, or T2N0 squamous cell carcinoma, adenocarcinoma, or large cell carcinoma of the lung. LCSG Protocol 771
    • Gail MH. A placebo-controlled randomized double-blind study of adjuvant intrapleural BCG in patients with resected T1N0, T1N1, or T2N0 squamous cell carcinoma, adenocarcinoma, or large cell carcinoma of the lung. LCSG Protocol 771. Chest 1994; 106: 287S-292S
    • (1994) Chest , vol.106
    • MH, G.1
  • 37
    • 17144449993 scopus 로고    scopus 로고
    • Surgery in locally advanced non-small cell lung cancer
    • Naruke T. Surgery in locally advanced non-small cell lung cancer. Lung Cancer 2003; 42 Suppl 2: S11-15
    • (2003) Lung Cancer , vol.42 , Issue.SUPPL. 2
    • Naruke, T.1
  • 38
    • 33748487809 scopus 로고    scopus 로고
    • Pharmacologic treatment of bronchial cancer. Part 1: Standards
    • Serke M. Pharmacologic treatment of bronchial cancer. Part 1: Standards. Pneumologie 2006; 60: 493-508
    • (2006) Pneumologie , vol.60 , pp. 493-508
    • Serke, M.1
  • 39
    • 33845494722 scopus 로고    scopus 로고
    • Cecere F, Bria E, Resell R. DNA repair by ERCC1 in non-small-cell lung cancer. N Engl J Med 2006; 355: 2590-2591 author reply 2591
    • Cecere F, Bria E, Resell R. DNA repair by ERCC1 in non-small-cell lung cancer. N Engl J Med 2006; 355: 2590-2591 author reply 2591
  • 40
    • 33845472882 scopus 로고    scopus 로고
    • DNA repair by ERCC1 in non-small-cell lung cancer
    • Grenader T, Shavit L. DNA repair by ERCC1 in non-small-cell lung cancer. N Engl J Med 2006; 355: 2591
    • (2006) N Engl J Med , vol.355 , pp. 2591
    • Grenader, T.1    Shavit, L.2
  • 41
    • 24344456401 scopus 로고    scopus 로고
    • ERCC1 and clinical resistance to platinum-based therapy
    • Reed E. ERCC1 and clinical resistance to platinum-based therapy. Clin Cancer Res 2005; 11: 6100-6102
    • (2005) Clin Cancer Res , vol.11 , pp. 6100-6102
    • Reed, E.1
  • 42
    • 0031982522 scopus 로고    scopus 로고
    • ERCC1 mRNA levels complement thymidylate synthase mRNA levels in predicting response and survival for gastric cancer patients receiving combination cisplatin and fluorouracil chemotherapy
    • Metzger R, Leichman CG, Danenberg KD et al. ERCC1 mRNA levels complement thymidylate synthase mRNA levels in predicting response and survival for gastric cancer patients receiving combination cisplatin and fluorouracil chemotherapy. J Clin Oncol 1998; 16: 309-316
    • (1998) J Clin Oncol , vol.16 , pp. 309-316
    • Metzger, R.1    Leichman, C.G.2    Danenberg, K.D.3
  • 43
    • 0028141961 scopus 로고
    • Messenger RNA levels of XPAC and ERCC1 in ovarian cancer tissue correlate with response to platinum-based chemotherapy
    • Dabholkar M, Vionnet J, Bostick-Bruton F et al. Messenger RNA levels of XPAC and ERCC1 in ovarian cancer tissue correlate with response to platinum-based chemotherapy. J Clin Invest 1994; 94: 703-708
    • (1994) J Clin Invest , vol.94 , pp. 703-708
    • Dabholkar, M.1    Vionnet, J.2    Bostick-Bruton, F.3
  • 44
    • 0035988959 scopus 로고    scopus 로고
    • Low ERCC1 expression correlates with prolonged survival after cisplatin plus gemcitabine chemotherapy in non-small cell lung cancer
    • Lord RV, Brabender J, Gandara D et al. Low ERCC1 expression correlates with prolonged survival after cisplatin plus gemcitabine chemotherapy in non-small cell lung cancer. Clin Cancer Res 2002; 8: 2286-2291
    • (2002) Clin Cancer Res , vol.8 , pp. 2286-2291
    • Lord, R.V.1    Brabender, J.2    Gandara, D.3
  • 45
    • 33748435058 scopus 로고    scopus 로고
    • DNA repair by ERCC1 in non-small-cell lung cancer and cisplatin-based adjuvant chemotherapy
    • Olaussen KA, Dunant A, Fouret P et al. DNA repair by ERCC1 in non-small-cell lung cancer and cisplatin-based adjuvant chemotherapy. N Engl J Med 2006; 355: 983-991
