Biological properties of TW01 cells expressing latent membrane protein-1 gene of EBV-derived from nasopharyngeal carcinoma cells at different stages of malignancy

Experimental Oncology

Volumn 29, Issue 3, 2007, Pages 166-174

  Tan, E L ^a   Sam, C K ^a  

^a UNIVERSITY OF MALAYA   (Malaysia)

Author keywords

Biological properties; Epstein Barr virus; LMP1 gene; Malignancy; Nasopharyngeal carcinoma

Indexed keywords

AMINO ACID; LATENT MEMBRANE PROTEIN 1; UVOMORULIN;

AMINO ACID SEQUENCE; APOPTOSIS; ARTICLE; CANCER STAGING; CARCINOMA CELL; CONTROLLED STUDY; DISEASE COURSE; EPSTEIN BARR VIRUS; GENE EXPRESSION; GENE FUNCTION; GENE MUTATION; GENE SEQUENCE; GENETIC REGULATION; GENETIC VARIABILITY; HUMAN; HUMAN CELL; IN VITRO STUDY; NASOPHARYNX CARCINOMA; NONHUMAN; NUCLEOTIDE SEQUENCE; PHENOTYPE; WILD TYPE;

AMINO ACID SEQUENCE; APOPTOSIS; CADHERINS; CELL LINE, TUMOR; FLUORESCENT ANTIBODY TECHNIQUE; GENES, VIRAL; HERPESVIRUS 4, HUMAN; HUMANS; MOLECULAR SEQUENCE DATA; NASOPHARYNGEAL NEOPLASMS; NEOPLASM INVASIVENESS; PRECANCEROUS CONDITIONS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; TRANSFECTION; VIRAL MATRIX PROTEINS;

EID: 36749100066     PISSN: 18129269     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (26)

