Water-soluble polymer formation of monodispersed insulin microspheres

ACS Symposium Series

Volumn 924, Issue , 2006, Pages 329-339

  Brown, Larry ^a   Qin, Yuanxi ^a   Hogeland, Kenneth ^a   McGeehan, John ^a   Mason, Kathy ^a   Jeannotte, Travis ^a   Fortier, Robert ^a   Moore, Eric ^a  

^a BAXTER HEALTHCARE CORPORATION   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 36749087587     PISSN: 00976156     EISSN: None     Source Type: Book Series    
DOI: None     Document Type: Conference Paper

References (9)

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2. Laurent, T.C. The interaction between polysaccharides and macromolecules 5. The solubility of proteins in the presence of dextran. Biochem. J. 1963, 89, 253-257.
3. Casillas, G.; Simonetti, C. Polyvinylpyrrolidone (PVP): A new precipitating agent for human and bovine factor VIII and fibrinogen. British J. Haemat. 1982, 50, 665-672.
4. Atha D.H.; Ingham K.C. Mechanism of precipitation of proteins by polyethylene glycols. Analysis in terms of excluded volume. J. Biol. Chem. 1981, 256, 12108-12117.
5. Brown, L.; Jarpe, M.; McGeehan, J.; Qin, Y.; Moore, E.; Hogeland, K. PROMAXX microsphere characterization. Resp. Drug. Del. 2004, IX, 477-480.
6. Rashba-Step, J.; Brown, L.; Hogeland, K.; McGeehan, J.; Proos, R.; Rulon, P.; Sullivan, A.; Scott, T. Albumin microspheres as a drug delivery vehicle for multiple routes of administration. Proc. Int. Symp. Control. Rel. Bioact. Mater. 2001, 28, 1001-1002.
7. USP 25, Official Monographs 2002, p. 911.
8. Byron, P.R. Prediction of drug residence times in regions of the human respiratory tract following aerosol inhalation. J. Pharm. Sci. 1986, 75, 433-438.
9. Skyler, J.S.; Cefalu, W.T.; Kourides, I.A.; Landschulz, W.H.; Balagtas CC; Cheng, S.; Gelfand, R.A. Efficacy of inhaled human insulin in type 1 diabetes mellitus: A randomized proof-of-concept study. The Lancet 2001, 357, 331-335.