    • (2006) N Engl J Med , vol.355 , pp. 983-991
    • Olaussen, K.A.1    Dunant, A.2    Fouret, P.3
  • 46
    • 34249819963 scopus 로고    scopus 로고
    • Olaussen KA, Mountzios G, Soria JC. ERCC1 as a risk stratifier in platinum-based chemotherapy for nonsmall-cell lung cancer. Curr Opin Pulm Med 2007; 13: 284-289
    • Olaussen KA, Mountzios G, Soria JC. ERCC1 as a risk stratifier in platinum-based chemotherapy for nonsmall-cell lung cancer. Curr Opin Pulm Med 2007; 13: 284-289
  • 47
    • 33847107236 scopus 로고    scopus 로고
    • DNA synthesis and repair genes RRM1 and ERCC1 in lung cancer
    • Zheng Z, Chen T, Li X et al. DNA synthesis and repair genes RRM1 and ERCC1 in lung cancer. N Engl J Med 2007; 356: 800-808
    • (2007) N Engl J Med , vol.356 , pp. 800-808
    • Zheng, Z.1    Chen, T.2    Li, X.3
  • 48
    • 27744446615 scopus 로고    scopus 로고
    • Using translational research to tailor the use of chemotherapy in the treatment of NSCLC
    • Bepler G. Using translational research to tailor the use of chemotherapy in the treatment of NSCLC. Lung Cancer 2005; 50 Suppl 1: S13-34
    • (2005) Lung Cancer , vol.50 , Issue.SUPPL. 1
    • Bepler, G.1
  • 49
    • 21044445279 scopus 로고    scopus 로고
    • Mutation in the tyrosine kinase domain of epidermal growth factor receptor is a predictive and prognostic factor for gefitinib treatment in patients with non-small cell lung cancer
    • Chou TY, Chiu CH, Li LH et al. Mutation in the tyrosine kinase domain of epidermal growth factor receptor is a predictive and prognostic factor for gefitinib treatment in patients with non-small cell lung cancer. Clin Cancer Res 2005; 11: 3750-3757
    • (2005) Clin Cancer Res , vol.11 , pp. 3750-3757
    • Chou, T.Y.1    Chiu, C.H.2    Li, L.H.3
  • 50
    • 0028843552 scopus 로고
    • Chemotherapy in non-small cell lung cancer: A meta-analysis using updated data on individual patients from 52 randomised clinical trials
    • Non-small Cell Lung Cancer Collaborative Group
    • Non-small Cell Lung Cancer Collaborative Group. Chemotherapy in non-small cell lung cancer: a meta-analysis using updated data on individual patients from 52 randomised clinical trials. Bmj 1995; 311: 899-909
    • (1995) Bmj , vol.311 , pp. 899-909
  • 51
    • 33745152761 scopus 로고    scopus 로고
    • Lung cancer
    • quiz 621
    • Huber RM. Lung cancer. Internist 2006; 47: 611-620 quiz 621
    • (2006) Internist , vol.47 , pp. 611-620
    • RM, H.1
  • 52
    • 1242318822 scopus 로고    scopus 로고
    • State-of-the-art chemotherapy for advanced non-small cell lung cancer
    • Ramalingam S, Belani CP. State-of-the-art chemotherapy for advanced non-small cell lung cancer. Semin Oncol 2004; 31: 68-74
    • (2004) Semin Oncol , vol.31 , pp. 68-74
    • Ramalingam, S.1    Belani, C.P.2
  • 53
    • 0034069620 scopus 로고    scopus 로고
    • Prospective randomized trial of docetaxel versus best supportive care in patients with non-small-cell lung cancer previously treated with platinum-based chemotherapy
    • Shepherd FA, Dancey J, Ramlau R et al. Prospective randomized trial of docetaxel versus best supportive care in patients with non-small-cell lung cancer previously treated with platinum-based chemotherapy. J Clin Oncol 2000; 18: 2095-2103
    • (2000) J Clin Oncol , vol.18 , pp. 2095-2103
    • Shepherd, F.A.1    Dancey, J.2    Ramlau, R.3
  • 54
    • 22044445517 scopus 로고    scopus 로고
    • Erlotinib in previously treated non-small-cell lung cancer
    • Shepherd FA, Rodrigues PereiraJ, Ciuleanu T et al. Erlotinib in previously treated non-small-cell lung cancer. N Engl J Med 2005; 353: 123-132
