Evaluation of two homologous proline-rich proteins of Coccidioides posadasii as candidate vaccines against coccidioidomycosis

Infection and Immunity

Volumn 75, Issue 12, 2007, Pages 5777-5787

  Herr, Roger A ^a,c   Hung, Chiung Yu ^b   Cole, Garry T ^b  

^a MEDICAL COLLEGE OF OHIO   (United States)

^b UNIVERSITY OF TEXAS AT SAN ANTONIO   (United States)

^c WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

FUNGAL PROTEIN; FUNGUS VACCINE; IMMUNOLOGICAL ADJUVANT; PROLINE RICH ANTIGEN; PROTEIN PRP2; PROTEIN RAG2 PRA; UNCLASSIFIED DRUG;

ADOLESCENT; AMINO ACID SEQUENCE; ANIMAL EXPERIMENT; ARTICLE; BAGG ALBINO MOUSE; C57BL 6 MOUSE; COCCIDIOIDES; COCCIDIOIDES POSADASII; COCCIDIOIDOMYCOSIS; CONTROLLED STUDY; ENZYME LINKED IMMUNOSPOT ASSAY; FEMALE; IMMUNOGENICITY; LUNG MYCOSIS; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN ANALYSIS; SEQUENCE HOMOLOGY; T LYMPHOCYTE;

ANIMALS; BASE SEQUENCE; CD4-POSITIVE T-LYMPHOCYTES; COCCIDIOIDES; COCCIDIOIDOMYCOSIS; EPITOPES, T-LYMPHOCYTE; FEMALE; FUNGAL PROTEINS; FUNGAL VACCINES; GLYCOPROTEINS; HUMANS; MICE; MICE, INBRED C57BL; MOLECULAR SEQUENCE DATA; PEPTIDES; PROLINE; PROTEIN CONFORMATION; VACCINES, SYNTHETIC;

EID: 36749088866     PISSN: 00199567     EISSN: None     Source Type: Journal    
DOI: 10.1128/IAI.00807-07     Document Type: Article

References (49)