1. Yi HM, Li H, Peng D, Zhang HJ, Wang L, Zhao M, Yao KT, Ren CP. Genetic and epigenetic alterations of LTF at 3p21.3 in nasopharyngeal carcinoma. Oncol Res 2006; 16: 261-72.
2. Rickinson AB, Moss DJ. Human cytotoxic T lymphocyte responses to Epstein - Barr virus infection. Ann Rev Immunol 1997, 15: 405-31.
3. Pathmanathan R, Prasad U, Sadler R, Flynn, K, Raab-Traub N. Clonal proliferations of cells infected with Epstein-Barr virus in preinvasive lesions related to nasopharyngeal carcinoma. New Engl J Med 1995; 333: 693-8.
4. Lin CT, Chan WY, Chen W, Huang HM, Wu HC, Hsu MM, Chuang SM, Wang CC. Characterization of seven newly established nasopharyngeal carcinoma cell lines. Lab Invest 1993; 68: 716-27.
5. Hu LF, Zabarovsky ER, Chen F, Cao SL, Ernberg I, Klein G, Winberg G. Isolation and sequencing of the Epstein - Barr virus BNLF-1 gene (LMP1) from a Chinese nasopharyngeal carcinoma. J Gen Virol 1991; 72: 2399-409.
6. Cheung ST, Leung SF, Lo KW, Chiu KW, Tam JS, Fok TF, Johnson PJ, Lee JC, Huang DP. Specific latent membrane protein 1 gene sequences in type 1 and type 2 Epstein - Barr virus from nasopharyngeal carcinoma in Hong Kong. Int J Can 1998; 76: 399-406.
7. Chen ML, Tsai CN, Liang CL, Shu CH, Huang CR, Sulitzeanu D, Liu ST, Chang YS. Cloning and characterization of the latent membrane protein (LMP) of a specific Epstein - Barr virus variant derived from the nasopharyngeal carcinoma in the Taiwanese population. Oncogene 1992, 7: 2131-40.
8. Sung NS, Edwards RH, Seillier-Moiseiwitsch F, Perkins AG, Zeng Y, Raab-Traub N. Epstein - Barr virus strain variation in nasopharyngeal carcinoma from the endemic and non-endemic regions of China. Int J Cancer 1998; 76: 207-15.
9. Edwards RH, Seillier-Moiseiwitsch F, Raab-Traub N. Signature amino acid changes in latent membrane protein 1 distinguish Epstein - Barr virus strains. Virology 1999; 261: 79-95.
10. Sample J, Kieff EF, Kieff ED. Epstein - Barr virus types 1 and 2 have nearly identical LMP-1 transforming genes. J Gen Virol 1994; 75: 2741-6.
11. Miller WE, Edwards RH, Walling DM, Raab-Traub N. Sequence variation in the Epstein - Barr virus latent membrane protein 1. J Gen Virol 1994; 75: 2729-40.
12. Hu LF, Chen F, Zhen QF, Zhang YW, Luo Y, Zheng X, Winberg G, Ernberg I, Klein, G. Differences in the growth pattern and clinical course of EBV-LMP1 expressing and non-expressing nasopharyngeal carcinomas. Eur J Cancer 1995; 31: 658-60.
13. Laherty CD, Hu HM, Opipari AW, Wang F, Dixit VM. The Epstein - Barr virus LMP1 gene product induces A20 zinc finger protein expression by activating nuclear factor kappa B. J Biol Chem 1992; 267: 24157-60.
14. Rowe M, Peng-Pilon M, Huen DS, Hardy R, Croom-Carter D, Lundgren E, Rickinson, AB. Upregulation of bcl-2 by the Epstein - Barr virus latent membrane protein LMP1: a B-cell-specific response that is delayed relative to NF-kappa B activation and to induction of cell surface markers. J Virol 1994; 68: 5602-12.
15. Li HP, Chang YS. Epstein - Barr virus latent membrane protein 1: structure and functions. J Biomed Sci 2003; 10: 490-504.
16. Tsai CN, Tsai CL, Tse KP, Chang HY, Chang YS. The Epstein - Barr virus oncogene product, latent membrane protein 1, induces the downregulation of E-cadherin gene expression via activation of DNA methyltransferases. Proc Natl Acad Sci USA 2002; 99: 10084-9.
17. Mansouri A, Spurr N, Goodfellow PN, Kemler R. Characterization and chromosomal localization of the gene encoding the human cell adhesion molecule uvomorulin. Differentiation 1998; 38: 67-71.
18. Baer R, Bankier AT, Biggin MD, Deininger PL, Farrell PJ, Gibson TJ, Hatfull G, Hudson GS, Satchwell SC, Séguin C, Tuffnell PS, Barrell BG. DNA sequence and expression of the B95-8 Epstein-Barr virus genome. Nature 1984, 310:207-11.
19. Pandya J, Walling DM. Epstein - Barr virus latent membrane protein 1 (LMP-1) half-life in epithelial cells is down-regulated by lytic LMP-1. J Virol 2004; 78: 8404-10.
20. Teramoto N, Maeda A, Kobayashi K, Hayashi K, Oka T, Takahashi K, Takada K, Klein G, Akagi T. Epstein - Barr virus infection to Epstein - Barr virus-negative nasopharyngeal carcinoma cell line TW03 enhances its tumorigenicity. Lab Invest 2000; 80: 303-12.
21. Yoshizaki T, Sato H, Murono S, Pagano JS, Furukawa M. Matrix metalloproteinase 9 is induced by the Epstein - Barr virus BZLF1 transactivator. Clin Exp Metastasis 1999; 17: 431-6.
22. Fahraeus R, Chen W, Trivedi P, Klein G, Obrink B. Decreased expression of E-cadherin and increased invasive capacity in EBV-LMP-transfected human epithelial and murine adenocarcinoma cells. Int J Cancer 1992; 52: 834-8.
23. Prasad U. Nasopharyngeal Carcinoma. Kuala Lumpur: University of Malaya Press, 2000.
24. Lo AK, Huang DP, Lo KW, Chui YL, O HM, Pang JC, Tsao SW. Phenotypic alterations induced by the Hong Kong-prevalent Epstein - Barr virus-encoded LMP1 variant (2117-LMP1) in nasopharyngeal epithelial cells. Int J Cancer 2004; 109: 919-25.
25. Edwards RH, Sitki-Green D, Moore DT, Raab-Traub N. Potential selection of LMP1 variants in nasopharyngeal carcinoma. J Virol 2004; 78: 868-81.
26. Janssen A, Johansson P, Li S, Rymo L. Activity of the LMP1 gene promoter in Epstein - Barr virus-transformed cell lines is modulated by sequence variations in the promoter-proximal CRE site. J Gen Virol 2007; 88: 1887-94.