    • (2005) N Engl J Med , vol.353 , pp. 123-132
    • Shepherd, F.A.1    PereiraJ, R.2    Ciuleanu, T.3
  • 55
    • 2442661845 scopus 로고    scopus 로고
    • Randomized phase III trial of pemetrexed versus docetaxel in patients with non-small-cell lung cancer previously treated with chemotherapy
    • Hanna N, Shepherd FA, Fossella FV et al. Randomized phase III trial of pemetrexed versus docetaxel in patients with non-small-cell lung cancer previously treated with chemotherapy. J Clin Oncol 2004; 22: 1589-1597
    • (2004) J Clin Oncol , vol.22 , pp. 1589-1597
    • Hanna, N.1    Shepherd, F.A.2    Fossella, F.V.3
  • 56
    • 0037838557 scopus 로고    scopus 로고
    • Development of the epidermal growth factor receptor inhibitor OSI-774
    • Grunwald V, Hidalgo M. Development of the epidermal growth factor receptor inhibitor OSI-774. Semin Oncol 2003; 30: 23-31
    • (2003) Semin Oncol , vol.30 , pp. 23-31
    • Grunwald, V.1    Hidalgo, M.2
  • 57
    • 0030774045 scopus 로고    scopus 로고
    • Induction of apoptosis and cell cycle arrest by CP-358,774, an inhibitor of epidermal growth factor receptor tyrosine kinase
    • Moyer JD, Barbacci EG, Iwata KK et al. Induction of apoptosis and cell cycle arrest by CP-358,774, an inhibitor of epidermal growth factor receptor tyrosine kinase. Cancer Res 1997; 57: 4838-4848
    • (1997) Cancer Res , vol.57 , pp. 4838-4848
    • Moyer, J.D.1    Barbacci, E.G.2    Iwata, K.K.3
  • 58
    • 0032695910 scopus 로고    scopus 로고
    • Inhibition of epidermal growth factor receptor-associated tyrosine phosphorylation in human carcinomas with CP-358,774: Dynamics of receptor inhibition in situ and antitumor effects in athymic mice
    • Pollack VA, Savage DM, Baker DA et al. Inhibition of epidermal growth factor receptor-associated tyrosine phosphorylation in human carcinomas with CP-358,774: dynamics of receptor inhibition in situ and antitumor effects in athymic mice. J Pharmacol Exp Ther 1999; 291: 739-748
    • (1999) J Pharmacol Exp Ther , vol.291 , pp. 739-748
    • Pollack, V.A.1    Savage, D.M.2    Baker, D.A.3
  • 60
    • 0023187984 scopus 로고
    • Molecular evidence for the lack of epidermal growth factor receptor gene expression in small cell lung carcinoma cells
    • Gamou S, Hunts J, Harigai H et al. Molecular evidence for the lack of epidermal growth factor receptor gene expression in small cell lung carcinoma cells. Cancer Res 1987; 47: 2668-2673
    • (1987) Cancer Res , vol.47 , pp. 2668-2673
    • Gamou, S.1    Hunts, J.2    Harigai, H.3
  • 61
    • 20044364940 scopus 로고    scopus 로고
    • Clinical and biological features associated with epidermal growth factor receptor gene mutations in lung cancers
    • Shigematsu H, Lin L, Takahashi T et al. Clinical and biological features associated with epidermal growth factor receptor gene mutations in lung cancers. J Natl Cancer Inst 2005; 97: 339-346
    • (2005) J Natl Cancer Inst , vol.97 , pp. 339-346
    • Shigematsu, H.1    Lin, L.2    Takahashi, T.3
  • 62
    • 4143051317 scopus 로고    scopus 로고
    • Excision repair cross-complementation group 1 polymorphism predicts overall survival in advanced non-small cell lung cancer patients treated with platinum-based chemotherapy
    • Zhou W, Gurubhagavatula S, Liu G et al. Excision repair cross-complementation group 1 polymorphism predicts overall survival in advanced non-small cell lung cancer patients treated with platinum-based chemotherapy. Clin Cancer Res 2004; 10: 4939-4943
    • (2004) Clin Cancer Res , vol.10 , pp. 4939-4943
    • Zhou, W.1    Gurubhagavatula, S.2    Liu, G.3
  • 63
    • 20044364933 scopus 로고    scopus 로고
    • EGFR mutations in non-small-cell lung cancer: Analysis of a large series of cases and development of a rapid and sensitive method for diagnostic screening with potential implications on pharmacologic treatment