1. Altschul, S. F., T. L. Madden, A. A. Schaffer, J. Zhang, Z. Zhang, W. Miller, and D. J. Lipman. 1997. Gapped BLAST and PSI-BLAST: a new generation of protein database search programs. Nucleic Acids Res. 25:3389-3402.
2. Awasthi, S. 2007. Dendritic cell-based vaccine against Coccidioides infection. Ann. N. Y. Acad. Sci. 1111:269-274.
3. Barnato, A. E., G. D. Sanders, and D. K. Owens. 2001. Cost-effectiveness of a potential vaccine for Coccidioides immitis. Emerg. Infect. Dis. 7:797-806.
4. Brady, L. J., D. G. Cvitkovitch, C. M. Geric, M. N. Addison, J. C. Joyce, P. J. Crowley, and A. S. Bleiweis. 1998. Deletion of the central proline-rich repeat domain results in altered antigenicity and lack of surface expression of the Streptococcus mutans P1 adhesin molecule. Infect. Immun. 66:4274-4282.
5. Casadevall, A., and L. A. Pirofski. 2006. The weapon potential of human pathogenic fungi. Med. Mycol. 44:689-696.
6. Cole, G. T., J. Xue, C. Okeke, E. Tarcha, V. Basrur, R. A. Schaller, R. A. Herr, J.-J. Yu, and C.-Y. Hung. 2004. A vaccine against coccidioidomycosis is justified and attainable. Med. Mycol. 42:189-216.
7. Comrie, A. C. 2005. Climate factors influencing coccidioidomycosis seasonality and outbreaks. Environ. Health Perspect. 113:688-692.
8. Cordeiro, R. A., R. S. Brilhante, M. F. Rocha, M. A. Fechine, L. M. Camara, Z. P. Camargo, and J. J. Sidrim. 2006. Phenotypic characterization and ecological features of Coccidioides spp. from Northeast Brazil. Med. Mycol. 44:631-639.
9. Cox, R. A., and L. A. Britt. 1985. Antigenic heterogeneity of an alkali-soluble, water-soluble cell wall extract of Coccidioides immitis. Infect. Immun. 50:365-369.
10. Cox, R. A., and D. M. Magee. 2004. Coccidioidomycosis: host response and vaccine development. Clin. Microbiol. Rev. 17:804-839.
11. Cutler, J. E., G. S. Deepe, Jr., and B. S. Klein. 2007. Advances in combating fungal diseases: vaccines on the threshold. Nat. Rev. Microbiol. 5:13-28.
12. Delgado, N., J. Xue, J.-J. Yu, C.-Y. Hung, and G. T. Cole. 2003. A recombinant beta-1,3-glucanosyltransferase homolog of Coccidioides posadasii protects mice against coccidioidomycosis. Infect. Immun. 71:3010-3019.
13. Dixon, D. M. 2001. Coccidioides immitis as a select agent of bioterrorism. J. Appl. Microbiol. 91:602-605.
14. Dugger, K. O., J. N. Galgiani, N. M. Ampel, S. H. Sun, D. M. Magee, J. Harrison, and J. H. Law. 1991. An immunoreactive apoglycoprotein purified from Coccidioides immitis. Infect. Immun. 59:2245-2251.
15. Dugger, K. O., K. M. Villareal, A. Ngyuen, C. R. Zimmermann, J. H. Law, and J. N. Galgiani. 1996. Cloning and sequence analysis of the cDNA for a protein from Coccidioides immitis with immunogenic potential. Biochem. Biophys. Res. Commun. 218:485-489.
16. + T cells can mediate vaccine-induced protection against Coccidioides immitis infection in mice. J. Infect. Dis. 193:1323-1331.
17. Fisher, M. C., G. L. Koenig, T. J. White, and J. W. Taylor. 2002. Molecular and phenotypic description of Coccidioides posadasii sp. nov., previously recognized as the non-California population of Coccidioides immitis. Mycologia 94:73-84.
18. Galgiani, J. N., S. H. Sun, K. O. Dugger, N. M. Ampel, G. G. Grace, J. Harrison, and M. A. Wieden. 1992. An arthroconidial-spherule antigen of Coccidioides immitis: differential expression during in vitro fungal development and evidence for humoral response in humans after infection or vaccination. Infect. Immun. 60:2627-2635.
19. Guevara-Olvera, L., C.-Y. Hung, J.-J. Yu, and G. T. Cole. 2000. Sequence, expression and functional analysis of the Coccidioides immitis ODC (ornithine decarboxylase) gene. Gene 242:437-448.
20. Hector, R. F., and R. Laniado-Laborin. 2005. Coccidioidomycosis - a fungal disease of the Americas. PLoS Med. 2:15-18.
21. Hung, C.-Y., K. R. Seshan, J.-J. Yu, R. Schaller, J. Xue, V. Basrur, M. J. Gardner, and G. T. Cole. 2005. Metalloproteinase of Coccidioides posadasii contributes to evasion of host detection. Infect. Immun. 73:6689-6703.
22. Hung, C.-Y., J.-J. Yu, P. F. Lehmann, and G. T. Cole. 2001. Cloning and expression of the gene which encodes a tube precipitin antigen and wall-associated β-glucosidase of Coccidioides immitis. Infect. Immun. 69:2211-2222.
23. Hung, C.-Y., J.-J. Yu, K. R. Seshan, U. Reichard, and G. T. Cole. 2002. A parasitic phase-specific adhesin of Coccidioides immitis contributes to the virulence of this respiratory fungal pathogen. Infect. Immun. 70:3443-3456.
24. Jiang, C., D. M. Magee, F. D. Ivey, and R. A. Cox. 2002. Role of signal sequence in vaccine-induced protection against experimental coccidioidomycosis. Infect. Immun. 70:3539-3545.
25. Jiang, C., D. M. Magee, T. N. Quitugua, and R. A. Cox. 1999. Genetic vaccination against Coccidioides immitis: comparison of vaccine efficacy of recombinant antigen 2 and antigen 2 cDNA. Infect. Immun. 67:630-635.