    • Marchetti A, Martella C, Felicioni L et al. EGFR mutations in non-small-cell lung cancer: analysis of a large series of cases and development of a rapid and sensitive method for diagnostic screening with potential implications on pharmacologic treatment. J Clin Oncol 2005; 23: 857-865
    • (2005) J Clin Oncol , vol.23 , pp. 857-865
    • Marchetti, A.1    Martella, C.2    Felicioni, L.3
  • 64
    • 20244388126 scopus 로고    scopus 로고
    • Mutations of the epidermal growth factor receptor gene predict prolonged survival after gefitinib treatment in patients with non-small-cell lung cancer with postoperative recurrence
    • Mitsudomi T, Kosaka T, Endoh H et al. Mutations of the epidermal growth factor receptor gene predict prolonged survival after gefitinib treatment in patients with non-small-cell lung cancer with postoperative recurrence. J Clin Oncol 2005; 23: 2513-2520
    • (2005) J Clin Oncol , vol.23 , pp. 2513-2520
    • Mitsudomi, T.1    Kosaka, T.2    Endoh, H.3
  • 65
    • 10844231985 scopus 로고    scopus 로고
    • Mutations of the epidermal growth factor receptor gene in lung cancer: Biological and clinical implications
    • Kosaka T, Yatabe Y, Endoh H et al. Mutations of the epidermal growth factor receptor gene in lung cancer: biological and clinical implications. Cancer Res 2004; 64: 8919-8923
    • (2004) Cancer Res , vol.64 , pp. 8919-8923
    • Kosaka, T.1    Yatabe, Y.2    Endoh, H.3
  • 66
    • 33746034167 scopus 로고    scopus 로고
    • Exon 19 deletion mutations of epidermal growth factor receptor are associated with prolonged survival in non-small cell lung cancer patients treated with gefitinib or erlotinib
    • Jackman DM, Yeap BY, Sequist LV et al. Exon 19 deletion mutations of epidermal growth factor receptor are associated with prolonged survival in non-small cell lung cancer patients treated with gefitinib or erlotinib. Clin Cancer Res 2006; 12: 3908-3914
    • (2006) Clin Cancer Res , vol.12 , pp. 3908-3914
    • Jackman, D.M.1    Yeap, B.Y.2    Sequist, L.V.3
  • 67
    • 27744499056 scopus 로고    scopus 로고
    • Combining EGFR targeted therapy with chemotherapy in pancreatic cancer: Is timing important?
    • Riely GJ, Pao W. Combining EGFR targeted therapy with chemotherapy in pancreatic cancer: is timing important? Cancer Biol Ther 2005; 4: 1096-1097
    • (2005) Cancer Biol Ther , vol.4 , pp. 1096-1097
    • Riely, G.J.1    Pao, W.2
  • 68
    • 20444498630 scopus 로고    scopus 로고
    • Epidermal growth factor receptor gene and protein and gefitinib sensitivity in non-small-cell lung cancer
    • Cappuzzo F, Hirsch FR, Rossi E et al. Epidermal growth factor receptor gene and protein and gefitinib sensitivity in non-small-cell lung cancer. J Natl Cancer Inst 2005; 97: 643-655
    • (2005) J Natl Cancer Inst , vol.97 , pp. 643-655
    • Cappuzzo, F.1    Hirsch, F.R.2    Rossi, E.3
  • 69
    • 20244389188 scopus 로고    scopus 로고
    • Predictive and prognostic impact of epidermal growth factor receptor mutation in non-small-cell lung cancer patients treated with gefitinib
    • Han SW, Kim TY, Hwang PG et al. Predictive and prognostic impact of epidermal growth factor receptor mutation in non-small-cell lung cancer patients treated with gefitinib. J Clin Oncol 2005; 23: 2493-2501
    • (2005) J Clin Oncol , vol.23 , pp. 2493-2501
    • Han, S.W.1    Kim, T.Y.2    Hwang, P.G.3
  • 70
    • 27244451321 scopus 로고    scopus 로고
    • Epidermal growth factor receptor gene mutations and increased copy numbers predict gefitinib sensitivity in patients with recurrent non-small-cell lung cancer
    • Takano T, Ohe Y, Sakamoto H et al. Epidermal growth factor receptor gene mutations and increased copy numbers predict gefitinib sensitivity in patients with recurrent non-small-cell lung cancer. J Clin Oncol 2005; 23: 6829-6837
    • (2005) J Clin Oncol , vol.23 , pp. 6829-6837
    • Takano, T.1    Ohe, Y.2    Sakamoto, H.3
  • 71
    • 23844490782 scopus 로고    scopus 로고
    • Activating mutations in the tyrosine kinase domain of the epidermal growth factor receptor are associated with improved survival in gefitinib-treated chemorefractory lung adenocarcinomas
    • Taron M, Ichinose Y, Resell R et al. Activating mutations in the tyrosine kinase domain of the epidermal growth factor receptor are associated with improved survival in gefitinib-treated chemorefractory lung adenocarcinomas. Clin Cancer Res 2005; 11: 5878-5885
    • (2005) Clin Cancer Res , vol.11 , pp. 5878-5885
    • Taron, M.1    Ichinose, Y.2    Resell, R.3
  • 72
    • 23844517762 scopus 로고    scopus 로고
    • The EGFR mutation and its correlation with response of gefitinib in previously treated Chinese patients with advanced non-small-cell lung cancer
    • Zhang XT, Li LY, Mu XL et al. The EGFR mutation and its correlation with response of gefitinib in previously treated Chinese patients with advanced non-small-cell lung cancer. Ann Oncol 2005; 16: 1334-1342
    • (2005) Ann Oncol , vol.16 , pp. 1334-1342
    • Zhang, X.T.1    Li, L.Y.2    Mu, X.L.3
  • 73
    • 28844461559 scopus 로고    scopus 로고
    • Common EGFR mutations conferring sensitivity to gefitinib in lung adenocarcinoma are not prevalent in human malignant mesothelioma
    • Cortese JF, Gowda AL, Wali A et al. Common EGFR mutations conferring sensitivity to gefitinib in lung adenocarcinoma are not prevalent in human malignant mesothelioma. Int J Cancer 2006; 118: 521-522
    • (2006) Int J Cancer , vol.118 , pp. 521-522
    • Cortese, J.F.1    Gowda, A.L.2    Wali, A.3
  • 74
    • 33750205340 scopus 로고    scopus 로고
    • A phase II trial of gefitinib as first-line therapy for advanced non-small cell lung cancer with epidermal growth factor receptor mutations
    • Asahina H, Yamazaki K, Kinoshita I et al. A phase II trial of gefitinib as first-line therapy for advanced non-small cell lung cancer with epidermal growth factor receptor mutations. Br J Cancer 2006; 95: 998-1004
    • (2006) Br J Cancer , vol.95 , pp. 998-1004
    • Asahina, H.1    Yamazaki, K.2    Kinoshita, I.3
  • 75
    • 34347368906 scopus 로고    scopus 로고
    • Setting the benchmark for tailoring treatment with EGFR tyrosine kinase inhibitors
    • Rosell R, Taron M, Sanchez JJ et al. Setting the benchmark for tailoring treatment with EGFR tyrosine kinase inhibitors. Future Oncol 2007; 3: 277-283
    • (2007) Future Oncol , vol.3 , pp. 277-283
    • Rosell, R.1    Taron, M.2    Sanchez, J.J.3
  • 76
    • 33746789922 scopus 로고    scopus 로고
    • Prospective phase II study of gefitinib for chemotherapy-naive patients with advanced non-small-cell lung cancer with epidermal growth factor receptor gene mutations
    • Inoue A, Suzuki T, Fukuhara T et al. Prospective phase II study of gefitinib for chemotherapy-naive patients with advanced non-small-cell lung cancer with epidermal growth factor receptor gene mutations. J Clin Oncol 2006; 24: 3340-3346
    • (2006) J Clin Oncol , vol.24 , pp. 3340-3346
    • Inoue, A.1    Suzuki, T.2    Fukuhara, T.3
  • 77
    • 33845434121 scopus 로고    scopus 로고
    • A prospective phase II trial of erlotinib in advanced non-small cell lung cancer patients with mutations in the tyrosine kinase domain of the EGF-R
    • Paz-Ares L, Sanchez IM, Garcia-Velasco A et al. A prospective phase II trial of erlotinib in advanced non-small cell lung cancer patients with mutations in the tyrosine kinase domain of the EGF-R Proc. ASCO 2006; 24: 7020