26. Julenius, K., A. Molgaard, R. Gupta, and S. Brunak. 2005. Prediction, conservation analysis, and structural characterization of mammalian mucin-type O-glycosylation sites. Glycobiology 15:153-164.
27. Kirkland, T. N., and G. T. Cole. 2002. Coccidioidomycosis: pathogenesis, immune response and vaccine development, p. 365-399. In R. A. Calderone and L. C. Cihlar (ed.), Fungal pathogenesis: principles and applications. Marcel Dekker, New York, NY.
28. Kirkland, T. N., and J. Fierer. 1983. Inbred mouse strains differ in resistance to lethal Coccidioides immitis infection. Infect. Immun. 40:912-916.
29. Kirkland, T. N., F. Finley, K. I. Orsborn, and J. N. Galgiani. 1998. Evaluation of the proline-rich antigen of Coccidioides immitis as a vaccine candidate in mice. Infect. Immun. 66:3519-3522.
30. Kulkarni, R. D., H. S. Kelkar, and R. A. Dean. 2003. An eight-cysteine-containing CFEM domain unique to a group of fungal membrane proteins. Trends Biochem. Sci. 28:118-121.
31. Leach, M. R., J. W. Zhang, and D. B. Zamble. 2007. The role of complex formation between the Escherichia coli hydrogenase accessory factors HYPB and SlyD. J. Biol. Chem. 282:16177-16182.
32. Li, K., J.-J. Yu, C.-Y. Hung, P. F. Lehmann, and G. T. Cole. 2001. Recombinant urease and urease DNA of Coccidioides immitis elicit an immunoprotective response against coccidioidomycosis in mice. Infect. Immun. 69:2878-2887.
33. MacArthur, M. W., and J. M. Thornton. 1991. Influence of proline residues on protein conformation. J. Mol. Biol. 218:397-412.
34. Magee, D. M., R. L. Friedberg, M. D. Woitaske, S. A. Johnston, and R. A. Cox. 2005. Role of B cells in vaccine-induced immunity against coccidioidomycosis. Infect. Immun. 73:7011-7013.
35. McGinnis, M. R., M. B. Smith, and E. Hinson. 2006. Use of the Coccidioides posadasii Δchs5 strain for quality control in the ACCUPROBE culture identification test for Coccidioides immitis. J. Clin. Microbiol. 44:4250-4251.
36. Morrow, W. 2006. Holocene coccidioidomycosis: valley fever in early Holocene bison (Bison antiquus). Mycologia 98:669-677.
37. Notredame, C., D. Higgins, and J. Heringa. 2000. T-Coffee: a novel method for multiple sequence alignments. J. Mol. Biol. 302:205-217.
38. Orsborn, K. I., and J. N. Galgiani. 1998. Detecting serum antibodies to a purified recombinant proline-rich antigen of Coccidioides immitis in patients with coccidioidomycosis. Clin. Infect. Dis. 27:1475-1478.
39. Peng, T., L. Shubitz, J. Simons, R. Perrill, K. I. Orsborn, and J. N. Galgiani. 2002. Localization within a proline-rich antigen (Ag2/PRA) of protective antigenicity against infection with Coccidioides immitis in mice. Infect. Immun. 70:3330-3335.
40. Roof, W. D., S. M. Horne, K. D. Young, and R. Young. 1994. SlyD, a host gene required for phiX174 lysis, is related to the FK506-binding protein family of peptidyl-prolyl cis-trans-isomerases. J. Biol. Chem. 269:2902-2910.
41. Shubitz, L., T. Peng, R. Perrill, J. Simons, K. Orsborn, and J. N. Galgiani. 2002. Protection of mice against Coccidioides immitis intranasal infection by vaccination with recombinant antigen 2/PRA. Infect. Immun. 70:3287-3289.
42. Shubitz, L. F., J.-J. Yu, C.-Y. Hung, T. N. Kirkland, T. Peng, R. Perrill, J. Simons, J. Xue, R. A. Herr, G. T. Cole, and J. N. Galgiani. 2006. Improved protection of mice against lethal respiratory infection with Coccidioides posadasii using two recombinant antigens expressed as a single protein. Vaccine 24:5904-5911.
43. Tarcha, E. J., V. Basrur, C.-Y. Hung, M. J. Gardner, and G. T. Cole. 2006. A recombinant aspartyl protease of Coccidioides posadasii induces protection against pulmonary coccidioidomycosis in mice. Infect. Immun. 74:516-527.
44. Tarcha, E. J., V. Basrur, C. Y. Hung, M. J. Gardner, and G. T. Cole. 2006. Multivalent recombinant protein vaccine against coccidioidomycosis. Infect. Immun. 74:5802-5813.
45. Thompson, J. D., D. G. Higgins, and T. J. Gibson. 1994. CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice. Nucleic Acids Res. 22:4673-4680.
46. Warnock, D. W. 2006. Fungal diseases: an evolving public health challenge. Med. Mycol. 44:697-705.
47. Yu, J.-J., L. Zhang, P. W. Thomas, P. J. Szaniszlo, and G. T. Cole. 1999. Isolation and confirmation of function of the Coccidioides immitis URA5 (orotate phosphoribosyl transferase) gene. Gene 226:233-242.
48. Zhu, Y., V. Tryon, D. M. Magee, and R. A. Cox. 1997. Identification of a Coccidioides immitis antigen 2 domain that expresses B-cell-reactive epitopes. Infect. Immun. 65:3376-3380.
49. Zhu, Y., C. Yang, D. M. Magee, and R. A. Cox. 1996. Coccidioides immitis antigen 2: analysis of gene and protein. Gene 181:121-125.