    • (2006) Proc. ASCO , vol.24 , pp. 7020
    • Paz-Ares, L.1    Sanchez, I.M.2    Garcia-Velasco, A.3
  • 78
    • 33947498978 scopus 로고    scopus 로고
    • Molecular predictors of response to epidermal growth factor receptor antagonists in non-small-cell lung cancer
    • Sequist LV, Bell DW, Lynch TJ et al. Molecular predictors of response to epidermal growth factor receptor antagonists in non-small-cell lung cancer. J Clin Oncol 2007; 25: 587-595
    • (2007) J Clin Oncol , vol.25 , pp. 587-595
    • Sequist, L.V.1    Bell, D.W.2    Lynch, T.J.3
  • 79
    • 13844317894 scopus 로고    scopus 로고
    • EGFR mutation and resistance of non-small-cell lung cancer to gefitinib
    • Kobayashi S, Boggon TJ, Dayaram T et al. EGFR mutation and resistance of non-small-cell lung cancer to gefitinib. N Engl J Med 2005; 352: 786-792
    • (2005) N Engl J Med , vol.352 , pp. 786-792
    • Kobayashi, S.1    Boggon, T.J.2    Dayaram, T.3
  • 80
    • 18244371651 scopus 로고    scopus 로고
    • Acquired resistance of lung adenocarcinomas to gefitinib or erlotinib is associated with a second mutation in the EGFR kinase domain
    • Pao W, Miller VA, Politi KA et al. Acquired resistance of lung adenocarcinomas to gefitinib or erlotinib is associated with a second mutation in the EGFR kinase domain. PLoS Med 2005; 2: e73
    • (2005) PLoS Med , vol.2
    • Pao, W.1    Miller, V.A.2    Politi, K.A.3
  • 81
    • 21144439000 scopus 로고    scopus 로고
    • Irreversible inhibitors of the EGF receptor may circumvent acquired resistance to gefitinib
    • Kwak EL, Sordella R, Bell DW et al. Irreversible inhibitors of the EGF receptor may circumvent acquired resistance to gefitinib. Proc Natl Acad Sci U S A 2005; 102: 7665-7670
    • (2005) Proc Natl Acad Sci U S A , vol.102 , pp. 7665-7670
    • Kwak, E.L.1    Sordella, R.2    Bell, D.W.3
  • 82
    • 33646418681 scopus 로고    scopus 로고
    • Optimization of patient selection for gefitinib in non-small cell lung cancer by combined analysis of epidermal growth factor receptor mutation, K-ras mutation, and Akt phosphorylation
    • Han SW, Kim TY, Jeon YK et al. Optimization of patient selection for gefitinib in non-small cell lung cancer by combined analysis of epidermal growth factor receptor mutation, K-ras mutation, and Akt phosphorylation. Clin Cancer Res 2006; 12: 2538-2544
    • (2006) Clin Cancer Res , vol.12 , pp. 2538-2544
    • Han, S.W.1    Kim, T.Y.2    Jeon, Y.K.3
  • 83
    • 15744372810 scopus 로고    scopus 로고
    • KRAS mutations and primary resistance of lung adenocarcinomas to gefitinib or erlotinib
    • Pao W, Wang TY, Riely GJ et al. KRAS mutations and primary resistance of lung adenocarcinomas to gefitinib or erlotinib. PLoS Med 2005; 2: e17
    • (2005) PLoS Med , vol.2
    • Pao, W.1    Wang, T.Y.2    Riely, G.J.3
  • 84
    • 24944497744 scopus 로고    scopus 로고
    • Mutations in the epidermal growth factor receptor and in KRAS are predictive and prognostic indicators in patients with non-small-cell lung cancer treated with chemotherapy alone and in combination with erlotinib
    • Eberhard DA, Johnson BE, Amler LC et al. Mutations in the epidermal growth factor receptor and in KRAS are predictive and prognostic indicators in patients with non-small-cell lung cancer treated with chemotherapy alone and in combination with erlotinib. J Clin Oncol 2005; 23: 5900-5909
    • (2005) J Clin Oncol , vol.23 , pp. 5900-5909
    • Eberhard, D.A.1    Johnson, B.E.2    Amler, L.C.3
  • 85
    • 33644822965 scopus 로고    scopus 로고
    • Epidermal growth factor receptor inhibitors in lung cancer: Smaller or larger molecules, selected or unselected populations?
    • Hirsch FR, Bunn JrPA. Epidermal growth factor receptor inhibitors in lung cancer: smaller or larger molecules, selected or unselected populations? J Clin Oncol 2005; 23: 9044-9047
    • (2005) J Clin Oncol , vol.23 , pp. 9044-9047
    • Hirsch, F.R.1    JrPA, B.2
  • 86
    • 28844449401 scopus 로고    scopus 로고
    • Epidermal growth factor receptor mutations and gene amplification in non-small-cell lung cancer: Molecular analysis of the IDEAL/INTACT gefitinib trials
    • Bell DW, Lynch TJ, Haserlat SM et al. Epidermal growth factor receptor mutations and gene amplification in non-small-cell lung cancer: molecular analysis of the IDEAL/INTACT gefitinib trials. J Clin Oncol 2005; 23: 8081-8092
    • (2005) J Clin Oncol , vol.23 , pp. 8081-8092
    • Bell, D.W.1    Lynch, T.J.2    Haserlat, S.M.3
  • 87
    • 23844491524 scopus 로고    scopus 로고
    • Differential effects of gefitinib and cetuximab on non-small-cell lung cancers bearing epidermal growth factor receptor mutations
    • Mukohara T, Engelman JA, Hanna NH et al. Differential effects of gefitinib and cetuximab on non-small-cell lung cancers bearing epidermal growth factor receptor mutations. J Natl Cancer Inst 2005; 97: 1185-1194
    • (2005) J Natl Cancer Inst , vol.97 , pp. 1185-1194
    • Mukohara, T.1    Engelman, J.A.2    Hanna, N.H.3
  • 88
    • 33947415279 scopus 로고    scopus 로고
    • Phase II trial of cetuximab inpatients with previously treated non-small-cell lung cancer
    • Hanna N, Lilenbaum R, Ansari R et al. Phase II trial of cetuximab inpatients with previously treated non-small-cell lung cancer. J Clin Oncol 2006; 24: 5253-5258
    • (2006) J Clin Oncol , vol.24 , pp. 5253-5258
    • Hanna, N.1    Lilenbaum, R.2    Ansari, R.3
  • 89
    • 0038418869 scopus 로고    scopus 로고
    • Chk1 and Chk2 kinases in checkpoint control and cancer
    • Bartek J, Lukas J. Chk1 and Chk2 kinases in checkpoint control and cancer. Cancer Cell 2003; 3: 421-429
    • (2003) Cancer Cell , vol.3 , pp. 421-429
    • Bartek, J.1    Lukas, J.2
  • 90
    • 0036510055 scopus 로고    scopus 로고
    • The DNA damage-dependent intra-S phase checkpoint is regulated by parallel pathways
    • Falck J, Petrini JH, Williams BR et al. The DNA damage-dependent intra-S phase checkpoint is regulated by parallel pathways. Nat Genet 2002; 30: 290-394
    • (2002) Nat Genet , vol.30 , pp. 290-394
    • Falck, J.1    Petrini, J.H.2    Williams, B.R.3
  • 91
    • 33750339641 scopus 로고    scopus 로고
    • Non-Small Cell Lung Cancers with Kinase Domain Mutations in the Epidermal Growth Factor Receptor Are Sensitive to Ionizing Radiation
    • Das AK, Sato M, Story MD et al. Non-Small Cell Lung Cancers with Kinase Domain Mutations in the Epidermal Growth Factor Receptor Are Sensitive to Ionizing Radiation. Cancer Res 2006; 66: 9601-9608
    • (2006) Cancer Res , vol.66 , pp. 9601-9608
    • Das, A.K.1    Sato, M.2    Story, M.D.3
  • 92
    • 19944427144 scopus 로고    scopus 로고
    • The effects of cetuximab alone and in combination with radiation and/or chemotherapy in lung cancer
    • Raben D, Helfrich B, Chan DC et al. The effects of cetuximab alone and in combination with radiation and/or chemotherapy in lung cancer. Clin Cancer Res 2005; 11: 795-805
    • (2005) Clin Cancer Res , vol.11 , pp. 795-805
    • Raben, D.1    Helfrich, B.2    Chan, D.C.3
  • 93
    • 32144433159 scopus 로고    scopus 로고
    • Radiotherapy plus cetuximab for squamous-cell carcinoma of the head and neck
    • Bonner JA, Harari PM, Giralt J et al. Radiotherapy plus cetuximab for squamous-cell carcinoma of the head and neck. N Engl J Med 2006; 354: 567-578
    • (2006) N Engl J Med , vol.354 , pp. 567-578
    • Bonner, J.A.1    Harari, P.M.2    Giralt, J.3
  • 94
    • 33745605221 scopus 로고    scopus 로고
    • Pharmacogenomics and gemcitabine
    • Rosell R, Cobo M, Isla D et al. Pharmacogenomics and gemcitabine. Ann Oncol 2006; 17 Suppl 5: v13-v16
    • (2006) Ann Oncol , vol.17 , Issue.SUPPL. 5
    • Rosell, R.1    Cobo, M.2    Isla, D.3
  • 95
    • 0042967714 scopus 로고    scopus 로고
    • Targeted therapy in combination with gemcitabine in non-small cell lung cancer
    • Rosell R, Crino L, Danenberg K et al. Targeted therapy in combination with gemcitabine in non-small cell lung cancer. Semin Oncol 2003; 30: 19-25
    • (2003) Semin Oncol , vol.30 , pp. 19-25
    • Rosell, R.1    Crino, L.2    Danenberg, K.3
  • 96
    • 34250843259 scopus 로고    scopus 로고
    • Weighing Tumor Biology in Treatment Decisions for Patients with Non-small Cell Lung Cancer
    • Shepherd FA, Rosell R. Weighing Tumor Biology in Treatment Decisions for Patients with Non-small Cell Lung Cancer. J Thorac Oncol 2007; 2: 68-76
    • (2007) J Thorac Oncol , vol.2 , pp. 68-76
    • Shepherd, F.A.1    Rosell, R.2
  • 97
    • 12144285914 scopus 로고    scopus 로고
    • Ribonucleotide reductase messenger RNA expression and survival in gemcitabine/cisplatin-treated advanced non-small cell lung cancer patients
    • Rosell R, Danenberg KD, Alberola V et al. Ribonucleotide reductase messenger RNA expression and survival in gemcitabine/cisplatin-treated advanced non-small cell lung cancer patients. Clin Cancer Res 2004; 10: 1318-1325
    • (2004) Clin Cancer Res , vol.10 , pp. 1318-1325
    • Rosell, R.1    Danenberg, K.D.2    Alberola, V.3
  • 98
    • 34447567414 scopus 로고    scopus 로고
    • Feasibility and efficacy of molecular analysis-directed individualized therapy in advanced non-small-cell lung cancer
    • Simon G, Sharma A, Li X et al. Feasibility and efficacy of molecular analysis-directed individualized therapy in advanced non-small-cell lung cancer. J Clin Oncol 2007; 25: 2741-2746
    • (2007) J Clin Oncol , vol.25 , pp. 2741-2746
    • Simon, G.1    Sharma, A.2    Li, X.3
  • 99
    • 34247097395 scopus 로고    scopus 로고
    • A phase II study of days 1 and 8 combination of docetaxel plus gemcitabine for the second-line treatment of patients with advanced non-small-cell lung cancer and good performance status
    • Cobo M, Gutierrez V, Alcaide J et al. A phase II study of days 1 and 8 combination of docetaxel plus gemcitabine for the second-line treatment of patients with advanced non-small-cell lung cancer and good performance status. Lung Cancer 2007; 56: 255-262
    • (2007) Lung Cancer , vol.56 , pp. 255-262
    • Cobo, M.1    Gutierrez, V.2    Alcaide, J.3
  • 100
    • 34447573875 scopus 로고    scopus 로고
    • Customizing cisplatin based on quantitative excision repair cross-complementing 1 mRNA expression: A phase III trial in non-small-cell lung cancer
    • Cobo M, Isla D, Massuti B et al. Customizing cisplatin based on quantitative excision repair cross-complementing 1 mRNA expression: a phase III trial in non-small-cell lung cancer. J Clin Oncol 2007; 25: 2747-2754
    • (2007) J Clin Oncol , vol.25 , pp. 2747-2754
    • Cobo, M.1    Isla, D.2    Massuti, B.3
  • 102
    • 23044435044 scopus 로고    scopus 로고
    • Expression of class III {beta}-tubulin is predictive of patient outcome in patients with non-small cell lung cancer receiving vinorelbine-based chemotherapy
    • Seve P, Isaac S, Tredan O et al. Expression of class III {beta}-tubulin is predictive of patient outcome in patients with non-small cell lung cancer receiving vinorelbine-based chemotherapy. Clin Cancer Res 2005; 11: 5481-5486
    • (2005) Clin Cancer Res , vol.11 , pp. 5481-5486
    • Seve, P.1    Isaac, S.2    Tredan, O.3
  • 103
    • 30344437279 scopus 로고    scopus 로고
    • Class III beta-tubulin expression in tumor cells predicts response and outcome in patients with non-small cell lung cancer receiving paclitaxel
    • Seve P, Mackey J, Isaac S et al. Class III beta-tubulin expression in tumor cells predicts response and outcome in patients with non-small cell lung cancer receiving paclitaxel. Mol Cancer Ther 2005; 4: 2001-2007
    • (2005) Mol Cancer Ther , vol.4 , pp. 2001-2007
    • Seve, P.1    Mackey, J.2    Isaac, S.3


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